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internal standard

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Bacterial (1) Biochemical Assay Reagents (1) Bradykinin Receptor (2) Endogenous Metabolite (7) ERK (1) Fluorescent Dye (1) GnRH Receptor (1) Influenza Virus (1) Isotope-Labeled Compounds (10) Nuclear Factor of activated T Cells (NFAT) (1) TRP Channel (1)
By Research Areas:	Cancer (5) Cardiovascular Disease (2) Endocrinology (2) Infection (2) Inflammation/Immunology (3) Metabolic Disease (4)

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W004262

Methyl nonadecanoate

Others Others

Methyl nonadecanoate may be used as an internal standard to determine fatty acid methyl ester (FAME) content of biodiesel .

Methyl nonadecanoate	Others	Others
Methyl nonadecanoate may be used as an internal standard to determine fatty acid methyl ester (FAME) content of biodiesel .

HY-P3751

[Tyr8] Bradykinin	Bradykinin Receptor ERK	Cardiovascular Disease Endocrinology
[Tyr8] Bradykinin is a B₂ kinin receptor agonist. [Tyr8] Bradykinin also stimulates ERK1/2 phosphorylation. [Tyr8] Bradykinin can be used as an internal standard .

HY-112552

1,2-Distearoyl-sn-glycerol DSG; 1,2-Dioctadecanoyl-sn-glycerol	Endogenous Metabolite	Others
1,2-Distearoyl-sn-glycerol (DSG; 1,2-Dioctadecanoyl-sn-glycerol) acts as an internal standard for Separation and identification of molecular species of 1,2-diacyl-sn-glycerol (DAG) .

HY-W725954

Triheneicosanoin	Others	Others
Triheneicosanoin is a triacylglycerol containing heneicosanoic acid groups. Triheneicosanoin can be used as internal standard for the quantification of fatty acids in the milk samples .

HY-113209S

8-Iso-PGF2a-d4 8-iso Prostaglandin F2α-d₄	Isotope-Labeled Compounds	Metabolic Disease
8-Iso-PGF2a-d4 (8-iso Prostaglandin F2α-d4) is an active compound. 8-Iso-PGF2a-d4 can be used the internal standard .

HY-B0870S

Bensulfuron-methyl-d6	Isotope-Labeled Compounds	Others
Bensulfuron-methyl-d₆ is a deuterated Bensulfuron-methyl (HY-B0870) (sulfonylurea pesticides). Bensulfuron-methyl-d₆ can be used as an internal standard for the determination of pesticide residues by LC-MS[1].

HY-111095S1

D-(-)-Lactic acid-13C (R)-2-Hydroxypropionic acid-¹³C; D-Lactic acid-¹³C	Isotope-Labeled Compounds	Others
D-(-)-Lactic acid-13C ((R)-2-Hydroxypropionic acid-13C) is a ¹³C-labeled D-Lactic acid. D-(-)-Lactic acid-13C can be used as an internal standard and can also be used in studies such as metabolic tracing.

HY-B0389A

D-Glucose-13C6 4 Publications Verification Glucose-¹³C₆; D-(+)-Glucose-¹³C₆; Dextrose-¹³C₆	Endogenous Metabolite	Others Metabolic Disease
D-Glucose- ¹³C₆ is a stable isotope-labeled counterpart of D-glucose (HY-B0389). D-Glucose- ¹³C₆ can be used as a metabolic tracer to trace glucose-related synthetic catabolism or as synthesis ingredient, minimal media reagent, and internal standard .

HY-P3750

Methionyl-Lysyl-Bradykinin Met-Lys-Bradykinin	Bradykinin Receptor	Cardiovascular Disease Endocrinology
Methionyl-Lysyl-Bradykinin (Met-Lys-Bradykinin), a Bradykinin (HY-P0206) analogue, is a kinin .

HY-W004154

2-Ethylbutyric acid

Others Others

2-Ethylbutyric acid acts as an internal standard (IS) in a standard addition calibration method for the VFA analysis of faeces .
HY-W004285

Methyl undecanoate

Others Others

Methyl undecanoate is an internal standard in gas-liquid chromatogram .
HY-W016993

2,3,4-Trihydroxybenzoic acid

Others Others

2,3,4-Trihydroxybenzoic acid is an internal standard in separation of phenolic acids by HPLC.
HY-W012606

1,5,5-Trimethylhydantoin

TMH
Others Others

1,5,5-Trimethylhydantoin (TMH) is a non-isotopic internal standard (IS) .
HY-108353S

Isoprenaline-d7 acetate

Isotope-Labeled Compounds Others

Isoprenalin-d7 acetate is an internal standard for the determination of isoproterenol by GC- or LC-MS .

2-Ethylbutyric acid	Others	Others
2-Ethylbutyric acid acts as an internal standard (IS) in a standard addition calibration method for the VFA analysis of faeces .

Methyl undecanoate	Others	Others
Methyl undecanoate is an internal standard in gas-liquid chromatogram .

2,3,4-Trihydroxybenzoic acid	Others	Others
2,3,4-Trihydroxybenzoic acid is an internal standard in separation of phenolic acids by HPLC.

1,5,5-Trimethylhydantoin TMH	Others	Others
1,5,5-Trimethylhydantoin (TMH) is a non-isotopic internal standard (IS) .

Isoprenaline-d7 acetate	Isotope-Labeled Compounds	Others
Isoprenalin-d7 acetate is an internal standard for the determination of isoproterenol by GC- or LC-MS .

HY-131676

C17 Sphingomyelin (d18:1/17:0) SM (d18:1/17:0); Heptadecanoyl Sphingomyelin; N-Heptadecanoyl-D-erythro-Sphingosylphosphorylcholine	Endogenous Metabolite	Metabolic Disease
C17 Sphingomyelin is a synthetic derivative of sphingomyelin that has been used as an internal standard for the quantification of sphingomyelin.

HY-D1674

Sulforhodamine G

Fluorescent Dye Others

Sulforhodamine G is a fluorescent stain with broad dynamic ranges. Sulforhodamine G can be used for the research of protein stains .

Sulforhodamine G	Fluorescent Dye	Others
Sulforhodamine G is a fluorescent stain with broad dynamic ranges. Sulforhodamine G can be used for the research of protein stains .

HY-W004285S

Methyl undecanoate-d21	Isotope-Labeled Compounds
Methyl undecanoate-d₂₁ is the deuterium labeled Methyl undecanoate. Methyl undecanoate is an internal standard in gas-liquid chromatogram[1].

HY-N1393

2-Methoxybenzoic acid NSC 3778; O-Methylsalicylic acid; Salicylic acid methyl ether	Endogenous Metabolite	Cancer
2-Methoxybenzoic acid (NSC 3778) is used as an internal standard of salicylic acid and its putative biosynthetic precursors in cucumber leaves. Another known use is in the synthesis of Benextramine.

HY-W700539S

N1-Acetyl triethylenetetramine-d4	Isotope-Labeled Compounds	Others
N1-Acetyl triethylenetetramine-d4 is deuterated N1-Acetyl triethylenetetramine and can be used as an internal standard in plasma extracts .

HY-N0808R

Camphor (Standard)	TRP Channel Influenza Virus	Infection Inflammation/Immunology Cancer
Camphor (Standard) is the analytical standard of Camphor. This product is intended for research and analytical applications. Camphor ((±)-Camphor) is a topical anti-infective and anti-pruritic and internally as a stimulant and carminative. However, Camphor is poisonous when ingested. Antiviral, antitussive, and anticancer activities . Camphor is a TRPV3 agonist .

HY-14865S

Omadacycline-d9 PTK 0796-d₉; Amadacycline-d₉	Bacterial Isotope-Labeled Compounds	Others
Omadacycline-d9 (PTK 0796-d9; Amadacycline-d9) is the deuterium labeled Omadacycline (HY-14865) that can be used as the internal standard for the analysis of Omadacycline .

HY-131389

Cholesteryl heptadecanoate	Others	Others
Cholesteryl heptadecanoate is a cholesteryl ester internal standard that accurately determines the concentration of free cholesterol in cells without hydrolyzing triglycerides. Cholesteryl heptadecanoate can be used for the quantitative determination of cholesteryl esters by GC or LC mass spectrometry .

HY-N6726S1

Fumonisin B3-13C34-1	Isotope-Labeled Compounds	Others
Fumonisin B3-13C34-1 is the isotopic internal standard of Fumonisin B3 (HY-N6726). Fumonisin B3 is a mycotoxin derived from fusarium fungi, a member of fumonisins .

HY-18569S

3-Indoleacetic acid-d5 1 Publications Verification Indole-3-acetic acid-d₅; 3-IAA-d₅	Endogenous Metabolite Isotope-Labeled Compounds	Others
3-Indoleacetic acid-d₅ is the deuterium labeled 3-Indoleacetic acid. 3-Indoleacetic acid-d₅ can be used as internal standard for assay of IAA releases by alkaline hydrolysis of ester and amide conjugates[1].

HY-107935

6α-Fluoroprednisolone Fluprednisolone	Others	Inflammation/Immunology
6α-Fluoroprednisolone (Fluprednisolone) is an internal standard for methylprednisolone, prednisolone and prednisone. 6α-Fluoroprednisolone is an anti-inflammatory agent. 6α-Fluoroprednisolone can be used for congenital adrenal virilism and Addison's disease research .

HY-N1393S

2-Methoxybenzoic acid-13C6 NSC 3778-¹³C₆; O-Methylsalicylic acid-¹³C₆; Salicylic acid methyl ether-¹³C₆	Isotope-Labeled Compounds Endogenous Metabolite	Cancer
2-Methoxybenzoic acid- ¹³C₆ is the ¹³C-labeled 2-Methoxybenzoic acid. 2-Methoxybenzoic acid (NSC 3778) is used as an internal standard of salicylic acid and its putative biosynthetic precursors in cucumber leaves. Another known use is in the synthesis of Benextramine.

HY-W019721

Cyclosporin D	Nuclear Factor of activated T Cells (NFAT)	Inflammation/Immunology
Cyclosporin D, a metabolite of Cyclosporin A, is a weak immunosuppressant. Cyclosporin D is used as internal standard for quantification of Cyclosporin A . Cyclosporin A is a potent immunosuppressant agent, suppress T cell activation by inhibiting calcineurin and the calcineurin-dependent transcription factors nuclear factor of activated T cells (NFAc) .

HY-W643167

1,2,3-Tritridecanoylglycerol Glycerol Tritridecanoyl; 13:0 TAG; 13:0/13:0/13:0-TG	Others	Infection
1,2,3-Tritridecanoyl glycerol is a synthetic triacylglycerol that contains tridecanoic acid in the sn-1, sn-2, and sn-3 positions. It has been used as a standard for the relative quantification of triacylglycerols in C. elegans fat stores. It has also been used as an internal standard for the quantification of triacylglycerols in the serum and liver of adult rat offspring receiving dietary conjugated linoleic acids during and after gestation.

HY-141579

Sphingosine (d17:1)	Others	Others
Sphingosine (d17:1) is a 17-carbon sphingosine found in human skin. Sphingosine (d17:1) can be phosphorylated by sphingosine kinases to produce C-17 sphingosine-1-phosphate. Sphingosine C-17 was used as an internal standard for spectral analysis of sphingoid compounds .

HY-W706672

Propane-1,2,3-triyl tritricosanoate Glycerol Tritricosanoate; TG(23:0/23:0/23:0); Tritricosanoin	Endogenous Metabolite	Metabolic Disease
1,2,3-Tritricosanoyl glycerol is a triacylglycerol that contains tricosanoic acid (HY-W009081) at the sn-1, sn-2, and sn-3 positions. It has been used as an internal standard for the quantification of fatty acids in the triglyceride component of human aortic endothelial cells (HAECs) grown in media supplemented with stearic and/or oleic acid.

HY-123023

12(S)-HETE D8	Others	Cancer
12(S)-HETE D8 contains eight deuterium atoms at the 5, 6, 8, 9, 11, 12, 14 and 15 positions. 12(S)-HETE D8 is intended for use as an internal standard for the quantification of 12(S)-HETE by GC- or LC-mass spectrometry (MS). 12(S)-HETE D8 is the predominant lipoxygenase product of mammalian platelets. It enhances tumor cell adhesion to endothelial cells, fibronectin, and the subendothelial matrix at 0.1 µM.

HY-W750595

6-(L-1,2,3-Trihydroxybutyl)-pterin	Others	Cancer
6-(L-1,2,3-Trihydroxybutyl)-pterin is a derivative of L-biopterin (HY-102015) and is the oxidized form of tetrahydro-L-biopterin (BH4) as well as D-biopterin. Co-ingestion of 6-(L-1,2,3-Trihydroxybutyl)-pterin (0.5%) with the carcinogen 4-dimethylaminoazobenzene reduces the incidence of 4-dimethylaminoazobenzene-induced liver tumors in rats. 6-(L-1,2,3-Trihydroxybutyl)-pterin has been used as an internal standard for the LC-MS quantification of biopterin and neopterin in rat plasma.

HY-P0048

(Des-Gly10,D-Ala6,Pro-NHEt9)-LHRH Surfagon	GnRH Receptor	Others
(Des-Gly10,D-Ala6,Pro-NHEt9)-LHRH (Surfagon, Mwt 1167.34 Da) is an agonist of gonadotropin-releasing hormone (GnRH). (Des-Gly10,D-Ala6,Pro-NHEt9)-LHRH can be used as an internal standard for the LC-MS analysis of leuprorelide acetate. (Des-Gly10,D-Ala6,Pro-NHEt9)-LHRH has potential applications in biochemical analysis and fertility .

HY-W127391

1,2-Dilaurin (Rac)-1,2-Didodecanoylglycerol	Biochemical Assay Reagents	Others
1,2-Dilaurin is a diacylglycerol containing lauric acid at the sn-1 and sn-2 positions. It has been used as an internal standard for the quantification of diglycerides in rat desheathed sciatic nerves. [1] Monomolecular films containing 1,2-dilauroyl-rac-glycerol have been used as substrates to measure surface pressure and the effect of pancreatic procolipase and colipase on porcine pancreatic lipase activity. [2] References: [1]. Zhu, X. and Eichberg, J. 1,2-Diacylglycerol content and its arachidonyl-containing molecular species are reduced in the sciatic nerve of streptozotocin-induced diabetic rats. J. Neurochemistry. 55(3), 1087-1090 (1990).[2]. Wieloch, T., Borgstr m, B., Piéroni, G. et al. Porcine trypsinogen and its trypsin-activated form: lipid binding and lipase activation on monomolecular membranes. FEBS Express. 128(2), 217-220 (1981).

1,2-Dilaurin (Rac)-1,2-Didodecanoylglycerol	Biochemical Assay Reagents
1,2-Dilaurin is a diacylglycerol containing lauric acid at the sn-1 and sn-2 positions. It has been used as an internal standard for the quantification of diglycerides in rat desheathed sciatic nerves. [1] Monomolecular films containing 1,2-dilauroyl-rac-glycerol have been used as substrates to measure surface pressure and the effect of pancreatic procolipase and colipase on porcine pancreatic lipase activity. [2] References: [1]. Zhu, X. and Eichberg, J. 1,2-Diacylglycerol content and its arachidonyl-containing molecular species are reduced in the sciatic nerve of streptozotocin-induced diabetic rats. J. Neurochemistry. 55(3), 1087-1090 (1990).[2]. Wieloch, T., Borgstr m, B., Piéroni, G. et al. Porcine trypsinogen and its trypsin-activated form: lipid binding and lipase activation on monomolecular membranes. FEBS Express. 128(2), 217-220 (1981).

[Tyr8] Bradykinin	Bradykinin Receptor ERK	Cardiovascular Disease Endocrinology
[Tyr8] Bradykinin is a B₂ kinin receptor agonist. [Tyr8] Bradykinin also stimulates ERK1/2 phosphorylation. [Tyr8] Bradykinin can be used as an internal standard .

Cyclosporin D	Nuclear Factor of activated T Cells (NFAT)	Inflammation/Immunology
Cyclosporin D, a metabolite of Cyclosporin A, is a weak immunosuppressant. Cyclosporin D is used as internal standard for quantification of Cyclosporin A . Cyclosporin A is a potent immunosuppressant agent, suppress T cell activation by inhibiting calcineurin and the calcineurin-dependent transcription factors nuclear factor of activated T cells (NFAc) .

Methionyl-Lysyl-Bradykinin Met-Lys-Bradykinin	Bradykinin Receptor	Cardiovascular Disease Endocrinology
Methionyl-Lysyl-Bradykinin (Met-Lys-Bradykinin), a Bradykinin (HY-P0206) analogue, is a kinin .

(Des-Gly10,D-Ala6,Pro-NHEt9)-LHRH Surfagon	GnRH Receptor	Others
(Des-Gly10,D-Ala6,Pro-NHEt9)-LHRH (Surfagon, Mwt 1167.34 Da) is an agonist of gonadotropin-releasing hormone (GnRH). (Des-Gly10,D-Ala6,Pro-NHEt9)-LHRH can be used as an internal standard for the LC-MS analysis of leuprorelide acetate. (Des-Gly10,D-Ala6,Pro-NHEt9)-LHRH has potential applications in biochemical analysis and fertility .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-W004154

2-Ethylbutyric acid	Ketones, Aldehydes, Acids Source classification Other Diseases Pelargonium hortorum Plants Disease Research Fields Geraniaceae	Others
2-Ethylbutyric acid acts as an internal standard (IS) in a standard addition calibration method for the VFA analysis of faeces .

HY-W004285

Methyl undecanoate	Natural Products Classification of Application Fields Source classification Sterculiaceae Sterculia lychnophera Hance Other Diseases Plants Disease Research Fields	Others
Methyl undecanoate is an internal standard in gas-liquid chromatogram .

HY-W016993

2,3,4-Trihydroxybenzoic acid	other families Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Phenols Polyphenols Plants Disease Research Fields	Others
2,3,4-Trihydroxybenzoic acid is an internal standard in separation of phenolic acids by HPLC.

HY-N1393

2-Methoxybenzoic acid NSC 3778; O-Methylsalicylic acid; Salicylic acid methyl ether	Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Disease Research Fields Cancer	Endogenous Metabolite
2-Methoxybenzoic acid (NSC 3778) is used as an internal standard of salicylic acid and its putative biosynthetic precursors in cucumber leaves. Another known use is in the synthesis of Benextramine.

HY-N0808R

Camphor (Standard)	Structural Classification Other Monoterpenes Terpenoids Source classification Plants Lauraceae Cinnamomum camphora	TRP Channel Influenza Virus
Camphor (Standard) is the analytical standard of Camphor. This product is intended for research and analytical applications. Camphor ((±)-Camphor) is a topical anti-infective and anti-pruritic and internally as a stimulant and carminative. However, Camphor is poisonous when ingested. Antiviral, antitussive, and anticancer activities . Camphor is a TRPV3 agonist .

HY-W019721

Cyclosporin D	Structural Classification Natural Products Microorganisms Classification of Application Fields Source classification Inflammation/Immunology Disease Research Fields	Nuclear Factor of activated T Cells (NFAT)
Cyclosporin D, a metabolite of Cyclosporin A, is a weak immunosuppressant. Cyclosporin D is used as internal standard for quantification of Cyclosporin A . Cyclosporin A is a potent immunosuppressant agent, suppress T cell activation by inhibiting calcineurin and the calcineurin-dependent transcription factors nuclear factor of activated T cells (NFAc) .

HY-141579

Sphingosine (d17:1)	Animals Source classification	Others
Sphingosine (d17:1) is a 17-carbon sphingosine found in human skin. Sphingosine (d17:1) can be phosphorylated by sphingosine kinases to produce C-17 sphingosine-1-phosphate. Sphingosine C-17 was used as an internal standard for spectral analysis of sphingoid compounds .

Cat. No.	Product Name	Chemical Structure

HY-B0389A

D-Glucose-13C6 4 Publications Verification
D-Glucose- ¹³C₆ is a stable isotope-labeled counterpart of D-glucose (HY-B0389). D-Glucose- ¹³C₆ can be used as a metabolic tracer to trace glucose-related synthetic catabolism or as synthesis ingredient, minimal media reagent, and internal standard .

HY-113209S

8-Iso-PGF2a-d4

8-Iso-PGF2a-d4 (8-iso Prostaglandin F2α-d4) is an active compound. 8-Iso-PGF2a-d4 can be used the internal standard .

HY-B0870S

Bensulfuron-methyl-d6
Bensulfuron-methyl-d₆ is a deuterated Bensulfuron-methyl (HY-B0870) (sulfonylurea pesticides). Bensulfuron-methyl-d₆ can be used as an internal standard for the determination of pesticide residues by LC-MS[1].

HY-111095S1

D-(-)-Lactic acid-13C
D-(-)-Lactic acid-13C ((R)-2-Hydroxypropionic acid-13C) is a ¹³C-labeled D-Lactic acid. D-(-)-Lactic acid-13C can be used as an internal standard and can also be used in studies such as metabolic tracing.

HY-108353S

Isoprenaline-d7 acetate

Isoprenalin-d7 acetate is an internal standard for the determination of isoproterenol by GC- or LC-MS .
HY-W004285S

Methyl undecanoate-d21

Methyl undecanoate-d₂₁ is the deuterium labeled Methyl undecanoate. Methyl undecanoate is an internal standard in gas-liquid chromatogram[1].
HY-W700539S

N1-Acetyl triethylenetetramine-d4

N1-Acetyl triethylenetetramine-d4 is deuterated N1-Acetyl triethylenetetramine and can be used as an internal standard in plasma extracts .

HY-14865S

Omadacycline-d9
Omadacycline-d9 (PTK 0796-d9; Amadacycline-d9) is the deuterium labeled Omadacycline (HY-14865) that can be used as the internal standard for the analysis of Omadacycline .

HY-N6726S1

Fumonisin B3-13C34-1

Fumonisin B3-13C34-1 is the isotopic internal standard of Fumonisin B3 (HY-N6726). Fumonisin B3 is a mycotoxin derived from fusarium fungi, a member of fumonisins .

HY-18569S

3-Indoleacetic acid-d5 1 Publications Verification
3-Indoleacetic acid-d₅ is the deuterium labeled 3-Indoleacetic acid. 3-Indoleacetic acid-d₅ can be used as internal standard for assay of IAA releases by alkaline hydrolysis of ester and amide conjugates[1].

HY-N1393S

2-Methoxybenzoic acid-13C6
2-Methoxybenzoic acid- ¹³C₆ is the ¹³C-labeled 2-Methoxybenzoic acid. 2-Methoxybenzoic acid (NSC 3778) is used as an internal standard of salicylic acid and its putative biosynthetic precursors in cucumber leaves. Another known use is in the synthesis of Benextramine.

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internal standard

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

NaturalProducts

Isotope-Labeled Compounds

Natural
Products