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Results for "

solubilizing

" in MedChemExpress (MCE) Product Catalog:

By Targets:	ADC Linker (2) Adenosine Receptor (2) Adrenergic Receptor (1) Amylases (2) Amyloid-β (1) Apoptosis (3) Bacterial (1) Biochemical Assay Reagents (76) Drug Derivative (1) Endogenous Metabolite (4) Environmental Pollutants (23) Exosomes (2) Fungal (1) GCGR (1) GLUT (2) Influenza Virus (2) Isotope-Labeled Compounds (5) Itk (1) Liposome (2) NF-κB (2) Reference Standards (3) Stearoyl-CoA Desaturase (SCD) (1)
By Research Areas:	Cancer (7) Cardiovascular Disease (1) Infection (5) Inflammation/Immunology (3) Metabolic Disease (7) Neurological Disease (3)
Click Chemistry:	Azide (2) Alkynes (1)
Oligonucleotides:	Thickeners (1) Suspending Agents (1) Emulsifiers (5) Solubilizing Agents (5) Surfactants (5)

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Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-101461

Methyl-β-cyclodextrin Maximum Cited Publications 106 Publications Verification Methyl-beta-cyclodextrin	Environmental Pollutants Biochemical Assay Reagents	Cancer
Methyl-β-cyclodextrin (Methyl-beta-cyclodextrin) is a cyclic heptasaccharide used to deliver hydrophobic agents based on its property of solubilizing non-polar substances. Methyl-β-cyclodextrin is also extensively used as a cholesterol-depleting reagent . Methyl-β-cyclodextrin strongly reduces clathrin-dependent endocytosis . Methyl-β-cyclodextrin blocks cell migrasome formation .

HY-15435

CHAPS 4 Publications Verification	Exosomes Biochemical Assay Reagents	Others
CHAPS is a cholic acid-derived, sulfobetaine-type zwitterionic detergent and micelle-forming agent. CHAPS exhibits properties of weak cationic or nonionic surfactants in different solution systems, undergoes micellization, and forms small, loose hydrophilic aggregates that are temperature-dependent. CHAPS stabilizes mononucleosomes under different ionic strengths, reduces nucleosome sequence specificity, promotes sliding of histone cores along DNA, solubilizes Tamm-Horsfall protein to reduce its interference with urinary exosome isolation, and maintains vesicle structure and the activity of related proteins at the same time. CHAPS is used to recover native folded fusion proteins, enhance the binding capacity of GST fusion proteins, and restore GST enzyme activity. However, CHAPS cannot refold proteins denatured by urea, guanidine hydrochloride or heat, nor can it construct the structure of intrinsically disordered proteins. CHAPS is commonly used in research on the separation and purification of membrane proteins .

HY-116285

n-Octyl β-D-glucopyranoside 3 Publications Verification	Biochemical Assay Reagents	Others
n-Octyl-β-d-glucopyranoside is a non-ionic detergent, it can be widely used in the research of biotechnical, biochemical applications, solubilization and crystallization of membrane proteins. n-Octyl-β-d-glucopyranoside can completely inhibit cavitation-induced cell lysis in vitro .

HY-Y0873Q

PEG20000 Polyethylene glycol 20000	Environmental Pollutants Biochemical Assay Reagents	Others
PEG20000 (Polyethylene glycol 20000) can be used as a solubilizer. PEG20000 is a kind of biological materials or organic compounds that are widely used in life science research, can be degraded by bacteria .

HY-B1620L

Polyvinylpyrrolidone, average Mw~40000 PVP, average Mw~40000; Polyvidone, average Mw~40000; Povidone, average Mw~40000	Environmental Pollutants Biochemical Assay Reagents	Others
Polyvinylpyrrolidone, average Mw~40000 is a multifunctional synthetic polymer with an average molecular weight of 40,000 Da. Polyvinylpyrrolidone, average Mw~40000 is widely used to synthesize nanoparticles. Polyvinylpyrrolidone, average Mw~40000 is a versatile excipient for both conventional formulations and novel controlled or targeted delivery systems, serving as a binder, coating agent, suspending agent, pore-former, solubilizer, stabilizer, etc .

HY-126403

Ethoxylated hydrogenated castor oil 2 Publications Verification PEG-40 hydrogenated castor oil; Macrogolglycerol hydroxystearate; Castor oil, hydrogenated, polyethoxylated	Environmental Pollutants Biochemical Assay Reagents	Others
Ethoxylated hydrogenated castor oil (PEG-40 hydrogenated castor oil) is a combination of synthetic polyethylene glycol (PEG) with natural castor oil. Ethoxylated hydrogenated castor oil can be used to emulsify and solubilize oil-in-water (o/w) emulsions. Ethoxylated hydrogenated castor oil can be used as a cosolvent in vivo .

HY-Y1883

Polyethylene glycol mono(4-tert-octylphenyl) ether surfactant 20+ Cited Publications	Environmental Pollutants Biochemical Assay Reagents Apoptosis	Infection Cancer
Polyethylene glycol mono(4-tert-octylphenyl) ether surfactant is a non-denaturing detergent that solubilizes lipid membranes. Polyethylene glycol mono(4-tert-octylphenyl) ether surfactant is commonly used in laboratories and is applied to vaccines at different stages of the manufacturing process. Polyethylene glycol mono(4-tert-octylphenyl) ether surfactant is listed as an excipient in certain vaccines including split virus influenza vaccines. Polyethylene glycol mono(4-tert-octylphenyl) ether surfactant is a nonionic surfactant. Polyethylene glycol mono(4-tert-octylphenyl) ether surfactant induces Apoptosis in prostate and colon cancer cell lines and reduces the infectivity of classic enveloped viruses such as WNV .

HY-138941

Octaethylene glycol monododecyl ether 1 Publications Verification C12E8	Influenza Virus	Infection
Octaethylene glycol monododecyl ether (C12E8) is an non-ionic detergent that can be used for membrane protein extraction. Octaethylene glycol monododecyl ether can solubilize the viral membrane of intact influenza virus .

HY-E70013

Lichenase, Microorganism endo-1,3:1,4-β-D-Glucanase	Endogenous Metabolite	Metabolic Disease
Lichenase, Microorganism (endo-1,3:1,4-β-D-Glucanase) is a specific, endo-(1-3),(1-4)-β-D-glucan 4-glucanohydrolase. Lichenase, Microorganism solubilizes β-glucans from cereal grains and gives gluco-oligosaccharides (GOS). Lichenase, Microorganism can be used in the degradation of polysaccharides in the cell walls .

HY-137234

DM-β-CD 2,6-Di-O-methyl-β-cyclodextrin	Biochemical Assay Reagents	Others
DM-β-CD (2,6-Di-O-methyl-β-cyclodextrin) is a cyclic molecule consisting of seven glucose units modified with two methyl groups at the 2- and 6-positions. It is usually used as a solubilizer and carrier for poorly soluble drugs in pharmaceutical preparations. Furthermore, it has applications in analytical chemistry, food science, and environmental remediation due to its ability to form clathrates with various guest molecules, such as aromatic compounds, pesticides, and heavy metals.

HY-401424

Cremophor EL-36 Polyoxyethylene(36) Castor Oil; PEG-36 Castor Oil	Environmental Pollutants Biochemical Assay Reagents	Others
Cremophor EL-36 is a non-ionic surfactant, mainly used as a solubilizing carrier for poorly soluble Paclitaxel (HY-B0015). For example, Cremophor EL-36 can enhance the intracellular influx of Etoposide (HY-13629) without affecting drug efflux, and can dose-dependently increase the accumulation of VP-16 in lung adenocarcinoma cells (such as PC-14 and A549), significantly enhancing its cytotoxic effect .

HY-W134422

(1,1,3,3-Tetramethylbutyl)phenyl-polyethylene glycol X-114 2 Publications Verification Polyoxyethylene octylphenol ether	Environmental Pollutants Biochemical Assay Reagents	Others
(1,1,3,3-Tetramethylbutyl)phenyl-polyethylene glycol X-114 is a surfactant. (1,1,3,3-Tetramethylbutyl)phenyl-polyethylene glycol X-114 is used to solubilize membranes and whole cells. A solution of (1,1,3,3-Tetramethylbutyl)phenyl-polyethylene glycol X-114 is homogeneous at 0 degrees C but separates in an aqueous phase and a detergent phase above 20 degrees C. (1,1,3,3-Tetramethylbutyl)phenyl-polyethylene glycol X-114 can be used in phase separation studies .

HY-B1620E

Polyvinylpyrrolidone K60 PVP K60; Polyvidone K60; Povidone K60	Biochemical Assay Reagents	Others
Polyvinylpyrrolidone K60 is one of the polymers in pharmaceutical preparations. Polyvinylpyrrolidone K60 promotes amorphous dispersion and inhibits crystallization of the drug .

HY-N0668

Rubusoside 2 Publications Verification	GLUT Amylases NF-κB	Metabolic Disease Inflammation/Immunology Cancer
Rubusoside is a diterpene glycoside that is also a sweetener and solubilizer with anti-angiogenic, anti-cancer, anti-obesity, anti-allergic and anti-asthmatic effects. Rubusoside attenuates airway hyperresponsiveness and reduces inflammatory cells in bronchoalveolar lavage fluid (BALF), reducing OVA (HY-W250978)-induced airway inflammation. Rubusoside also prevents palmitic acid-induced lipotoxicity in pancreatic INS-1 cells, reduces the transport of human glucose transporters GLUT-1 and fructose GLUT-5, and inhibits NF-κB and α-amylase (α-amylase) .

HY-Y1883A

Polyethylene glycol mono(4-tert-octylphenyl) ether 20+ Cited Publications	Environmental Pollutants Biochemical Assay Reagents	Infection Cancer
Polyethylene glycol mono(4-tert-octylphenyl) ether is a non-denaturing detergent that solubilizes lipid membranes. Polyethylene glycol mono(4-tert-octylphenyl) ether is commonly used in laboratories and is applied to vaccines at different stages of the manufacturing process. Polyethylene glycol mono(4-tert-octylphenyl) ether is listed as an excipient in certain vaccines including split virus influenza vaccines. Polyethylene glycol mono(4-tert-octylphenyl) ether is a nonionic surfactant. Polyethylene glycol mono(4-tert-octylphenyl) ether induces Apoptosis in prostate and colon cancer cell lines and reduces the infectivity of classic enveloped viruses such as WNV .

HY-W099581

Sulfobetaine-14 2 Publications Verification SB3-14; DMAPS	Biochemical Assay Reagents	Others
Zwittergent 3-14 (DMAPS) is a zwitterionic detergent commonly used in biochemistry and molecular biology for the solubilization and purification of membrane-bound proteins and other hydrophobic biomolecules, which have both hydrophilic and hydrophobic moieties , so that it has good detergency properties, making it suitable for stabilizing membrane proteins in aqueous solutions. In addition, DMAPS has been used in various techniques such as electrophoresis and chromatography for the separation and analysis of biomolecules. The long The hydrocarbon chains provide it with good membrane penetration and solubilization capabilities, while the sulfonate and quaternary ammonium groups ensure water solubility and charge neutrality.

HY-19796

Icomidocholic acid 1 Publications Verification Aramchol; C20-FABAC	Stearoyl-CoA Desaturase (SCD)	Metabolic Disease
Icomidocholic acid (Aramchol) is a lipid molecule synthesized from cholic acid and arachidic acid. Icomidocholic acid is an orally active SCD1 inhibitor and cholesterol solubilizer with antifibrotic effects. Icomidocholic acid can reduce liver fat content, dissolve cholesterol crystals and prevent gallstone formation. Icomidocholic acid can be used in the study of nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH) .

HY-W250168

Polyoxyethylene(10) oleyl ether Polyethylene glycol oleyl ether, average Mn～709; Polyethylene glycol monooleyl ether, n～10	Environmental Pollutants Biochemical Assay Reagents	Others
Polyoxyethylene(10) oleyl ether, also known as POE(10) monooleate, is a nonionic surfactant consisting of a polyethylene glycol chain with 10 ethylene oxide units and an oleic acid residue. It has excellent emulsifying, wetting and dispersing properties, making it suitable for a variety of applications including personal care products and pharmaceutical formulations. POE(10) monooleate is commonly used as a solubilizer to improve the solubility and bioavailability of poorly soluble drugs. Furthermore, it is biodegradable and has low toxicity, making it an environmentally friendly ingredient suitable for various industrial applications.

HY-B1620C

Polyvinylpyrrolidone K17 PVP K17; Polyvidone K17; Povidone K17	Biochemical Assay Reagents	Others
Polyvinylpyrrolidone K17 is one of the polymers in pharmaceutical preparations. Polyvinylpyrrolidone K17 is a versatile excipient for both conventional formulations and novel controlled or targeted delivery systems, serving as a binder, coating agent, suspending agent, pore-former, solubilizer, stabilizer, etc .

HY-Y0873P

PEG10000 Polyethylene glycol 10000	Environmental Pollutants Biochemical Assay Reagents	Others
PEG10000 (Polyethylene glycol 10000) can be used as a solubilizer. PEG10000 is a kind of biological materials or organic compounds that are widely used in life science research .

HY-B1620D

Polyvinylpyrrolidone K25 PVP K25; Polyvidone K25; Povidone K25	Biochemical Assay Reagents	Others
Polyvinylpyrrolidone K25 is a multifunctional synthetic polymer. Polyvinylpyrrolidone K25 is a versatile excipient for both conventional formulations and novel controlled or targeted delivery systems. Polyvinylpyrrolidone K25 is a preferable binder for granules and tablets .

HY-P5366

PEP1	Liposome	Others
PEP1 is an amphipathic α-helical peptide containing 31 residues. The interaction of PEP1 with POPC-supported lipid bilayers (SLBs) is concentration-dependent: at low concentrations, it inserts into SLBs to generate compressive stress; at medium concentrations, it saturates the membrane surface to maintain constant stress; and at high concentrations, it solubilizes SLBs. PEP1 can be used for research on the mechanism of membrane-peptide interactions .

HY-15435A

CHAPS hydrate 4 Publications Verification	Biochemical Assay Reagents Exosomes	Others
CHAPS hydrate is a cholic acid-derived, sulfobetaine-type zwitterionic detergent and micelle-forming agent. CHAPS hydrate exhibits properties of weak cationic or nonionic surfactants in different solution systems, undergoes micellization, and forms small, loose hydrophilic aggregates that are temperature-dependent. CHAPS hydrate stabilizes mononucleosomes under different ionic strengths, reduces nucleosome sequence specificity, promotes sliding of histone cores along DNA, solubilizes Tamm‑Horsfall protein to reduce its interference with urinary exosome isolation, and maintains vesicle structure and the activity of related proteins at the same time. CHAPS hydrate is used to recover native folded fusion proteins, enhance the binding capacity of GST fusion proteins, and restore GST enzyme activity. However, CHAPS hydrate cannot refold proteins denatured by urea, guanidine hydrochloride or heat, nor can it construct the structure of intrinsically disordered proteins. CHAPS hydrate is commonly used in research on the separation and purification of membrane proteins .

HY-Y0537C

Potassium chloride, ≥99.99% trace metals basis Potassium chloride, suitable for the extraction and solubilization of proteins	Environmental Pollutants Biochemical Assay Reagents	Others
Potassium chloride, ≥99.99% trace metals basis (Potassium chloride, suitable for the extraction and solubilization of proteins), is an inorganic salt used in the preparation of phosphate buffers. With very low metal impurity content, it is suitable for protein extraction and dissolution.

HY-W129593

Sorbitan monooctadecanoate Sorbitan monostearate	Environmental Pollutants Biochemical Assay Reagents	Others
Sorbitan monooctadecanoate (Sorbitan monostearate) is a hydrophobic nonionic surfactant. Sorbitan monooctadecanoate can serve as a pharmaceutical excipient, such as an emulsifier, nonionic surfactant, solubilizer, wetting agent, and dispersing/suspending agent .

HY-B1620J

Polyvinylpyrrolidone, average Mw~10000 PVP, average Mw~10000; Polyvidone, average Mw~10000; Povidone, average Mw~10000	Environmental Pollutants Biochemical Assay Reagents	Others
Polyvinylpyrrolidone, average Mw~10000 is a multifunctional synthetic polymer with an average molecular weight of 10000 Da. Polyvinylpyrrolidone, average Mw~10000 is widely used to synthesize nanoparticlesPolyvinylpyrrolidone, average Mw~10000 is a versatile excipient for both conventional formulations and novel controlled or targeted delivery systems, serving as a binder, coating agent, suspending agent, pore-former, solubilizer, stabilizer, etc .

HY-B1620N

Polyvinylpyrrolidone, average Mw～360000 PVP, average Mw～360000; Polyvidone, average Mw～360000; Povidone, average Mw～360000	Environmental Pollutants Biochemical Assay Reagents	Others
Polyvinylpyrrolidone, average Mw~360000 is a multifunctional synthetic polymer with an average molecular weight of 360000 Da. Polyvinylpyrrolidone, average Mw~360000 is widely used to synthesize nanoparticlesPolyvinylpyrrolidone, average Mw~360000 is a versatile excipient for both conventional formulations and novel controlled or targeted delivery systems, serving as a binder, coating agent, suspending agent, pore-former, solubilizer, stabilizer, etc .

HY-W250195

Hexaethylene glycol monotetradecyl ether	Biochemical Assay Reagents	Others
Hexaethylene glycol monotetradecyl ether is a kind of nonionic surfactant with hydrophilic head and lipophilic tail. It belongs to the class of polyethylene glycol (PEG) ethers and is widely used in different industrial and research applications. Due to its unique properties, Hexaethylene glycol monotetradecyl ether is commonly used in lotions, detergents and solubilizers. It is particularly useful in the study of membrane proteins and can be used to stabilize and solubilize proteins for use in structural analysis techniques. Due to its moisturizing and emulsifying properties, Hexaethylene glycol monotetradecyl ether is also used in personal care and cosmetics.

HY-W040201

CHAPSO 3-[3-(Cholamidopropyl)dimethylammonio]-2-hydroxy-1-propanesulfonate	Biochemical Assay Reagents	Others
CHAPSO is a bile derivative. CHAPSO reduces protein adsorption, improves the cryo-EM imaging quality. CHAPSO can be used as a detergent, or as the membrane protein solubilization and reconstruction reagent in membrane protein structural studies .

HY-W250166

Polyoxyethylene tridecyl ether	Environmental Pollutants Biochemical Assay Reagents	Others
Poly(ethylene glycol) (12) tridecyl ether is a nonionic surfactant belonging to the family of ethoxylated fatty alcohols. It is commonly used as an emulsifier, solubilizer, and wetting agent in a variety of industrial and personal care products. Poly(ethylene glycol)(12) tridecyl ether has various properties that make it suitable for these applications, including its low toxicity, high solubility in water and organic solvents, and ability to stabilize emulsions. In addition, it can be used as a raw material for the production of other surfactants and specialty chemicals.

HY-44157

ALS-I	Biochemical Assay Reagents	Neurological Disease
ALS-I, an acid-Liable surfactant, is adopted for in-solution enzymatic digestions, can help to solubilize hydrophobic proteins. ALS-I is significantly enhanced peptide recovery for mass spectrometry (MS) mapping in the study of the proteomes of regenerating rat retina and mouse brain .

HY-D1005F

Poloxamer 182 (L62) PEG-PPG-PEG, 2500(Average Mn)	Environmental Pollutants Biochemical Assay Reagents	Others
Poloxamer 182 (L62) can be used as an excipient, such as Emulsifier, solubilizer, lubricant, etc. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs .

HY-B1620K

Polyvinylpyrrolidone, average Mw~29000 PVP, average Mw~29000; Polyvidone, average Mw~29000; Povidone, average Mw~29000	Environmental Pollutants Biochemical Assay Reagents	Others
Polyvinylpyrrolidone, average Mw~29000 is a multifunctional synthetic polymer with an average molecular weight of 29,000 Da. Polyvinylpyrrolidone, average Mw~29000 is a versatile excipient for both conventional formulations and novel controlled or targeted delivery systems, serving as a binder, coating agent, suspending agent, pore-former, solubilizer, stabilizer, etc .

HY-N2334S

Glycochenodeoxycholic acid-d4 Chenodeoxycholylglycine-d₄	Isotope-Labeled Compounds Endogenous Metabolite Apoptosis	Cancer
Glycochenodeoxycholic acid-d₄ is the deuterium labeled Glycochenodeoxycholic acid. Glycochenodeoxycholic acid (Chenodeoxycholylglycine) is a bile acid formed in the liver from chenodeoxycholate and glycine. It acts as a detergent to solubilize fats for absorption and is itself absorbed. Glycochenodeoxycholic acid (Chenodeoxycholylglycine) induces hepatocyte apoptosis .

HY-D1005B

Poloxamer 237 (F87) 1 Publications Verification PEG-PPG-PEG, 7700 (Average Mn)	Environmental Pollutants	Others
Poloxamer 237 (F87) (PEG-PPG-PEG, 7700 (Average Mn)) is an alcohol substance that acts as an oil-in-water emulsifier and solubilizer. Poloxamer 237 (F87) is used in the research of formulations such as contact lens care solutions and eye drops .

HY-B1620I

Polyvinylpyrrolidone K120 PVP K120; Polyvidone K120; Povidone K120	Environmental Pollutants Biochemical Assay Reagents	Others
Polyvinylpyrrolidone K120 is a multifunctional synthetic polymer with excellent adhesiveness and thickening properties. Polyvinylpyrrolidone K120 is a versatile excipient for both conventional formulations and novel controlled or targeted delivery systems. Polyvinylpyrrolidone K120 can be used to prepare drug-loaded hydrogel patches .

HY-154639

Polyoxyl 20 Cetostearyl Ether	Environmental Pollutants Biochemical Assay Reagents	Others
Polyoxyl 20 Cetostearyl Ether can be used as an excipient, such as Emulsifier and solubilizer for emulsions and creams, etc. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs .

HY-166519

(2-Hydroxypropyl)-α-cyclodextrin (MW 1180) α‐HPCD (MW 1180)	Biochemical Assay Reagents	Others
(2-Hydroxypropyl)-α-cyclodextrin (MW 1180) is a cyclic oligosaccharide derivative that acts as a solubilizer in various experiments.

HY-B1620O

Polyvinylpyrrolidone, average Mw~1300000 PVP, average Mw~1300000; Polyvidone, average Mw~1300000; Povidone, average Mw~1300000	Environmental Pollutants Biochemical Assay Reagents	Others
Polyvinylpyrrolidone, average Mw~1300000 is a multifunctional synthetic polymer with an average molecular weight of 1300000 Da. Polyvinylpyrrolidone, average Mw~1300000 shows the higher viscosity to form the fine polymer network as the molecular sieve .

HY-154630

Polyoxypropylene stearyl ether	Biochemical Assay Reagents	Others
Polyoxypropylene stearyl ether can be used as an excipient, such as surfactant, softener, lubricating, wetting, plasticizing, solubilizing and dispersing properties. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs .

HY-135737

Dicaprylyl carbonate 1 Publications Verification Dioctyl carbonate	Others	Others
Dicaprylyl carbonate, a solid, plant-derived fat, is a dry emollient. Dicaprylyl carbonate has excellent dermatological compatibility and a comprehensive performance profile, such as solubilizing and dispersing ability for sun-care filters .

HY-B1620M

Polyvinylpyrrolidone, average Mw～55000 PVP, average Mw～55000; Polyvidone, average Mw～55000; Povidone, average Mw～55000	Biochemical Assay Reagents	Others
Polyvinylpyrrolidone, average Mw~55000 is a multifunctional synthetic polymer with an average molecular weight of 55000 Da. Polyvinylpyrrolidone, average Mw~55000 is widely used to synthesize nanoparticlesPolyvinylpyrrolidone, average Mw~55000 is a versatile excipient for both conventional formulations and novel controlled or targeted delivery systems, serving as a binder, coating agent, suspending agent, pore-former, solubilizer, stabilizer, etc .

HY-W040217

MEGA-10 N-Oxodecyl meglumine; Decanoyl N-methylglucamide	Environmental Pollutants Biochemical Assay Reagents	Others
MEGA-10 (N-Oxodecyl meglumine) is a nonionic sugar-based surfactant. MEGA-10 sequesters n-alkylbenzenes into its hydrophobic core via micelle formation as a solubilizer .

HY-W250172

Polyethylene glycol tert-octylphenyl ether X-405 (70% in H2O)	Biochemical Assay Reagents	Others
Polyethylene glycol tert-octylphenyl ether X-405 (70% in H2O) is a nonionic surfactant commonly used in a variety of industrial and research applications. Polyethylene glycol tert-octylphenyl ether X-405 (70% in H2O) belongs to the family of polyethylene glycol (PEG) ethers with a hydrophilic head and lipophilic tail and is suitable for use in emulsions, detergents and solubilizers. Polyethylene glycol tert-octylphenyl ether X-405 (70% in H2O) is particularly useful in the study of membrane proteins, where it is used to solubilize and stabilize proteins for structural analysis techniques. It is also used in a variety of other applications, including drug delivery systems, nanotechnology, and diagnostic analysis. Additionally, Polyethylene glycol tert-octylphenyl ether X-405 (70% in H2O) is used in the production of microemulsions, salves and lotions due to its emulsifying and solubilizing properties. However, it can be toxic if ingested or inhaled, so proper handling and safety precautions are required.

HY-D1005A5

Poloxamer 123 (L43) PEG-PPG-PEG, 1850 (Average)	Biochemical Assay Reagents	Others
Poloxamer 123 (L43) (PEG-PPG-PEG, average molecular weight 1850) is a nonionic triblock copolymer of polyoxyethylene-polyoxypropylene-polyoxyethylene with an average molecular weight of 1850. Poloxamer 123 L43 can be used as a surfactant, emulsifier, and solubilizer in cosmetics .

HY-W013076

Tetrakis(decyl)ammonium bromide tetra(decyl)ammonium bromide	Biochemical Assay Reagents	Others
Tetrakis(decyl)ammonium bromide is a compound belonging to the class of quaternary ammonium compounds. It is a salt with cationic properties and is used in various industrial and biomedical applications. Tetrakis(decyl)ammonium bromide is commonly used as an emulsifier, solubilizer and antimicrobial agent in personal care products, cleansers and pharmaceutical formulations. It is also used as a phase transfer catalyst in organic synthesis reactions, facilitating the movement of reactants between immiscible phases.

HY-W099575

Sulfobetaine-16	Biochemical Assay Reagents	Others
3-(Hexadecyldimethylammonio)propane-1-sulfonate is an organic compound belonging to the class of sulfonates. It is a quaternary ammonium surfactant commonly used in various industrial and laboratory applications such as the production of detergents, personal care products and pharmaceuticals. 3-(Hexadecyldimethylammonio)propane-1-sulfonate is surface active and can be used as an emulsifier, foaming agent and wetting agent. In addition, it is used as a solubilizer in protein purification and as a surfactant in chromatography.

HY-Y0850U5

PVA (Mw 27000, 98-99% hydrolyzed, ~600 polymerization) Polyvinyl alcohol (Mw 27000, 98-99% hydrolyzed, ~600 polymerization); Poly(Ethenol) (Mw 27000, 98-99% hydrolyzed, ~600 polymerization)	Biochemical Assay Reagents Fungal	Infection
PVA (Polyvinyl alcohol) (Mw 27000, 98-99% hydrolyzed, ~600 polymerization) is a nonionic ethanol homopolymer with hydrophilicity, water solubility and biodegradability. PVA (Mw 27000, 98-99% hydrolyzed, ~600 polymerization) exhibits biocompatibility, non-toxicity and non-carcinogenicity, as well as antibacterial activity against Gram-positive bacteria, Gram-negative bacteria and fungal strains. PVA (Mw 27000, 98-99% hydrolyzed, ~600 polymerization) can serve as a solubilizer, stabilizer, mucoadhesive agent and sustained-release agent, and has a synergistic solubilizing effect on voriconazole/sulfobutyl ether β-cyclodextrin complexes. By stabilizing such complexes, PVA (Mw 27000, 98-99% hydrolyzed, ~600 polymerization) forms freeze-thaw hydrogels with high mucoadhesion, sustained drug release and ex vivo corneal permeability. When compounded with hyaluronic acid hydrogels, PVA (Mw 27000, 98-99% hydrolyzed, ~600 polymerization) supports chondrocyte growth in vitro, and also forms complexes with Cu ²⁺, Co ²⁺, Ni ²⁺ and Zn ²⁺ ions. PVA (Mw 27000, 98-99% hydrolyzed, ~600 polymerization) can be used in studies related to fungal keratitis, bacterial infections and fungal infections .

HY-Y1890B

Cremophor EL-10	Biochemical Assay Reagents	Others
Cremophor EL-10 is a nonionic polyoxyethylene castor oil surfactant with multiple functions including organic solubilizer, mixed zinc anode corrosion inhibitor and dendrite growth inhibitor. By forming a physical barrier to block electrolyte contact and constructing oriented hydration channels to reduce the desolvation energy barrier of Zn ²⁺, Cremophor EL-10 achieves a corrosion inhibition efficiency of over 99%. Cremophor EL-10 exerts no significant effects on the mitochondrial activity and cell viability of epithelial cells, making it suitable for in vitro drug delivery and biopharmaceutical research at concentrations ≤10% v/v. However, Cremophor EL-10 may induce sustained non-endothelium-dependent contraction in rat aortic rings and exert concentration-dependent inhibitory effects on acetylcholine-induced endothelium-dependent relaxation responses .

HY-W250176

Polyethylene glycol trimethylnonyl ether	Biochemical Assay Reagents	Others
Polyethylene glycol trimethylnonyl ether, is a nonionic surfactant commonly used in various industrial and research applications. It belongs to the family of polyethylene glycol (PEG) ethers with a hydrophilic head and lipophilic tail and is suitable for use in lotions, detergents and solubilizers. Polyethylene glycol trimethylnonyl ether is particularly useful in protein chemistry, where it is used to solubilize and stabilize proteins, such as membrane proteins, for structural analysis techniques. In addition, Polyethylene glycol trimethylnonyl ether has potential applications in drug delivery and other medical fields due to its ability to interact with and penetrate cell membranes.

Cat. No.	Product Name	Type

HY-101461

Methyl-β-cyclodextrin Maximum Cited Publications 106 Publications Verification Methyl-beta-cyclodextrin	Biochemical Assay Reagents
Methyl-β-cyclodextrin (Methyl-beta-cyclodextrin) is a cyclic heptasaccharide used to deliver hydrophobic agents based on its property of solubilizing non-polar substances. Methyl-β-cyclodextrin is also extensively used as a cholesterol-depleting reagent . Methyl-β-cyclodextrin strongly reduces clathrin-dependent endocytosis . Methyl-β-cyclodextrin blocks cell migrasome formation .

HY-116285

n-Octyl β-D-glucopyranoside 3 Publications Verification	Biochemical Assay Reagents
n-Octyl-β-d-glucopyranoside is a non-ionic detergent, it can be widely used in the research of biotechnical, biochemical applications, solubilization and crystallization of membrane proteins. n-Octyl-β-d-glucopyranoside can completely inhibit cavitation-induced cell lysis in vitro .

HY-Y0873Q

PEG20000 Polyethylene glycol 20000	Biochemical Assay Reagents
PEG20000 (Polyethylene glycol 20000) can be used as a solubilizer. PEG20000 is a kind of biological materials or organic compounds that are widely used in life science research, can be degraded by bacteria .

HY-B1620L

Polyvinylpyrrolidone, average Mw~40000

PVP, average Mw~40000; Polyvidone, average Mw~40000; Povidone, average Mw~40000

Biochemical Assay Reagents

Polyvinylpyrrolidone, average Mw~40000 is a multifunctional synthetic polymer with an average molecular weight of 40,000 Da. Polyvinylpyrrolidone, average Mw~40000 is widely used to synthesize nanoparticles. Polyvinylpyrrolidone, average Mw~40000 is a versatile excipient for both conventional formulations and novel controlled or targeted delivery systems, serving as a binder, coating agent, suspending agent, pore-former, solubilizer, stabilizer, etc .

HY-126403

Ethoxylated hydrogenated castor oil 2 Publications Verification PEG-40 hydrogenated castor oil; Macrogolglycerol hydroxystearate; Castor oil, hydrogenated, polyethoxylated	Biochemical Assay Reagents
Ethoxylated hydrogenated castor oil (PEG-40 hydrogenated castor oil) is a combination of synthetic polyethylene glycol (PEG) with natural castor oil. Ethoxylated hydrogenated castor oil can be used to emulsify and solubilize oil-in-water (o/w) emulsions. Ethoxylated hydrogenated castor oil can be used as a cosolvent in vivo .

HY-Y1883

Polyethylene glycol mono(4-tert-octylphenyl) ether surfactant

20+ Cited Publications

Biochemical Assay Reagents

Polyethylene glycol mono(4-tert-octylphenyl) ether surfactant is a non-denaturing detergent that solubilizes lipid membranes. Polyethylene glycol mono(4-tert-octylphenyl) ether surfactant is commonly used in laboratories and is applied to vaccines at different stages of the manufacturing process. Polyethylene glycol mono(4-tert-octylphenyl) ether surfactant is listed as an excipient in certain vaccines including split virus influenza vaccines. Polyethylene glycol mono(4-tert-octylphenyl) ether surfactant is a nonionic surfactant. Polyethylene glycol mono(4-tert-octylphenyl) ether surfactant induces Apoptosis in prostate and colon cancer cell lines and reduces the infectivity of classic enveloped viruses such as WNV .

HY-137234

DM-β-CD

2,6-Di-O-methyl-β-cyclodextrin

Biochemical Assay Reagents

DM-β-CD (2,6-Di-O-methyl-β-cyclodextrin) is a cyclic molecule consisting of seven glucose units modified with two methyl groups at the 2- and 6-positions. It is usually used as a solubilizer and carrier for poorly soluble drugs in pharmaceutical preparations. Furthermore, it has applications in analytical chemistry, food science, and environmental remediation due to its ability to form clathrates with various guest molecules, such as aromatic compounds, pesticides, and heavy metals.

HY-401424

Cremophor EL-36

Polyoxyethylene(36) Castor Oil; PEG-36 Castor Oil

Biochemical Assay Reagents

Cremophor EL-36 is a non-ionic surfactant, mainly used as a solubilizing carrier for poorly soluble Paclitaxel (HY-B0015). For example, Cremophor EL-36 can enhance the intracellular influx of Etoposide (HY-13629) without affecting drug efflux, and can dose-dependently increase the accumulation of VP-16 in lung adenocarcinoma cells (such as PC-14 and A549), significantly enhancing its cytotoxic effect .

HY-W134422

(1,1,3,3-Tetramethylbutyl)phenyl-polyethylene glycol X-114

2 Publications Verification

Polyoxyethylene octylphenol ether

Biochemical Assay Reagents

(1,1,3,3-Tetramethylbutyl)phenyl-polyethylene glycol X-114 is a surfactant. (1,1,3,3-Tetramethylbutyl)phenyl-polyethylene glycol X-114 is used to solubilize membranes and whole cells. A solution of (1,1,3,3-Tetramethylbutyl)phenyl-polyethylene glycol X-114 is homogeneous at 0 degrees C but separates in an aqueous phase and a detergent phase above 20 degrees C. (1,1,3,3-Tetramethylbutyl)phenyl-polyethylene glycol X-114 can be used in phase separation studies .

HY-B1620E

Polyvinylpyrrolidone K60 PVP K60; Polyvidone K60; Povidone K60	Biochemical Assay Reagents
Polyvinylpyrrolidone K60 is one of the polymers in pharmaceutical preparations. Polyvinylpyrrolidone K60 promotes amorphous dispersion and inhibits crystallization of the drug .

HY-W099581

Sulfobetaine-14

2 Publications Verification

SB3-14; DMAPS

Biochemical Assay Reagents

Zwittergent 3-14 (DMAPS) is a zwitterionic detergent commonly used in biochemistry and molecular biology for the solubilization and purification of membrane-bound proteins and other hydrophobic biomolecules, which have both hydrophilic and hydrophobic moieties , so that it has good detergency properties, making it suitable for stabilizing membrane proteins in aqueous solutions. In addition, DMAPS has been used in various techniques such as electrophoresis and chromatography for the separation and analysis of biomolecules. The long The hydrocarbon chains provide it with good membrane penetration and solubilization capabilities, while the sulfonate and quaternary ammonium groups ensure water solubility and charge neutrality.

HY-W250168

Polyoxyethylene(10) oleyl ether

Polyethylene glycol oleyl ether, average Mn～709; Polyethylene glycol monooleyl ether, n～10

Biochemical Assay Reagents

Polyoxyethylene(10) oleyl ether, also known as POE(10) monooleate, is a nonionic surfactant consisting of a polyethylene glycol chain with 10 ethylene oxide units and an oleic acid residue. It has excellent emulsifying, wetting and dispersing properties, making it suitable for a variety of applications including personal care products and pharmaceutical formulations. POE(10) monooleate is commonly used as a solubilizer to improve the solubility and bioavailability of poorly soluble drugs. Furthermore, it is biodegradable and has low toxicity, making it an environmentally friendly ingredient suitable for various industrial applications.

HY-B1620C

Polyvinylpyrrolidone K17 PVP K17; Polyvidone K17; Povidone K17	Biochemical Assay Reagents
Polyvinylpyrrolidone K17 is one of the polymers in pharmaceutical preparations. Polyvinylpyrrolidone K17 is a versatile excipient for both conventional formulations and novel controlled or targeted delivery systems, serving as a binder, coating agent, suspending agent, pore-former, solubilizer, stabilizer, etc .

HY-Y0873P

PEG10000 Polyethylene glycol 10000	Biochemical Assay Reagents
PEG10000 (Polyethylene glycol 10000) can be used as a solubilizer. PEG10000 is a kind of biological materials or organic compounds that are widely used in life science research .

HY-B1620D

Polyvinylpyrrolidone K25 PVP K25; Polyvidone K25; Povidone K25	Biochemical Assay Reagents
Polyvinylpyrrolidone K25 is a multifunctional synthetic polymer. Polyvinylpyrrolidone K25 is a versatile excipient for both conventional formulations and novel controlled or targeted delivery systems. Polyvinylpyrrolidone K25 is a preferable binder for granules and tablets .

HY-15435A

CHAPS hydrate

4 Publications Verification

Biochemical Assay Reagents

CHAPS hydrate is a cholic acid-derived, sulfobetaine-type zwitterionic detergent and micelle-forming agent. CHAPS hydrate exhibits properties of weak cationic or nonionic surfactants in different solution systems, undergoes micellization, and forms small, loose hydrophilic aggregates that are temperature-dependent. CHAPS hydrate stabilizes mononucleosomes under different ionic strengths, reduces nucleosome sequence specificity, promotes sliding of histone cores along DNA, solubilizes Tamm‑Horsfall protein to reduce its interference with urinary exosome isolation, and maintains vesicle structure and the activity of related proteins at the same time. CHAPS hydrate is used to recover native folded fusion proteins, enhance the binding capacity of GST fusion proteins, and restore GST enzyme activity. However, CHAPS hydrate cannot refold proteins denatured by urea, guanidine hydrochloride or heat, nor can it construct the structure of intrinsically disordered proteins. CHAPS hydrate is commonly used in research on the separation and purification of membrane proteins .

HY-Y0537C

Potassium chloride, ≥99.99% trace metals basis Potassium chloride, suitable for the extraction and solubilization of proteins	Biochemical Assay Reagents
Potassium chloride, ≥99.99% trace metals basis (Potassium chloride, suitable for the extraction and solubilization of proteins), is an inorganic salt used in the preparation of phosphate buffers. With very low metal impurity content, it is suitable for protein extraction and dissolution.

HY-B1620J

Polyvinylpyrrolidone, average Mw~10000

PVP, average Mw~10000; Polyvidone, average Mw~10000; Povidone, average Mw~10000

Biochemical Assay Reagents

Polyvinylpyrrolidone, average Mw~10000 is a multifunctional synthetic polymer with an average molecular weight of 10000 Da. Polyvinylpyrrolidone, average Mw~10000 is widely used to synthesize nanoparticlesPolyvinylpyrrolidone, average Mw~10000 is a versatile excipient for both conventional formulations and novel controlled or targeted delivery systems, serving as a binder, coating agent, suspending agent, pore-former, solubilizer, stabilizer, etc .

HY-B1620N

Polyvinylpyrrolidone, average Mw～360000

PVP, average Mw～360000; Polyvidone, average Mw～360000; Povidone, average Mw～360000

Biochemical Assay Reagents

Polyvinylpyrrolidone, average Mw~360000 is a multifunctional synthetic polymer with an average molecular weight of 360000 Da. Polyvinylpyrrolidone, average Mw~360000 is widely used to synthesize nanoparticlesPolyvinylpyrrolidone, average Mw~360000 is a versatile excipient for both conventional formulations and novel controlled or targeted delivery systems, serving as a binder, coating agent, suspending agent, pore-former, solubilizer, stabilizer, etc .

HY-W250195

Hexaethylene glycol monotetradecyl ether

Biochemical Assay Reagents

Hexaethylene glycol monotetradecyl ether is a kind of nonionic surfactant with hydrophilic head and lipophilic tail. It belongs to the class of polyethylene glycol (PEG) ethers and is widely used in different industrial and research applications. Due to its unique properties, Hexaethylene glycol monotetradecyl ether is commonly used in lotions, detergents and solubilizers. It is particularly useful in the study of membrane proteins and can be used to stabilize and solubilize proteins for use in structural analysis techniques. Due to its moisturizing and emulsifying properties, Hexaethylene glycol monotetradecyl ether is also used in personal care and cosmetics.

HY-W040201

CHAPSO 3-[3-(Cholamidopropyl)dimethylammonio]-2-hydroxy-1-propanesulfonate	Biochemical Assay Reagents
CHAPSO is a bile derivative. CHAPSO reduces protein adsorption, improves the cryo-EM imaging quality. CHAPSO can be used as a detergent, or as the membrane protein solubilization and reconstruction reagent in membrane protein structural studies .

HY-W250166

Polyoxyethylene tridecyl ether

Biochemical Assay Reagents

Poly(ethylene glycol) (12) tridecyl ether is a nonionic surfactant belonging to the family of ethoxylated fatty alcohols. It is commonly used as an emulsifier, solubilizer, and wetting agent in a variety of industrial and personal care products. Poly(ethylene glycol)(12) tridecyl ether has various properties that make it suitable for these applications, including its low toxicity, high solubility in water and organic solvents, and ability to stabilize emulsions. In addition, it can be used as a raw material for the production of other surfactants and specialty chemicals.

HY-D1005F

Poloxamer 182 (L62)

PEG-PPG-PEG, 2500(Average Mn)

Biochemical Assay Reagents

Poloxamer 182 (L62) can be used as an excipient, such as Emulsifier, solubilizer, lubricant, etc. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs .

HY-B1620K

Polyvinylpyrrolidone, average Mw~29000 PVP, average Mw~29000; Polyvidone, average Mw~29000; Povidone, average Mw~29000	Biochemical Assay Reagents
Polyvinylpyrrolidone, average Mw~29000 is a multifunctional synthetic polymer with an average molecular weight of 29,000 Da. Polyvinylpyrrolidone, average Mw~29000 is a versatile excipient for both conventional formulations and novel controlled or targeted delivery systems, serving as a binder, coating agent, suspending agent, pore-former, solubilizer, stabilizer, etc .

HY-D1005B

Poloxamer 237 (F87) 1 Publications Verification PEG-PPG-PEG, 7700 (Average Mn)	Biochemical Assay Reagents
Poloxamer 237 (F87) (PEG-PPG-PEG, 7700 (Average Mn)) is an alcohol substance that acts as an oil-in-water emulsifier and solubilizer. Poloxamer 237 (F87) is used in the research of formulations such as contact lens care solutions and eye drops .

HY-B1620I

Polyvinylpyrrolidone K120 PVP K120; Polyvidone K120; Povidone K120	Biochemical Assay Reagents
Polyvinylpyrrolidone K120 is a multifunctional synthetic polymer with excellent adhesiveness and thickening properties. Polyvinylpyrrolidone K120 is a versatile excipient for both conventional formulations and novel controlled or targeted delivery systems. Polyvinylpyrrolidone K120 can be used to prepare drug-loaded hydrogel patches .

HY-166519

(2-Hydroxypropyl)-α-cyclodextrin (MW 1180) α‐HPCD (MW 1180)	Biochemical Assay Reagents
(2-Hydroxypropyl)-α-cyclodextrin (MW 1180) is a cyclic oligosaccharide derivative that acts as a solubilizer in various experiments.

HY-B1620O

Polyvinylpyrrolidone, average Mw~1300000 PVP, average Mw~1300000; Polyvidone, average Mw~1300000; Povidone, average Mw~1300000	Biochemical Assay Reagents
Polyvinylpyrrolidone, average Mw~1300000 is a multifunctional synthetic polymer with an average molecular weight of 1300000 Da. Polyvinylpyrrolidone, average Mw~1300000 shows the higher viscosity to form the fine polymer network as the molecular sieve .

HY-B1620M

Polyvinylpyrrolidone, average Mw～55000

PVP, average Mw～55000; Polyvidone, average Mw～55000; Povidone, average Mw～55000

Biochemical Assay Reagents

Polyvinylpyrrolidone, average Mw~55000 is a multifunctional synthetic polymer with an average molecular weight of 55000 Da. Polyvinylpyrrolidone, average Mw~55000 is widely used to synthesize nanoparticlesPolyvinylpyrrolidone, average Mw~55000 is a versatile excipient for both conventional formulations and novel controlled or targeted delivery systems, serving as a binder, coating agent, suspending agent, pore-former, solubilizer, stabilizer, etc .

HY-W040217

MEGA-10 N-Oxodecyl meglumine; Decanoyl N-methylglucamide	Biochemical Assay Reagents
MEGA-10 (N-Oxodecyl meglumine) is a nonionic sugar-based surfactant. MEGA-10 sequesters n-alkylbenzenes into its hydrophobic core via micelle formation as a solubilizer .

HY-W250172

Polyethylene glycol tert-octylphenyl ether X-405 (70% in H2O)

Biochemical Assay Reagents

Polyethylene glycol tert-octylphenyl ether X-405 (70% in H2O) is a nonionic surfactant commonly used in a variety of industrial and research applications. Polyethylene glycol tert-octylphenyl ether X-405 (70% in H2O) belongs to the family of polyethylene glycol (PEG) ethers with a hydrophilic head and lipophilic tail and is suitable for use in emulsions, detergents and solubilizers. Polyethylene glycol tert-octylphenyl ether X-405 (70% in H2O) is particularly useful in the study of membrane proteins, where it is used to solubilize and stabilize proteins for structural analysis techniques. It is also used in a variety of other applications, including drug delivery systems, nanotechnology, and diagnostic analysis. Additionally, Polyethylene glycol tert-octylphenyl ether X-405 (70% in H2O) is used in the production of microemulsions, salves and lotions due to its emulsifying and solubilizing properties. However, it can be toxic if ingested or inhaled, so proper handling and safety precautions are required.

HY-D1005A5

Poloxamer 123 (L43) PEG-PPG-PEG, 1850 (Average)	Biochemical Assay Reagents
Poloxamer 123 (L43) (PEG-PPG-PEG, average molecular weight 1850) is a nonionic triblock copolymer of polyoxyethylene-polyoxypropylene-polyoxyethylene with an average molecular weight of 1850. Poloxamer 123 L43 can be used as a surfactant, emulsifier, and solubilizer in cosmetics .

HY-W013076

Tetrakis(decyl)ammonium bromide

tetra(decyl)ammonium bromide

Biochemical Assay Reagents

Tetrakis(decyl)ammonium bromide is a compound belonging to the class of quaternary ammonium compounds. It is a salt with cationic properties and is used in various industrial and biomedical applications. Tetrakis(decyl)ammonium bromide is commonly used as an emulsifier, solubilizer and antimicrobial agent in personal care products, cleansers and pharmaceutical formulations. It is also used as a phase transfer catalyst in organic synthesis reactions, facilitating the movement of reactants between immiscible phases.

HY-W099575

Sulfobetaine-16

Biochemical Assay Reagents

3-(Hexadecyldimethylammonio)propane-1-sulfonate is an organic compound belonging to the class of sulfonates. It is a quaternary ammonium surfactant commonly used in various industrial and laboratory applications such as the production of detergents, personal care products and pharmaceuticals. 3-(Hexadecyldimethylammonio)propane-1-sulfonate is surface active and can be used as an emulsifier, foaming agent and wetting agent. In addition, it is used as a solubilizer in protein purification and as a surfactant in chromatography.

HY-Y0850U5

PVA (Mw 27000, 98-99% hydrolyzed, ~600 polymerization)

Polyvinyl alcohol (Mw 27000, 98-99% hydrolyzed, ~600 polymerization); Poly(Ethenol) (Mw 27000, 98-99% hydrolyzed, ~600 polymerization)

Biochemical Assay Reagents

PVA (Polyvinyl alcohol) (Mw 27000, 98-99% hydrolyzed, ~600 polymerization) is a nonionic ethanol homopolymer with hydrophilicity, water solubility and biodegradability. PVA (Mw 27000, 98-99% hydrolyzed, ~600 polymerization) exhibits biocompatibility, non-toxicity and non-carcinogenicity, as well as antibacterial activity against Gram-positive bacteria, Gram-negative bacteria and fungal strains. PVA (Mw 27000, 98-99% hydrolyzed, ~600 polymerization) can serve as a solubilizer, stabilizer, mucoadhesive agent and sustained-release agent, and has a synergistic solubilizing effect on voriconazole/sulfobutyl ether β-cyclodextrin complexes. By stabilizing such complexes, PVA (Mw 27000, 98-99% hydrolyzed, ~600 polymerization) forms freeze-thaw hydrogels with high mucoadhesion, sustained drug release and ex vivo corneal permeability. When compounded with hyaluronic acid hydrogels, PVA (Mw 27000, 98-99% hydrolyzed, ~600 polymerization) supports chondrocyte growth in vitro, and also forms complexes with Cu ²⁺, Co ²⁺, Ni ²⁺ and Zn ²⁺ ions. PVA (Mw 27000, 98-99% hydrolyzed, ~600 polymerization) can be used in studies related to fungal keratitis, bacterial infections and fungal infections .

HY-Y1890B

Cremophor EL-10

Biochemical Assay Reagents

Cremophor EL-10 is a nonionic polyoxyethylene castor oil surfactant with multiple functions including organic solubilizer, mixed zinc anode corrosion inhibitor and dendrite growth inhibitor. By forming a physical barrier to block electrolyte contact and constructing oriented hydration channels to reduce the desolvation energy barrier of Zn ²⁺, Cremophor EL-10 achieves a corrosion inhibition efficiency of over 99%. Cremophor EL-10 exerts no significant effects on the mitochondrial activity and cell viability of epithelial cells, making it suitable for in vitro drug delivery and biopharmaceutical research at concentrations ≤10% v/v. However, Cremophor EL-10 may induce sustained non-endothelium-dependent contraction in rat aortic rings and exert concentration-dependent inhibitory effects on acetylcholine-induced endothelium-dependent relaxation responses .

HY-W250176

Polyethylene glycol trimethylnonyl ether

Biochemical Assay Reagents

Polyethylene glycol trimethylnonyl ether, is a nonionic surfactant commonly used in various industrial and research applications. It belongs to the family of polyethylene glycol (PEG) ethers with a hydrophilic head and lipophilic tail and is suitable for use in lotions, detergents and solubilizers. Polyethylene glycol trimethylnonyl ether is particularly useful in protein chemistry, where it is used to solubilize and stabilize proteins, such as membrane proteins, for structural analysis techniques. In addition, Polyethylene glycol trimethylnonyl ether has potential applications in drug delivery and other medical fields due to its ability to interact with and penetrate cell membranes.

HY-W099581R

Sulfobetaine-14 (Standard)

SB3-14 (Standard); DMAPS (Standard)

Biochemical Assay Reagents

Sulfobetaine-14 (Standard) is the analytical standard of Sulfobetaine-14. This product is intended for research and analytical applications. Zwittergent 3-14 (DMAPS) is a zwitterionic detergent commonly used in biochemistry and molecular biology for the solubilization and purification of membrane-bound proteins and other hydrophobic biomolecules, which have both hydrophilic and hydrophobic moieties , so that it has good detergency properties, making it suitable for stabilizing membrane proteins in aqueous solutions. In addition, DMAPS has been used in various techniques such as electrophoresis and chromatography for the separation and analysis of biomolecules. The long The hydrocarbon chains provide it with good membrane penetration and solubilization capabilities, while the sulfonate and quaternary ammonium groups ensure water solubility and charge neutrality.

HY-W127627

Tween 85

Biochemical Assay Reagents

Tween 85 is a nonionic surfactant belonging to the class of ethoxylated sorbitan esters. It is used as an emulsifier and solubilizer in various industries such as pharmaceutical, cosmetic and food. Because of its ability to blend oily and water-based ingredients, Tween 85 is often used in the formulation of creams, lotions and ointments. In addition, it is used as a dispersant for pigments in the production of paints and coatings.

HY-W142692

Dodecyl β-D-glucopyranoside

Biochemical Assay Reagents

Dodecyl β-D-glucopyranoside is a non-ionic detergent and surfactant commonly used to solubilize and purify membrane proteins in biochemical research. Dodecyl β-D-glucopyranoside also interacts with bovine serum albumin (BSA) to quench its intrinsic fluorescence. The critical micelle concentration (CMC) of Dodecyl β-D-glucopyranoside (DG) and DG/BSA complex is 2.0 mM and 2.34 mM, respectively. Micelles can be formed in aqueous solutions above this concentration .

HY-W127401

Triethylene glycol monooctyl ether n-Octyltrioxyethylene	Biochemical Assay Reagents
Triethylene glycol monooctyl ether is a surfactant, C8E3 solubilizes membrane proteins.

HY-W283166

n-Undecyl β-D-maltopyranoside

Biochemical Assay Reagents

n-Undecyl β-D-maltopyranoside is an n-alkyl β-D-maltopyranoside detergent that can be used for solubilization and structural determination of membrane proteins. n-Undecyl β-D-maltopyranoside effectively solubilizes CST from Golgi-enriched fractions of Pichia pastoris, but fails to maintain the functional activity of CST during subsequent partial purification and reconstitution into proteoliposomes. n-Undecyl β-D-maltopyranoside is more suitable for structural analysis studies of membrane proteins rather than functional reconstitution experiments .

HY-W040224

Octyl β-D-thioglucopyranoside	Biochemical Assay Reagents
Octyl β-D-thioglucopyranoside is a non-ionic detergent that can be used in the field of membrane biochemistry. Octyl β-D-thioglucopyranoside has the ability to solubilize E. coli membrane proteins .

HY-W250171

Octaethylene glycol monohexadecyl ether

Polyoxyethylene (10) cetyl ether

Biochemical Assay Reagents

Octaethylene glycol monohexadecyl ether, is a nonionic surfactant commonly used in various industrial and research applications. Octaethylene glycol monohexadecyl ether belongs to the family of polyethylene glycol (PEG) ethers with a hydrophilic head and lipophilic tail, suitable for use in lotions, detergents and solubilizers. Octaethylene glycol monohexadecyl ether is particularly useful in the study of membrane proteins, where it is used to solubilize and stabilize proteins for structural analysis techniques. In addition, Octaethylene glycol monohexadecyl ether has the ability to interact with and penetrate cell membranes, so it has potential applications in drug delivery and other medical fields.

HY-W250181

Octyl thiomaltoside

Octyl β-D-thiomaltopyranoside

Biochemical Assay Reagents

Octyl thiomaltoside (OTM) is a nonionic detergent commonly used in the purification and crystallization of membrane proteins. It belongs to the family of maltoside detergents and has a hydrophilic head group and a lipophilic tail group, enabling it to interact with water-soluble and membrane-bound proteins. OTMs are known for their ability to solubilize integral membrane proteins without disrupting their structure or function, making them an invaluable tool in biochemical and biophysical research. In addition to protein research, OTMs are used in a variety of other applications, including drug delivery systems, nanotechnology, and diagnostic analysis.

HY-W040218

MEGA-8 N-Octanoyl-N-methylglucamine	Biochemical Assay Reagents
MEGA-8 (N-Octanoyl-N-methylglucamine) is a nonionic sugar-based surfactant. MEGA-8 can gently solubilize membrane proteins without easily causing their denaturation. MEGA-8 is a commonly used reagent for the extraction and study of membrane proteins in biochemistry .

HY-136962

ASB-14 Amidosulfobetaine-14	Biochemical Assay Reagents
ASB-14 (Amidosulfobetaine-14) is a zwitterionic amidosulfobetaine surfactant with membrane protein solubilizing. ASB-14 can be used for the preparative extraction and solubilization of proteins .

HY-W250178

Octaethylene glycol monodecyl ether

Biochemical Assay Reagents

Octaethylene glycol monodecyl ether, is a nonionic surfactant commonly used in various industrial and research applications. It belongs to the family of polyethylene glycol (PEG) ethers with a hydrophilic head and lipophilic tail and is suitable for use in lotions, detergents and solubilizers. Octaethylene glycol monodecyl ether is particularly useful in the study of membrane proteins, where it is used to solubilize and stabilize proteins for structural analysis techniques. In addition, Octaethylene glycol monodecyl ether has the ability to interact with and penetrate cell membranes, so it has potential applications in drug delivery and other medical fields.

HY-157883

C7BzO Dimethyl-2-hydroxyethylampropanepropanesulfonate	Biochemical Assay Reagents
C7BzO (Dimethyl-2-hydroxyethylampropanepropanesulfonate) is a potent solubilizing detergent that can be used for samples such as bacteria, mammals, and plants. C7BzO can be used for the extraction of proteins and the preparation of two-dimensional gel electrophoresis samples .

HY-W440898

DSPE-PEG5000-SH	Biochemical Assay Reagents
DSPE-PEG5000-SH is a polyPEG attached DSPE molecule. The lipid tails allow formation of lipid bilayer in water and can be used to solubilize hydrophobic drugs while the hydrophilic core can encapsulate therapeutic agents, such as nuclein acid (mRNA/DNA), protein or peptide.

Cat. No.	Product Name	Target	Research Area

HY-P5366

PEP1	Liposome	Others
PEP1 is an amphipathic α-helical peptide containing 31 residues. The interaction of PEP1 with POPC-supported lipid bilayers (SLBs) is concentration-dependent: at low concentrations, it inserts into SLBs to generate compressive stress; at medium concentrations, it saturates the membrane surface to maintain constant stress; and at high concentrations, it solubilizes SLBs. PEP1 can be used for research on the mechanism of membrane-peptide interactions .

HY-W250166

Polyoxyethylene tridecyl ether	Environmental Pollutants Biochemical Assay Reagents	Others
Poly(ethylene glycol) (12) tridecyl ether is a nonionic surfactant belonging to the family of ethoxylated fatty alcohols. It is commonly used as an emulsifier, solubilizer, and wetting agent in a variety of industrial and personal care products. Poly(ethylene glycol)(12) tridecyl ether has various properties that make it suitable for these applications, including its low toxicity, high solubility in water and organic solvents, and ability to stabilize emulsions. In addition, it can be used as a raw material for the production of other surfactants and specialty chemicals.

HY-P5878

RG33 Peptide	Biochemical Assay Reagents	Metabolic Disease
RG33 Peptide is a diabetes inhibitor that significantly improves glucose clearance in insulin-resistant mice. RG33 Peptide effectively solubilizes lipid vesicles and promotes cholesterol efflux in cultured macrophages. RG33 Peptide is used in research into type 2 diabetes (T2D) .

Cat. No.	Product Name	Target	Research Area	Image

HY-P992157

Anti-APP/Amyloid beta Antibody (3D6) murine version of Bapineuzumab	Amyloid-β	Neurological Disease
Anti-APP/Amyloid beta Antibody (3D6) is an antibody targeting β-amyloid protein (Aβ) containing free Asp1. Anti-APP/Amyloid beta Antibody (3D6) recognizes and binds to the amino acid epitope at positions 1-5 of β-amyloid protein with a free Asp1 residue. Anti-APP/Amyloid beta Antibody (3D6) serves as a detection antibody in immunoblot analysis. Anti-APP/Amyloid beta Antibody (3D6) is applicable to research related to Alzheimer's disease .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N0668

Rubusoside 2 Publications Verification	other families Classification of Application Fields Terpenoids Other Diseases Diterpenoids Plants Disease Research Fields Sweeteners Source Classification Food Research	GLUT Amylases NF-κB
Rubusoside is a diterpene glycoside that is also a sweetener and solubilizer with anti-angiogenic, anti-cancer, anti-obesity, anti-allergic and anti-asthmatic effects. Rubusoside attenuates airway hyperresponsiveness and reduces inflammatory cells in bronchoalveolar lavage fluid (BALF), reducing OVA (HY-W250978)-induced airway inflammation. Rubusoside also prevents palmitic acid-induced lipotoxicity in pancreatic INS-1 cells, reduces the transport of human glucose transporters GLUT-1 and fructose GLUT-5, and inhibits NF-κB and α-amylase (α-amylase) .

HY-135737

Dicaprylyl carbonate 1 Publications Verification Dioctyl carbonate	Natural Products other families Classification of Application Fields Other Diseases Plants Disease Research Fields Source Classification	Others
Dicaprylyl carbonate, a solid, plant-derived fat, is a dry emollient. Dicaprylyl carbonate has excellent dermatological compatibility and a comprehensive performance profile, such as solubilizing and dispersing ability for sun-care filters .

HY-W170614

Citramalic acid	Structural Classification Ketones, Aldehydes, Acids Amaranthaceae Beta vulgaris L. Plants Source Classification	Endogenous Metabolite
Citramalic acid is an organic acid and soil phosphorus-solubilizing agent. Citramalic acid can be secreted by beet roots, and low phosphorus conditions promote its secretion .

HY-N0668R

Rubusoside (Standard)	Structural Classification other families Terpenoids Diterpenoids Plants Source Classification	GLUT Amylases NF-κB Reference Standards
Rubusoside (Standard) is the analytical standard of Rubusoside. This product is intended for research and analytical applications. Rubusoside is a diterpene glycoside that is also a sweetener and solubilizer with anti-angiogenic, anti-cancer, anti-obesity, anti-allergic and anti-asthmatic effects. Rubusoside attenuates airway hyperresponsiveness and reduces inflammatory cells in bronchoalveolar lavage fluid (BALF), reducing OVA (HY-W250978)-induced airway inflammation. Rubusoside also prevents palmitic acid-induced lipotoxicity in pancreatic INS-1 cells, reduces the transport of human glucose transporters GLUT-1 and fructose GLUT-5, and inhibits NF-κB and α-amylase (α-amylase) .

HY-N17984

Hemsloside Ma3	Structural Classification Terpenoids Cucurbitaceae Plants Hemsleya chinensis Cogn. ex Forbes et Hemsl. Pentacyclic Triterpenoids Source Classification	Biochemical Assay Reagents
Hemsloside Ma3 is an anionic surfactant and *solubilizer. Hemsloside Ma3 is an oleanolic acid bisdesmosidic saponin that can be isolated from the rhizomes of Hemsleya macrosperma* and Hemsleya chinensis. Hemsloside Ma3 improves the water solubility of saikosaponin a, a poorly water-soluble monodesmosidic saponin, and its solubilizing effect appears near the critical micelle concentration. At a constant ionic strength, Hemsloside Ma3 exhibits the property of reduced surface tension with the increase in hydrogen ion concentration .

Cat. No.	Product Name	Chemical Structure

HY-N2334S

Glycochenodeoxycholic acid-d4
Glycochenodeoxycholic acid-d₄ is the deuterium labeled Glycochenodeoxycholic acid. Glycochenodeoxycholic acid (Chenodeoxycholylglycine) is a bile acid formed in the liver from chenodeoxycholate and glycine. It acts as a detergent to solubilize fats for absorption and is itself absorbed. Glycochenodeoxycholic acid (Chenodeoxycholylglycine) induces hepatocyte apoptosis .

HY-116285S1

1-O-n-Octyl-β-D-glucopyranoside-d17
1-O-n-Octyl-β-D-glucopyranoside-d₁₇ is the deuterium labeled n-Octyl β-D-glucopyranoside . n-Octyl-β-d-glucopyranoside is a non-ionic detergent, it can be widely used in the research of biotechnical, biochemical applications, solubilization and crystallization of membrane proteins .

HY-W011038S

Hexadecylpyridinium-d5 bromide

Hexadecylpyridinium bromide-d₅ (HDPB-d₅) is the deuterated form of Hexadecylpyridinium bromide. Hexadecylpyridinium bromide (HDPB) is a cationic surfactant. Hexadecylpyridinium bromide can act as a sensitizer and solubilizer, and is a key component in spectrophotometric determination of metal ion reaction systems. Hexadecylpyridinium bromide can be used as a new passivating ligand for the synthesis and stabilization of cesium lead bromide calcium phosphate nanocrystals.

HY-N2334AS

Glycochenodeoxycholic acid-d7 sodium

Glycochenodeoxycholic acid-d₇ (sodium) is the deuterium labeled Glycochenodeoxycholic acid (sodium salt). Glycochenodeoxycholic acid sodium salt (Chenodeoxycholylglycine sodium salt) is a bile acid formed in the liver from chenodeoxycholate and glycine. It acts as a detergent to solubilize fats for absorption and is itself absorbed. Glycochenodeoxycholic acid sodium salt (Chenodeoxycholylglycine sodium salt) induces hepatocyte apoptosis .

HY-138193S

Lauryl maltose neopentyl glycol-d42

Lauryl maltose neopentyl glycol-d₄₂ (LMNG-d₄₂) is the deuterium labeled Lauryl maltose neopentyl glycol (HY-138193). Lauryl maltose neopentyl glycol (LMNG) is a detergent that can solubilize and stabilize membrane proteins. Lauryl maltose neopentyl glycol extracts integral membrane proteins from membranes, and improves substantially the stability of various membrane proteins, including G protein-coupled receptors and respiratory complexes .

Cat. No.	Product Name		Classification

HY-151786

Fmoc-L-Lys(Pentynoyl-DIM)-OH		Azide Alkynes
Fmoc-L-Lys(Pentynoyl-DIM)-OH is a click chemistry reagent containing an azide. Fmoc-L-Lys(Pentynoyl-DIM)-OH can be used as a SPPS building block for the “helping hand” strategy for purification of highly insoluble peptides. Solubilizing residues are attached to the Lys side-chains using Click-chemistry. The solubilizing tag can be removed with 1M hydrazine or hydroxylamine solution . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

HY-151787

Fmoc-L-Lys(N3-Aca-DIM)-OH		Azide
Fmoc-L-Lys(N3-Aca-DIM)-OH is a click chemistry reagent containing an azide group. Used as a SPPS building-block for the “helping hand” strategy for purification of highly insoluble peptides. Solubilizing residues are attached to the Lys side-chains using Click-chemistry. The solubilizing tag can be removed with 1M hydrazine or hydroxylamine solution . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

Cat. No.	Product Name		Classification

HY-126403

Ethoxylated hydrogenated castor oil 2 Publications Verification PEG-40 hydrogenated castor oil; Macrogolglycerol hydroxystearate; Castor oil, hydrogenated, polyethoxylated		Thickeners
Ethoxylated hydrogenated castor oil (PEG-40 hydrogenated castor oil) is a combination of synthetic polyethylene glycol (PEG) with natural castor oil. Ethoxylated hydrogenated castor oil can be used to emulsify and solubilize oil-in-water (o/w) emulsions. Ethoxylated hydrogenated castor oil can be used as a cosolvent in vivo .

HY-W129593

Sorbitan monooctadecanoate Sorbitan monostearate		Emulsifiers Solubilizing Agents Surfactants Suspending Agents
Sorbitan monooctadecanoate (Sorbitan monostearate) is a hydrophobic nonionic surfactant. Sorbitan monooctadecanoate can serve as a pharmaceutical excipient, such as an emulsifier, nonionic surfactant, solubilizer, wetting agent, and dispersing/suspending agent .

HY-D1005F

Poloxamer 182 (L62) PEG-PPG-PEG, 2500(Average Mn)		Emulsifiers Surfactants
Poloxamer 182 (L62) can be used as an excipient, such as Emulsifier, solubilizer, lubricant, etc. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs .

HY-154639

Polyoxyl 20 Cetostearyl Ether		Emulsifiers Solubilizing Agents
Polyoxyl 20 Cetostearyl Ether can be used as an excipient, such as Emulsifier and solubilizer for emulsions and creams, etc. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs .

HY-154630

Polyoxypropylene stearyl ether		Solubilizing Agents Surfactants
Polyoxypropylene stearyl ether can be used as an excipient, such as surfactant, softener, lubricating, wetting, plasticizing, solubilizing and dispersing properties. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs .

HY-154637

Sucrose Stearate		Emulsifiers Solubilizing Agents Surfactants
Sucrose Stearate can be used as an excipient, such as Surfactants, emulsifiers, solubilizers, etc. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs .

HY-W115818

Polyoxyethylene Sorbitan Monostearate		Emulsifiers Solubilizing Agents Surfactants
Polyoxyethylene Sorbitan Monostearate is an ester of the saturated fatty acid stearic acid (C18:0). Polyoxyethylene Sorbitan Monostearate can be used as an excipient, such as surfactant, emulsifier, solubilizer, wetting agent. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs .

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