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Results for "

mouse DP

" in MedChemExpress (MCE) Product Catalog:

12

Inhibitors & Agonists

2

Inhibitory Antibodies

1

Recombinant Proteins

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-10418
    AH 6809
    4 Publications Verification

    		 Prostaglandin Receptor Inflammation/Immunology Endocrinology
    AH 6809 is an antagonist of EP and DP receptor, with Kis of 1217, 1150, 1597, and 1415 nM for the cloned human EP1, EP2, EP3-III, and DP receptor respectively. AH 6809 has a Ki of 350 nM for mouse EP2 receptor .
    AH 6809
  • HY-168936
    DP-15

    		PROTACs Epigenetic Reader Domain Apoptosis Cancer
    DP-15 is the degrader for GSPT1 and BRD4 with DC50s of 5.25 nM and 0.48 nM. DP-15 exhibits anti-proliferative activity of AML cells and NHL cells with an IC50 of nanomolar levels, arrests the cell cycle at G1 phase, and induces apoptosis in MOLM13. DP-15 exhibits anti-leukemia activity in MOLM-13 xenograft mouse models . (Pink: ligand for target protein JQ-1 carboxylic acid (HY-78695); Black: linker (HY-W262798); Blue: ligand for E3 ligase Cereblon Thalidomide-5-OH (HY-23095))
    DP-15
  • HY-13213
    AM211

    AM211 free acid

    		 Prostaglandin Receptor Inflammation/Immunology Endocrinology
    AM211 is a potent, selective and orally bioavailable prostaglandin D2 (PGD2) receptor type 2 (DP2) antagonist, with IC50s of 4.9 nM, 7.8 nM, 4.9 nM, 10.4 nM for human, mouse, guinea pig, and rat DP2, respectively.
    AM211
  • HY-13706
    CAY10471 Racemate

    TM30089 Racemate

    		 Prostaglandin Receptor Endocrinology Cancer
    CAY10471 Racemate (TM30089 Racemate) is a potent and highly selective prostaglandin D2 receptor CRTH2 antagonist, with a Ki of 0.6 nM for hCRTH2, selective over human thromboxane A2 receptor TP (Ki, >10000 nM) or PGD2 receptor DP (Ki, 1200 nM). CAY10471 Racemate also has effect on mouse and rat orthologs of CRTH2 .
    CAY10471 Racemate
  • HY-122558
    AM432 sodium

    		Prostaglandin Receptor Neurological Disease
    AM432 (sodium) is a potent and selective antagonist of the DP2 receptor (CRTH2). AM432 (sodium) exhibits excellent potency in a human whole blood eosinophil shape change assay with prolonged incubation. AM432 (sodium) also demonstrates excellent pharmacokinetics in dog and mouse models of inflammatory disease .
    AM432 sodium
  • HY-P991750
    Anti-pan MHC Class II (HLA II) Antibody (IVA12)

    		MHC Inflammation/Immunology
    Anti-pan MHC Class II (HLA II) Antibody (IVA12) recognizes human HLA-II (HLA-DR, HLA-DP, and HLA-DQ). Anti-pan MHC Class II (HLA II) Antibody (IVA12) blocks MHC-II in vitro. Recommend Isotype Controls: Mouse IgG1 kappa, Isotype Control (HY-P99977) .
    Anti-pan MHC Class II (HLA II) Antibody (IVA12)
  • HY-114623
    Prostaglandin D2 methyl ester

    		Prostaglandin Receptor Inflammation/Immunology
    Prostaglandin D2 methyl ester is a prodrug form of Prostaglandin D2 (HY-101988) that acts as a DP receptor inhibitor. can be used for research on allergic inflammations .
    Prostaglandin D2 methyl ester
  • HY-117862
    TASP0412098

    		Prostaglandin Receptor Inflammation/Immunology
    TASP0412098 is an orally available, potent and selective CRTH2/DP2 antagonist with high binding affinity (IC50 2.1 nM) and functional activity (IC50 12 nM). TASP0412098 has the potential to suppress asthma in mouse and guinea pig bronchial asthma models .
    TASP0412098
  • HY-10418R
    AH 6809 (Standard)

    		Reference Standards Prostaglandin Receptor Inflammation/Immunology Endocrinology
    AH 6809 (Standard) is the analytical standard of AH 6809. This product is intended for research and analytical applications. AH 6809 is an antagonist of EP and DP receptor, with Kis of 1217, 1150, 1597, and 1415 nM for the cloned human EP1, EP2, EP3-III, and DP receptor respectively. AH 6809 has a Ki of 350 nM for mouse EP2 receptor .
    AH 6809 (Standard)
  • HY-P991837
    Anti-HLA-DP Antibody (B7/21)

    		CD74 Inflammation/Immunology
    Anti-HLA-DP Antibody (B7/21) reacts with the class II major histocompatibility complex (MHC) antigen. Anti-HLA-DP Antibody (B7/21) recognizes a monomorphic determinant present on cells expressing DP1, DP2, DP3, DP4 and DP5. Recommend Isotype Controls: Mouse IgG3 kappa, Isotype Control (HY-P99985) .
    Anti-HLA-DP Antibody (B7/21)
  • HY-13213A
    AM211 sodium

    		Prostaglandin Receptor Inflammation/Immunology Endocrinology
    AM211 sodium is a potent, selective and orally bioavailable prostaglandin D2 (PGD2) receptor type 2 (DP2) antagonist, with IC50s of 4.9 nM, 7.8 nM, 4.9 nM, 10.4 nM for human, mouse, guinea pig, and rat DP2, respectively.
    AM211 sodium
  • HY-160844
    CT-133

    		Prostaglandin Receptor TNF Receptor Interleukin Related Inflammation/Immunology
    CT-133 is a selective and potent CRTH2 Receptor antagonist, with a Ki value of 2.2 nM. The Ki value for the DP1 receptor is greater than 3800 nM. CT-133 inhibits neutrophil migration induced by PGD2 (HY-101988). CT-133 significantly alleviates lung inflammation and improves lung function impairment in a mouse model of acute lung injury (ALI) induced by cigarette smoke. CT-133 effectively inhibits the excessive expression of pro-inflammatory cytokines (TNF-α, IL-1β, and IL-6) and chemokines (KC), and reverses the inhibition of the anti-inflammatory factor IL-10. CT-133 can be used for the study of ALI .
    CT-133

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