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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
24 Results for "
matriptase
" in MedChemExpress (MCE) Product Catalog:
Products (24)
24 Results for "matriptase" in MCE Product Catalog:
43
43 Publications Verification
Synonyms: Camostat mesilate; FOY305; FOY-S980
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2
2 Cited Publications
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SRI 31215 (TFA) is a Matriptase/Hepsin/hepatocyte growth factor activator (HGFA) triplex inhibitor and mimics the activity of HAI-1/2 (endogenous inhibitors of HGF activation). SRI 31215 has potent inhibitory activity against matriptase, hepsin and HGFA with IC50 values of 0.69 μM, 0.65 μM and 0.30 μM, respectively. SRI 31215 can be used for the research of cancer .
Cat. No.: HY-W783268A
CAS No.: 1268874-09-4
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Matriptase-IN-2 is a secondary amide inhibitor of matriptase derived from sulfonylated 3-amidinophenylalanine, with a Ki value of 5 nM. Matriptase acts as a novel initiator of cartilage matrix degradation in osteoarthritis, and Matriptase-IN-2 inhibits matriptase-mediated cartilage degradation. Matriptase-IN-2 is applicable for the research of osteoarthritis .
Cat. No.: HY-W783268
CAS No.: 1268874-08-3
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Matriptase-IN-2 free base is a matriptase inhibitor with a Ki of 5 nM. Matriptase-IN-2 has the potential for musculoskeletal system disorder research (WO2011023958A1; compound 432) .
Cat. No.: HY-130136A
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TMPRSS6-IN-1 (TFA) is a potent inhibitor of TMPRSS6 (Matriptase-2), belonging to TTSPs (transmembrane serine protease). TMPRSS6, is a type II TTSP, the genetic reduction of which will improve symptoms of hemochromatosis and beta thalassemia in mice .
Cat. No.: HY-13512R
CAS No.: 59721-29-8
Synonyms: Camostat mesilate (Standard); FOY305 (Standard); FOY-S980 (Standard)
Cat. No.: HY-114363
CAS No.: 1832686-43-7
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SRI 31215 is a Matriptase/Hepsin/hepatocyte growth factor activator (HGFA) triplex inhibitor and mimics the activity of HAI-1/2 (endogenous inhibitors of HGF activation). SRI 31215 has potent inhibitory activity against matriptase, hepsin and HGFA with IC50 values of 0.69 μM, 0.65 μM and 0.30 μM, respectively. SRI 31215 can be used for the research of cancer .
Cat. No.: HY-130136
CAS No.: 2088415-78-3
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TMPRSS6-IN-1 (compound 8) is a potent inhibitor of TMPRSS6 (Matriptase-2), belonging to TTSPs (transmembrane serine protease). TMPRSS6, is a type II TTSP, the genetic reduction of which will improve symptoms of hemochromatosis and beta thalassemia in mice .
Cat. No.: HY-RS17968
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St14 Mouse Pre-designed siRNA Set A contains three designed siRNAs for St14 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P11260
CAS No.: 3051556-89-6
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Cat. No.: HY-161370
CAS No.: 2574390-19-3
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VD4162 (Compound 8b) is a macrocyclic inhibitor of serine proteases. VD4162 can significantly improve potency for all four target enzymes TMPRSS2 (IC50 = 3.7 nM), HGFA(IC50 = 3.3 nM), matriptase (IC50 = 2.9 nM), and hepsin (IC50 = 0.54 nM). VD4162 can be used for the research of cancer .
Cat. No.: HY-P990464
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Cat. No.: HY-161371
CAS No.: 3058672-63-9
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VD5123 is a serine protease inhibitor. VD5123 inhibits TMPRS2, HGFA, matriptase, hepsin with IC50s of 15, 3980, 140, 37 nM respectively. VD5123 can be used for antiviral research, such as SARS-CoV-2 and broad panel of coronaviruses and influenza viruses .
Cat. No.: HY-161902
CAS No.: 3033379-90-4
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MI-1904 is the inhibitor for matriptase/TMPRSS2, that exhibits antiviral activity against influenza virus H1N1 and H9N2. MI-1904 blocks the cleavage of glycoproteins on the viral surface, prevents the virus from binding to host cell receptors, and thus inhibits the entry and replication of the virus .
Cat. No.: HY-145263
CAS No.: 2574389-19-6
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VD2173 is a side chain cyclized macrocyclic peptide inhibitor of HGF-activating serine proteases. VD2173 potently inhibits matriptase and hepsin. VD2173 can be used for the research of lung cancer .
Cat. No.: HY-180353
CAS No.: 51119-76-7
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Sodium 3-iodobenzenesulfonate (Compound 5) is an intermediate. Sodium 3-iodobenzenesulfonate Sodium 3-iodobenzenesulfonate can be used to synthesize 3-amidinophenylalanine-derived Matriptase inhibitors. Sodium 3-iodobenzenesulfonate can be used in the research of H9N2 influenza virus .
Cat. No.: HY-P992451
Synonyms: KY1066
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Cat. No.: HY-P704778
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: EC 3.4.21; Epithin; HAI; matriptase; Membrane-type serine protease 1; MTSP1; MT-SP1EC 3.4.21.109; prostamin; PRSS14; Serine protease 14; Serine protease TADG-15; SNC19; SNC19MTSP1; ST14; suppressor of tumorigenicity 14 protein; TADG15; TADG-15; TMPRSS14; tumor associated differentially expressed gene 15 protein; Tumor-associated differentially-expressed gene 15 protein
Cat. No.: HY-P702524
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: EC 3.4.21; Epithin; HAI; matriptase; Membrane-type serine protease 1; MTSP1; MT-SP1EC 3.4.21.109; prostamin; PRSS14; Serine protease 14; Serine protease TADG-15; SNC19; SNC19MTSP1; ST14; suppressor of tumorigenicity 14 protein; TADG15; TADG-15; TMPRSS14; tumor associated differentially expressed gene 15 protein; Tumor-associated differentially-expressed gene 15 protein
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
