34 Results for "

hydroxycinnamic acid

" in MedChemExpress (MCE) Product Catalog:
Products (34)

34 Results for "hydroxycinnamic acid" in MCE Product Catalog:

14
14 Publications Verification
Cat. No.: HY-107641
CAS No.: 28166-41-8
Purity:  99.92%
Synonyms: α-Cyano-4-hydroxycinnamate
Research Areas:  

Metabolic Disease

α-Cyano-4-hydroxycinnamic acid (α-Cyano-4-hydroxycinnamate) is a potent and non-competitive inhibitor of monocarboxylate transporters (MCTs). α-Cyano-4-hydroxycinnamic acid inhibits mitochondrial pyruvate transporter with a Ki of 6.3 μM. α-Cyano-4-hydroxycinnamic acid is used as a matrix to facilitate peptide ionization in matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry applications .
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5
5 Cited Publications
Cat. No.: HY-N0351
CAS No.: 501-98-4
Synonyms: trans-4-hydroxycinnamic acid
p-Coumaric acid (trans-4-Hydroxycinnamic acid) is an isomer of cinnamic acid with oral activity. p-Coumaric acid inhibits cell proliferation and promotes apoptosis. p-Coumaric acid has antibacterial, anti-inflammatory, antioxidant and anti-tumor activities .
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2
2 Cited Publications
Cat. No.: HY-W012531
CAS No.: 614-60-8
2-Hydroxycinnamic acid is a phenolic acid with antimicrobial and antioxidant properties. 2-Hydroxycinnamic acid has antimicrobial activity against Staphylococcus aureus and is not susceptible to drug resistance. 2-Hydroxycinnamic acid shows inhibitory effects on infection of HIV/SARS-CoV S pseudovirus with an IC50 of 0.3 mM. In addition, 2-Hydroxycinnamic acid has neuroprotective and antitumor activity .
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1
1 Cited Publications
Cat. No.: HY-N0351S1
CAS No.: 2708298-33-1
Synonyms: trans-4-hydroxycinnamic acid-d6
p-Coumaric acid-d6 is the deuterium labeled p-Coumaric acid (HY-N0351). p-Coumaric acid is the abundant isomer of cinnamic acid which has antitumor and anti-mutagenic activities .
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1
1 Cited Publications
Cat. No.: HY-N7127
CAS No.: 14755-02-3
Synonyms: trans-3-hydroxycinnamic acid
(E)-m-Coumaric acid (trans-3-Hydroxycinnamic acid) is a natural phenolic cinnamic acid derivative with antioxidant activity, and it is found in the young shoots of Limonium densiflorum. (E)-m-Coumaric acid upregulates the levels of SOD and GSH and reduces MDA levels, thereby alleviating oxidative stress and lipid peroxidation in liver tissue. (E)-m-Coumaric acid can be used in studies related to oxidative stress-mediated liver injury .
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Cat. No.: HY-133068
CAS No.: 1782-55-4
Purity:  99.80%
5-Hydroxyferulic acid is a hydroxycinnamic acid and is a metabolite of the phenylpropanoid pathway. 5-Hydroxyferulic acid is a precursor in the biosynthesis of sinapic acid and is also a COMT non-esterifed substrate .
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Cat. No.: HY-N2391
CAS No.: 7400-08-0
p-Hydroxycinnamic acid, a common dietary phenol, could inhibit platelet activity, with IC50s of 371 μM, 126 μM for thromboxane B2 production and lipopolysaccharide-induced prostaglandin E2 generation, respectively.
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Cat. No.: HY-N2232
CAS No.: 66648-44-0
Synonyms: N-trans-Feruloyloctopamine
N-trans-feruloyloctopamine is a natural hydroxycinnamic acid amide compound derived from garlic outer skin, possessing tyrosinase inhibition, FGF2 inhibition, anti-melanogenic, and anti-tumor activities. N-trans-feruloyloctopamine inhibits tyrosinase activity and downregulates tyrosinase mRNA and protein expression (IC50 = 5.3 μM), and inhibits melanogenesis in α-MSH-stimulated B16F10 cells . N-trans-feruloyloctopamine inhibits Akt and p38 MAPK phosphorylation, binds to E-cadherin to block EMT, reduces Slug, inhibits hepatocellular carcinoma invasion, and induces hepatocellular carcinoma cell apoptosis. N-trans-feruloyloctopamine can be used in research related to hepatocellular carcinoma, pigmentation disorders, and UVB-induced skin damage .
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Cat. No.: HY-N3266
CAS No.: 99353-00-1
Methyl rosmarinate is an orally active hydroxycinnamic acid. Methyl rosmarinate exhibits an IC50 of 24.70 μM and a Ki of 15.29 μM against PTP1B, an IC50 of 41.46 μg/mL against BChE, a Ki of 0.61 mM against mushroom tyrosinase, and an IC50 of 2.50 μM against SARS-CoV-2 3CLpro. Methyl rosmarinate downregulates the phosphorylation levels of ERK, JNK, p38, Smad2 and Smad3. Methyl rosmarinate activates erythrocyte BPGM and promotes the production of 2,3-BPG. Methyl rosmarinate induces apoptosis of fibroblasts. Methyl rosmarinate prolongs the survival time of hypoxic mice. Methyl rosmarinate improves insulin sensitivity. Methyl rosmarinate binds to SARS-CoV-2 3CLpro and inhibits viral replication. Methyl rosmarinate induces glioblastoma cell death. Methyl rosmarinate activates the TGR5/AMPK axis and reduces the levels of ROS and MDA. Methyl rosmarinate shows inhibitory activity against MMP-1. Methyl rosmarinate can be used in research related to pulmonary fibrosis, hypoxia-induced injury, type 2 diabetes, Alzheimer's disease, hyperpigmentation disorders, COVID-19, glioblastoma and myocardial ischemia-reperfusion injury .
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Cat. No.: HY-N0351R
CAS No.: 501-98-4
Synonyms: trans-4-hydroxycinnamic acid (Standard)
p-Coumaric acid (Standard) is the analytical standard of p-Coumaric acid. This product is intended for research and analytical applications. p-Coumaric acid (trans-4-Hydroxycinnamic acid) is an isomer of cinnamic acid with oral activity. p-Coumaric acid inhibits cell proliferation and promotes apoptosis. p-Coumaric acid has antibacterial, anti-inflammatory, antioxidant and anti-tumor activities .
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Cat. No.: HY-N7929
CAS No.: 40242-06-6
5-Feruloylquinic acid (5-FQA) is a hydroxycinnamic acid derivative. 5-Feruloylquinic acid can be isolated from green coffee beans. 5-Feruloylquinic acid inhibits tyrosinase activity. 5-Feruloylquinic acid has antioxidant properties. 5-Feruloylquinic acid has anticancer activity against lymphoma, oral epidermal cancer, and breast cancer .
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Cat. No.: HY-118824A
CAS No.: 68573-23-9
Purity:  99.93%
Synonyms: (E/Z)-Moschamine
N-Feruloylserotonin ((E/Z)-Moschamine) is a serotonin hydroxycinnamic acid amide. It can be isolated from a variety of plants, particularly the seeds of safflower (Carthamus tinctorius L.). N-Feruloylserotonin inhibits KCl- and 5-HT-induced elevation of intracellular [Ca 2+]i. It suppresses PDGF-BB-induced phosphorylation of PDGFRβ and ERK1/2. N-Feruloylserotonin exerts anti-inflammatory effects on aortic endothelial cells. It inhibits atherosclerotic plaque formation in apolipoprotein E-deficient mice .
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Cat. No.: HY-E70115
CAS No.: 134712-49-5
Target:  

Fungal Bacterial

Research Areas:  

Infection

Feruloyl esterase is a subclass of carboxylesterases that hydrolyzes the ester linkages between hydroxycinnamic acids and arabinoxylan/pectin polysaccharides in plant cell walls. Feruloyl esterase can hydrolyze ethyl ferulate to release ferulic acid, disrupt plant cell wall structure, promote fiber swelling, and facilitate cellulase hydrolysis. Feruloyl esterase synergizes with xylanase by removing ferulic acid side chains, thereby promoting efficient hydrolysis of xylan into monomers. Feruloyl esterase acts as a virulence factor for Verticillium dahliae VdFAE and Magnaporthe oryzae Fae1, facilitating host infection and colonization. Feruloyl esterase promotes the degradation of cotton GhDFR through binding to its NADPH domain, thereby inhibiting flavonoid-mediated innate immunity and inducing cell death in Nicotiana benthamiana. Feruloyl esterase can be used in studies related to verticillium wilt and rice blast .
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Cat. No.: HY-N0351A
CAS No.: 4501-31-9
Synonyms: cis-4-hydroxycinnamic acid
cis-p-Coumaric acid (cis-4-Hydroxycinnamic acid) is the cis-form of p-Coumaric acid (HY-N0351), which is higher in viable seeds of groundnuts than in non-viable ones. p-Coumaric acid is an isomer of cinnamic acid with oral activity. p-Coumaric acid inhibits cell proliferation and promotes Apoptosis .
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Cat. No.: HY-N3265
CAS No.: 20733-94-2
Synonyms: MSA
Methyl sinapate (MSA), a hydroxycinnamic acid, is a natural UV screening agent .
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Cat. No.: HY-W012531R
CAS No.: 614-60-8
2-Hydroxycinnamic acid (Standard) is the analytical standard of 2-Hydroxycinnamic acid. This product is intended for research and analytical applications. 2-Hydroxycinnamic acid is a phenolic acid with antimicrobial and antioxidant properties. 2-Hydroxycinnamic acid has antimicrobial activity against Staphylococcus aureus and is not susceptible to drug resistance. 2-Hydroxycinnamic acid shows inhibitory effects on infection of HIV/SARS-CoV S pseudovirus with an IC50 of 0.3 mM. In addition, 2-Hydroxycinnamic acid has neuroprotective and antitumor activity .
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Cat. No.: HY-133068A
CAS No.: 110642-42-7
Target:  

COMT

Research Areas:  

Metabolic Disease

(E)-5-Hydroxyferulic acid is the E-isomer of 5-Hydroxyferulic acid (HY-133068). 5-hydroxyferulic acid is a hydroxycinnamic acid and is a metabolite of the phenylpropanoid pathway. 5-Hydroxyferulic acid is a precursor in the biosynthesis of sinapic acid and is also a COMT non-esterifed substrat .
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Cat. No.: HY-121231R
CAS No.: 501-16-6
trans-Caffeic acid (Standard) is the analytical standard of trans-Caffeic acid (HY-121231). This product is intended for research and analytical applications. trans-Caffeic acid is a hydroxycinnamic acid widely distributed in coffee, propolis, and Lamiaceae herbs. trans-Caffeic acid exhibits significant antioxidant and photoprotective activities, and can be used in cancer-related research. trans-Caffeic acid readily undergoes reversible isomerization to form its cis-isomer in protic solvents, under high temperature, ultraviolet radiation, and stress conditions. Binding of trans-Caffeic acid with aluminum, lead, or copper ions attenuates isomerization and inhibits the formation of vinylcatechol, while complexation with lead or copper ions also promotes the formation of aesculetin .
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Cat. No.: HY-W012531S2
2-Hydroxycinnamic acid-d4 is deuterium labeled 2-Hydroxycinnamic acid. 2-Hydroxycinnamic acid is a phenolic acid with antimicrobial and antioxidant properties. 2-Hydroxycinnamic acid has antimicrobial activity against Staphylococcus aureus and is not susceptible to drug resistance. 2-Hydroxycinnamic acid shows inhibitory effects on infection of HIV/SARS-CoV S pseudovirus with an IC50 of 0.3 mM. In addition, 2-Hydroxycinnamic acid has neuroprotective and antitumor activity .
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Cat. No.: HY-N7127R
CAS No.: 14755-02-3
Synonyms: trans-3-hydroxycinnamic acid (Standard)
(E)-m-Coumaric acid (Standard) (trans-3-Hydroxycinnamic acid (Standard)) is the analytical standard of (E)-m-Coumaric acid (HY-N7127). This product is intended for research and analytical applications. (E)-m-Coumaric acid (trans-3-Hydroxycinnamic acid) is a natural phenolic cinnamic acid derivative with antioxidant activity, and it is found in the young shoots of Limonium densiflorum. (E)-m-Coumaric acid upregulates the levels of SOD and GSH and reduces MDA levels, thereby alleviating oxidative stress and lipid peroxidation in liver tissue. (E)-m-Coumaric acid can be used in studies related to oxidative stress-mediated liver injury .
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