85 Results for "

immunization

" in MedChemExpress (MCE) Product Catalog:
Products (85)

85 Results for "immunization" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-P99156
CAS No.: 1673516-98-7
Synonyms: BMS-986016

Target:  

LAG-3

Research Areas:  

Cancer

Relatlimab (BMS-986016) is a human monoclonal antibody anti-LAG-3 antibody generated by immunization of transgenic mice bearing human immunoglobulin miniloci with recombinant LAG-3 protein. Relatlimab blocks LAG-3/MHC II interaction with an IC50 value of 0.67 nM and LAG-3/FGL1 interaction with an IC50 value of 0.019 nM. Relatlimab can be used in research of cancer .
loading...
    loading...
3
3 Cited Publications
Cat. No.: HY-12964
CAS No.: 1239875-86-5
Purity:  99.32%
Target:  

TAM Receptor

Research Areas:  

Cancer

SGI-7079 is a selective, ATP-competitive, orally active inhibitor of the receptor tyrosine kinase Axl. SGI-7079 blocks Axl-mediated signaling pathways such as NF-κB activation and MMP-9 expression, thereby inhibiting tumor cell proliferation, migration and invasion. SGI-7079 is mainly used in the research of malignant tumors such as inflammatory breast cancer and bladder cancer, as well as in combination with immunization (used in combination with PD-1 therapy)[1][2][3].
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-128679
CAS No.: 1893397-65-3
Purity:  99.92%
Target:  

IKK

Research Areas:  

Cancer

TBK1/IKKε-IN-5 (compound 1) is an orally active TBK1 and IKKε dual inhibitor, with IC50 values of 1 and 5.6 nM, respectively. TBK1/IKKε-IN-5 enhances the blockade response to PD-1 and induces immune memory in rats when combines with anti-PD-L1. TBK1/IKKε-IN-5 can be used in cancer research, especially in tumour immunity .
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-N3522
CAS No.: 237068-41-6
Platycoside E is a platycodigenin-type saponin isolated from the root of Platycodon grandiflorum with haemolytic activity and adjuvant potential. Platycoside E promotes the production of the sera OVA-specific IgG2a and IgG2b antibody in the ovalbumin (OVA)-immunized mice .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-NP101
Synonyms: Bovine Type I collagen, immunization grade
Highly purified Type I collagen, from bovine skin (Bovine Type I collagen, immunization grade) plays an important role in the structure and function of skin, bone, tendons, and many others. Type I collagen potently stimulates angiogenesis in vitro and in vivo. Highly purified Type I collagen, from bovine skin is an immunization grade that can be used for immunization to generate antibodies .
loading...
    loading...
Cat. No.: HY-130320
CAS No.: 1246298-63-4
Purity:  98.17%
Synonyms: Glucopyranosyl lipid A
Research Areas:  

Inflammation/Immunology Cancer

Monophosphoryl lipid A (Glucopyranosyl lipid A) is a toll-like receptor 4 agonist. Monophosphoryl lipid A is derived from the cell wall of nonpathogenic Salmonella. Monophosphoryl lipid A can be used for the research of immunization and vaccine .
loading...
    loading...
Cat. No.: HY-143320
CAS No.: 2816929-47-0
Purity:  96.08%
Target:  

STING

Research Areas:  

Cancer

STING agonist-17 (compound 4a) is a potent STING agonist with an IC50 value of 0.062 nM. STING agonist-17 has anti-cancer activity for tumor immunization .
loading...
    loading...
Cat. No.: HY-P99791
CAS No.: 2066544-85-0
Synonyms: SYNT001; ALXN1830

Target:  

Inhibitory Antibodies

Research Areas:  

Inflammation/Immunology

Orilanolimab (SYNT001) is a humanized, de-immunized and FcRn-blocking monoclonal antibody. Orilanolimab blocks the interaction between FcRn and the Fc portion of IgG molecules. Orilanolimab impedes IgG IC activation of the FcRn-mediated adaptive immune function. And Orilanolimab disrupts the associated pathways related to IgG homeostasis and innate and adaptive immunity .
loading...
    loading...
Cat. No.: HY-NP109
Synonyms: Mouse Type I collagen, immunization grade
Highly purified type I collagen, from mouse skin (Mouse Type I collagen, immunization grade) is an immune grade collagen derived from mouse skin, which can stimulate the animal's immune system to produce specific antibodies against this collagen. Collagen is also a substrate for hydrolysis by MMPs .
loading...
    loading...
Cat. No.: HY-NP113
Synonyms: Chick Type II collagen, immunization grade
Highly purified Type II collagen, from chick sternal cartilage (Chick Type II collagen, immunization grade) is an immune grade collagen derived from chick sternal cartilage, which can stimulate the animal's immune system to produce specific antibodies against this collagen. Collagen is also a substrate for hydrolysis by MMPs .
loading...
    loading...
Cat. No.: HY-159067
CAS No.: 9064-91-9
Synonyms: DEAE-dextran, MW 500000 hydrochloride, from bacterial (Leuconostoc mesenteroides); Diethylaminoethyl-dextran, MW 500000 hydrochloride
DEAE-dextran, MW 500000 hydrochloride (DEAE-dextran, MW 500000 hydrochloride, from bacterial (Leuconostoc mesenteroides)) is a high-molecular-weight positively charged polymer that significantly enhances the uptake of viral RNA by tissue culture cells. When employed in the delivery system for "tumor immunity" RNA-splenocyte transfer, DEAE-dextran can markedly extend the lifespan of tumor-bearing animals, comparable to that of actively immunized animals. Furthermore, DEAE-dextran serves as a complexing agent for nucleic acids, forming composite particles with DNA/RNA for extensive applications in gene delivery. Additionally, DEAE-dextran can be utilized as a coating for liposomes .
loading...
    loading...
Cat. No.: HY-NP126
Synonyms: Porcine Type XI collagen, immunization grade
Highly purified Type XI collagen, from porcine articular cartilage (Porcine Type XI collagen, immunization grade) is an immune grade collagen derived from porcine articular cartilage, which can stimulate the animal's immune system to produce specific antibodies against this collagen. Collagen is also a substrate for hydrolysis by MMPs .
loading...
    loading...
Cat. No.: HY-P4152
CAS No.: 1431550-68-3
Target:  

Peptides

Research Areas:  

Inflammation/Immunology Cancer

Etimumotide is an immunological agent for active immunization, as well as an antineoplastic agent .
loading...
    loading...
Cat. No.: HY-NP102
Synonyms: Bovine Type II collagen, immunization grade
Highly purified Type II collagen, from bovine articular cartilage (Bovine Type II collagen, immunization grade), an immunization grade, is the major matrix protein in cartilage that can be used for the study of arthritis .
loading...
    loading...
Cat. No.: HY-159670
CAS No.: 1332714-01-8
Synonyms: MPLA-12
Category:  

Lipids

Monophosphoryl Lipid A-12 (MPLA-12) is a Toll-like receptor 4 agonist. Monophosphoryl Lipid A-12 can be used for the research of immunization and vaccine .
loading...
    loading...
Cat. No.: HY-N8228
CAS No.: 2306139-04-6
17-Hydroxyneomatrine, extracted from Sophora flavescens, can well inhibit the growth of human cervical carcinoma Hela cells, has the wide-range antibacterial, anti-allergy, anti-tumor, anti-arrhythmia, swelling-subsiding diuresis, immunizing, and biological regulation functions .
loading...
    loading...
Cat. No.: HY-P5396A
Research Areas:  

Others

GAD65 (524-543) acetate is a biological active peptide with amino acids 524 to 543 fragment of glutamic acid decarboxylase 65 (GAD65). GAD65 (524-543) acetate is one of the first fragments of the islet antigen to induce proliferative T cell responses in the non-obese diabetic (NOD) mouse model of spontaneous autoimmune diabetes. GAD65 (524-543) acetate is a specific, possibly low affinity, stimulus for the spontaneously arising diabetogenic T cell clone BDC2.5. Immunization with GAD65 (524-543) acetate increases the susceptibility of the NOD mice to type 1 diabetes induced by the adoptive transfer of BDC2.5 T cells .
loading...
    loading...
Cat. No.: HY-NP103
Synonyms: Bovine Type III collagen, immunization grade
Highly purified Type III collagen, from bovine skin (Bovine Type III collagen, immunization grade) is an immune grade collagen derived from bovine skin, which can stimulate the animal's immune system to produce specific antibodies against this collagen. Collagen is also a substrate for hydrolysis by MMPs .
loading...
    loading...
Cat. No.: HY-159746
Research Areas:  

Inflammation/Immunology

Carbomer adjuvant (HS801) is an adjuvant composed of carbomer and cationic polymers. This adjuvant is safe, non-toxic, and metabolizable. It can enhance the immune response, increase the antibody titer of each antigen component of the vaccine after immunization, and reduce the number of immunizations required. It is suitable for various veterinary vaccines. It is recommended for use in porcine circovirus, mycoplasma hyopneumoniae, and haemophilus parasuis.
loading...
    loading...
Cat. No.: HY-P2212
CAS No.: 53-73-6
Target:  

Angiotensin Receptor

Research Areas:  

Inflammation/Immunology

Angiotensin amide ((Asn1,Val5)-Angiotensin II) is a potent vasoconstrictor. Angiotensin amide is a derivative of angiotensin II. Angiotensin amide can be used as a cardiac activator .
loading...
    loading...