Search Result

Results for "

hydroxycinnamic acid

" in MedChemExpress (MCE) Product Catalog:

By Targets:	AMPK (1) Apoptosis (5) Bacterial (5) Calcium Channel (1) Cholinesterase (ChE) (1) COMT (2) Drug Derivative (2) Endogenous Metabolite (12) ERK (1) HIV (3) Isotope-Labeled Compounds (2) JNK (1) Melanocortin Receptor (1) MMP (1) Monocarboxylate Transporter (3) p38 MAPK (1) PDGFR (1) PERK (1) Phosphatase (1) Prostaglandin Receptor (2) Reactive Oxygen Species (ROS) (2) Reference Standards (6) SARS-CoV (4) TGF-beta/Smad (1) Tyrosinase (3)
By Research Areas:	Cancer (11) Cardiovascular Disease (4) Endocrinology (2) Infection (4) Inflammation/Immunology (9) Metabolic Disease (7) Neurological Disease (4)

By Targets:

AMPK (1)

Apoptosis (5)

Bacterial (5)

Calcium Channel (1)

Cholinesterase (ChE) (1)

COMT (2)

Drug Derivative (2)

Endogenous Metabolite (12)

ERK (1)

HIV (3)

Isotope-Labeled Compounds (2)

JNK (1)

Melanocortin Receptor (1)

MMP (1)

Monocarboxylate Transporter (3)

p38 MAPK (1)

PDGFR (1)

PERK (1)

Phosphatase (1)

Prostaglandin Receptor (2)

Reactive Oxygen Species (ROS) (2)

Reference Standards (6)

SARS-CoV (4)

TGF-beta/Smad (1)

Tyrosinase (3)

By Research Areas:

Cancer (11)

Cardiovascular Disease (4)

Endocrinology (2)

Infection (4)

Inflammation/Immunology (9)

Metabolic Disease (7)

Neurological Disease (4)

Inhibitors & Agonists

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-107641

*α-Cyano-4-hydroxycinnamic* acid** Maximum Cited Publications 11 Publications Verification α-Cyano-4-hydroxycinnamate	Monocarboxylate Transporter	Metabolic Disease
α-Cyano-4-hydroxycinnamic acid (α-Cyano-4-hydroxycinnamate) is a potent and non-competitive inhibitor of monocarboxylate transporters (MCTs). α-Cyano-4-hydroxycinnamic acid inhibits mitochondrial pyruvate transporter with a K_i of 6.3 μM. α-Cyano-4-hydroxycinnamic acid is used as a matrix to facilitate peptide ionization in matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry applications .

HY-N0351

p-Coumaric acid 3 Publications Verification trans-4-hydroxycinnamic acid	Endogenous Metabolite Bacterial Apoptosis	Inflammation/Immunology Cancer
p-Coumaric acid (trans-4-Hydroxycinnamic acid) is an isomer of cinnamic acid with oral activity. p-Coumaric acid inhibits cell proliferation and promotes apoptosis. p-Coumaric acid has antibacterial, anti-inflammatory, antioxidant and anti-tumor activities .

HY-W012531

*2-Hydroxycinnamic* acid** 1 Publications Verification	HIV SARS-CoV Endogenous Metabolite Bacterial	Infection Neurological Disease Inflammation/Immunology Cancer
2-Hydroxycinnamic acid is a phenolic acid with antimicrobial and antioxidant properties. 2-Hydroxycinnamic acid has antimicrobial activity against *Staphylococcus aureus* and is not susceptible to drug resistance. 2-Hydroxycinnamic acid shows inhibitory effects on infection of HIV/SARS-CoV S pseudovirus with an IC₅₀ of 0.3 mM. In addition, 2-Hydroxycinnamic acid has neuroprotective and antitumor activity .

HY-133068

5-Hydroxyferulic acid	COMT Endogenous Metabolite	Others
5-Hydroxyferulic acid is a hydroxycinnamic acid and is a metabolite of the phenylpropanoid pathway. 5-Hydroxyferulic acid is a precursor in the biosynthesis of sinapic acid and is also a COMT non-esterifed substrate .

HY-N2391

*p-Hydroxycinnamic* acid**	Endogenous Metabolite Prostaglandin Receptor	Endocrinology
p-Hydroxycinnamic acid, a common dietary phenol, could inhibit platelet activity, with IC₅₀s of 371 μM, 126 μM for thromboxane B₂ production and lipopolysaccharide-induced prostaglandin E₂ generation, respectively.

HY-N3266

Methyl rosmarinate	Tyrosinase Phosphatase Cholinesterase (ChE) SARS-CoV PERK JNK p38 MAPK TGF-beta/Smad Apoptosis Reactive Oxygen Species (ROS) AMPK MMP	Cardiovascular Disease Infection Neurological Disease Inflammation/Immunology Cancer
Methyl rosmarinate is an orally active hydroxycinnamic acid. Methyl rosmarinate exhibits an IC₅₀ of 24.70 μM and a K_i of 15.29 μM against PTP1B, an IC₅₀ of 41.46 μg/mL against BChE, a K_i of 0.61 mM against mushroom tyrosinase, and an IC₅₀ of 2.50 μM against SARS-CoV-2 3CLpro. Methyl rosmarinate downregulates the phosphorylation levels of ERK, JNK, p38, Smad2 and Smad3. Methyl rosmarinate activates erythrocyte BPGM and promotes the production of 2,3-BPG. Methyl rosmarinate induces apoptosis of fibroblasts. Methyl rosmarinate prolongs the survival time of hypoxic mice. Methyl rosmarinate improves insulin sensitivity. Methyl rosmarinate binds to SARS-CoV-2 3CLpro and inhibits viral replication. Methyl rosmarinate induces glioblastoma cell death. Methyl rosmarinate activates the TGR5/AMPK axis and reduces the levels of ROS and MDA. Methyl rosmarinate shows inhibitory activity against MMP-1. Methyl rosmarinate can be used in research related to pulmonary fibrosis, hypoxia-induced injury, type 2 diabetes, Alzheimer's disease, hyperpigmentation disorders, COVID-19, glioblastoma and myocardial ischemia-reperfusion injury .

HY-N0351R

p-Coumaric acid (Standard) trans-4-hydroxycinnamic acid (Standard)	Reference Standards Endogenous Metabolite Bacterial Apoptosis	Inflammation/Immunology Cancer
p-Coumaric acid (Standard) is the analytical standard of p-Coumaric acid. This product is intended for research and analytical applications. p-Coumaric acid (trans-4-Hydroxycinnamic acid) is an isomer of cinnamic acid with oral activity. p-Coumaric acid inhibits cell proliferation and promotes apoptosis. p-Coumaric acid has antibacterial, anti-inflammatory, antioxidant and anti-tumor activities .

HY-N0351S1

p-Coumaric acid-d6 1 Publications Verification trans-4-hydroxycinnamic acid-d₆	Endogenous Metabolite	Cancer
p-Coumaric acid-d₆ is the deuterium labeled p-Coumaric acid (HY-N0351). p-Coumaric acid is the abundant isomer of cinnamic acid which has antitumor and anti-mutagenic activities .

HY-N7929

5-Feruloylquinic acid	Tyrosinase	Cancer
5-Feruloylquinic acid (5-FQA) is a hydroxycinnamic acid derivative. 5-Feruloylquinic acid can be isolated from green coffee beans. 5-Feruloylquinic acid inhibits tyrosinase activity. 5-Feruloylquinic acid has antioxidant properties. 5-Feruloylquinic acid has anticancer activity against lymphoma, oral epidermal cancer, and breast cancer .

HY-N7127

(E)-m-Coumaric acid	Endogenous Metabolite	Cardiovascular Disease Inflammation/Immunology Cancer
(E)-m-Coumaric acid (3-Hydroxycinnamic acid) is an aromatic acid that highly abundant in food. (E)-m-Coumaric acid (3-Hydroxycinnamic acid) is an antioxidant.

HY-118824A

N-Feruloylserotonin (E/Z)-Moschamine	Calcium Channel PDGFR ERK	Cardiovascular Disease Inflammation/Immunology
N-Feruloylserotonin ((E/Z)-Moschamine) is a serotonin hydroxycinnamic acid amide. It can be isolated from a variety of plants, particularly the seeds of safflower (Carthamus tinctorius L.). N-Feruloylserotonin inhibits KCl- and 5-HT-induced elevation of intracellular [Ca ²⁺]_i. It suppresses PDGF-BB-induced phosphorylation of PDGFRβ and ERK1/2. N-Feruloylserotonin exerts anti-inflammatory effects on aortic endothelial cells. It inhibits atherosclerotic plaque formation in apolipoprotein E-deficient mice .

HY-N0351A

cis-p-Coumaric acid cis-4-hydroxycinnamic acid	Apoptosis	Metabolic Disease
cis-p-Coumaric acid (cis-4-Hydroxycinnamic acid) is the cis-form of p-Coumaric acid (HY-N0351), which is higher in viable seeds of groundnuts than in non-viable ones. p-Coumaric acid is an isomer of cinnamic acid with oral activity. p-Coumaric acid inhibits cell proliferation and promotes Apoptosis .

HY-N12267

N,N′-Diferuloylputrescine (E/Z)-Terrestribisamide	Melanocortin Receptor	Metabolic Disease
N,N′-Diferuloylputrescine ((E/Z)-Terrestribisamide) is a inhibitor of pigmentation with 57% reduction. N,N′-Diferuloylputrescine significantly reduces the protein level of MITF. N,N′-Diferuloylputrescine has strong antioxidant activities as radical scavengers against reactive oxygen species .

HY-N3265

Methyl sinapate MSA	Others	Others
Methyl sinapate (MSA), a hydroxycinnamic acid, is a natural UV screening agent .

HY-W012531R

*2-Hydroxycinnamic* acid (Standard)**	Reference Standards HIV SARS-CoV Endogenous Metabolite Bacterial	Infection Neurological Disease Inflammation/Immunology Cancer
2-Hydroxycinnamic acid (Standard) is the analytical standard of 2-Hydroxycinnamic acid. This product is intended for research and analytical applications. 2-Hydroxycinnamic acid is a phenolic acid with antimicrobial and antioxidant properties. 2-Hydroxycinnamic acid has antimicrobial activity against *Staphylococcus aureus* and is not susceptible to drug resistance. 2-Hydroxycinnamic acid shows inhibitory effects on infection of HIV/SARS-CoV S pseudovirus with an IC₅₀ of 0.3 mM. In addition, 2-Hydroxycinnamic acid has neuroprotective and antitumor activity .

HY-N12216

Cyanidin 3-sophoroside-5-glucoside	Others	Others
Cyanidin 3-sophoroside-5-glucoside is the main anthocyanin in purple-fleshed sweet potato and affects the antioxidant activity of purple-fleshed sweet potato .

HY-133068A

(E)-5-Hydroxyferulic acid	COMT	Metabolic Disease
(E)-5-Hydroxyferulic acid is the E-isomer of 5-Hydroxyferulic acid (HY-133068). 5-hydroxyferulic acid is a hydroxycinnamic acid and is a metabolite of the phenylpropanoid pathway. 5-Hydroxyferulic acid is a precursor in the biosynthesis of sinapic acid and is also a COMT non-esterifed substrat .

HY-W012531S2

*2-Hydroxycinnamic* acid-d4**	Isotope-Labeled Compounds Bacterial Endogenous Metabolite SARS-CoV HIV	Infection Neurological Disease Inflammation/Immunology Cancer
2-Hydroxycinnamic acid-d₄ is deuterium labeled 2-Hydroxycinnamic acid. 2-Hydroxycinnamic acid is a phenolic acid with antimicrobial and antioxidant properties. 2-Hydroxycinnamic acid has antimicrobial activity against *Staphylococcus aureus* and is not susceptible to drug resistance. 2-Hydroxycinnamic acid shows inhibitory effects on infection of HIV/SARS-CoV S pseudovirus with an IC₅₀ of 0.3 mM. In addition, 2-Hydroxycinnamic acid has neuroprotective and antitumor activity .

HY-N12506

Cimicifugic acid F	Others	Others
Cimicifugic acid F is a hydroxycinnamic acid ester of piscidic acid isolated from the rhizomes of Cimicifuga racemosa.

HY-N2391R

*p-Hydroxycinnamic* acid (Standard)**	Reference Standards Endogenous Metabolite Prostaglandin Receptor	Endocrinology
p-Hydroxycinnamic acid, a common dietary phenol, could inhibit platelet activity, with IC50s of 371 μM, 126 μM for thromboxane B2 production and lipopolysaccharide-induced prostaglandin E2 generation, respectively.

HY-N0025

Jionoside D	Reactive Oxygen Species (ROS) Apoptosis	Metabolic Disease
Jionoside D is a hydroxycinnamic acid ester with antioxidant property. Jionoside D has scavenging activity of intracellular reactive oxygen species (ROS) and of DPPH radical, and lipid peroxidation inhibitory activity. Jionoside D reduces the apoptotic cells induced by H₂O₂ in V79-4 cells. Jionoside D increases the activities of cellular antioxidant enzymes, SOD and catalase .

HY-N7127R

(E)-m-Coumaric acid (Standard)	Reference Standards Endogenous Metabolite	Cardiovascular Disease Inflammation/Immunology Cancer
(E)-m-Coumaric acid (Standard) is the analytical standard of (E)-m-Coumaric acid. This product is intended for research and analytical applications. (E)-m-Coumaric acid (3-Hydroxycinnamic acid) is an aromatic acid that highly abundant in food. (E)-m-Coumaric acid (3-Hydroxycinnamic acid) is an antioxidant.

HY-N7929R

5-Feruloylquinic acid (Standard)	Reference Standards Tyrosinase	Cancer
5-Feruloylquinic acid (Standard) is the analytical standard of 5-Feruloylquinic acid (HY-N7929). This product is intended for research and analytical applications. 5-Feruloylquinic acid (5-FQA) is a hydroxycinnamic acid derivative. 5-Feruloylquinic acid can be isolated from green coffee beans. 5-Feruloylquinic acid inhibits tyrosinase activity. 5-Feruloylquinic acid has antioxidant properties. 5-Feruloylquinic acid has anticancer activity against lymphoma, oral epidermal cancer, and breast cancer .

HY-107641R

*α-Cyano-4-hydroxycinnamic* acid (Standard)** α-Cyano-4-hydroxycinnamate (Standard)	Reference Standards Monocarboxylate Transporter	Metabolic Disease
α-Cyano-4-hydroxycinnamic acid (Standard) is the analytical standard of α-Cyano-4-hydroxycinnamic acid (HY-107641). This product is intended for research and analytical applications. α-Cyano-4-hydroxycinnamic acid (α-Cyano-4-hydroxycinnamate) is a potent and non-competitive inhibitor of monocarboxylate transporters (MCTs). α-Cyano-4-hydroxycinnamic acid inhibits mitochondrial pyruvate transporter with a K_i of 6.3 μM. α-Cyano-4-hydroxycinnamic acid is used as a matrix to facilitate peptide ionization in matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry applications .

HY-107641S

*α-Cyano-4-hydroxycinnamic* acid-d4** α-Cyano-4-hydroxycinnamate-d₄	Isotope-Labeled Compounds Monocarboxylate Transporter	Metabolic Disease
α-Cyano-4-hydroxycinnamic acid-d₄ (α-Cyano-4-hydroxycinnamate-d₄) is the deuterium labeled α-Cyano-4-hydroxycinnamic acid (HY-107641). α-Cyano-4-hydroxycinnamic acid (α-Cyano-4-hydroxycinnamate) is a potent and non-competitive inhibitor of monocarboxylate transporters (MCTs). α-Cyano-4-hydroxycinnamic acid inhibits mitochondrial pyruvate transporter with a K_i of 6.3 μM. α-Cyano-4-hydroxycinnamic acid is used as a matrix to facilitate peptide ionization in matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry applications .

HY-N12302A

(E/Z)-Scotanamine D (E/Z)-N1-Dihydrocaffeoyl, N10-caffeoyl spermidine	Drug Derivative	Others
(E/Z)-Scotanamine D is a hydroxycinnamic acid amide found in the roots of Scopolia tangutica. (E/Z)-Scotanamine D is inactive against μ-, δ-, and κ-opioid receptors .

HY-N17535

Caffeoyltartaric acid	Others	Others
Caffeoyltartaric acid is an allelochemical. Caffeoyltartaric acid can be isolated from the residues of Agave lechuguilla. Caffeoyltartaric acid exhibits allelopathic activity .

HY-N18287

Tenuifoliose Q	Drug Derivative	Others
Tenuifoliose Q is an oligosaccharide ester esterified with acetic acid, benzoic acid and p-hydroxycinnamic acid, which can be isolated from the root bark of Polygala tenuifolia Willd .

HY-N17762

p-Coumaroyl-N-tryptophan	Others	Others
p-Coumaroyl-N-tryptophan is a hydroxycinnamic acid amide compound that can be isolated from coffee beans (Coffea arabica, Coffea canephora, Coffea liberica). p-Coumaroyl-N-tryptophan can be used to differentiate Robusta coffee from other coffee varieties.

HY-W726472

N-(E-4-Coumaroyl)-aspartate	Endogenous Metabolite	Others
N-(E-4-Coumaroyl)-aspartate is a hydroxycinnamic acid amide compound that can be isolated from Arabidopsis thaliana cell suspension cultures. N-(E-4-Coumaroyl)-aspartate may be involved in metabolic processes related to specific metabolites found in Arabidopsis thaliana cell cultures.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N0351

p-Coumaric acid 3 Publications Verification trans-4-hydroxycinnamic acid	Monophenols Microorganisms other families Classification of Application Fields Simple Phenylpropanols Phenols Phenylpropanoids Plants Endogenous metabolite Disease Research Fields Source Classification Cancer	Endogenous Metabolite Bacterial Apoptosis
p-Coumaric acid (trans-4-Hydroxycinnamic acid) is an isomer of cinnamic acid with oral activity. p-Coumaric acid inhibits cell proliferation and promotes apoptosis. p-Coumaric acid has antibacterial, anti-inflammatory, antioxidant and anti-tumor activities .

HY-W012531

*2-Hydroxycinnamic* acid** 1 Publications Verification	Infection Structural Classification Monophenols Cinnamomum cassia (L.) D. Don Classification of Application Fields Simple Phenylpropanols Phenols Phenylpropanoids Plants Lauraceae Disease Research Fields Source Classification	HIV SARS-CoV Endogenous Metabolite Bacterial
2-Hydroxycinnamic acid is a phenolic acid with antimicrobial and antioxidant properties. 2-Hydroxycinnamic acid has antimicrobial activity against *Staphylococcus aureus* and is not susceptible to drug resistance. 2-Hydroxycinnamic acid shows inhibitory effects on infection of HIV/SARS-CoV S pseudovirus with an IC₅₀ of 0.3 mM. In addition, 2-Hydroxycinnamic acid has neuroprotective and antitumor activity .

HY-133068

5-Hydroxyferulic acid	other families Classification of Application Fields Ketones, Aldehydes, Acids Other Diseases Phenols Polyphenols Plants Disease Research Fields Source Classification	COMT Endogenous Metabolite
5-Hydroxyferulic acid is a hydroxycinnamic acid and is a metabolite of the phenylpropanoid pathway. 5-Hydroxyferulic acid is a precursor in the biosynthesis of sinapic acid and is also a COMT non-esterifed substrate .

HY-N2391

*p-Hydroxycinnamic* acid**	Monophenols Classification of Application Fields Ketones, Aldehydes, Acids Phenols Endogenous metabolite Disease Research Fields Endocrinology Source Classification	Endogenous Metabolite Prostaglandin Receptor
p-Hydroxycinnamic acid, a common dietary phenol, could inhibit platelet activity, with IC₅₀s of 371 μM, 126 μM for thromboxane B₂ production and lipopolysaccharide-induced prostaglandin E₂ generation, respectively.

HY-N3266

Methyl rosmarinate	Structural Classification Classification of Application Fields Simple Phenylpropanols Adenocarpus cincinnatus (Ball) Maire Labiatae Phenols Polyphenols Phenylpropanoids Plants Disease Research Fields Source Classification Cancer	Tyrosinase Phosphatase Cholinesterase (ChE) SARS-CoV PERK JNK p38 MAPK TGF-beta/Smad Apoptosis Reactive Oxygen Species (ROS) AMPK MMP
Methyl rosmarinate is an orally active hydroxycinnamic acid. Methyl rosmarinate exhibits an IC₅₀ of 24.70 μM and a K_i of 15.29 μM against PTP1B, an IC₅₀ of 41.46 μg/mL against BChE, a K_i of 0.61 mM against mushroom tyrosinase, and an IC₅₀ of 2.50 μM against SARS-CoV-2 3CLpro. Methyl rosmarinate downregulates the phosphorylation levels of ERK, JNK, p38, Smad2 and Smad3. Methyl rosmarinate activates erythrocyte BPGM and promotes the production of 2,3-BPG. Methyl rosmarinate induces apoptosis of fibroblasts. Methyl rosmarinate prolongs the survival time of hypoxic mice. Methyl rosmarinate improves insulin sensitivity. Methyl rosmarinate binds to SARS-CoV-2 3CLpro and inhibits viral replication. Methyl rosmarinate induces glioblastoma cell death. Methyl rosmarinate activates the TGR5/AMPK axis and reduces the levels of ROS and MDA. Methyl rosmarinate shows inhibitory activity against MMP-1. Methyl rosmarinate can be used in research related to pulmonary fibrosis, hypoxia-induced injury, type 2 diabetes, Alzheimer's disease, hyperpigmentation disorders, COVID-19, glioblastoma and myocardial ischemia-reperfusion injury .

HY-N0351R

p-Coumaric acid (Standard) trans-4-hydroxycinnamic acid (Standard)	Structural Classification Monophenols Microorganisms other families Simple Phenylpropanols Phenols Phenylpropanoids Plants Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite Bacterial Apoptosis
p-Coumaric acid (Standard) is the analytical standard of p-Coumaric acid. This product is intended for research and analytical applications. p-Coumaric acid (trans-4-Hydroxycinnamic acid) is an isomer of cinnamic acid with oral activity. p-Coumaric acid inhibits cell proliferation and promotes apoptosis. p-Coumaric acid has antibacterial, anti-inflammatory, antioxidant and anti-tumor activities .

HY-N7929

5-Feruloylquinic acid	Monophenols other families Classification of Application Fields Ketones, Aldehydes, Acids Other Phenylpropanoids Phenols Phenylpropanoids Plants Disease Research Fields Source Classification Cancer	Tyrosinase
5-Feruloylquinic acid (5-FQA) is a hydroxycinnamic acid derivative. 5-Feruloylquinic acid can be isolated from green coffee beans. 5-Feruloylquinic acid inhibits tyrosinase activity. 5-Feruloylquinic acid has antioxidant properties. 5-Feruloylquinic acid has anticancer activity against lymphoma, oral epidermal cancer, and breast cancer .

HY-N7127

(E)-m-Coumaric acid	Cardiovascular Disease Monophenols Classification of Application Fields Ketones, Aldehydes, Acids Phenols Endogenous metabolite Inflammation/Immunology Disease Research Fields Source Classification	Endogenous Metabolite
(E)-m-Coumaric acid (3-Hydroxycinnamic acid) is an aromatic acid that highly abundant in food. (E)-m-Coumaric acid (3-Hydroxycinnamic acid) is an antioxidant.

HY-118824A

N-Feruloylserotonin (E/Z)-Moschamine	Cardiovascular Disease Alkaloids Structural Classification Classification of Application Fields Carthamus tinctorius L. Phenols Polyphenols Plants Compositae Disease Research Fields Indole Alkaloids Source Classification	Calcium Channel PDGFR ERK
N-Feruloylserotonin ((E/Z)-Moschamine) is a serotonin hydroxycinnamic acid amide. It can be isolated from a variety of plants, particularly the seeds of safflower (Carthamus tinctorius L.). N-Feruloylserotonin inhibits KCl- and 5-HT-induced elevation of intracellular [Ca ²⁺]_i. It suppresses PDGF-BB-induced phosphorylation of PDGFRβ and ERK1/2. N-Feruloylserotonin exerts anti-inflammatory effects on aortic endothelial cells. It inhibits atherosclerotic plaque formation in apolipoprotein E-deficient mice .

HY-N0351A

cis-p-Coumaric acid cis-4-hydroxycinnamic acid	Arachis hypogaea L. Leguminosae Coumarins Phenylpropanoids Plants Source Classification	Apoptosis
cis-p-Coumaric acid (cis-4-Hydroxycinnamic acid) is the cis-form of p-Coumaric acid (HY-N0351), which is higher in viable seeds of groundnuts than in non-viable ones. p-Coumaric acid is an isomer of cinnamic acid with oral activity. p-Coumaric acid inhibits cell proliferation and promotes Apoptosis .

HY-N12267

N,N′-Diferuloylputrescine (E/Z)-Terrestribisamide	Zea mays L. Gramineae Phenols Polyphenols Plants Source Classification	Melanocortin Receptor
N,N′-Diferuloylputrescine ((E/Z)-Terrestribisamide) is a inhibitor of pigmentation with 57% reduction. N,N′-Diferuloylputrescine significantly reduces the protein level of MITF. N,N′-Diferuloylputrescine has strong antioxidant activities as radical scavengers against reactive oxygen species .

HY-N3265

Methyl sinapate MSA	Monophenols Microorganisms Phenols Source Classification	Others
Methyl sinapate (MSA), a hydroxycinnamic acid, is a natural UV screening agent .

HY-W012531R

*2-Hydroxycinnamic* acid (Standard)**	Structural Classification Monophenols Cinnamomum cassia (L.) D. Don Simple Phenylpropanols Phenols Phenylpropanoids Plants Lauraceae Source Classification	Reference Standards HIV SARS-CoV Endogenous Metabolite Bacterial
2-Hydroxycinnamic acid (Standard) is the analytical standard of 2-Hydroxycinnamic acid. This product is intended for research and analytical applications. 2-Hydroxycinnamic acid is a phenolic acid with antimicrobial and antioxidant properties. 2-Hydroxycinnamic acid has antimicrobial activity against *Staphylococcus aureus* and is not susceptible to drug resistance. 2-Hydroxycinnamic acid shows inhibitory effects on infection of HIV/SARS-CoV S pseudovirus with an IC₅₀ of 0.3 mM. In addition, 2-Hydroxycinnamic acid has neuroprotective and antitumor activity .

HY-N12216

Cyanidin 3-sophoroside-5-glucoside	Structural Classification Anthocyans Flavonoids Plants Convolvulaceae Ipomoea batatas (Linn.) Lamarck Source Classification	Others
Cyanidin 3-sophoroside-5-glucoside is the main anthocyanin in purple-fleshed sweet potato and affects the antioxidant activity of purple-fleshed sweet potato .

HY-N12506

Cimicifugic acid F	Ketones, Aldehydes, Acids Ranunculaceae Phenols Polyphenols Plants Cimicifuga racemosa (L.) Nutt. Source Classification	Others
Cimicifugic acid F is a hydroxycinnamic acid ester of piscidic acid isolated from the rhizomes of Cimicifuga racemosa.

HY-N2391R

*p-Hydroxycinnamic* acid (Standard)**	Structural Classification Monophenols Ketones, Aldehydes, Acids Phenols Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite Prostaglandin Receptor
p-Hydroxycinnamic acid, a common dietary phenol, could inhibit platelet activity, with IC50s of 371 μM, 126 μM for thromboxane B2 production and lipopolysaccharide-induced prostaglandin E2 generation, respectively.

HY-N0025

Jionoside D	Phenols Polyphenols Scrophulariaceae Plants Rehmannia glutinosa (Gaert.) Libosch. ex Fisch. et Mey Source Classification	Reactive Oxygen Species (ROS) Apoptosis
Jionoside D is a hydroxycinnamic acid ester with antioxidant property. Jionoside D has scavenging activity of intracellular reactive oxygen species (ROS) and of DPPH radical, and lipid peroxidation inhibitory activity. Jionoside D reduces the apoptotic cells induced by H₂O₂ in V79-4 cells. Jionoside D increases the activities of cellular antioxidant enzymes, SOD and catalase .

HY-N7127R

(E)-m-Coumaric acid (Standard)	Monophenols Ketones, Aldehydes, Acids Phenols Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite
(E)-m-Coumaric acid (Standard) is the analytical standard of (E)-m-Coumaric acid. This product is intended for research and analytical applications. (E)-m-Coumaric acid (3-Hydroxycinnamic acid) is an aromatic acid that highly abundant in food. (E)-m-Coumaric acid (3-Hydroxycinnamic acid) is an antioxidant.

HY-N7929R

5-Feruloylquinic acid (Standard)	Structural Classification Monophenols other families Ketones, Aldehydes, Acids Other Phenylpropanoids Phenols Phenylpropanoids Plants Source Classification	Reference Standards Tyrosinase
5-Feruloylquinic acid (Standard) is the analytical standard of 5-Feruloylquinic acid (HY-N7929). This product is intended for research and analytical applications. 5-Feruloylquinic acid (5-FQA) is a hydroxycinnamic acid derivative. 5-Feruloylquinic acid can be isolated from green coffee beans. 5-Feruloylquinic acid inhibits tyrosinase activity. 5-Feruloylquinic acid has antioxidant properties. 5-Feruloylquinic acid has anticancer activity against lymphoma, oral epidermal cancer, and breast cancer .

HY-N12302A

(E/Z)-Scotanamine D (E/Z)-N1-Dihydrocaffeoyl, N10-caffeoyl spermidine	Structural Classification Alkaloids Other Alkaloids Anisodus tanguticus (Maxinowicz) Pascher Solanaceae Plants Source Classification	Drug Derivative
(E/Z)-Scotanamine D is a hydroxycinnamic acid amide found in the roots of Scopolia tangutica. (E/Z)-Scotanamine D is inactive against μ-, δ-, and κ-opioid receptors .

HY-N17535

Caffeoyltartaric acid	Structural Classification Monophenols Lactuca sativa var. capitata DC. Asteraceae Phenols Plants Asparagaceae Juss. Agave lechuguilla Torr. Source Classification	Others
Caffeoyltartaric acid is an allelochemical. Caffeoyltartaric acid can be isolated from the residues of Agave lechuguilla. Caffeoyltartaric acid exhibits allelopathic activity .

HY-N18287

Tenuifoliose Q	Structural Classification Monophenols Polygalaceae Phenols Plants Polygala tenuifolia Willd. Source Classification	Drug Derivative
Tenuifoliose Q is an oligosaccharide ester esterified with acetic acid, benzoic acid and p-hydroxycinnamic acid, which can be isolated from the root bark of Polygala tenuifolia Willd .

HY-N17762

p-Coumaroyl-N-tryptophan	Structural Classification Alkaloids Other Alkaloids Rubiaceae Plants Coffea arabica L. Source Classification	Others
p-Coumaroyl-N-tryptophan is a hydroxycinnamic acid amide compound that can be isolated from coffee beans (Coffea arabica, Coffea canephora, Coffea liberica). p-Coumaroyl-N-tryptophan can be used to differentiate Robusta coffee from other coffee varieties.

HY-W726472

N-(E-4-Coumaroyl)-aspartate	Structural Classification Monophenols Arabidopsis thaliana (L.) Heynh. Phenols Plants Brassicaceae Source Classification	Endogenous Metabolite
N-(E-4-Coumaroyl)-aspartate is a hydroxycinnamic acid amide compound that can be isolated from Arabidopsis thaliana cell suspension cultures. N-(E-4-Coumaroyl)-aspartate may be involved in metabolic processes related to specific metabolites found in Arabidopsis thaliana cell cultures.

Cat. No.	Product Name	Chemical Structure

HY-N0351S1

p-Coumaric acid-d6 1 Publications Verification
p-Coumaric acid-d₆ is the deuterium labeled p-Coumaric acid (HY-N0351). p-Coumaric acid is the abundant isomer of cinnamic acid which has antitumor and anti-mutagenic activities .

HY-W012531S2

2-Hydroxycinnamic acid-d4

2-Hydroxycinnamic acid-d₄ is deuterium labeled 2-Hydroxycinnamic acid. 2-Hydroxycinnamic acid is a phenolic acid with antimicrobial and antioxidant properties. 2-Hydroxycinnamic acid has antimicrobial activity against Staphylococcus aureus and is not susceptible to drug resistance. 2-Hydroxycinnamic acid shows inhibitory effects on infection of HIV/SARS-CoV S pseudovirus with an IC₅₀ of 0.3 mM. In addition, 2-Hydroxycinnamic acid has neuroprotective and antitumor activity .

HY-107641S

α-Cyano-4-hydroxycinnamic acid-d4

α-Cyano-4-hydroxycinnamic acid-d₄ (α-Cyano-4-hydroxycinnamate-d₄) is the deuterium labeled α-Cyano-4-hydroxycinnamic acid (HY-107641). α-Cyano-4-hydroxycinnamic acid (α-Cyano-4-hydroxycinnamate) is a potent and non-competitive inhibitor of monocarboxylate transporters (MCTs). α-Cyano-4-hydroxycinnamic acid inhibits mitochondrial pyruvate transporter with a K_i of 6.3 μM. α-Cyano-4-hydroxycinnamic acid is used as a matrix to facilitate peptide ionization in matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry applications .

Inquiry Online

Your information is safe with us. * Required Fields.

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社重松貿易株式会社
Salutation			Country or Region *
Applicant Name *			Organization Name *
Department *
Email Address *			Product Name *
Cat. No.			Requested quantity *
Phone Number *
Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent:

hydroxycinnamic acid

Inhibitors & Agonists

NaturalProducts

Isotope-Labeled Compounds

Natural
Products