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respiratory syncytial virus B

" in MedChemExpress (MCE) Product Catalog:

By Targets:	RSV (14) 5-HT Receptor (1) Apoptosis (1) Bacterial (1) Calcium Channel (1) HBV (2) HCV (1) Isotope-Labeled Compounds (1) MDM-2/p53 (1) Reference Standards (1) Sirtuin (1) Toll-like Receptor (TLR) (1)
By Research Areas:	Infection (19) Inflammation/Immunology (1)
Oligonucleotides:	CpG ODNs (1)

Inhibitors & Agonists

Inhibitory Antibodies

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Recombinant Proteins

Isotope-Labeled Compounds

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Targets Recommended: RSV

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N6771

Cyclopiazonic acid 5+ Cited Publications	Calcium Channel 5-HT Receptor MDM-2/p53 Apoptosis RSV	Infection
Cyclopiazonic acid is an endoplasmic reticulum calcium ATPase (ECAs) inhibitor and human respiratory syncytial virus (RSV) inhibitor (EC₅₀ value of 4.13 μ M), which can reduce the antagonistic effect of 5-HT receptors in rat thoracic aorta, induce p53 dependent cell apoptosis and reproductive toxicity in mouse testes, and inhibit the biological activation of aflatoxin B ^[1][4][5].

HY-P99756

Nirsevimab 2 Publications Verification MEDI8897	RSV	Infection
Nirsevimab (MEDI8897) is a recombinant monoclonal antibody against human respiratory syncytial virus (RSV). Nirsevimab has neutralizing activity against RSV A and RSV B viruses, with IC₅₀ values of 5.42 ng/mL and 9.71 ng/mL, respectively. Nirsevimab can be used for research on respiratory infections .

HY-109035

Inarigivir soproxil 1 Publications Verification SB9200; GS-9992	HCV HBV	Infection
Inarigivir soproxil (SB9200) is an agonist of innate immunity and shows potent antiviral activity against resistant HCV variants, with EC₅₀s of 2.2 and 1.0 μM for HCV 1a/1b in cells of genotype 1 HCV replicon systems. Inarigivir soproxil, an orally bioavailable proagent of SB 9000, has broad-spectrum antiviral activity against RNA viruses including HCV, norovirus, respiratory syncytial virus and influenza and HBV .

HY-P99804

Clesrovimab 3 Publications Verification MK1654	RSV	Infection
Clesrovimab (MK1654) is a humanized IgG1 monoclonal antibody targeting the respiratory syncytial virus (RSV) protein F. Clesrovimab binds to pre-fusion and post-fusion forms of RSV-A fusion protein with high affinity, with corresponding K_D values of 71 pM and 480 pM, respectively. Clesrovimab is applicable for the research of RSV infection .

HY-150217

CpG ODN 10101 2 Publications Verification ODN 10101	Toll-like Receptor (TLR)	Infection Inflammation/Immunology
CpG ODN 10101 (ODN 10101; CPG 10101) is a selective agonist targeting TLR9, a synthetic oligodeoxynucleotide modified with phosphate thioester. CpG ODN 10101 activates B cells and plasmacytoid dendritic cells (pDCs), inducing the production of cytokines and chemokines such as interferon-IFN-α, interferon-inducible protein IP-10, and 2'5'-oligoadenylate synthase (2'5'-OAS), regulating innate immunity and promoting Th1 adaptive immune responses. CpG ODN 10101 also possesses antiviral properties and enhances vaccine immunogenicity, making it suitable as an immunomodulator and vaccine adjuvant for vaccine development in chronic hepatitis C and infectious diseases such as melioidosis, pertussis, and respiratory syncytial virus (RSV) .

HY-123475A

Sisunatovir hydrochloride 4 Publications Verification RV521 hydrochloride	RSV	Infection
Sisunatovir (RV521) hydrochloride is a potent and orally active respiratory syncytial virus (RSV) inhibitor with IC₅₀ values of 1.4, 1.0 nM for RSV A, RSV B, respectively. Sisunatovir hydrochloride inhibits RSV infection and reduces virus titers in the lungs of mice .

HY-123475

Sisunatovir 4 Publications Verification RV521	RSV	Infection
Sisunatovir (RV521) is a potent and orally active respiratory syncytial virus (RSV) inhibitor with IC₅₀ values of 1.4, 1.0 nM for RSV A, RSV B, respectively. Sisunatovir inhibits RSV infection and reduces virus titers in the lungs of mice .

HY-102038

PC786 2 Publications Verification	RSV	Infection
PC786 is an inhaled respiratory syncytial virus (RSV) L protein polymerase inhibitor. PC786 demonstrates potent antiviral activity against RSV-A (IC₅₀ <0.09 to 0.71 nM) and *RSV-B* (IC₅₀, 1.3 to 50.6 nM) .

HY-12993

RSV604 2 Publications Verification A-60444	RSV	Infection
RSV604 (A-60444) is an inhibitor of respiratory syncytial virus (RSV) replication. RSV604 targets the nucleocapsid protein, with a K_d of 1.6 μM. RSV604 displays submicromolar activity against numerous clinical isolates of both the A and B subtypes of RSV (average EC₅₀s=0.8 μM) .

HY-120632

BMS-433771	RSV	Infection
BMS-433771 is a potent orally active inhibitor of respiratory syncytial virus (RSV). BMS-433771 is active against both A and B groups of RSV, with an average EC₅₀ of 20 nM. BMS-433771 can be used for the research of respiratory tract disease .

HY-111296

YM 53403	RSV	Infection
YM 53403 is an anti-respiratory syncytial virus (RSV) agent, with an EC₅₀ of 0.20 μM. YM 53403 potently inhibits the replication of RSV strains belonging to both A and B subgroups .

HY-126033

Sophoranol	HBV RSV	Infection
Sophoranol is an alkaloid that can be isolated from S. flavescens, with antiviral activity. Sophoranol has anti-HBV (hepatitis B virus) activity. Sophoranol shows potent antiviral activities against respiratory syncytial virus (RSV) with an IC₅₀ of 10.4 μg/mL .

HY-11098

JNJ 2408068 R170591	RSV	Infection
JNJ 2408068 is a potent RSV (respiratory syncytial virus) inhibitor. JNJ 2408068 significantly inhibits replication of RSV A and B subtypes in the lungs of cotton rats without any evidence of toxicity. The minimum protective dose of JNJ 2408068 appears to be approximately 0.39 mg/kg .

HY-163532

FLS-359	Sirtuin	Infection
FLS-359 is a selective, orally active allosteric modulator for sirtuin 2, with the IC₅₀ of 3 μM. FLS-359 exhibits antiviral activity against RNA and DNA virus, through inhibition of DNA/RNA replication .

HY-119375

Syncytial Virus Inhibitor-1	Bacterial	Infection
Syncytial Virus Inhibitor-1 is a potent, orally bioavailable respiratory syncytial virus (RSV) fusion inhibitor with EC₅₀s of 0.002 μM, 0.004 μM, and 0.002 μM for RSV Long, RSV A2, and RSV B strains, respectively .

HY-120632A

BMS-433771 dihydrochloride hydrate	RSV	Infection
BMS-433771 dihydrochloride hydrate is a potent orally active inhibitor of respiratory syncytial virus (RSV). BMS-433771 dihydrochloride hydrate is active against both A and B groups of RSV, with an average EC₅₀ of 20 nM. BMS-433771 dihydrochloride hydrate can be used for the research of respiratory tract disease .

HY-P992423

NIAID RSVF2-5	RSV	Infection
NIAID RSVF2-5 is a human monoclonal antibody fragment. NIAID RSVF2-5 binds to conserved, distinct conformational epitopes on RSV fusion glycoprotein, and shows activity against RSV subgroup A and B strains. NIAID RSVF2-5 reduces pulmonary and lung viral titers in RSV-infected rodents. NIAID RSVF2-5 can be used for the research of respiratory syncytial virus infection .

HY-102038R

PC786 (Standard)	Reference Standards RSV	Infection
PC786 (Standard) is the analytical standard of PC786 (HY-102038). This product is intended for research and analytical applications. PC786 is an inhaled respiratory syncytial virus (RSV) L protein polymerase inhibitor. PC786 demonstrates potent antiviral activity against RSV-A (IC₅₀ <0.09 to 0.71 nM) and RSV-B (IC₅₀, 1.3 to 50.6 nM) .

HY-N6771S

Cyclopiazonic acid-13C20	Isotope-Labeled Compounds	Infection
Cyclopiazonic acid- ¹³C₂₀ is the ¹³C-labeled Cyclopiazonic acid (HY-N6771). Cyclopiazonic acid is an endoplasmic reticulum calcium ATPase (ECAs) inhibitor and human respiratory syncytial virus (RSV) inhibitor (EC₅₀ value of 4.13 μ M), which can reduce the antagonistic effect of 5-HT receptors in rat thoracic aorta, induce p53 dependent cell apoptosis and reproductive toxicity in mouse testes, and inhibit the biological activation of aflatoxin B .

Cat. No.	Product Name	Target	Research Area	Image

HY-P99756

Nirsevimab 2 Publications Verification MEDI8897	RSV	Infection
Nirsevimab (MEDI8897) is a recombinant monoclonal antibody against human respiratory syncytial virus (RSV). Nirsevimab has neutralizing activity against RSV A and RSV B viruses, with IC₅₀ values of 5.42 ng/mL and 9.71 ng/mL, respectively. Nirsevimab can be used for research on respiratory infections .

HY-P99804

Clesrovimab 3 Publications Verification MK1654	RSV	Infection
Clesrovimab (MK1654) is a humanized IgG1 monoclonal antibody targeting the respiratory syncytial virus (RSV) protein F. Clesrovimab binds to pre-fusion and post-fusion forms of RSV-A fusion protein with high affinity, with corresponding K_D values of 71 pM and 480 pM, respectively. Clesrovimab is applicable for the research of RSV infection .

HY-P992423

NIAID RSVF2-5	RSV	Infection
NIAID RSVF2-5 is a human monoclonal antibody fragment. NIAID RSVF2-5 binds to conserved, distinct conformational epitopes on RSV fusion glycoprotein, and shows activity against RSV subgroup A and B strains. NIAID RSVF2-5 reduces pulmonary and lung viral titers in RSV-infected rodents. NIAID RSVF2-5 can be used for the research of respiratory syncytial virus infection .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N6771

Cyclopiazonic acid 5+ Cited Publications	Alkaloids Structural Classification Microorganisms Pyrrole Alkaloids Classification of Application Fields Other Diseases Disease Research Fields Indole Alkaloids Source Classification	Calcium Channel 5-HT Receptor MDM-2/p53 Apoptosis RSV
Cyclopiazonic acid is an endoplasmic reticulum calcium ATPase (ECAs) inhibitor and human respiratory syncytial virus (RSV) inhibitor (EC₅₀ value of 4.13 μ M), which can reduce the antagonistic effect of 5-HT receptors in rat thoracic aorta, induce p53 dependent cell apoptosis and reproductive toxicity in mouse testes, and inhibit the biological activation of aflatoxin B ^[1][4][5].

HY-126033

Sophoranol	Infection Alkaloids Piperidine Alkaloids Classification of Application Fields Leguminosae Plants Sophora flavescens Aiton Disease Research Fields Source Classification	HBV RSV
Sophoranol is an alkaloid that can be isolated from S. flavescens, with antiviral activity. Sophoranol has anti-HBV (hepatitis B virus) activity. Sophoranol shows potent antiviral activities against respiratory syncytial virus (RSV) with an IC₅₀ of 10.4 μg/mL .

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P71478

	Fusion glycoprotein F0/F Protein, HRSV (His, B2M) Fusion glycoprotein F0; Protein F; Interchain peptide; Fusion glycoprotein F2; Human respiratory syncytial virus A Fusion glycoprotein F0	Virus	E. coli
	The fusion glycoprotein F0/F protein is initially an inactive precursor that is cleaved by furin-like proteases to produce the mature F1 and F2 fusion glycoproteins. As a class I viral fusion protein, it undergoes prefusion, prehairpin, and postfusion states. Fusion glycoprotein F0/F Protein, HRSV (His, B2M) is the recombinant Virus-derived Fusion glycoprotein F0/F protein, expressed by E. coli , with N-B2M, N-6*His labeled tag.

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HY-N6771S

Cyclopiazonic acid-13C20
Cyclopiazonic acid- ¹³C₂₀ is the ¹³C-labeled Cyclopiazonic acid (HY-N6771). Cyclopiazonic acid is an endoplasmic reticulum calcium ATPase (ECAs) inhibitor and human respiratory syncytial virus (RSV) inhibitor (EC₅₀ value of 4.13 μ M), which can reduce the antagonistic effect of 5-HT receptors in rat thoracic aorta, induce p53 dependent cell apoptosis and reproductive toxicity in mouse testes, and inhibit the biological activation of aflatoxin B .

Cyclopiazonic acid-13C20

Cyclopiazonic acid- ¹³C₂₀ is the ¹³C-labeled Cyclopiazonic acid (HY-N6771). Cyclopiazonic acid is an endoplasmic reticulum calcium ATPase (ECAs) inhibitor and human respiratory syncytial virus (RSV) inhibitor (EC₅₀ value of 4.13 μ M), which can reduce the antagonistic effect of 5-HT receptors in rat thoracic aorta, induce p53 dependent cell apoptosis and reproductive toxicity in mouse testes, and inhibit the biological activation of aflatoxin B .

Cat. No.	Product Name		Classification