50 Results for "

ntibiotic

" in MedChemExpress (MCE) Product Catalog:
Products (50)

50 Results for "ntibiotic" in MCE Product Catalog:

235
235 Publications Verification
Cat. No.: HY-15141
CAS No.: 62996-74-1
Purity:  99.52%
Synonyms: Antibiotic AM-2282; STS; AM-2282
Staurosporine is a potent, ATP-competitive and non-selective inhibitor of protein kinases with IC50s of 6 nM, 15 nM, 2 nM, and 3 nM for PKC, PKA, c-Fgr, and Phosphorylase kinase respectively. Staurosporine also inhibits TAOK2 with an IC50 of 3 μM. Staurosporine is an apoptosis inducer .
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71
71 Cited Publications
Cat. No.: HY-108718
CAS No.: 49863-47-0
Synonyms: Geneticin; Antibiotic G-418
Research Areas:  

Infection

G-418 (Geneticin) is an aminoglycoside antibiotic with a structure similar to gentamicin. It is toxic to both eukaryotic and prokaryotic cells and works by interfering with protein synthesis .
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27
27 Cited Publications
Cat. No.: HY-N6732
CAS No.: 99533-80-9
Synonyms: SF2370; Antibiotic K 252a; Antibiotic SF 2370
K-252a, a staurosporine analog, inhibits protein kinase, with IC50 values of 470 nM, 140 nM, 270 nM, and 1.7 nM for PKC, PKA, Ca 2+/calmodulin-dependent kinase type II, and phosphorylase kinase, respectively . K-252a is a potent inhibitor (IC50 of 3 nM) of the tyrosine protein kinase (TRK) activity of the NGF receptor gp140trk, the product of the trk protooncogene .
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26
26 Cited Publications
Cat. No.: HY-N6687
CAS No.: 52665-69-7
Synonyms: A-23187; Antibiotic A-23187
Calcimycin (A-23187) is an antibiotic and a unique divalent cation ionophore (like calcium and magnesium). Calcimycin induces Ca 2+-dependent cell death by increasing intracellular calcium concentration. Calcimycin inhibits the growth of Gram-positive bacteria and some fungi. Calcimycin also inhibits the activity of ATPase and uncouples oxidative phosphorylation (OXPHOS) of mammalian cells. Calcimycin induces apoptosis and autophagy .
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5
5 Cited Publications
Cat. No.: HY-B1222A
CAS No.: 32385-11-8
Synonyms: Antibiotic 6640; Rickamicin
Sisomicin is a broad-spectrum aminoglycoside antibiotic produced by Micromonospora inyoensis. Sisomicin is highly active against Gram-positive bacteria .
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4
4 Cited Publications
Cat. No.: HY-101938
CAS No.: 58944-73-3
Purity:  99.91%
Synonyms: Adenosyl-Ornithine; A-9145; Antibiotic 32232RP
Sinefungin is a potent inhibitor of virion mRNA(guanine-7-)-methyltransferase, mRNA(nucleoside-2'-)-methyltransferase, and viral multiplication . Sinefungin, a SET7/9 inhibitor, ameliorates renal fibrosis by inhibiting H3K4 methylation .
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4
4 Cited Publications
Cat. No.: HY-12820
CAS No.: 1616113-45-1
Purity:  99.70%
Synonyms: Antibiotic-202
Target:  

Bacterial Antibiotic

Research Areas:  

Infection

Sibofimloc (Antibiotic-202) is a first-in-class, gut-restricted, orally active FimH adhesion inhibitor extracted from patent WO2014100158A1, Compound Example 202. Sibofimloc has anti-bacterial infective activity. Sibofimloc is developed for inflammatory bowel disease (IBD) .
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2
2 Cited Publications
Cat. No.: HY-B1908
CAS No.: 35457-80-8
Synonyms: SF-837; Antibiotic SF-837
Midecamycin, an acetoxy-substituted macrolide antibiotic, is tested against gram-positive and gram-negative bacteria.
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1
1 Cited Publications
Cat. No.: HY-A0097
CAS No.: 61036-62-2
Synonyms: Antibiotic MDL-507; MDL-507
Teicoplanin is a glycopeptide antibiotic indicated for use in serious infections caused by Gram-positive bacteria, including Methicillin-resistant Staphylococcus aureus and Enterococcus aureus.Teicoplanin shows antiviral activity for HIV-1, SARS-CoV1 and SARS-CoV2. Teicoplanin sodium shows anti-MRSA activity .
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Cat. No.: HY-100833
CAS No.: 251349-54-9
Purity:  99.71%
Target:  

Bacterial Antibiotic

Research Areas:  

Infection

Antibiotic-5d is a synthesis and antimicrobial compound.
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Cat. No.: HY-19965
CAS No.: 167173-85-5
Synonyms: Antibiotic UK 2A
UK-2A (Antibiotic UK 2A) is a potent antifungal antibiotic. UK-2A shows antifungal activity .
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Cat. No.: HY-121405
CAS No.: 38249-71-7
Synonyms: Antibiotic K16
Target:  

Antibiotic Parasite

Research Areas:  

Infection

Malonomicin (Antibiotic K16) is an antibiotic with anti-protozoa and anti-trypanosome activities. Malonomicin also shows anti-trypanosome activity in vivo .
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Cat. No.: HY-103397A
CAS No.: 98392-26-8
Purity:  99.14%
Synonyms: Antibiotic YS-02931K-β
Research Areas:  

Infection

Dihydrokalafungin (Antibiotic YS-02931K-β) is a benzoisochromanequinone that used as a natural substrate in enzyme assays of the ActVB-ActVA system .
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Cat. No.: HY-178949
Research Areas:  

Infection

MRSA antibiotic 3 (Compound C8) is a small-molecule antibiotic active against Methicillin (HY-121544)-resistant Staphylococcus aureus (MRSA), showing a MIC of 0.5 μg/mL against the standard S. aureus strain (ATCC 29213). MRSA antibiotic 3 potently inhibits the ATPase activity of S. aureus DNA gyrase with an IC50 of 0.32 μM. MRSA antibiotic 3 exhibits strong inhibitory activity against five clinical MRSA isolates, with MIC values ranging from 0.5 to 1 μg/mL. MRSA antibiotic 3 demonstrates negligible cytotoxicity at effective antibacterial concentrations and causes no hemolysis in erythrocytes even at extremely high concentrations. MRSA antibiotic 3 shows significant protective effects in both Galleria mellonella infection and murine sepsis models .
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Cat. No.: HY-120333
CAS No.: 147317-15-5
Antibiotic PF 1052 is an antibiotic extracted from a natural product library. Antibiotic PF 1052 has an inhibitory effect on murine neutrophil migration .
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Cat. No.: HY-P2450
CAS No.: 76600-38-9
Synonyms: Antibiotic P168
Leucinostatin A (Antibiotic P168) is a nonapeptide exerting a remarkable activity especially against Candida albicans and Cryptococcus neoformans. Leucinostatin A is a hydrophobic nonapeptide antibiotic. Leucinostatin A inhibits prostate cancer growth through reduction of insulin-like growth factor-I expression in prostate stromal cells. Antiprotozoal activies .
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Cat. No.: HY-A0097A
CAS No.: 184539-13-7
Synonyms: Antibiotic MDL-507 sodium; MDL-507 sodium
Teicoplanin sodium is a glycopeptide antibiotic indicated for use in serious infections caused by Gram-positive bacteria, including Methicillin-resistant Staphylococcus aureus and Enterococcus aureus.Teicoplanin sodium shows antiviral activity for HIV-1, SARS-CoV1 and SARS-CoV2. Teicoplanin sodium shows anti-MRSA activity .
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Cat. No.: HY-112661
CAS No.: 108375-77-5
Synonyms: Antibiotic PC-766B
PC-766B is a macrolide antibiotic. PC-766B is active against Gram-positive bacteria, and some fungi and yeasts, but inactive against Gram-negative bacteria. PC-766B shows antitumor activity against murine tumor cells. PC-766B has weak inhibitory activity against Na +, K +-ATPase .
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Cat. No.: HY-113602
CAS No.: 101411-71-6
Synonyms: Antibiotic 273 A1-beta
Target:  

Antibiotic Bacterial

Research Areas:  

Infection

Paldimycin B (Antibiotic 273 A1-beta) is a powerful semi-synthetic antibiotic with antibacterial activity against S. aureus and coagulase-negative staphylococci .
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Cat. No.: HY-B1222AR
CAS No.: 32385-11-8
Synonyms: Antibiotic 6640 (Standard); Rickamicin (Standard)
Sisomicin (Standard) is the analytical standard of Sisomicin. This product is intended for research and analytical applications. Sisomicin is a broad-spectrum aminoglycoside antibiotic produced by Micromonospora inyoensis. Sisomicin is highly active against Gram-positive bacteria .
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