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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
65 Results for "
ribosomal s6 kinase
" in MedChemExpress (MCE) Product Catalog:
Products (65)
65 Results for "ribosomal s6 kinase" in MCE Product Catalog:
17
8
Category:
Flavonols Flavonoids Pityrogramma triangularis Plants Other Families Extract Disease Research Fields Cancer
Target:
8
8 Cited Publications
Cat. No.: HY-16104
CAS No.: 1311367-27-7
Target:
Research Areas:
BIX 02565 is a potent ribosomal S6 kinase 2 (RSK2) inhibitor with IC50 of 1.1 nM.
5
5 Cited Publications
Cat. No.: HY-19713
CAS No.: 1627709-94-7
Target:
Research Areas:
LJI308 is a potent pan-ribosomal S6 kinase (RSK) inhibitor, with IC50s of 6 nM, 4 nM, and 13 nM for RSK1, RSK2, and RSK3, respectively. LJI308 inhibits the phosphorylation of RSK (T359/S363) and YB-1 (S102) after irradiation, treatment with EGF, and in cells expressing a KRAS mutation .
1
1 Cited Publications
Cat. No.: HY-W011109
CAS No.: 1177141-67-1
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Research Areas:
CKI-7 is a potent and ATP-competitive casein kinase 1 (CK1) inhibitor with an IC50 of 6 μM and a Ki of 8.5 μM. CKI-7 is a selective Cdc7 kinase inhibitor. CKI-7 also inhibits SGK, ribosomal S6 kinase-1 (S6K1) and mitogen- and stress-activated protein kinase-1 (MSK1). CKI-7 has a much weaker effect on casein kinase II and other protein kinases .
1
1 Cited Publications
Cat. No.: HY-133028
CAS No.: 120615-25-0
Target:
Research Areas:
CKI-7 free base is a potent and ATP-competitive casein kinase 1 (CK1) inhibitor with an IC50 of 6 μM and a Ki of 8.5 μM. CKI-7 free base is a selective Cdc7 kinase inhibitor. CKI-7 free base also inhibits SGK, ribosomal S6 kinase-1 (S6K1) and mitogen- and stress-activated protein kinase-1 (MSK1). CKI-7 free base has a much weaker effect on casein kinase II and other protein kinases .
Cat. No.: HY-175256
CAS No.: 799832-19-2
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RSK2-IN-5 (compoud C24) is a p90 ribosomal S6 kinase 2 (RSK2) inhibitor with a Kd of 317 nM. RSK2-IN-5 exhibits antitumor activity against breast cancer and melanoma cancer cells .
Cat. No.: HY-52101C
CAS No.: 1414811-15-6
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FMK-MEA is a potent and selective p90 Ribosomal S6 Kinase (RSK) inhibitor.
Cat. No.: HY-156872
CAS No.: 1952236-19-9
MTX-216 is a dual ATP-competitive inhibitor of PI3K and EGFR. MTX-216 cosuppresses Ki-67 and ribosomal S6 phosphorylation and induces apoptosis in NF1 LOF cells. MTX-216 suppresses the activity of SYK kinase, with an IC50 of 281 nM. MTX-216 is used in the research of Melanoma .
Cat. No.: HY-P3814
Target:
Research Areas:
Cat. No.: HY-P5449
CAS No.: 171783-08-7
Target:
Research Areas:
Cat. No.: HY-177347
CAS No.: 304474-86-0
Target:
Research Areas:
RSK2-IN-5 (compoud C2) is a p90 ribosomal S6 kinase 2 (RSK2) inhibitor with a Kd of 856 nM. RSK2-IN-5 exhibits antitumor activity against breast cancer and melanoma cancer cells .
Cat. No.: HY-178029
Research Areas:
RSK2/TOP2-IN-1 is a RSK2/TOP2 dual inhibitor. RSK2/TOP2-IN-1 targets key tumor progression enzymes including ribosomal S6 kinase 2 and topoisomerases IIα/IIβ. RSK2/TOP2-IN-1 shows selectivity index > 2 against all squamous cell carcinoma (SCC) cell lines. RSK2/TOP2-IN-1 can induce cell apoptosis, autophagy and ROS production. RSK2/TOP2-IN-1 can be used for the research of cancer, such as squamous cell carcinoma .
Cat. No.: HY-P87710
Synonyms: STK14A, ribosomal protein s6 kinase beta-1, s6K-beta-1, s6K1, 70 kDa ribosomal protein s6 kinase 1, ribosomal protein s6 kinase I, Serine/threonine-protein kinase 14A, p70 ribosomal s6 kinase alpha, P70s6K1, p70-s6K 1, p70 s6 kinase alpha, p70 s6K-alpha, p70 s6KA
Cat. No.: HY-P86528
Synonyms: RPs6KB1; STK14A; ribosomal protein s6 kinase beta-1; s6K-beta-1; s6K1; 70 kDa ribosomal protein s6 kinase 1; P70s6K1; p70-s6K 1; ribosomal protein s6 kinase I; Serine/threonine-protein kinase 14A; p70 ribosomal s6 kinase alpha; p70 s6 kinas
Cat. No.: HY-P702651
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: RPs6KA6; RSK-4; ribosomal Protein s6 kinase A6; ribosomal Protein s6 kinase, 90kDa, Polypeptide 6; RSK4; ribosomal Protein s6 kinase, 90kD, Polypeptide 6; 90 KDa ribosomal Protein s6 kinase 6; Non-Specific Serine/Threonine Protein kinase; ribosomal Protei
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P705570
Synonyms: RPs6KB1; ribosomal Protein s6 kinase, 70kDa, Polypeptide 1; Prev. STK14A; 70 KDa ribosomal Protein s6 kinase 1; s6K1; Serine/Threonine kinase 14 Alpha; P70(s6K)-Alpha; P70 ribosomal s6 kinase Alpha; Ps6K; P70 s6 kinase Alpha; s6K; RPs6KB1 Protein; Serine/Threonine-Protein kinase 14A; P70 s6K-Alpha; ribosomal Protein s6 kinase Beta-1; P70-Alpha; ribosomal Protein s6 kinase I; P70-s6K 1; s6K-Beta-1; P70-s6K; P70 s6KA; P70s6K1; ribosomal Protein s6 kinase B1; ribosomal Protein s6 kinase, 70kD, Polypeptide 1
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P76011
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: RPs6KA2; ribosomal Protein s6 kinase, 90kDa, Polypeptide 2; ribosomal Protein s6 kinase A2; ribosomal Protein s6 kinase, 90kD, Polypeptide 2; RSK3; Non-Specific Serine/Threonine Protein kinase; HU-2; 90 KDa ribosomal Protein s6 kinase 2; MAP kinase-Activa
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P81769
Synonyms: RPs6KB2; STK14B; ribosomal protein s6 kinase beta-2; s6K-beta-2; s6K2; 70 kDa ribosomal protein s6 kinase 2; P70s6K2; p70-s6K 2; s6 kinase-related kinase; SRK; Serine/threonine-protein kinase 14B; p70 ribosomal s6 kinase beta; s6K-beta; p70
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
