117 Results for "

p40

" in MedChemExpress (MCE) Product Catalog:
Products (117)

117 Results for "p40" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-P7032
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL-12; Interleukin 12; Interleukin-12 subunit alpha; IL-12A; Cytotoxic lymphocyte maturation factor 35 kDa subunit; CLMF p35; IL-12 subunit p35; Interleukin-12 subunit beta; IL-12B; Cytotoxic lymphocyte maturation factor 40 kDa subunit; CLMF p40; IL-12 subunit p40
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1 Cited Publications
Cat. No.: HY-128754
CAS No.: 111-03-5
Purity:  99.90%
Synonyms: MG (18:1)
Monoolein is a biocompatible lipid molecule that can be used as a carrier for bone repair. Monoolein exhibits anti-inflammatory activity by inhibiting the immune response induced by LPS (HY-D1056). It exerts its anti-inflammatory effects by reducing the production of immune response factors such as IL-12 p40, IL-6, and TNF-α, and inhibiting the generation of NO. Monoolein can be used in drug delivery and research in the field of inflammatory diseases .
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1 Cited Publications
Cat. No.: HY-P7046
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: rHuIL-9; Cytokine p40; T-cell Growth Factor p40
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CHO
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1 Cited Publications
Cat. No.: HY-P73195
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: IL-23 p19/IL-12 p40; IL23; IL-23A; Interleukin 23; SGRF
Species:  
Rat
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1 Cited Publications
Cat. No.: HY-P74816
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: IL-23 p19/IL-12 p40; IL23; IL-23A; Interleukin 23; SGRF
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1 Cited Publications
Cat. No.: HY-P70666
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL-12; Interleukin 12; Interleukin-12 subunit alpha; IL-12A; Cytotoxic lymphocyte maturation factor 35 kDa subunit; CLMF p35; IL-12 subunit p35; Interleukin-12 subunit beta; IL-12B; Cytotoxic lymphocyte maturation factor 40 kDa subunit; CLMF p40; IL-12 subunit p40;
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1 Cited Publications
Cat. No.: HY-N3307
CAS No.: 40957-99-1
(+)-Medioresinol is a furofuran-type lignan with antifungal and antibacterial properties. (+)-Medioresinol synergizes with antibiotics to exert antimicrobial and antibiofilm effects. (+)-Medioresinol induces intracellular ROS accumulation and mitochondrial-mediated apoptosis in Candida albicans. (+)-Medioresinol inhibits LPS (HY-D1056)-stimulated IL-12p40 production. (+)-Medioresinol is a PGC-1α activator that protects against endothelial cell pyroptosis in ischemic stroke via the PPARα-GOT1 axis. (+)-Medioresinol can be used in research on fungal and bacterial infection, inflammation, and ischemic stroke .
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1 Cited Publications
Cat. No.: HY-P75223
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Mitogen-activated protein kinase 1; MAPK 1; ERT1; ERK-2; p42-MAPK
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Cat. No.: HY-P99486
CAS No.: 339308-60-0
Synonyms: ABT-874

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Briakinumab (ABT-874) is a fully human anti-IL-12/23p40 monoclonal antibody. Briakinumab targets and neutralizes IL-12 and IL-23. Briakinumab can be used for the research of rheumatoid arthritis, inflammatory bowel disease, and multiple sclerosis .
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Cat. No.: HY-P990225
Anti-Mouse IL-12 p40 Antibody (C17.8) is a rat-derived anti-mouse IL-12 p40 IgG2a κ type antibody inhibitor. Anti-Mouse IL-12 p40 Antibody (C17.8) binds p40 subunit of IL-12. Anti-Mouse IL-12 p40 Antibody (C17.8) can be used for the researches of inflammation, immunology and metabolic disease, such as diabetes and arthritis .
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Cat. No.: HY-N2495
CAS No.: 52250-35-8
Isomucronulatol is a flavonoid isolated from the roots of A. membranaceus. Isomucronulatol exhibits inhibitory effects on LPS-stimulated production IL-12 p40 in vitro and has potential anti-inflammatory effect .
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Cat. No.: HY-N6250
CAS No.: 136087-29-1
Synonyms: Isomucronulatol 7-O-β-glucoside
Isomucronulatol 7-O-glucoside (Isomucronulatol 7-O-β-D-glucoside) is an isoflavonoid glycoside isolated from the roots of Astragalus membranaceus. Isomucronulatol 7-O-glucoside targets inflammation-related pathways in vitro to exert anti-inflammatory activity without cytotoxicity at effective concentrations. Isomucucronulatol 7-O-glucoside inhibits NO production and weakly suppresses IL‑12 p40 production in vitro. Isomucronulatol 7-O-glucoside can be used for the research on inflammation .
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Cat. No.: HY-N4061
CAS No.: 1383441-73-3
Hedycoronen A has inhibitory activity on the IL-6, IL-12 p40, and TNF-α production in LPS-Stimulated BMDCs, with IC50s of 9.1 μM, 5.6 μM, and 46.0 μM. Hedycoronen A can be isolated from Hedychium coronarium .
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Cat. No.: HY-171591
CAS No.: 2810810-00-3
SIK2-IN-4 (Compound 4) is a highly selective SIK1/2 inhibitor (IC50s 0.143 and 0.076 μM, respectively). SIK2-IN-4 reduces the phosphorylation of transcription coactivator 3 (CRTC3) by targeting SIK1/2, thereby regulating cAMP response element binding protein (CREB)-dependent transcriptional activity. SIK2-IN-4 inhibits the production of pro-inflammatory cytokines such as TNF (IC50: 0.11 µM), IL-12/23 p40 (IC50: 0.25 µM), and IL-23 (IC50: 0.47 µM), while inducing the expression of the anti-inflammatory cytokine IL-10. SIK2-IN-4 can be used to study intestinal inflammation and other chronic inflammatory diseases .
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Cat. No.: HY-123876
CAS No.: 2171502-44-4
Research Areas:  

Inflammation/Immunology

AS2677131 is a potent and orally active PIKfyve inhibitor. AS2677131 inhibits f IL-12p40, IL-6 and IL-1β through a PIKfyve-c-Rel pathway. AS2677131 selectively inhibits DNA-binding activity of c-Rel to IL-12p40 and IL-1β promoter. AS2677131 inhibits MHC class II expression on B cells. AS2677131 can be used for the researches of inflammation and immunology, such as arthritis .
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Cat. No.: HY-128754R
CAS No.: 111-03-5
Synonyms: MG (18:1) (Standard)
Monoolein is a biocompatible lipid molecule that can be used as a carrier for bone repair. Monoolein exhibits anti-inflammatory activity by inhibiting the immune response induced by LPS (HY-D1056). It exerts its anti-inflammatory effects by reducing the production of immune response factors such as IL-12 p40, IL-6, and TNF-α, and inhibiting the generation of NO. Monoolein can be used in drug delivery and research in the field of inflammatory diseases .
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Cat. No.: HY-177091
CAS No.: 2171506-45-7
Research Areas:  

Inflammation/Immunology

AS2795440 is a PIKfyve inhibitor. AS2795440 selectively inhibits proinflammatory cytokine such as IL-12p40 and IL-6 production and B cell activation without affecting Ca 2+ signaling. AS2795440 significantly reduces joint inflammation and bone loss in adjuvant-induced arthritis (AIA) mice model. AS2795440 can be used for inflammatory and autoimmune diseases like rheumatoid arthritis, psoriasis and inflammatory bowel disease research .
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Cat. No.: HY-P78319
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: Interleukin-9; IL-9; Cytokine p40; T-cell growth factor p40; Hp40; p40
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Cat. No.: HY-P701014
Purity:  ≥ 95%, as determined by Bis-Tris PAGE. ≥ 95% as determined by HPLC.
Synonyms: Interleukin-9; IL-9; Cytokine p40; T-cell growth factor p40; Hp40; p40
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Cat. No.: HY-P7083
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: rMuIL-9; Cytokine p40; T-cell Growth Factor p40
Species:  
Source:  
CHO
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