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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
117 Results for "
proteinase inhibitor
" in MedChemExpress (MCE) Product Catalog:
Products (117)
117 Results for "proteinase inhibitor" in MCE Product Catalog:
25
25 Publications Verification
Synonyms: proteinase inhibitor E 64
Research Areas:
E-64 (Proteinase inhibitor E 64) is a potent irreversible inhibitor against general cysteine proteases with IC50 of 9 nM for papain.
4
Target:
Research Areas:
Gabexate mesylate (FOY) is is a competitive and non-antigenic synthetic inhibitor of trypsin-like serine proteinases. Gabexate mesylate inhibits human thrombin, urokinase, plasmin, and Factor Xa with Kis of 0.97, 1.3, 1.6, and 8.5 μM, respectively. Gabexate mesylate binds to human and bovine tryptase with Kis of 3.4 nM and 18 μM, respectively. Gabexate mesylate exerts an anticoagulant effect on the clotting activity of thrombin and has anti-inflammatory effect by viainhibition of NF-κB, proinflammatory cytokines, and nitric oxide. Gabexate mesylate is used for pancreatitis and disseminated intravascular coagulation .
3
3 Cited Publications
Target:
Research Areas:
2
2 Cited Publications
Research Areas:
Z-LVG-CHN2 is a cell-permeable and irreversible inhibitor of cysteine proteinase. Z-LVG-CHN2 is a tripeptide derivative and mimics part of the human cysteine proteinase-binding center. Z-LVG-CHN2 displays an inhibition on HSV whereas no significant effect on poliovirus replication. Z-LVG-CHN2 effectively blocks SARS-COV-2 replication (EC50=190 nM) via inhibition of SARS-COV-2 3CL pro protease .
2
2 Cited Publications
Cat. No.: HY-19727A
CAS No.: 71079-09-9
Target:
Research Areas:
FOY 251, an anti-proteolytic active metabolite Camostate (HY-13512), acts as a proteinase inhibitor . FOY 251 inhibits SARS-CoV-2 infection in cells assay .
2
2 Cited Publications
Cat. No.: HY-P73414
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: SLPI; Secretory Leukocyte Protease inhibitor (Antileukoproteinase); Secretory Leukocyte Peptidase inhibitor; WAP Four-Disulfide Core Domain Protein 4; WFDC4; Seminal proteinase inhibitor; BLPI; Mucus proteinase inhibitor; WAP4; Protease inhibitor WAP4; AL
Species:
Human
Source:
Sf9 insect cells
2
2 Cited Publications
Cat. No.: HY-P71077
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SERPINE1; Endothelial Plasminogen Activator inhibitor; Prev. PLANH1; Serpin E1; Prev. PAI1; PAI-1; PAI; Serpin Peptidase inhibitor, Clade E (Nexin, Plasminogen Activator inhibitor Type 1), Member 1; Serine (Or Cysteine) proteinase inhibitor, Clade E (Nexi
Species:
Human
Source:
HEK293
2
2 Cited Publications
Cat. No.: HY-P7419
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SERPINA12; Serine (Or Cysteine) proteinase inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 12; Serpin Family A Member 12; Serpin Peptidase inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 12; Vaspin; Serpin A12; OL-64; Vis
Species:
Human
Source:
E. coli
1
1
1 Cited Publications
Cat. No.: HY-103351
CAS No.: 429676-93-7
Target:
Research Areas:
Cathepsin G Inhibitor I (Compound 7) is a potent, selective, reversible, competitive, non-peptidic Cathepsin G inhibitor (IC50 = 53 nM; Ki = 63 nM). Cathepsin G Inhibitor I can be used in research related to immune disorders .
1
Target:
Research Areas:
Cinanserin hydrochloride (SQ 10643) is a potent, selective and highly affinity 5-HT2 receptor antagonist with a Ki of 41 nM. Cinanserin hydrochloride has a much higher binding affinity for the 5-HT2 than for the 5-HT1 receptor (Ki of 3500 nM). Cinanserin is also an inhibitor of 3C-like proteinase of severe acute respiratory syndrome coronavirus and strongly reduces virus replication in vitro .
1
1 Cited Publications
Cat. No.: HY-P73526
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SERPING1; Serine (Or Cysteine) proteinase inhibitor, Clade G (C1 inhibitor), Member 1, (Angioedema, Hereditary); Prev. C1NH; Serine/Cysteine proteinase inhibitor Clade G Member 1 Splice Variant 2; Plasma Protease C1 inhibitor; Serine/Cysteine proteinase I
Species:
Human
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-P71133
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SERPINE1; Endothelial Plasminogen Activator inhibitor; Prev. PLANH1; Serpin E1; Prev. PAI1; PAI-1; PAI; Serpin Peptidase inhibitor, Clade E (Nexin, Plasminogen Activator inhibitor Type 1), Member 1; Serine (Or Cysteine) proteinase inhibitor, Clade E (Nexin, Plasminogen Activator inhibitor Type 1), Member 1; Plasminogen Activator inhibitor, Type I; Serpin Family E Member 1; Plasminogen Activator inhibitor 1
Species:
Mouse
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-P72831
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: SERPINC1; Signal Peptide Antithrombin Part 1; Prev. AT3; Antithrombin III; ATIII; SERPINC1 Protein; Antithrombin-III; Antithrombin; Serine (Or Cysteine) proteinase inhibitor, Clade C (Antithrombin), Member 1; ATIII-R2; Serpin Peptidase inhibitor, Clade C
Species:
Human
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-P71143
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SERPINA4; Testicular Secretory Protein Li 22; Prev. PI4; Peptidase inhibitor 4; KST; Kallikrein inhibitor; Kallistatin; Serpin A4; KLST; PI-4; KAL; Serpin Peptidase inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 4, Isoform CRA_a; Serine (Or Cysteine) proteinase inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 4; Protease inhibitor 4 (Kallistatin); Serpin Peptidase inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 4; Serpin Family A Member 4; Sserpin Family A Member 4
Species:
Human
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-P72965
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CSTB; Cystatin B (Stefin B); Prev. STFB; CPI-B; Prev. EPM1; Epididymis Secretory Sperm Binding Protein; CST6; Epilepsy, Progressive Myoclonic 1; Cystatin-B; Stefin B; PME; EPM1A; Liver Thiol proteinase inhibitor; ULD; Cystatin B; Stefin-B
Species:
Human
Source:
E. coli
Synonyms: ONO-6818; ONO-PO-736
Target:
Research Areas:
Freselestat (ONO-6818) is a potent and orally active neutrophil elastase inhibitor with a Ki of 12.2 nM. Freselestat is >100-fold less-active against other proteases such as trypsin, protein-ase 3, pancreatic elastase, plasmin, thrombin, collagenase, cathepsin G, and murine macrophage elastase. Freselestat has a potent anti-inflammatory activity .
Synonyms: Elastase inhibitor III
Target:
Research Areas:
Target:
Research Areas:
1,8-Dihydroxy-4,5-dinitroanthraquinone (ARDP0006; DHDNE) is a potent inhibitor of serine proteinase NS2B/3, the dengue viral protein. 1,8-Dihydroxy-4,5-dinitroanthraquinone has intermolecular proteinase activity and viral inhibition ability with IC50s of 432 μM and 4.2 μM, respectively. Meanwhile 1,8-Dihydroxy-4,5-dinitroanthraquinone inhibits NS2B/3 cleavage in BHK-21 cells at a dose ranging from 4.2 μM to 432 μM .
Target:
Research Areas:
Neutrophil elastase inhibitor 5 is an inhibitor of human neutrophil elastase (HNE), proteinase 3 (PR3) and sirt2, with IC50 values of 4.91, 20.69 and 2.42 μM, respectively. Neutrophil elastase inhibitor 5 inhibits superoxide anion production and elastase release in human neutrophils. Neutrophil elastase inhibitor 5 can be used for the research of neutrophil inflammatory diseases .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
