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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
9 Results for "
mesoderm
" in MedChemExpress (MCE) Product Catalog:
Products (9)
9 Results for "mesoderm" in MCE Product Catalog:
1
1 Cited Publications
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Mesendogen is a TRPM6 inhibitor. Mesendogen enhances the mesoderm and definitive endoderm (DE) differentiations of human embryonic stem cells (hESCs) and human induced pluripotent stem cells (hiPSCs). Mesendogen can be used for the research of magnesium homeostasis during early embryonic cell development .
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IWP-3 is a Wnt production inhibitor with an IC50 of 40 nM. IWP-3 also acts as a CK1δ inhibitor, with an IC50 of 1.89 μM against rat full-length CK1δ. IWP-3 inhibits the function of Porcupine (Porcn), thereby blocking the palmitoylation of Wnt proteins, suppressing the canonical Wnt signaling pathway, reducing the proliferative capacity of cancer cells, promoting the differentiation of mesoderm into cardiomyocytes and increasing cardiomyocyte yield. IWP-3 reduces embryonic cell division, alters the cell movement along the anterior-posterior axis of embryos, and causes embryonic shortening. IWP-3 can be used in studies related to cancers such as pancreatic cancer .
Cat. No.: HY-137063
CAS No.: 1409968-46-2
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(+)-ITD-1 is an inhibitor for TGF-β, that inhibits the TGF-β2 with an IC50 of 0.46 μM. (+)-ITD-1 promotes the degradation of TGF-b type II receptor (TGFBR2) and the differentiation of cardiomyocyte, and inhibits the mesoderm formation in the early differentiation stage of mouse embryonic stem cells (mESCs) .
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VUT-MK142 is a cardiomyogenic small molecule. VUT-MK142 upregulates the expression of the myocardial marker ANF and other myocardial markers. VUT-MK142 promotes the development of cardiovascular progenitor cells into beating cardiomyocytes, and facilitates the differentiation of cardiac anterior mesoderm into cardiomyocytes. VUT-MK142 can be used in the research of heart failure .
Cat. No.: HY-174582
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Human MESP1 mRNA encodes the human Mesoderm posterior bHLH transcription factor 1 (MESP1) protein, a member of transcription factor which plays a role in the epithelialization of somitic mesoderm and in the development of cardiac mesoderm.
Cat. No.: HY-174712
Human FGF1 mRNA encodes the human Fibroblast growth factor 1 (FGF1) protein, a member of fibroblast growth factor (FGF) family. FGF1 functions as a modifier of endothelial cell migration and proliferation, as well as an angiogenic factor. It also acts as a mitogen for a variety of mesoderm- and neuroectoderm-derived cells in vitro, thus is thought to be involved in organogenesis.
Cat. No.: HY-103073R
CAS No.: 864716-85-8
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Mesendogen (Standard) is the analytical standard of Mesendogen (HY-103073). This product is intended for research and analytical applications. Mesendogen is a TRPM6 inhibitor. Mesendogen enhances the mesoderm and definitive endoderm (DE) differentiations of human embryonic stem cells (hESCs) and human induced pluripotent stem cells (hiPSCs). Mesendogen can be used for the research of magnesium homeostasis during early embryonic cell development .
Cat. No.: HY-12299G
CAS No.: 837422-57-8
Synonyms: Dual LCK/SRC inhibitor (GMP)
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
