20 Results for "

nicotinic acid derivatives

" in MedChemExpress (MCE) Product Catalog:
Products (20)

20 Results for "nicotinic acid derivatives" in MCE Product Catalog:

4
4 Cited Publications
Cat. No.: HY-126477
CAS No.: 64091-91-4
Purity:  99.98%
NNK is a nicotine-nitrosated derivative. NNK simultaneously stimulates Bcl2 phosphorylation exclusively at Ser 70 and c-Myc at Thr 58 and Ser 62 through activation of both ERK1/2 and PKCα . NNK induces survival and proliferation of human lung cancer cells. NNK can be used for lung cancer mice model structure .
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Cat. No.: HY-101701
CAS No.: 7237-81-2
Purity:  98.41%
Synonyms: Megrin
Target:  

Drug Derivative

Research Areas:  

Cardiovascular Disease

Hepronicate, a nicotinic acid derivative, is a peripheral vasodilator with blood lipid lowering action. Hepronicate works by improving peripheral circulatory disturbances .
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Cat. No.: HY-N8723
CAS No.: 51095-86-4
(1′S,2′S)-Nicotine-1'-oxide is a nicotine derivative and also a non/weakly potent α3β4 neuronal nicotinic acetylcholine receptor (nAChR) ligand .
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Cat. No.: HY-N3359
CAS No.: 550-90-3
Synonyms: D-Lupanine
Lupanine (D-Lupanine) is a natural ketonic derivative of Sparteine (HY-W008350) with a ganglioplegic activity. Lupanine shows binding affinity for nicotinic receptor with a Ki value of 500 nM .
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Cat. No.: HY-N8723S
(1′S,2′S)-Nicotine-1'-oxide-d3 is the d3-labeled (1′S,2′S)-Nicotine-1'-oxide (HY-N8723). (1′S,2′S)-Nicotine-1'-oxide is a nicotine derivative and also a non/weakly potent α3β4 neuronal nicotinic acetylcholine receptor (nAChR) ligand .
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Cat. No.: HY-W002323
CAS No.: 38496-18-3
Research Areas:  

Others

2,6-Dichloronicotinic acid is a nicotinic acid derivative. 2,6-Dichloronicotinic acid can serve as a biological material or organic compound for life science-related research .
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Cat. No.: HY-W012617
CAS No.: 553-53-7
Synonyms: nicotinic acid hydrazide
Target:  

Drug Intermediate

Research Areas:  

Infection

Nicotinohydrazide (Nicotinic acid hydrazide) is a precursor used for synthesizing hydrazone derivatives with antibacterial and antifungal activities. Nicotinohydrazide can be used in studies of bacterial and fungal infections .
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Cat. No.: HY-133027
CAS No.: 273203-62-6
Purity:  99.40%
Synonyms: Tetradecyl nicotinate
Research Areas:  

Cancer

Myristyl nicotinate (Tetradecyl nicotinate) is an ester proagent and a lipophilic derivative of Nicotinic acid. Myristyl nicotinate is being developed for delivery of Nicotinic acid into the skin for prevention of actinic keratosis and its progression to skin cancer. Myristyl nicotinate shows to stimulate epidermal differentiation in photodamaged skin, increasing skin NAD content and strengthening the skin barrier .
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Cat. No.: HY-W273281
CAS No.: 15658-35-2
Target:  

MOFs

Research Areas:  

Others

6,6′-Dithiodinicotinic acid is a sulfur-containing organic compound belonging to nicotinic acid derivatives, which can be used as a specific sulfhydryl blocker .
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Cat. No.: HY-N3359B
CAS No.: 1025-39-4
Synonyms: D-Lupanine hydrochloride
Lupanine (D-Lupanine) hydrochloride is a natural ketonic derivative of Sparteine (HY-W008350) with a ganglioplegic activity. Lupanine hydrochloride shows binding affinity for nicotinic receptor with a Ki value of 500 nM .
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Cat. No.: HY-Y1013
CAS No.: 20826-04-4
5-Bromonicotinic acid is a brominated pyridinecarboxylic acid derivative of nicotinic acid, which serves as a pharmaceutical intermediate for organic synthesis-related research. 5-Bromonicotinic acid can form metal-organic frameworks (MOFs) with cadmium (II), cobalt (II) and lanthanide (III) salts .
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Cat. No.: HY-178935
CAS No.: 1099611-82-1
α-Amylase-IN-14, a derivative of Nicotinic (HY-B0143), is an α-amylase inhibitor and has good interactions with α-amylase protein (-5.55 kcal/mol). α-Amylase-IN-14 is a dual anti-inflammatory and anti-hyperglycemic agent. α-Amylase-IN-14 exhibits good results against DPPH and ABTS radicals. α-Amylase-IN-14 can be used for the study of diabetes .
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Cat. No.: HY-106559
CAS No.: 6184-06-1
Target:  

GCGR

Research Areas:  

Cardiovascular Disease

Sorbinicate, a derivative of nicotinic acid, exerts a favourable influence on blood rheology and platelet function .
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Cat. No.: HY-N3359A
CAS No.: 7400-11-5
Synonyms: D-Lupanine perchlorate
Lupanine (D-Lupanine) perchlorate is a natural ketonic derivative of Sparteine (HY-W008350)with a ganglioplegic activity. Lupanine perchlorate shows binding affinity for nicotinic receptor with a Ki value of 500 nM .
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Cat. No.: HY-133027R
CAS No.: 273203-62-6
Synonyms: Tetradecyl nicotinate (Standard)
Research Areas:  

Cancer

Myristyl nicotinate (Standard) is the analytical standard of Myristyl nicotinate. This product is intended for research and analytical applications. Myristyl nicotinate (Tetradecyl nicotinate) is an ester proagent and a lipophilic derivative of Nicotinic acid. Myristyl nicotinate is being developed for delivery of Nicotinic acid into the skin for prevention of actinic keratosis and its progression to skin cancer. Myristyl nicotinate shows to stimulate epidermal differentiation in photodamaged skin, increasing skin NAD content and strengthening the skin barrier .
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Cat. No.: HY-161508
CAS No.: 3036136-22-5
Target:  

Cholinesterase (ChE)

Research Areas:  

Neurological Disease

AChE/BChE-IN-19 (Compound 12) is a nicotinic hydrazide derivative. AChE/BChE-IN-19 is a inhibitor of AChE (IC50 = 21.45 nM) and BChE (IC50 =18.42 nM). AChE/BChE-IN-19 can be used in Alzheimer's disease research .
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Cat. No.: HY-19013
CAS No.: 95240-93-0
Target:  

Drug Derivative

Research Areas:  

Cardiovascular Disease

L44-0 is a nicotinic acid derivative. L44-0 reduces atherosclerotic lesions and decreases vascular norepinephrine levels in the renal arteries, femoral arteries, and veins in a New Zealand white rabbit model of atherosclerosis. L44-0 can be used in research on cardiovascular and cerebrovascular diseases such as atherosclerosis .
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Cat. No.: HY-126477R
CAS No.: 64091-91-4
NNK (Standard) is the analytical standard of NNK. This product is intended for research and analytical applications. NNK is a nicotine-nitrosated derivative. NNK simultaneously stimulates Bcl2 phosphorylation exclusively at Ser70 and c-Myc at Thr58 and Ser62 through activation of both ERK1/2 and PKCα . NNK induces survival and proliferation of human lung cancer cells. NNK can be used for lung cancer mice model structure .
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Cat. No.: HY-Y1013R
CAS No.: 20826-04-4
5-Bromonicotinic acid (Standard) is the analytical standard of 5-Bromonicotinic acid (HY-Y1013). This product is intended for research and analytical applications. 5-Bromonicotinic acid is a brominated pyridinecarboxylic acid derivative of nicotinic acid, which serves as a pharmaceutical intermediate for organic synthesis-related research. 5-Bromonicotinic acid can form metal-organic frameworks (MOFs) with cadmium (II), cobalt (II) and lanthanide (III) salts .
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Cat. No.: HY-121102
CAS No.: 1257067-10-9
Carboetomidate is a pyrrole derivative analogous to the sedative-hypnotic drug Etomidate, which induces general anesthesia while avoiding the inhibition of adrenal steroid synthesis. Carboetomidate enhances GABAA receptor function via β2/β3 subunits, inhibits neuronal nicotinic acetylcholine receptors (nAChR) and 5-HT3A receptors, and increases plasma IL-10 levels during endotoxemia. Carboetomidate is applicable to research related to sepsis and sleep disorders .
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