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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
113 Results for "
immobilization
" in MedChemExpress (MCE) Product Catalog:
Products (113)
113 Results for "immobilization" in MCE Product Catalog:
29
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Tricaine methanesulfonate (MS-222) is common used to immobilize fish for marking or transport and to suppress sensory systems during invasive procedures .
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7 Cited Publications
Cat. No.: HY-18102
CAS No.: 1215085-92-9
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GLPG0492 is an orally active, non-steroidal selective androgen receptor modulator. GLPG0492 exerts functional transactivation by binding to the ligand-binding domain of the receptor, exhibiting preferential partial agonist activity in muscle and bone tissues with low activity in reproductive tissues. GLPG0492 effectively counteracts muscle atrophy-related pathways, significantly enhances muscle strength, maintains motor ability, reduces fibrosis and improves electrophysiological parameters. GLPG0492 prevents immobilization-induced muscle atrophy and regulates muscle mass homeostasis, serving as a valuable tool compound for studies on Duchenne muscular dystrophy, muscle loss and various types of disuse musculoskeletal atrophy .
2
2 Cited Publications
Synonyms: γ-Aminopropyltriethoxysilane; APTES
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Cholesterol oxidase, Microorganism (ChOx, Microorganism) (EC 1.1.3.6) is a cholesterol oxidase identified from bacterial sources. Cholesterol oxidase, Microorganism catalyzes the oxidation of cholesterol to 4-cholesten-3-one, while simultaneously reducing oxygen to hydrogen peroxide. Cholesterol oxidase, Microorganism retains its enzymatic activity and exhibits improved catalytic efficiency upon immobilization. Cholesterol oxidase, Microorganism is applicable for cholesterol detection, steroid biotransformation, and research on tuberculosis-related diseases .
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2 Cited Publications
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KF38789 is a selective inhibitor of P-selectin-PSGL-1 binding. KF38789 inhibits the binding of U937 cells to immobilized P-selectin immunoglobulin G chimeric protein (P-selectin-Ig) with an IC50 value of 1.97 μM .
1
1 Cited Publications
Cat. No.: HY-W013151
CAS No.: 114932-60-4
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1-Pyrenebutyric acid N-hydroxysuccinimide ester (PANHS) is a linker and interface coupling agent that can be used to prepare electrochemical biosensors. 1-Pyrenebutyric acid N-hydroxysuccinimide ester immobilizes SARS-CoV-2 spike antibodies on graphene sheets. 1-Pyrenebutyric acid N-hydroxysuccinimide ester is often used as an activation reagent for carboxylic acids in organic chemistry or biochemistry .
1
1 Cited Publications
Cat. No.: HY-W015591
CAS No.: 90-64-2
Synonyms: (±)-Mandelic acid; DL-Mandelic acid
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1
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Cross-linked dextran G 25 is a cross-linked dextran gel chromatography medium that possesses multiple separation activities, including molecular sieve effects, weak anion exchange, and aromatic adsorption. Cross-linked dextran G 25 weakly exchanges cations through immobilized terminal carboxyl groups and repels anions at low ionic strength. Cross-linked dextran G 25 is used for the fractionation of low molecular weight solutes, including peptides, amino acids, nucleotide sugar derivatives, and aromatic compounds .
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(R)-Nimodipine ((R)-BAY-e 9736) is an orally active, blood-brain barrier-permeable L-type calcium channel blocker with an IC50 of 5 nM. (R)-Nimodipine inhibits corticosterone release by blocking calcium channels on the hypothalamic-pituitary-adrenal axis, thereby reversing immobilization stress-induced memory impairment and behavioral abnormalities. (R)-Nimodipine is widely used in studies related to aneurysmal subarachnoid hemorrhage, cerebral ischemia, epilepsy, age-related degenerative neurological diseases, and alcohol intoxication .
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Creatine Kinase MB (rCK-MB), Recombinant Human (CK-MB) is a cytoplasmic creatine kinase isoenzyme composed of M and B subunits, belonging to the phosphotransferase family. Creatine Kinase MB (rCK-MB), Recombinant Human catalyzes the transfer of phosphate groups between creatine and phosphocreatine, and consumes phosphocreatine immobilized on the surface of the biosensor, resulting in a decrease in the electrochemical peak current that is proportional to its concentration. Creatine Kinase MB (rCK-MB), Recombinant Human can be used in studies of acute myocardial infarction, coronary artery disease with atherosclerotic plaques, autoimmune myocarditis, and malignant tumors .
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1 Cited Publications
Cat. No.: HY-E70365A
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IdeS (Immobilized, Microspin) is a resin that covalently couples IdeS protease to agarose beads and cleaves IgG at specific sites to generate F(ab')2 and Fc fragments. After IdeS (Immobilized, Microspin) digestion, F(ab')2 and Fc fragments are obtained in the solution without IdeS enzyme.
1
1 Cited Publications
Cat. No.: HY-19639
CAS No.: 858102-78-0
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E-982 is a steroid used for the on-line screening of the DNA unwinding element binding protein (DUE-B) immobilized protein column .
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1 Cited Publications
Cat. No.: HY-W591424
CAS No.: 92451-01-9
Synonyms: mPEG2000-SC; mPEG2000-Succinimidyl ester
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1 Cited Publications
Cat. No.: HY-P990203
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Lipase,Candida antarctica (Immobilized) is an immobilized lipase isolated from Candida antarctica fraction B. Lipase,Candida antarctica (Immobilized) features high stability and selectivity. Lipase,Candida antarctica (Immobilized) is widely used in fields such as chemical synthesis, food oil modification, and biodiesel production .
FP-biotin is a potent organophosphorus toxicant, well-suited for searching for new biomarkers of organophosphorus toxicants exposure. FP-Biotin quantifies FAAH, ABHD6, and MAG-lipase activity. FP-biotin is used for studies with plasma because biotinylated peptides are readily purified by binding to immobilized avidin beads .
Synonyms: 3'-Azido-3'-deoxythymidine β-D-glucuronide sodium
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Zidovudine O-β-D-glucuronide (3'-Azido-3'-deoxythymidine β-D-glucuronide) sodium is the glucuronide conjugate and metabolite of Zidovudine (HY-17413), which can be used to detect UGT2B7 activity. As a substrate, Zidovudine O-β-D-glucuronide sodium undergoes deconjugation via hydrolysis by immobilized β-glucuronidase to produce Zidovudine .
Cat. No.: HY-D0031
CAS No.: 196504-57-1
Synonyms: APTS
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8-Aminopyrene-1,3,6-trisulfonic acid trisodium (APTS) is an anionic fluorescent dye (excitation/emission: 425/503 nm in pH 7.4 PBS). The fluorescence intensity of 8-Aminopyrene-1,3,6-trisulfonic acid trisodium remains stable at pH 4-10. 8-Aminopyrene-1,3,6-trisulfonic acid trisodium retains its fluorescence properties when immobilized in a hydrogel by copolymerization. 8-Aminopyrene-1,3,6-trisulfonic acid trisodium can be used for glucose sensing .
Cat. No.: HY-E70313
Synonyms: Candida antarctica lipase B
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Lipase,Candida antarctica (Immobilized on hydrophilic carrier) (Candida antarctica lipase B) is a lipase derived from Candida antarctica and immobilized on a hydrophilic carrier. Lipase,Candida antarctica (Immobilized on hydrophilic carrier) is a green catalyst that can be used to catalyze polymer synthesis .
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Penicillin amidase, E. coli (Immobilized) (PGA) is an amidohydrolase commonly used in industrial biocatalysis. Penicillin amidase, E. coli (Immobilized) serves as a starting material in the synthesis of semi-synthetic penicillins. Penicillin amidase, E. coli (Immobilized) promotes the production of semi-synthetic β-lactam antibiotics, participates in peptide synthesis, and catalyzes the formation of chiral compounds. Penicillin amidase, E. coli (Immobilized) is regulated by temperature and phenylacetic acid in E. coli. In free E. coli, it participates in the assimilation of aromatic compounds as a carbon source. Penicillin amidase, E. coli (Immobilized) is hypothesized to act as a scavenging enzyme for phenylacetyl-containing compounds in microbial metabolism and is associated with bacterial quorum sensing .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
