Search Result
Results for "
internal standard
" in MedChemExpress (MCE) Product Catalog:
3
Biochemical Assay Reagents
18
Isotope-Labeled Compounds
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-B0389A
-
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Glucose-13C6; D-(+)-Glucose-13C6; Dextrose-13C6
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Endogenous Metabolite
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Metabolic Disease
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D-Glucose- 13C6 is a stable isotope-labeled counterpart of D-glucose (HY-B0389). D-Glucose- 13C6 can be used as a metabolic tracer to trace glucose-related synthetic catabolism or as synthesis ingredient, minimal media reagent, and internal standard .
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- HY-18569S
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Indole-3-acetic acid-d5; 3-IAA-d5
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Endogenous Metabolite
Isotope-Labeled Compounds
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Metabolic Disease
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3-Indoleacetic acid-d5 is the deuterium labeled 3-Indoleacetic acid (HY-18569). 3-Indoleacetic acid-d5 can be used as internal standard for assay of IAA releases by alkaline hydrolysis of ester and amide conjugates .
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- HY-W004290
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Methyl margarate
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Environmental Pollutants
Biochemical Assay Reagents
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Others
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Methyl heptadecanoate (Methyl margarate) is a methyl ester derivative of heptadecanoic acid (HY-W004284). Methyl heptadecanoate is used as an internal standard for the quantitative calibration of fatty acids in GC-MS analysis .
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- HY-W004262
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Biochemical Assay Reagents
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Others
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Methyl nonadecanoate is an internal standard. Methyl nonadecanoate can be used to determine the content of fatty acid methyl esters (FAME) in biodiesel .
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- HY-W068212
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Juniperic acid
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Drug Intermediate
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Metabolic Disease
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16-Hydroxyhexadecanoic acid (Juniperic acid) is one of the main monomers of cutin in Vicia faba flower petals. 16-Hydroxyhexadecanoic acid can be used as an internal standard for the measurement of hydroxy and hydroperoxy fatty acids in plasma .
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- HY-W019721
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Nuclear Factor of activated T Cells (NFAT)
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Inflammation/Immunology
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Cyclosporin D, a metabolite of Cyclosporin A, is a weak immunosuppressant. Cyclosporin D is used as internal standard for quantification of Cyclosporin A . Cyclosporin A is a potent immunosuppressant agent, suppress T cell activation by inhibiting calcineurin and the calcineurin-dependent transcription factors nuclear factor of activated T cells (NFAc) .
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- HY-W016371
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3,4,5-threechlorine pyridine
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Biochemical Assay Reagents
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Others
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3,4,5-Trichloropyridine is a chlorinated pyridine compound and also serves as an internal standard for quantitative proton nuclear magnetic resonance spectroscopy .
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- HY-115703
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N-Heptadecanoyl-D-erythro-sphingosine
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Biochemical Assay Reagents
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Metabolic Disease
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C17 Ceramide (d18:1/17:0) (N-Heptadecanoyl-D-erythro-sphingosine) is a phospholipid internal standard. C17 Ceramide (d18:1/17:0) is used in studies of medium-chain acyl-CoA dehydrogenase deficiency (MCADD) .
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- HY-W004290S
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Isotope-Labeled Compounds
Biochemical Assay Reagents
Drug Derivative
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Others
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Methyl heptadecanoate-d33 is the deuterium labeled Methyl heptadecanoate (HY-W004290). Methyl heptadecanoate (C17:0 methyl ester) is the methyl ester derivative of heptadecanoic acid (HY-W004284). Methyl heptadecanoate is used as an internal standard for quantitative calibration of fatty acids in GC-MS analysis .
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- HY-112552
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DSG; 1,2-Dioctadecanoyl-sn-glycerol
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Endogenous Metabolite
Biochemical Assay Reagents
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Others
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1,2-Distearoyl-sn-glycerol (DSG) is a glyceride compound. 1,2-Distearoyl-sn-glycerol can be used as an internal standard for the analysis of molecular species of diacylglycerol (DAG) and other phospholipids in rat brain .
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- HY-141632
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Heptadecasphinganine
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Bacterial
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Infection
Neurological Disease
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Sphinganine-C17 (Heptadecasphinganine) is a synthetic bioactive sphingolipid and an isomer of sphinganine. Sphinganine-C17 inhibits the growth of Candida glabrata and Candida albicans with a minimum bactericidal concentration (MBC) of 0.5 μg/mL for both. Sphinganine-C17 can be used as an internal standard for the chromatographic analysis of sphingosine compounds .
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- HY-P4463
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GnRH Receptor
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Others
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(Des-Pyr1)-LHRH is a Polypeptide Internal Standard, identical to (Des-Pyr1)-GnRH, which can be identified through peptide screening. Peptide screening is a research tool that mainly collects active polypeptides via immunoassays. It can be applied to protein interaction, functional analysis, epitope screening, especially in the field of active molecule research and development. (Des-Pyr1)-LHRH can serve as an internal standard (ISTD) for mass spectrometry analysis .
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- HY-107935
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Fluprednisolone
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Biochemical Assay Reagents
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Inflammation/Immunology
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6α-Fluoroprednisolone (Fluprednisolone) is an internal standard for methylprednisolone, prednisolone and prednisone. 6α-Fluoroprednisolone is an anti-inflammatory agent. 6α-Fluoroprednisolone can be used for congenital adrenal virilism and Addison's disease research .
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- HY-N0086R
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6-Methyladenosine (standard); N-Methyladenosine (standard)
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Endogenous Metabolite
Influenza Virus
Reference Standards
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Infection
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N6-Methyladenosine (Standard) is the analytical standard of N6-Methyladenosine. This product is intended for research and analytical applications. N6-Methyladenosine is the most prevalent internal (non-cap) modification present in the messenger RNA (mRNA) of all higher eukaryotes. N6-Methyladenosine can modifies viral RNAs and has antiviral activities.
In Vitro: N6-methyladenosine (m6A) is selectively recognized by the human YTH domain family 2 (YTHDF2) protein to regulate mRNA degradation. N6-methyladenosine (m6A), a prevalent internal modification in the messenger RNA of all eukaryotes, is post-transcriptionally installed by m6A methyltransferase (e.g., MT-A70) within the consensus sequence of G(m6A)C (70%) or A(m6A)C (30%). N6-methyladenosine (m6A)-containing RNAs are greatly enriched in the YTHDF-bound portion and diminished in the flow-through portion . N6-methyladenosine (m6A), the most abundant internal RNA modification, functions in diverse biological processes, including regulation of embryonic stem cell self-renewal and differentiation. N6-methyladenosine (m6A) is a large protein complex, consisting in part of methyltransferase-like 3 (METTL3) and methyltransferase-like 14 (METTL14) catalytic subunits .
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- HY-P0048
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Surfagon
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GnRH Receptor
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Others
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(Des-Gly10,D-Ala6,Pro-NHEt9)-LHRH (Surfagon, Mwt 1167.34 Da) is an agonist of gonadotropin-releasing hormone (GnRH). (Des-Gly10,D-Ala6,Pro-NHEt9)-LHRH can be used as an internal standard for the LC-MS analysis of leuprorelide acetate. (Des-Gly10,D-Ala6,Pro-NHEt9)-LHRH has potential applications in biochemical analysis and fertility .
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- HY-A0135
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Potassium Channel
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Neurological Disease
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Enflurane, a volatile anaesthetic, is a potent inhibitor of high conductance Ca 2+-activated K+ channels of Chara australis. Enflurane is an internal standard in monitoring halogenated volatile anaesthetics by headspace gas chromatography-mass spectrometry .
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- HY-111095S1
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(R)-2-Hydroxypropionic acid-13C; D-Lactic acid-13C
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Isotope-Labeled Compounds
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Others
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D-(-)-Lactic acid- 13C ((R)-2-Hydroxypropionic acid- 13C) is a 13C-labeled D-Lactic acid. D-(-)-Lactic acid- 13C can be used as an internal standard and can also be used in studies such as metabolic tracing.
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- HY-W004154
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Environmental Pollutants
Biochemical Assay Reagents
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Others
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2-Ethylbutyric acid is a volatile fatty acid. 2-Ethylbutyric acid exhibits phytotoxicity. 2-Ethylbutyric acid is used as an internal standard in milk and dairy products and as an internal standard (IS) in the calibration of fecal VFA standards. 2-Ethylbutyric acid can be used in the research of embryonic development .
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- HY-W016993
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Amylases
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Others
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2,3,4-Trihydroxybenzoic acid is an internal standard in separation of phenolic acids by HPLC.
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- HY-N7868
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Biochemical Assay Reagents
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Others
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Methyl tricosanoate is a saturated fatty acid methyl ester and also serves as an internal standard, which can be used for the quantitative analysis of neuraminic acid (NA) concentration .
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- HY-N0808R
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(±)-Camphor (standard)
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Reference Standards
TRP Channel
Influenza Virus
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Infection
Inflammation/Immunology
Cancer
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Camphor (Standard) is the analytical standard of Camphor. This product is intended for research and analytical applications. Camphor ((±)-Camphor) is a topical anti-infective and anti-pruritic and internally as a stimulant and carminative. However, Camphor is poisonous when ingested. Antiviral, antitussive, and anticancer activities . Camphor is a TRPV3 agonist .
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- HY-14865S
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PTK 0796-d9; Amadacycline-d9
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Bacterial
Isotope-Labeled Compounds
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Others
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Omadacycline-d9 (PTK 0796-d9; Amadacycline-d9) is the deuterium labeled Omadacycline (HY-14865) that can be used as the internal standard for the analysis of Omadacycline .
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- HY-P3751
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- HY-34611
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N-Boc-L-2,4-diaminobutyric acid; Boc-Dab-OH
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Drug Intermediate
ASCT
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Neurological Disease
Cancer
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Boc-L-2,4-Diaminobutyric acid (N-Boc-L-2,4-diaminobutyric acid; Boc-Dab-OH) is a versatile synthetic starting material with a cleavable protecting group. Boc-L-2,4-Diaminobutyric acid not only reduces the backbone cleavage rate by protecting the side-chain γ-amino group, but also triggers intramolecular cyclization of self-immolative linkers under acidic cleavage conditions, thus constructing stimuli-responsive materials. Boc-L-2,4-Diaminobutyric acid is also an important building block for bioactive molecules. It can be used in the synthesis of ASCT2 (SLC1A5) inhibitors and carboxynorspermine, and can also serve as an internal standard to support the quantitative detection of specific intracellular amino acids by UPLC-QQQ-MS .
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- HY-131676
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SM (d18:1/17:0); Heptadecanoyl Sphingomyelin; N-Heptadecanoyl-D-erythro-Sphingosylphosphorylcholine
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Endogenous Metabolite
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Metabolic Disease
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C17 Sphingomyelin is a synthetic derivative of sphingomyelin that has been used as an internal standard for the quantification of sphingomyelin.
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- HY-110225
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UCB L059-d6 (ring-d6)
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Others
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Others
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Levetiracetam-d6 (ring-d6) can be used as internal standard for the determination of Levetiracetam (HY-B0106) content in whole blood .
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- HY-W707056
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Biochemical Assay Reagents
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Others
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Latanoprost acid-d4 is used as the internal standard in the HPLC-MS/MS analysis to determine the level of Latanoprost acid (HY-113756A) in aqueous humor samples of eyes .
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- HY-113209S
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- HY-W127391
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(Rac)-1,2-Didodecanoylglycerol
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Biochemical Assay Reagents
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Others
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1,2-Dilaurin is a diacylglycerol containing lauric acid at the sn-1 and sn-2 positions. It has been used as an internal standard for the quantification of diglycerides in rat desheathed sciatic nerves. [1] Monomolecular films containing 1,2-dilauroyl-rac-glycerol have been used as substrates to measure surface pressure and the effect of pancreatic procolipase and colipase on porcine pancreatic lipase activity. [2] References: [1]. Zhu, X. and Eichberg, J. 1,2-Diacylglycerol content and its arachidonyl-containing molecular species are reduced in the sciatic nerve of streptozotocin-induced diabetic rats. J. Neurochemistry. 55(3), 1087-1090 (1990).[2]. Wieloch, T., Borgstr m, B., Piéroni, G. et al. Porcine trypsinogen and its trypsin-activated form: lipid binding and lipase activation on monomolecular membranes. FEBS Express. 128(2), 217-220 (1981).
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- HY-B0870S
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Isotope-Labeled Compounds
Herbicide
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Others
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Bensulfuron-methyl-d6 is a deuterated Bensulfuron-methyl (HY-B0870). Bensulfuron-methyl is a kind of sulfonylurea herbicide widely used to control broad-leaf weeds in rice paddies .
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- HY-W004285
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- HY-W016993R
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- HY-131389
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Biochemical Assay Reagents
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Others
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Cholesteryl heptadecanoate is a cholesteryl ester internal standard that accurately determines the concentration of free cholesterol in cells without hydrolyzing triglycerides. Cholesteryl heptadecanoate can be used for the quantitative determination of cholesteryl esters by GC or LC mass spectrometry .
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- HY-W010378R
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H-D-Asn-OH (standard)
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Reference Standards
Endogenous Metabolite
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Metabolic Disease
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D-Asparagine (Standard) (H-D-Asn-OH (Standard)) is the analytical standard of D-Asparagine (HY-W010378). This product is intended for research and analytical applications. D-Asparagine (H-D-Asn-OH) is a competitive inhibitor of L-Asparagine hydrolysis with a Ki value of 0.24 mM. D-Asparagine is a source of nitrogen for yeast strains. D-Asparagine is a good substrate for the external yeast asparaginase but is a poor substrate for the internal enzyme.
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- HY-P3750
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- HY-D1674
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Fluorescent Dye
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Others
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Sulforhodamine G is a fluorescent stain with broad dynamic ranges. Sulforhodamine G can be used for the research of protein stains .
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- HY-W012606
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- HY-141642
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Glycerol triheptadecanoate; Trimargarin
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Biochemical Assay Reagents
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Others
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Triheptadecanoin (Glycerol triheptadecanoate) is an internal standard for the rapid GC analysis of fatty acid methyl esters in edible fats and oils. Triheptadecanoin enables the quantitative analysis of trans-fatty acid content in edible fats and oils via a rapid GC method. Triheptadecanoin smoothly undergoes methylation with m-TFPTAH in toluene solution at room temperature .
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- HY-W643167
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Glycerol Tritridecanoyl; 13:0 TAG; 13:0/13:0/13:0-TG
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Biochemical Assay Reagents
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Infection
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1,2,3-Tritridecanoyl glycerol is a synthetic triacylglycerol that contains tridecanoic acid in the sn-1, sn-2, and sn-3 positions. It has been used as a standard for the relative quantification of triacylglycerols in C. elegans fat stores. It has also been used as an internal standard for the quantification of triacylglycerols in the serum and liver of adult rat offspring receiving dietary conjugated linoleic acids during and after gestation.
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- HY-113958R
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LM-2219 (standard)
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TrxR
Reference Standards
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Others
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Difethialone (Standard) is the analytical standard of Difethialone. This product is intended for research and analytical applications. Difethialone (LM-2219) is an anticoagulant rodenticide. Difethialone shows high rodenticide activity in warfarin-sensitive and resistant strains of rats and mice. Difethialone interferes with the circulation of vitamin K in the liver, preventing the synthesis of coagulation factors, resulting in the inability of the blood to coagulate properly, ultimately causing internal bleeding and death. Difethialone can be used in studies of ecological impacts .
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- HY-W725954
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Biochemical Assay Reagents
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Others
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Triheneicosanoin is a triacylglycerol containing heneicosanoic acid groups. Triheneicosanoin can be used as internal standard for the quantification of fatty acids in the milk samples .
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- HY-W004285R
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Reference Standards
Others
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Others
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Methyl undecanoate (Standard) is the analytical standard of Methyl undecanoate. This product is intended for research and analytical applications. Methyl undecanoate is an internal standard in gas-liquid chromatogram .
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- HY-108353S
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- HY-W004154R
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Biochemical Assay Reagents
Reference Standards
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Others
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2-Ethylbutyric acid (Standard) is an analytical standard of 2-Ethylbutyric acid (HY-W004154). This product is intended for research and analytical applications. 2-Ethylbutyric acid is a volatile fatty acid. 2-Ethylbutyric acid exhibits phytotoxicity. 2-Ethylbutyric acid is used as an internal standard in milk and dairy products and as an internal standard (IS) in the calibration of fecal VFA standards. 2-Ethylbutyric acid can be used in the research of embryonic development .
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- HY-132569S
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- HY-W700539S
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Isotope-Labeled Compounds
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Others
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N1-Acetyl triethylenetetramine-d4 is deuterated N1-Acetyl triethylenetetramine and can be used as an internal standard in plasma extracts .
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- HY-138127
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Biochemical Assay Reagents
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Others
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Gendenafil is an analog of Sildenafil (HY-15025). Gendenafil can be used as internal standard for quantitative analysis of Sildenafil (HY-15025), Tadalafil (HY-90009A), and Vardenafil (HY-B0442) .
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- HY-W354544
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Dihydrodiethylstilbestrol
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Estrogen Receptor/ERR
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Endocrinology
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(Rac)-Hexestrol is the racemic form of Hexestrol (HY-B1662). Hexestrol is a synthetic non-steroidal estrogen. (Rac)-Hexestrol usually appears in deuterated form and is used as an internal standard for precise quantitative analysis in analytical chemistry.
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- HY-W004290R
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Methyl margarate (standard)
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Reference Standards
Biochemical Assay Reagents
Drug Derivative
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Others
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Methyl heptadecanoate (Standard) is the analytical standard of Methyl heptadecanoate (HY-W004290). This product is intended for research and analytical applications. Methyl heptadecanoate (C17:0 methyl ester) is the methyl ester derivative of heptadecanoic acid (HY-W004284). Methyl heptadecanoate is used as an internal standard for quantitative calibration of fatty acids in GC-MS analysis .
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- HY-W020041
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Autophagy
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Neurological Disease
Cancer
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CP 53631 is an autophagy inhibitor (Autophagy) with anticancer activity. Additionally, CP 53631 can be used as an internal standard for Sertraline (HY-B0176A) in research related to selective serotonin reuptake inhibitors (SSRIs) in the field of antidepressants .
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- HY-115705
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Glycerol tri-10(Z)-heptadecenoate; TG(17:1/17:1/17:1); Tri-10(Z)-heptadecenoin
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Biochemical Assay Reagents
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Others
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1,2,3-Tri-10(Z)-heptadecenoyl glycerol (TG(17:1/17:1/17:1)) is a biochemical assay reagent, which can be used as an internal standard for the quantification of biological triglyceride .
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- HY-W019721R
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Reference Standards
Nuclear Factor of activated T Cells (NFAT)
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Inflammation/Immunology
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Cyclosporin D (Standard) is the analytical standard of Cyclosporin D. This product is intended for research and analytical applications. Cyclosporin D, a metabolite of Cyclosporin A, is a weak immunosuppressant. Cyclosporin D is used as internal standard for quantification of Cyclosporin A . Cyclosporin A is a potent immunosuppressant agent, suppress T cell activation by inhibiting calcineurin and the calcineurin-dependent transcription factors nuclear factor of activated T cells (NFAc) .
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- HY-N2344R
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Proanthocyanidin A1 (standard)
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Reference Standards
PKC
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Inflammation/Immunology
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Procyanidin A1 (Standard) is the analytical standard of Procyanidin A1. This product is intended for research and analytical applications. Procyanidin A1 (Proanthocyanidin A1) is a procyanidin dimer, which inhibits degranulation downstream of protein kinase C activation or Ca2+ influx from an internal store in RBL-213 cells. Procyanidin A1 has antiallergic effects .
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- HY-109513R
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Biochemical Assay Reagents
Reference Standards
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Others
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Ioxilan (Standard) is the analytical standard of Ioxilan. This product is intended for research and analytical applications. Ioxilan is a low-osmolar, nonionic and tri-iodinated diagnostic contrast agent. Ioxilan is also an X-ray contrast agent for excretory urography and contrast enhanced computed tomographic (CECT) imaging of the head and body. Intravascular injection results in opacification of vessels in the path of flow of the contrast medium, permitting radiographic visualization of the internal structures of the human body until significant hemodilution occurs .
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- HY-W706672
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Glycerol Tritricosanoate; TG(23:0/23:0/23:0); Tritricosanoin
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Endogenous Metabolite
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Metabolic Disease
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1,2,3-Tritricosanoyl glycerol is a triacylglycerol that contains tricosanoic acid (HY-W009081) at the sn-1, sn-2, and sn-3 positions. It has been used as an internal standard for the quantification of fatty acids in the triglyceride component of human aortic endothelial cells (HAECs) grown in media supplemented with stearic and/or oleic acid.
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- HY-N6726S1
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Isotope-Labeled Compounds
Fungal
Endogenous Metabolite
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Infection
Cancer
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Fumonisin B3-13C34-1 is the isotopic internal standard of Fumonisin B3 (HY-N6726). Fumonisin B3 is an orally active fumonisin Mycotoxin. Fumonisin B3 can be isolated from Fusarium moniliforme, Fusarium proliferatum and Fusarium nygamai. Fumonisin B3 induces precancerous lesions, triggers embryonic death of chicken embryos, causes severe hemorrhage in dead chicken embryos. Fumonisin B3 can be used in studies related to hepatocellular carcinoma .
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- HY-W750595
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Drug Derivative
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Cancer
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6-(L-1,2,3-Trihydroxybutyl)-pterin is a derivative of L-biopterin (HY-102015) and is the oxidized form of tetrahydro-L-biopterin (BH4) as well as D-biopterin. Co-ingestion of 6-(L-1,2,3-Trihydroxybutyl)-pterin (0.5%) with the carcinogen 4-dimethylaminoazobenzene reduces the incidence of 4-dimethylaminoazobenzene-induced liver tumors in rats. 6-(L-1,2,3-Trihydroxybutyl)-pterin has been used as an internal standard for the LC-MS quantification of biopterin and neopterin in rat plasma.
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- HY-163691
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Carbonic Anhydrase
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Cancer
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Antitumor agent-163 (Compound 3) is a photosensitizer used in Molecular-Targeted Photodynamic Therapy (MT-PDT) targeting carbonic anhydrase IX (CAIX). Antitumor agent-163 inactivates CAIX protein via singlet oxygen under 540 nm wavelength light, without affecting internal standard proteins such as α-tubulin, β-actin, and proliferating cell nuclear antigen (PCNA). Antitumor agent-163 induces cell membrane damage, inhibits cell viability (IC50 is 0.2 and 0.05 μM for A549 and U87MG). Antitumor agent-163 exhibits antitumor efficacy in mouse model .
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- HY-W099771
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p-Propylanisole
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Environmental Pollutants
Biochemical Assay Reagents
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Others
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4-Propylanisole (p-Propylanisole) is a biochemical analysis reagent. Structurally similar to Estragole (HY-N5060), 4-Propylanisole can be used as an internal standard for the GC-MS quantification of Estragole in fennel tea .
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- HY-164158
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Drug Derivative
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Others
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N,N-Dimethyl psychosine is a derivative of Psychosine (HY-136490). N,N-Dimethyl psychosine can be used as an internal standard compound to quantify Psychosine in alkaline-treated lipid extracts .
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- HY-182574MS
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- HY-181859MS
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Isotope-Labeled Compounds
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Others
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EPA method 533 isotope performance standard 1-3 mg/mL in methanol:water is a mixed standard of isotope internal standards.
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- HY-181844MS
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- HY-W068212R
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- HY-W004285S
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Isotope-Labeled Compounds
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Others
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Methyl undecanoate-d21 is the deuterium labeled Methyl undecanoate. Methyl undecanoate is an internal standard in gas-liquid chromatogram .
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- HY-N13079
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Others
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Others
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3-Epicinobufagin (compound IX) can be used as an internal standard for the metabolism of Bufalin (HY-N0877), by detecting its content in serum and urine to provide feedback on the corresponding metabolic status .
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- HY-156196
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Syk
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Inflammation/Immunology
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BI 894416 is a spleen tyrosine kinase (SYK) inhibitor. BI 894416 has a deuterium-labeled derivative that can be used as an internal standard for bioanalytical studies. BI 894416 is applicable to the research of severe asthma .
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- HY-W706672R
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Glycerol Tritricosanoate (standard); TG(23:0/23:0/23:0) (standard); Tritricosanoin (standard)
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Endogenous Metabolite
Reference Standards
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Metabolic Disease
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Propane-1,2,3-triyl tritricosanoate (Standard) is the analytical standard of Propane-1,2,3-triyl tritricosanoate. This product is intended for research and analytical applications. 1,2,3-Tritricosanoyl glycerol is a triacylglycerol that contains tricosanoic acid (HY-W009081) at the sn-1, sn-2, and sn-3 positions. It has been used as an internal standard for the quantification of fatty acids in the triglyceride component of human aortic endothelial cells (HAECs) grown in media supplemented with stearic and/or oleic acid.
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- HY-W068212S
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Juniperic acid-13C2
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Isotope-Labeled Compounds
Drug Intermediate
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Metabolic Disease
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16-Hydroxyhexadecanoic acid- 13C2 (Juniperic acid- 13C2) is the 13C-labeled 16-Hydroxyhexadecanoic acid (HY-W068212). 16-Hydroxyhexadecanoic acid (Juniperic acid) is one of the main monomers of cutin in Vicia faba flower petals. 16-Hydroxyhexadecanoic acid can be used as an internal standard for the measurement of hydroxy and hydroperoxy fatty acids in plasma
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- HY-101931R
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Reference Standards
VEGFR
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Cancer
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hVEGF-IN-1 (Standard) is the analytical standard of hVEGF-IN-1 (HY-101931). This product is intended for research and analytical applications. hVEGF-IN-1, a quinazoline derivative, could specifically bind to the G-rich sequence in the internal ribosome entry site A (IRES-A) and destabilize the G-quadruplex structure. hVEGF-IN-1 binds to the IRES-A (WT) with a Kd of 0.928 μM in SPR experiments. hVEGF-IN-1 could hinder tumor cells migration and repress tumor growth by decreasing VEGF-A protein expression .
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- HY-107146R
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P1pal-7 (standard)
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Reference Standards
Protease Activated Receptor (PAR)
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Cardiovascular Disease
Cancer
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PZ-128 (Standard) (P1pal-7 (Standard)) is the analytical standard of PZ-128 (HY-107146). This product is intended for research and analytical applications. PZ-128 (P1pal-7), a cell-penetrating lipopeptide pepducin, is a first-in-class, specific and reversible protease-activated receptor-1 (PAR1) antagonist. PZ-128 targets the cytoplasmic surface of PAR1 and interrupts signaling to internally-located G (PAR1-G) proteins. PZ-128 has antiplatelet, anti-metastatic, anti-angiogenic and anticancer effects .
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- HY-W710512
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Glycerol Tritricosanoate-d5; TG(23:0/23:0/23:0)-d5; Tritricosanoin-d5
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Isotope-Labeled Compounds
Endogenous Metabolite
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Metabolic Disease
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Propane-1,2,3-triyl tritricosanoate-d5 (Glycerol Tritricosanoate-d5) is deuterium labeled Propane-1,2,3-triyl tritricosanoate. 1,2,3-Tritricosanoyl glycerol is a triacylglycerol that contains tricosanoic acid (HY-W009081) at the sn-1, sn-2, and sn-3 positions. It has been used as an internal standard for the quantification of fatty acids in the triglyceride component of human aortic endothelial cells (HAECs) grown in media supplemented with stearic and/or oleic acid.
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Product Name |
Type |
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- HY-W016371
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3,4,5-threechlorine pyridine
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Biochemical Assay Reagents
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3,4,5-Trichloropyridine is a chlorinated pyridine compound and also serves as an internal standard for quantitative proton nuclear magnetic resonance spectroscopy .
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- HY-N7868
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Biochemical Assay Reagents
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Methyl tricosanoate is a saturated fatty acid methyl ester and also serves as an internal standard, which can be used for the quantitative analysis of neuraminic acid (NA) concentration .
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- HY-W127391
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(Rac)-1,2-Didodecanoylglycerol
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Biochemical Assay Reagents
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1,2-Dilaurin is a diacylglycerol containing lauric acid at the sn-1 and sn-2 positions. It has been used as an internal standard for the quantification of diglycerides in rat desheathed sciatic nerves. [1] Monomolecular films containing 1,2-dilauroyl-rac-glycerol have been used as substrates to measure surface pressure and the effect of pancreatic procolipase and colipase on porcine pancreatic lipase activity. [2] References: [1]. Zhu, X. and Eichberg, J. 1,2-Diacylglycerol content and its arachidonyl-containing molecular species are reduced in the sciatic nerve of streptozotocin-induced diabetic rats. J. Neurochemistry. 55(3), 1087-1090 (1990).[2]. Wieloch, T., Borgstr m, B., Piéroni, G. et al. Porcine trypsinogen and its trypsin-activated form: lipid binding and lipase activation on monomolecular membranes. FEBS Express. 128(2), 217-220 (1981).
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Product Name |
Target |
Research Area |
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- HY-W019721
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Nuclear Factor of activated T Cells (NFAT)
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Inflammation/Immunology
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Cyclosporin D, a metabolite of Cyclosporin A, is a weak immunosuppressant. Cyclosporin D is used as internal standard for quantification of Cyclosporin A . Cyclosporin A is a potent immunosuppressant agent, suppress T cell activation by inhibiting calcineurin and the calcineurin-dependent transcription factors nuclear factor of activated T cells (NFAc) .
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- HY-P4463
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GnRH Receptor
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Others
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(Des-Pyr1)-LHRH is a Polypeptide Internal Standard, identical to (Des-Pyr1)-GnRH, which can be identified through peptide screening. Peptide screening is a research tool that mainly collects active polypeptides via immunoassays. It can be applied to protein interaction, functional analysis, epitope screening, especially in the field of active molecule research and development. (Des-Pyr1)-LHRH can serve as an internal standard (ISTD) for mass spectrometry analysis .
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- HY-P0048
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Surfagon
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GnRH Receptor
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Others
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(Des-Gly10,D-Ala6,Pro-NHEt9)-LHRH (Surfagon, Mwt 1167.34 Da) is an agonist of gonadotropin-releasing hormone (GnRH). (Des-Gly10,D-Ala6,Pro-NHEt9)-LHRH can be used as an internal standard for the LC-MS analysis of leuprorelide acetate. (Des-Gly10,D-Ala6,Pro-NHEt9)-LHRH has potential applications in biochemical analysis and fertility .
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- HY-P3751
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- HY-34611
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N-Boc-L-2,4-diaminobutyric acid; Boc-Dab-OH
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Drug Intermediate
ASCT
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Neurological Disease
Cancer
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Boc-L-2,4-Diaminobutyric acid (N-Boc-L-2,4-diaminobutyric acid; Boc-Dab-OH) is a versatile synthetic starting material with a cleavable protecting group. Boc-L-2,4-Diaminobutyric acid not only reduces the backbone cleavage rate by protecting the side-chain γ-amino group, but also triggers intramolecular cyclization of self-immolative linkers under acidic cleavage conditions, thus constructing stimuli-responsive materials. Boc-L-2,4-Diaminobutyric acid is also an important building block for bioactive molecules. It can be used in the synthesis of ASCT2 (SLC1A5) inhibitors and carboxynorspermine, and can also serve as an internal standard to support the quantitative detection of specific intracellular amino acids by UPLC-QQQ-MS .
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- HY-P3750
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- HY-W019721R
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Reference Standards
Nuclear Factor of activated T Cells (NFAT)
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Inflammation/Immunology
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Cyclosporin D (Standard) is the analytical standard of Cyclosporin D. This product is intended for research and analytical applications. Cyclosporin D, a metabolite of Cyclosporin A, is a weak immunosuppressant. Cyclosporin D is used as internal standard for quantification of Cyclosporin A . Cyclosporin A is a potent immunosuppressant agent, suppress T cell activation by inhibiting calcineurin and the calcineurin-dependent transcription factors nuclear factor of activated T cells (NFAc) .
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- HY-107146R
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P1pal-7 (standard)
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Reference Standards
Protease Activated Receptor (PAR)
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Cardiovascular Disease
Cancer
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PZ-128 (Standard) (P1pal-7 (Standard)) is the analytical standard of PZ-128 (HY-107146). This product is intended for research and analytical applications. PZ-128 (P1pal-7), a cell-penetrating lipopeptide pepducin, is a first-in-class, specific and reversible protease-activated receptor-1 (PAR1) antagonist. PZ-128 targets the cytoplasmic surface of PAR1 and interrupts signaling to internally-located G (PAR1-G) proteins. PZ-128 has antiplatelet, anti-metastatic, anti-angiogenic and anticancer effects .
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| Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
| Cat. No. |
Product Name |
Chemical Structure |
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- HY-B0389A
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D-Glucose- 13C6 is a stable isotope-labeled counterpart of D-glucose (HY-B0389). D-Glucose- 13C6 can be used as a metabolic tracer to trace glucose-related synthetic catabolism or as synthesis ingredient, minimal media reagent, and internal standard .
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- HY-18569S
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2 Publications Verification
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3-Indoleacetic acid-d5 is the deuterium labeled 3-Indoleacetic acid (HY-18569). 3-Indoleacetic acid-d5 can be used as internal standard for assay of IAA releases by alkaline hydrolysis of ester and amide conjugates .
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- HY-W004290S
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Methyl heptadecanoate-d33 is the deuterium labeled Methyl heptadecanoate (HY-W004290). Methyl heptadecanoate (C17:0 methyl ester) is the methyl ester derivative of heptadecanoic acid (HY-W004284). Methyl heptadecanoate is used as an internal standard for quantitative calibration of fatty acids in GC-MS analysis .
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- HY-111095S1
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D-(-)-Lactic acid- 13C ((R)-2-Hydroxypropionic acid- 13C) is a 13C-labeled D-Lactic acid. D-(-)-Lactic acid- 13C can be used as an internal standard and can also be used in studies such as metabolic tracing.
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- HY-14865S
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Omadacycline-d9 (PTK 0796-d9; Amadacycline-d9) is the deuterium labeled Omadacycline (HY-14865) that can be used as the internal standard for the analysis of Omadacycline .
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- HY-W707056
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Latanoprost acid-d4 is used as the internal standard in the HPLC-MS/MS analysis to determine the level of Latanoprost acid (HY-113756A) in aqueous humor samples of eyes .
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- HY-113209S
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8-Iso-PGF2a-d4 (8-iso Prostaglandin F2α-d4) is an active compound. 8-Iso-PGF2a-d4 can be used the internal standard .
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- HY-B0870S
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Bensulfuron-methyl-d6 is a deuterated Bensulfuron-methyl (HY-B0870). Bensulfuron-methyl is a kind of sulfonylurea herbicide widely used to control broad-leaf weeds in rice paddies .
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- HY-W717950
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Pseudomonas quinolone signal-d4 is a stable isotope internal standard .
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- HY-123023
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12(S)-HETE-d8 contains eight deuterium atoms at the 5, 6, 8, 9, 11, 12, 14 and 15 positions. 12(S)-HETE-d8 is intended for use as an internal standard for the quantification of 12(S)-HETE by GC- or LC-mass spectrometry (MS). 12(S)-HETE-d8 is the predominant lipoxygenase product of mammalian platelets. It enhances tumor cell adhesion to endothelial cells, fibronectin, and the subendothelial matrix at 0.1 µM.
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- HY-108353S
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Isoprenalin-d7 acetate is an internal standard for the determination of isoproterenol by GC- or LC-MS .
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- HY-132569S
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8-Hydroxy warfarin-d5 can be used as an internal standard for the quantification of Warfarin and its known metabolites .
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- HY-W700539S
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N1-Acetyl triethylenetetramine-d4 is deuterated N1-Acetyl triethylenetetramine and can be used as an internal standard in plasma extracts .
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- HY-115705
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1,2,3-Tri-10(Z)-heptadecenoyl glycerol (TG(17:1/17:1/17:1)) is a biochemical assay reagent, which can be used as an internal standard for the quantification of biological triglyceride .
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- HY-N6726S1
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Fumonisin B3-13C34-1 is the isotopic internal standard of Fumonisin B3 (HY-N6726). Fumonisin B3 is an orally active fumonisin Mycotoxin. Fumonisin B3 can be isolated from Fusarium moniliforme, Fusarium proliferatum and Fusarium nygamai. Fumonisin B3 induces precancerous lesions, triggers embryonic death of chicken embryos, causes severe hemorrhage in dead chicken embryos. Fumonisin B3 can be used in studies related to hepatocellular carcinoma .
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- HY-W004285S
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Methyl undecanoate-d21 is the deuterium labeled Methyl undecanoate. Methyl undecanoate is an internal standard in gas-liquid chromatogram .
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- HY-W068212S
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16-Hydroxyhexadecanoic acid- 13C2 (Juniperic acid- 13C2) is the 13C-labeled 16-Hydroxyhexadecanoic acid (HY-W068212). 16-Hydroxyhexadecanoic acid (Juniperic acid) is one of the main monomers of cutin in Vicia faba flower petals. 16-Hydroxyhexadecanoic acid can be used as an internal standard for the measurement of hydroxy and hydroperoxy fatty acids in plasma
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- HY-W710512
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Propane-1,2,3-triyl tritricosanoate-d5 (Glycerol Tritricosanoate-d5) is deuterium labeled Propane-1,2,3-triyl tritricosanoate. 1,2,3-Tritricosanoyl glycerol is a triacylglycerol that contains tricosanoic acid (HY-W009081) at the sn-1, sn-2, and sn-3 positions. It has been used as an internal standard for the quantification of fatty acids in the triglyceride component of human aortic endothelial cells (HAECs) grown in media supplemented with stearic and/or oleic acid.
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| Cat. No. |
Product Name |
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Classification |
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- HY-131389
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Cholesterol
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Cholesteryl heptadecanoate is a cholesteryl ester internal standard that accurately determines the concentration of free cholesterol in cells without hydrolyzing triglycerides. Cholesteryl heptadecanoate can be used for the quantitative determination of cholesteryl esters by GC or LC mass spectrometry .
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