104 Results for "

solubilizing

" in MedChemExpress (MCE) Product Catalog:
Products (104)

104 Results for "solubilizing" in MCE Product Catalog:

114
114 Publications Verification
Cat. No.: HY-101461
CAS No.: 128446-36-6
Purity:  99.95%
Synonyms: Methyl-beta-cyclodextrin
Methyl-β-cyclodextrin (Methyl-beta-cyclodextrin) is a cyclic heptasaccharide used to deliver hydrophobic agents based on its property of solubilizing non-polar substances. Methyl-β-cyclodextrin is also extensively used as a cholesterol-depleting reagent . Methyl-β-cyclodextrin strongly reduces clathrin-dependent endocytosis . Methyl-β-cyclodextrin blocks cell migrasome formation .
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28
28 Cited Publications
Cat. No.: HY-Y1883
CAS No.: 9002-93-1
Polyethylene glycol mono(4-tert-octylphenyl) ether surfactant is a non-denaturing detergent that solubilizes lipid membranes. Polyethylene glycol mono(4-tert-octylphenyl) ether surfactant is commonly used in laboratories and is applied to vaccines at different stages of the manufacturing process. Polyethylene glycol mono(4-tert-octylphenyl) ether surfactant is listed as an excipient in certain vaccines including split virus influenza vaccines. Polyethylene glycol mono(4-tert-octylphenyl) ether surfactant is a nonionic surfactant. Polyethylene glycol mono(4-tert-octylphenyl) ether surfactant induces Apoptosis in prostate and colon cancer cell lines and reduces the infectivity of classic enveloped viruses such as WNV .
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28
28 Cited Publications
Cat. No.: HY-Y1883A
CAS No.: 9002-93-1
Polyethylene glycol mono(4-tert-octylphenyl) ether is a non-denaturing detergent that solubilizes lipid membranes. Polyethylene glycol mono(4-tert-octylphenyl) ether is commonly used in laboratories and is applied to vaccines at different stages of the manufacturing process. Polyethylene glycol mono(4-tert-octylphenyl) ether is listed as an excipient in certain vaccines including split virus influenza vaccines. Polyethylene glycol mono(4-tert-octylphenyl) ether is a nonionic surfactant. Polyethylene glycol mono(4-tert-octylphenyl) ether induces Apoptosis in prostate and colon cancer cell lines and reduces the infectivity of classic enveloped viruses such as WNV .
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4
4 Cited Publications
Cat. No.: HY-15435
CAS No.: 75621-03-3
Purity:  99.91%
Research Areas:  

Others

CHAPS is a cholic acid-derived, sulfobetaine-type zwitterionic detergent and micelle-forming agent. CHAPS exhibits properties of weak cationic or nonionic surfactants in different solution systems, undergoes micellization, and forms small, loose hydrophilic aggregates that are temperature-dependent. CHAPS stabilizes mononucleosomes under different ionic strengths, reduces nucleosome sequence specificity, promotes sliding of histone cores along DNA, solubilizes Tamm-Horsfall protein to reduce its interference with urinary exosome isolation, and maintains vesicle structure and the activity of related proteins at the same time. CHAPS is used to recover native folded fusion proteins, enhance the binding capacity of GST fusion proteins, and restore GST enzyme activity. However, CHAPS cannot refold proteins denatured by urea, guanidine hydrochloride or heat, nor can it construct the structure of intrinsically disordered proteins. CHAPS is commonly used in research on the separation and purification of membrane proteins .
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4
4 Cited Publications
Cat. No.: HY-15435A
CAS No.: 331717-45-4
Purity:  ≥98.0%
CHAPS hydrate is a cholic acid-derived, sulfobetaine-type zwitterionic detergent and micelle-forming agent. CHAPS hydrate exhibits properties of weak cationic or nonionic surfactants in different solution systems, undergoes micellization, and forms small, loose hydrophilic aggregates that are temperature-dependent. CHAPS hydrate stabilizes mononucleosomes under different ionic strengths, reduces nucleosome sequence specificity, promotes sliding of histone cores along DNA, solubilizes Tamm‑Horsfall protein to reduce its interference with urinary exosome isolation, and maintains vesicle structure and the activity of related proteins at the same time. CHAPS hydrate is used to recover native folded fusion proteins, enhance the binding capacity of GST fusion proteins, and restore GST enzyme activity. However, CHAPS hydrate cannot refold proteins denatured by urea, guanidine hydrochloride or heat, nor can it construct the structure of intrinsically disordered proteins. CHAPS hydrate is commonly used in research on the separation and purification of membrane proteins .
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3
3 Cited Publications
Cat. No.: HY-116285
CAS No.: 29836-26-8
Purity:  99.92%
n-Octyl-β-d-glucopyranoside is a non-ionic detergent, it can be widely used in the research of biotechnical, biochemical applications, solubilization and crystallization of membrane proteins. n-Octyl-β-d-glucopyranoside can completely inhibit cavitation-induced cell lysis in vitro .
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3
3 Cited Publications
Cat. No.: HY-126403
CAS No.: 61788-85-0
Synonyms: PEG-40 hydrogenated castor oil; Macrogolglycerol hydroxystearate; Castor oil, hydrogenated, polyethoxylated
Ethoxylated hydrogenated castor oil (PEG-40 hydrogenated castor oil) is a combination of synthetic polyethylene glycol (PEG) with natural castor oil. Ethoxylated hydrogenated castor oil can be used to emulsify and solubilize oil-in-water (o/w) emulsions. Ethoxylated hydrogenated castor oil can be used as a cosolvent in vivo .
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2
2 Cited Publications
Cat. No.: HY-W134422
CAS No.: 9036-19-5
Synonyms: Polyoxyethylene octylphenol ether
(1,1,3,3-Tetramethylbutyl)phenyl-polyethylene glycol X-114 is a surfactant. (1,1,3,3-Tetramethylbutyl)phenyl-polyethylene glycol X-114 is used to solubilize membranes and whole cells. A solution of (1,1,3,3-Tetramethylbutyl)phenyl-polyethylene glycol X-114 is homogeneous at 0 degrees C but separates in an aqueous phase and a detergent phase above 20 degrees C. (1,1,3,3-Tetramethylbutyl)phenyl-polyethylene glycol X-114 can be used in phase separation studies .
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2
2 Cited Publications
Cat. No.: HY-N0668
CAS No.: 64849-39-4
Rubusoside is a diterpene glycoside that is also a sweetener and solubilizer with anti-angiogenic, anti-cancer, anti-obesity, anti-allergic and anti-asthmatic effects. Rubusoside attenuates airway hyperresponsiveness and reduces inflammatory cells in bronchoalveolar lavage fluid (BALF), reducing OVA (HY-W250978)-induced airway inflammation. Rubusoside also prevents palmitic acid-induced lipotoxicity in pancreatic INS-1 cells, reduces the transport of human glucose transporters GLUT-1 and fructose GLUT-5, and inhibits NF-κB and α-amylase (α-amylase) .
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2
2 Cited Publications
Cat. No.: HY-W099581
CAS No.: 14933-09-6
Synonyms: SB3-14; DMAPS
Zwittergent 3-14 (DMAPS) is a zwitterionic detergent commonly used in biochemistry and molecular biology for the solubilization and purification of membrane-bound proteins and other hydrophobic biomolecules, which have both hydrophilic and hydrophobic moieties , so that it has good detergency properties, making it suitable for stabilizing membrane proteins in aqueous solutions. In addition, DMAPS has been used in various techniques such as electrophoresis and chromatography for the separation and analysis of biomolecules. The long The hydrocarbon chains provide it with good membrane penetration and solubilization capabilities, while the sulfonate and quaternary ammonium groups ensure water solubility and charge neutrality.
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1
1 Cited Publications
Cat. No.: HY-138941
CAS No.: 3055-98-9
Purity:  ≥98.0%
Synonyms: C12E8
Target:  

Influenza Virus

Research Areas:  

Infection

Octaethylene glycol monododecyl ether (C12E8) is an non-ionic detergent that can be used for membrane protein extraction. Octaethylene glycol monododecyl ether can solubilize the viral membrane of intact influenza virus .
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1
1 Cited Publications
Cat. No.: HY-19796
CAS No.: 246529-22-6
Synonyms: Aramchol; C20-FABAC
Research Areas:  

Metabolic Disease

Icomidocholic acid (Aramchol) is a lipid molecule synthesized from cholic acid and arachidic acid. Icomidocholic acid is an orally active SCD1 inhibitor and cholesterol solubilizer with antifibrotic effects. Icomidocholic acid can reduce liver fat content, dissolve cholesterol crystals and prevent gallstone formation. Icomidocholic acid can be used in the study of nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH) .
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1
1 Cited Publications
Cat. No.: HY-D1005B
CAS No.: 9003-11-6
Synonyms: PEG-PPG-PEG, 7700 (Average Mn)
Poloxamer 237 (F87) (PEG-PPG-PEG, 7700 (Average Mn)) is an alcohol substance that acts as an oil-in-water emulsifier and solubilizer. Poloxamer 237 (F87) is used in the research of formulations such as contact lens care solutions and eye drops .
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1
1 Cited Publications
Cat. No.: HY-135737
CAS No.: 1680-31-5
Purity:  ≥98.0%
Synonyms: Dioctyl carbonate
Dicaprylyl carbonate, a solid, plant-derived fat, is a dry emollient. Dicaprylyl carbonate has excellent dermatological compatibility and a comprehensive performance profile, such as solubilizing and dispersing ability for sun-care filters .
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Cat. No.: HY-Y0873Q
CAS No.: 25322-68-3
Synonyms: Polyethylene glycol 20000
PEG20000 (Polyethylene glycol 20000) can be used as a solubilizer. PEG20000 is a kind of biological materials or organic compounds that are widely used in life science research, can be degraded by bacteria .
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Cat. No.: HY-B1620L
CAS No.: 9003-39-8
Synonyms: PVP, average Mw~40000; Polyvidone, average Mw~40000; Povidone, average Mw~40000
Polyvinylpyrrolidone, average Mw~40000 is a multifunctional synthetic polymer with an average molecular weight of 40,000 Da. Polyvinylpyrrolidone, average Mw~40000 is widely used to synthesize nanoparticles. Polyvinylpyrrolidone, average Mw~40000 is a versatile excipient for both conventional formulations and novel controlled or targeted delivery systems, serving as a binder, coating agent, suspending agent, pore-former, solubilizer, stabilizer, etc .
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Cat. No.: HY-E70013
CAS No.: 37288-51-0
Synonyms: endo-1,3:1,4-β-D-Glucanase
Target:  

Endogenous Metabolite

Research Areas:  

Metabolic Disease

Lichenase, Microorganism (endo-1,3:1,4-β-D-Glucanase) is a specific, endo-(1-3),(1-4)-β-D-glucan 4-glucanohydrolase. Lichenase, Microorganism solubilizes β-glucans from cereal grains and gives gluco-oligosaccharides (GOS). Lichenase, Microorganism can be used in the degradation of polysaccharides in the cell walls .
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Cat. No.: HY-137234
CAS No.: 51166-71-3
Purity:  99.9%
Synonyms: 2,6-Di-O-methyl-β-cyclodextrin
DM-β-CD (2,6-Di-O-methyl-β-cyclodextrin) is a cyclic molecule consisting of seven glucose units modified with two methyl groups at the 2- and 6-positions. It is usually used as a solubilizer and carrier for poorly soluble drugs in pharmaceutical preparations. Furthermore, it has applications in analytical chemistry, food science, and environmental remediation due to its ability to form clathrates with various guest molecules, such as aromatic compounds, pesticides, and heavy metals.
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Cat. No.: HY-401424
CAS No.: 61791-12-6
Synonyms: Polyoxyethylene(36) Castor Oil; PEG-36 Castor Oil
Cremophor EL-36 is a non-ionic surfactant, mainly used as a solubilizing carrier for poorly soluble Paclitaxel (HY-B0015). For example, Cremophor EL-36 can enhance the intracellular influx of Etoposide (HY-13629) without affecting drug efflux, and can dose-dependently increase the accumulation of VP-16 in lung adenocarcinoma cells (such as PC-14 and A549), significantly enhancing its cytotoxic effect .
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Cat. No.: HY-B1620E
CAS No.: 9003-39-8
Synonyms: PVP K60; Polyvidone K60; Povidone K60
Polyvinylpyrrolidone K60 is one of the polymers in pharmaceutical preparations. Polyvinylpyrrolidone K60 promotes amorphous dispersion and inhibits crystallization of the drug .
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