127 Results for "

metabolic intermediate

" in MedChemExpress (MCE) Product Catalog:
Products (127)

127 Results for "metabolic intermediate" in MCE Product Catalog:

20
SAH
SAH
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20 Publications Verification
Cat. No.: HY-19528
CAS No.: 979-92-0
Synonyms: SAH (S-Adenosylhomocysteine)
Category:  

Human Gut Microbiota Metabolites Microorganisms Disease markers Metabolic Disease Amino acids Nervous System Disorder Endogenous metabolite Disease Research Fields

Target:  

Endogenous Metabolite

SAH (S-Adenosylhomocysteine) is an amino acid derivative and a modulartor in several metabolic pathways. It is an intermediate in the synthesis of cysteine and adenosine . SAH is an inhibitor for METTL3-METTL14 heterodimer complex (METTL3-14) with an IC50 of 0.9 µM .
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7
Acetyl Coenzyme A trisodium
Acetyl Coenzyme A trisodium
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7 Cited Publications
Cat. No.: HY-113596
CAS No.: 102029-73-2
Pureté:  99.22%
Synonyms: Acetyl-CoA trisodium
Category:  

Natural Products Metabolic Disease Endogenous metabolite Disease Research Fields

Target:  

Oxidative Phosphorylation Endogenous Metabolite Autophagy

Acetyl-coenzyme A (Acetyl-CoA) trisodium is a membrane-impermeant central metabolic intermediate, participates in the TCA cycle and oxidative phosphorylation metabolism. Acetyl-coenzyme A trisodium, regulates various cellular mechanisms by providing (sole donor) acetyl groups to target amino acid residues for post-translational acetylation reactions of proteins. Acetyl Coenzyme A trisodium is also a key precursor of lipid synthesis .
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7
Acetyl coenzyme A lithium
Acetyl coenzyme A lithium
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7 Cited Publications
Cat. No.: HY-113596A
CAS No.: 32140-51-5
Pureté:  97%
Synonyms: Acetyl-CoA lithium
Acetyl-coenzyme A (Acetyl-CoA) lithium is a membrane-impermeant central metabolic intermediate, participates in the TCA cycle and oxidative phosphorylation metabolism. Acetyl-coenzyme A lithium, regulates various cellular mechanisms by providing (sole donor) acetyl groups to target amino acid residues for post-translational acetylation reactions of proteins. Acetyl Coenzyme A lithium is also a key precursor of lipid synthesis .
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5
Succinyl-Coenzyme A sodium
Succinyl-Coenzyme A sodium
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5 Cited Publications
Cat. No.: HY-137808
CAS No.: 108347-97-3
Pureté:  94%
Synonyms: Succinyl-CoA sodium
Category:  

Natural Products Neurological Disease Metabolic Disease Endogenous metabolite Disease Research Fields

Target:  

Endogenous Metabolite

Succinyl CoA (Succinyl-coenzyme A) sodium is a pivotal intermediate metabolite in the tricarboxylic acid cycle and a key coenzyme A metabolite. Succinyl CoA sodium is biosynthesized from α-ketoglutarate or propionyl-CoA. Succinyl CoA sodium acts as a critical precursor and substrate for heme biosynthesis and gluconeogenesis. Succinyl CoA sodium insufficiency caused by cobalamin deficiency is directly linked to growth retardation, impaired heme synthesis, tissue glycine accumulation and neurological abnormalities. Succinyl CoA sodium can be used in research on metabolic, neurological, and hematological abnormalities (such as porphyria) caused by nutritional vitamin B12 deficiency (leading to a lack of Succinyl-Coenzyme A synthesis) .
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3
Shikimic acid
Shikimic acid
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3 Cited Publications
Cat. No.: HY-N0130
CAS No.: 138-59-0
Category:  

Microorganisms Ketones, Aldehydes, Acids Other Diseases Plants Acacia confusa Merr. Compositae Endogenous metabolite Disease Research Fields

Target:  

Endogenous Metabolite

Shikimic acid is a key metabolic intermediate of the aromatic amino acid biosynthesis pathway, found in microbes and plants.
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2
Oxaloacetic acid
Oxaloacetic acid
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2 Cited Publications
Cat. No.: HY-W010382
CAS No.: 328-42-7
Synonyms: 2-Oxosuccinic acid
Category:  

Human Gut Microbiota Metabolites Microorganisms Other disease Anti-aging Ketones, Aldehydes, Acids Disease markers Metabolic Disease Endogenous metabolite Disease Research Fields

Target:  

Endogenous Metabolite Reactive Oxygen Species (ROS)

Oxaloacetic acid (2-Oxosuccinic acid) is a metabolic intermediate involved in several ways, such as citric acid cycle, gluconeogenesis, the urea cycle, the glyoxylate cycle, amino acid synthesis, and fatty acid synthesis, whereby Oxaloacetic acid facilitates the clearance of reactive oxygen species (ROS) and improves mitochondrial function .
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1
Argininosuccinic acid disodium
Argininosuccinic acid disodium
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1 Cited Publications
Cat. No.: HY-113149A
CAS No.: 918149-29-8
Pureté:  96.93%
Category:  

Ketones, Aldehydes, Acids Endogenous metabolite Disease Research Fields Inflammation/Immunology

Target:  

Endogenous Metabolite Reactive Oxygen Species (ROS)

Argininosuccinic acid disodium is an intermediate metabolite in the urea cycle, and its level is associated with argininosuccinic aciduria. Argininosuccinic acid disodium can induce oxidative stress, leading to lipid and protein oxidation, reduction of glutathione, and decrease in antioxidant enzyme activity. Argininosuccinic acid disodium can be converted into guanidinosuccinic acid, a nitric oxide mimic, under the action of nitric oxide-derived free radicals. Argininosuccinic acid disodium can be used in the research of metabolic diseases, renal failure, nervous system diseases, etc .
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1
Farnesyl pyrophosphate ammonium
Farnesyl pyrophosphate ammonium
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1 Cited Publications
Cat. No.: HY-113037C
CAS No.: 116057-57-9
Pureté:  ≥95.0%
Synonyms: Farnesyl diphosphate ammonium
Category:  

Natural Products Neurological Disease Endogenous metabolite Disease Research Fields

Target:  

TRP Channel Endogenous Metabolite Calcium Channel

Farnesyl pyrophosphate (Farnesyl diphosphate) ammonium is a metabolic intermediate in the mevalonate (MVA) pathway. It is a TRP channel (TRPM2) agonist that triggers Ca2+ influx and cell death. Farnesyl pyrophosphate ammonium is a key branch substrate for cholesterol synthesis, ubiquinone synthesis, protein farnesylation, and geranylgeranyl pyrophosphate (GGPP) synthesis. Farnesyl pyrophosphate ammonium is used in research on cerebral ischemia, neurodegenerative diseases, pancreatic cancer, inflammation, and autoimmune diseases .
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1
2-Hydroxypalmitic acid
2-Hydroxypalmitic acid
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1 Cited Publications
Cat. No.: HY-N7814
CAS No.: 764-67-0
Category:  

Microorganisms Ketones, Aldehydes, Acids Other Diseases Disease Research Fields

Target:  

Endogenous Metabolite Drug Intermediate

2-Hydroxypalmitic acid is an intermediate in the phytosphingosine metabolic pathway. 2-Hydroxypalmitic acid is exclusively incorporated into sphingolipids and not used for other lipids. 2-Hydroxypalmitic acid promotes the production of odd-carbon phosphatidylcholine species. 2-Hydroxypalmitic acid is applicable to studies of Saccharomyces cerevisiae infection .
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1
2,3-Oxidosqualene
2,3-Oxidosqualene
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1 Cited Publications
Cat. No.: HY-114296
CAS No.: 7200-26-2
Synonyms: Squalene oxide
Target:  

Drug Intermediate Endogenous Metabolite

Domaines de recherche:  

Others

2,3-Oxidosqualene (Squalene oxide) is a sterol biosynthesis precursor intermediate.2,3-Oxidosqualene participates in cyclization pathways that form sterols and triterpenes, and contributes to introduction of their characteristic 3-hydroxyl group.2,3-Oxidosqualene forms metabolically from squalene in rat liver homogenates under sterol synthesis conditions.2,3-Oxidosqualene converts to sterols including cholesterol, lathosterol, and lanost-8-en-3β-ol in rat liver homogenates under anaerobic conditions .
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1
Dephospho-CoA
Dephospho-CoA
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1 Cited Publications
Cat. No.: HY-137899
CAS No.: 3633-59-8
Pureté:  96.00%
Category:  

Human Gut Microbiota Metabolites Natural Products Other Diseases Endogenous metabolite Disease Research Fields

Target:  

Endogenous Metabolite

Dephospho-CoA is a key intermediate in the biosynthesis of coenzyme A (CoA), which is catalyzed to form CoA by GTP-dependent Dephospho-CoA kinase (DPCK). Dephospho-CoA completes the final synthetic step of CoA via phosphorylation and participates in energy metabolism and cellular signal transduction. Dephospho-CoA can be used in studies involving cancer (e.g., regulation of cell proliferation) and metabolic diseases (e.g., mitochondrial dysfunction) .
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1
D-Fructose 1-phosphate disodium
D-Fructose 1-phosphate disodium
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1 Cited Publications
Cat. No.: HY-112253A
CAS No.: 71662-09-4
Category:  

Human Gut Microbiota Metabolites Natural Products Other Diseases Endogenous metabolite Disease Research Fields

Target:  

Endogenous Metabolite

D-Fructose 1-phosphate disodium is a key intermediate metabolite in the fructose metabolic pathway. As a key signaling molecule linking fructose metabolism and glucose metabolic regulation, D-Fructose 1-phosphate disodium acts as an allosteric modulator to counteract the inhibitory effect of the glucokinase-regulatory protein complex, thereby finely regulating the direction of hepatic glucose metabolism at the substrate level .
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1
Oxaloacetic acid-13C4
Oxaloacetic acid-13C4
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1 Cited Publications
Cat. No.: HY-W010382S
CAS No.: 161096-82-8
Synonyms: 2-Oxosuccinic acid-13C4
Oxaloacetic acid- 13C4 is the 13C-labeled Oxaloacetic acid. Oxaloacetic acid (2-Oxosuccinic acid) is a metabolic intermediate involved in several ways, such as citric acid cycle, gluconeogenesis, the urea cycle, the glyoxylate cycle, amino acid synthesis, and fatty acid synthesis .
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1
3-Indoleacetic acid,suitable for plant cell culture
3-Indoleacetic acid,suitable for plant cell culture
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1 Cited Publications
Cat. No.: HY-18569B
CAS No.: 87-51-4
Synonyms: IAA
3-Indoleacetic acid, suitable for plant cell culture (IAA), is a naturally occurring plant growth hormone that is widely present in plants, bacteria, and fungi. 3-Indoleacetic acid, suitable for plant cell culture, is a plant growth-promoting hormone that not only promotes plant growth but also protects bacteria from the toxic damage to cell membrane potential caused by other indole intermediate products (such as I3P) produced during their own metabolic processes. 3-Indoleacetic acid, suitable for plant cell culture, can be used in plant cell culture .
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1
N-Carbamoyl-L-aspartic acid
N-Carbamoyl-L-aspartic acid
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1 Cited Publications
Cat. No.: HY-128425A
CAS No.: 13184-27-5
Pureté:  ≥98.0%
Synonyms: L-Ureidosuccinic acid
Category:  

Natural Products Other Diseases Endogenous metabolite Disease Research Fields

Target:  

Fungal

N-Carbamoyl-L-aspartic acid (L-Ureidosuccinic acid) is an important pyrimidine metabolic precursor and intermediate metabolite. N-Carbamoyl-L-aspartic acid reverses the growth inhibition of Ura + strains induced by 2-thiouracil (with growth rate increasing linearly with its concentration), but fails to support the growth of uracil-requiring Ura - strains. N-Carbamoyl-L-aspartic acid inhibits the cell growth of *Saccharomyces cerevisiae* by suppressing the purine biosynthetic pathway at a pre-step of 5-aminoimidazole nucleotide synthesis. The growth inhibitory effect of N-Carbamoyl-L-aspartic acid on yeast can be alleviated by purines, and the sensitivity of strains is closely related to the activity level of dihydroorotase .
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Dodecanoylcarnitine
Dodecanoylcarnitine
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1 Cited Publications
Cat. No.: HY-113166
CAS No.: 25518-54-1
Pureté:  99.75%
Synonyms: (-)-Lauroylcarnitine
Category:  

Immune System Disorder Ketones, Aldehydes, Acids Disease markers Metabolic Disease Endocrine diseases Endogenous metabolite Disease Research Fields

Target:  

Endogenous Metabolite

Dodecanoylcarnitine ((-)-Lauroylcarnitine) is a medium long-chain acylcarnitine, an intermediate product in key energy metabolic pathways of fatty acid β-oxidation and amino acids catabolism. The abnormal decrease in the Dodecanoylcarnitine levels indicats that mitochondrial fuel metabolism, including fatty acid oxidation is significantly disturbed. Changes in plasma concentrations of Dodecanoylcarnitine are not only associated with type II diabetes, but also with pre-diabetes status. Dodecanoylcarnitine is present in fatty acid oxidation disorders such as long-chain acyl CoA dehydrogenase deficiency, carnitine palmitoyltransferase I/II deficiency, and is also associated with celiac disease. Dodecanoylcarnitine deomonstrates high sensitivities and specificities in predicting asthma. Combined model of Decanoylcarnitine (HY-113069), Dodecanoylcarnitine, PC (16:0/0:0), and Asp Arg Pro can be used as a potential biomarker for the diagnosis of Yin-deficiency-heat syndrome .
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3-Phosphoglyceric acid
3-Phosphoglyceric acid
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Cat. No.: HY-113491
CAS No.: 820-11-1
Pureté:  99.88%
Synonyms: 3-PGA; 3-Glycerophosphoric acid
Category:  

Human Gut Microbiota Metabolites Microorganisms Ketones, Aldehydes, Acids Endogenous metabolite

Target:  

Endogenous Metabolite

3-Phosphoglyceric acid is a metabolic intermediate in both glycolysis and the Calvin cycle. 3-Phosphoglyceric acid is involved in alveolar macrophage epigenetic regulation.
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D-(+)-Cellobiose
D-(+)-Cellobiose
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Cat. No.: HY-N2325
CAS No.: 528-50-7
Category:  

Human Gut Microbiota Metabolites Polysaccharides Microorganisms Metabolic Disease Endogenous metabolite Disease Research Fields Saccharides

Target:  

Endogenous Metabolite

D-(+)-Cellobiose is a water-soluble disaccharide and an important intermediate product in the degradation process of cellulose and hemicellulose. D-(+)-cellobiose is used as a carbon source by microorganisms in fermentation processes, where it is converted into ethanol or other metabolic products. D-(+)-Cellobiose has significant application value in biofuel production, such as bioethanol .
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Geranylgeranyl pyrophosphate triammonium
Geranylgeranyl pyrophosphate triammonium
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Cat. No.: HY-126370A
CAS No.: 313263-08-0
Pureté:  ≥95.0%
Category:  

Natural Products Endogenous metabolite Disease Research Fields Cancer

Target:  

Endogenous Metabolite YAP Apoptosis Interleukin Related STAT ERK Ras

Geranylgeranyl pyrophosphate triammonium is a type of isoprenoid metabolic intermediate, mainly synthesized through the mevalonate pathway. Geranylgeranyl pyrophosphate triammonium is a key precursor in various biological synthesis processes, especially as a necessary substrate for post-translational modification of proteins - geranylgeranyl phosphorylation. Geranylgeranyl pyrophosphate triammonium regulates various cellular processes and disease progression through protein geranylgeranyl phosphorylation, such as activating the YAP signaling pathway, promoting cell proliferation and inhibiting apoptosis; promoting IL-2 production and STAT5 phosphorylation; and influencing metabolic homeostasis and cancer, etc .
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Dihydroxyacetone phosphate
Dihydroxyacetone phosphate
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Cat. No.: HY-113131
CAS No.: 57-04-5
Pureté:  99.90%
Synonyms: DHAP
Category:  

Human Gut Microbiota Metabolites Microorganisms Ketones, Aldehydes, Acids Metabolic Disease Endogenous metabolite Disease Research Fields

Target:  

Endogenous Metabolite Biochemical Assay Reagents

Dihydroxyacetone phosphate (DHPA), a derivative of Dihydroxyacetone (DHA), is an important intermediate that participates in key pathways including glycolysis, lipid biosynthesis, and the plant Calvin cycle. Dihydroxyacetone phosphate can be used as a substrate and metabolic marker in biochemical research .
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