Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
24 Results for "
neuron-specific
" in MedChemExpress (MCE) Product Catalog:
Products (24)
24 Results for "neuron-specific" in MCE Product Catalog:
2
2 Cited Publications
Target:
Research Areas:
CLP290 is an orally available activator of the neuron-specific K +-Cl - cotransporter KCC2, displays potential for treatment of a wide range of neurological and psychiatric indications. CLP290 can significantly lower blood arginine-vasopressin (AVP) and glucose levels in STZ (HY-13753) rats .
2
2 Cited Publications
Cat. No.: HY-P1241
CAS No.: 412961-36-5
Research Areas:
1
1 Cited Publications
Target:
Research Areas:
1
1 Cited Publications
Cat. No.: HY-P2862A
Target:
Research Areas:
Neuron-specific enolase, Human (EC 4.2.1.11), an enolase, is a biomarker in traumatic brain injury (TBI), stroke and anoxic encephalopathy after cardiac arrest and acute SCI as well .
Cat. No.: HY-108438
CAS No.: 1201916-31-5
Target:
Research Areas:
TCS 2210 (compound 1) is a neuronal differentiation inducer in mesenchymal stem cells (MSCs). TCS 2210 increases expression of the neuronal markers β-III tubulin and neuron-specific enolase (NSE) .
Cat. No.: HY-115606
CAS No.: 1135304-61-8
Target:
Research Areas:
ML007 is a selective antagonist targeting the neuron-specific potassium-chloride co-transporter 2 (KCC2) with an IC50 for KCC2 is 537 nM, while its inhibitory activity on KCC1 is extremely weak (IC50 > 50 μM). ML077 inhibits the chloride ion excretion function of KCC2, increasing the intracellular chloride ion concentration, thereby enhancing the depolarization mediated by chloride ion channels. ML007 can promote glucose-stimulated insulin secretion (GSIS) without relying on KATP channels. ML007 can be used to study the functions related to pain, epilepsy, and insulin secretion .
Cat. No.: HY-P1241A
Research Areas:
Cat. No.: HY-P706279
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: ¹⁵N-neuron-specific enolase; ¹⁵N-γ-Enolase; ¹⁵N-Enolase 2; ¹⁵N-2-Phosphoglycerate dehydratase; ENO2; Neural Enolase; Enolase 2; HEL-S-279; NSE; Epididymis Secretory Protein Li 279; 2-Phospho-D-Glycerate Hydro-Lyase; 2-Phospho-D-Glycerate Hydrolyase; Gamma-Enolase; neuron specific Gamma Enolase; Enolase 2 (Gamma, neuronal); Phosphopyruvate Hydratase; neuronal Enriched Enolase; neurone-specific Enolase; neuron-specific Enolase; neuron specific Enolase
Species:
Human
Source:
E. coli
Cat. No.: HY-103023R
CAS No.: 1181083-81-7
Target:
Research Areas:
CLP290 (Standard) is the analytical standard of CLP290 (HY-103023). This product is intended for research and analytical applications. CLP290 is an orally available activator of the neuron-specific K+-Cl- cotransporter KCC2, displays potential for treatment of a wide range of neurological and psychiatric indications. CLP290 can significantly lower blood arginine-vasopressin (AVP) and glucose levels in STZ (HY-13753) rats .
Cat. No.: HY-105066R
CAS No.: 211439-12-2
Research Areas:
- 1
- 2
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
