Search Result
Results for "
sulfonated
" in MedChemExpress (MCE) Product Catalog:
25
Biochemical Assay Reagents
9
Isotope-Labeled Compounds
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-113329
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Taurocyamine
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Endogenous Metabolite
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Metabolic Disease
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Guanidinoethyl sulfonate (Taurocyamine) is an orally available, blood-brain permeable competitive inhibitor of taurine transporters and a competitive antagonist of glycine receptors (GlyR) (IC50=565 μM). Guanidinoethyl sulfonate has both weak agonist and antagonist effects on GABAA receptors. Guanidinoethyl sulfonate inhibits taurine transmembrane transport and competitively binds to the GlyR ligand binding domain, thereby blocking glycine-mediated chloride influx, and may regulate brain pH to exert neuroprotective effects. Guanidinoethyl sulfonate can be used for neuroprotection studies of ischemic brain injury .
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- HY-W014837
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3-(1-Pyridinio)-1-propanesulfonate
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Biochemical Assay Reagents
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Others
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NDSB-201 consists of a pyridine group attached to a propane chain, which in turn is attached to a sulfonate group. This compound is commonly used as a buffer in biochemical and biological research, especially in electrophoretic applications. It maintains a stable pH in aqueous solutions and has low UV absorption, making it suitable for use in the UV spectrum. Furthermore, due to its ability to form stable complexes with DNA and other biomolecules, 3-(pyridin-1-ium-1-yl)propane-1-sulfonate has been investigated for its potential in drug delivery and genetic research.
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- HY-W250727
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6-(p-Tolylamino)naphthalene-2-sulfonate sodium
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Fluorescent Dye
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Others
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TNS (6-(p-Tolylamino) naphthalene-2-sulfonate) sodium is a fluorescent probe used to detect the conformational state of proteins. TNS sodium binds to the central hydrophobic calyx of β-lactoglobulin (β-LG) to form a 1:1 complex, which stabilizes the folded conformation of β-LG. TNS sodium shows weak fluorescent signals in aqueous solution, but its fluorescence intensity increases significantly upon binding to the hydrophobic domains of proteins, with the maximum excitation wavelength and maximum emission wavelength located at 321 nm and 446 nm, respectively .
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- HY-B0491A
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AC-17
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Adrenergic Receptor
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Cardiovascular Disease
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Carbazochrome sodium sulfonate (AC-17) is a capillary stabiliser and used for the research of haemorrhage. Carbazochrome sodium sulfonate is an antihemorrhagic agent .
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- HY-107929
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Poly(styrenesulfonic acid) calcium salt
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Potassium Channel
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Metabolic Disease
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Calcium polystyrene sulfonate (Poly(styrenesulfonic acid) calcium salt) is an orally active potassium-lowering agent. Calcium polystyrene sulfonate binds potassium in the distal colon in exchange for Ca 2+. Calcium polystyrene sulfonate can be used for the research of hyperkalemia in chronic kidney disease .
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- HY-W043437
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Isopropyl besylate
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Drug Intermediate
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Others
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Isopropyl benzenesulfonate (Isopropyl besylate) is an aromatic sulfonate compound and also a potentially genotoxic impurity .
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- HY-109654
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Reactive Oxygen Species (ROS)
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Metabolic Disease
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Ensulizole is a sulfonated UV absorber and can intense UVB and partial UVA absorption. Ensulizole can damage the DNA through the generation of reactive oxygen species (ROS) upon UV or sunlight irradiation .
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- HY-W250153
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P2Y Receptor
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Cardiovascular Disease
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Adenosine 3'-phosphate 5'-phosphosulfate lithium, an adenine nucleotide derivative, is a selective P2Y1 antagonist with no effect on P2Y2, P2Y4, or P2Y6 receptors. Adenosine 3'-phosphate 5'-phosphosulfate lithium can competitive inhibit ADP-induced platelet aggregation, as well as the ability of ADP to cause shape change and increases in Ca 2+ in platelets, but had no effect on the inhibition of stimulated adenylate cyclase by ADP. Adenosine 3'-phosphate 5'-phosphosulfate lithium is a co-substrate used for the sulfonation of glycans. Adenosine 3'-phosphate 5'-phosphosulfate lithium can be used for Golgi-resident PAP-specific 3'-phosphatase-coupled sulfotransferase assays, which as donor substrate to transfer a sulfonate group .
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- HY-W014792
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- HY-164090
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P2Y Receptor
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Cardiovascular Disease
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Adenosine 3'-phosphate 5'-phosphosulfate, an adenine nucleotide derivative, is a selective P2Y1 antagonist with no effect on P2Y2, P2Y4, or P2Y6 receptors. Adenosine 3'-phosphate 5'-phosphosulfate can competitive inhibit ADP-induced platelet aggregation, as well as the ability of ADP to cause shape change and increases in Ca 2+ in platelets, but had no effect on the inhibition of stimulated adenylate cyclase by ADP. Adenosine 3'-phosphate 5'-phosphosulfate is a co-substrate used for the sulfonation of glycans. Adenosine 3'-phosphate 5'-phosphosulfate can be used for Golgi-resident PAP-specific 3'-phosphatase-coupled sulfotransferase assays, which as donor substrate to transfer a sulfonate group .
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- HY-46846
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Environmental Pollutants
Biochemical Assay Reagents
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Others
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Styrene-divinylbenzene sulfonated copolymer is a cation exchange resin prepared from sulfonic acid group-containing microporous styrene/divinylbenzene (DVB) copolymer. Styrene-divinylbenzene sulfonated copolymer serves as the core matrix material for most bilirubin adsorbents. It also acts as a hydrophilic cell immobilization carrier, whose porous structure provides an ideal environment for microbial growth and biochemical reactions .
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- HY-W099575
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Biochemical Assay Reagents
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Others
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3-(Hexadecyldimethylammonio)propane-1-sulfonate is an organic compound belonging to the class of sulfonates. It is a quaternary ammonium surfactant commonly used in various industrial and laboratory applications such as the production of detergents, personal care products and pharmaceuticals. 3-(Hexadecyldimethylammonio)propane-1-sulfonate is surface active and can be used as an emulsifier, foaming agent and wetting agent. In addition, it is used as a solubilizer in protein purification and as a surfactant in chromatography.
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- HY-W008600
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- HY-W016091
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- HY-167920
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S-Sulfoglutathione
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Endogenous Metabolite
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Cancer
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Glutathione sulfonate (S-Sulfoglutathione) is a multifunctional bioactive compound that inhibits angiogenesis and tumor growth. Glutathione sulfonate is a competitive inhibitor of glutathione S-transferase and is involved in the detoxification process and the binding of a variety of exogenous and endogenous compounds. Glutathione sulfonate acts in the substrate binding site of Escherichia coli glutathione S-transferase, affecting the catalytic mechanism. The structural characteristics of Glutathione sulfonate contribute to its inhibitory effect by hydrogen bonding in the active center of the enzyme .
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- HY-113329R
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Taurocyamine (Standard)
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Endogenous Metabolite
Reference Standards
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Metabolic Disease
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Guanidinoethyl sulfonate (Standard) is the analytical standard of Guanidinoethyl sulfonate. This product is intended for research and analytical applications. Guanidinoethyl sulfonate is an orally available, blood-brain permeable competitive inhibitor of taurine transporters and a competitive antagonist of glycine receptors (GlyR) (IC50=565 μM). Guanidinoethyl sulfonate has both weak agonist and antagonist effects on GABAA receptors. Guanidinoethyl sulfonate inhibits taurine transmembrane transport and competitively binds to the GlyR ligand binding domain, thereby blocking glycine-mediated chloride influx, and may regulate brain pH to exert neuroprotective effects. Guanidinoethyl sulfonate can be used for neuroprotection studies of ischemic brain injury .
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- HY-D1848A
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Fluorescent Dye
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Others
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Sulfo-Cy3-NHS ditriethylamine is a derivative of Cy3 (Cyanine3) (HY-D0822) dye containing sulfonate ions. Sulfo-Cy3-NHS ditriethylamine contains sulfonate ions and has improved water solubility. Sulfo-Cy3-NHS ditriethylamine can label biomolecules containing amine groups, such as proteins, antibodies or peptides.
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- HY-D0968
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Cyanine3
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Fluorescent Dye
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Others
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Cy 3 Non-Sulfonated (Cyanine3) is a fluorescent label for protein and nucleic acid.
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- HY-W110791
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Biochemical Assay Reagents
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Others
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Sodium diphenylamine-4-sulfonate is a chemical indicator commonly used in redox titrations. Its reduced state is colorless and its oxidized state is reddish-purple. Sodium diphenylamine-4-sulfonate is also a quencher and reducing agent. Sodium diphenylamine-4-sulfonate inhibits the electrochemiluminescence of the ruthenium tris(bipyridine) system through energy transfer. Sodium diphenylamine-4-sulfonate participates in the synthesis of nanocrystals .
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- HY-N9422
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P2Y Receptor
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Cardiovascular Disease
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Adenosine 3'-phosphate 5'-phosphosulfate triethylamine, an adenine nucleotide derivative, is a selective P2Y1 antagonist with no effect on P2Y2, P2Y4, or P2Y6 receptors. Adenosine 3'-phosphate 5'-phosphosulfate triethylamine can competitive inhibit ADP-induced platelet aggregation, as well as the ability of ADP to cause shape change and increases in Ca 2+ in platelets, but had no effect on the inhibition of stimulated adenylate cyclase by ADP. Adenosine 3'-phosphate 5'-phosphosulfate triethylamine is a co-substrate used for the sulfonation of glycans. Adenosine 3'-phosphate 5'-phosphosulfate triethylamine can be used for Golgi-resident PAP-specific 3'-phosphatase-coupled sulfotransferase assays, which as donor substrate to transfer a sulfonate group .
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- HY-D2750
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Fluorescent Dye
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Others
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Sulfo-Cy5 Picolyl Azide is a fluorophore featuring a sulfonate group and an azide. Azide groups are click chemistry handles which are reactive towards terminal alkynes and strained cyclooctynes such as BCN or DBCO. Cy5 is a cyanine dye with excitation and emission maxima at 651 nm and 670 nm respectively. The sulfonate group on the Cy5 dye increases this compound’s water solubility.
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- HY-W017224
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Sodium 1-butanesulfonate
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Biochemical Assay Reagents
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Others
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Sodium butane-1-sulfonate (Sodium 1-butanesulfonate) is an ion-pair reagent. Sodium butane-1-sulfonate is often used in combination with tetramethylammonium hydroxide, malonic acid, etc. in reversed-phase ion-pair chromatography, and can improve the separation efficiency of species of elements such as arsenic and selenium .
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- HY-W024881
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2,3,3-Trimethylindolenine-5-sulfonic acid potassium salt
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Drug Intermediate
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Others
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Potassium 2,3,3-trimethylindole-5-sulfonate (2,3,3-Trimethylindolenine-5-sulfonic acid potassium salt) is an indole derivative containing a sodium sulfonate group and is commonly used as a key intermediate in dye synthesis. Potassium 2,3,3-trimethylindole-5-sulfonate can be coupled to peptides, proteins, nucleic acids, RNA, DNA, carbohydrates, polymers, and small molecules via the sulfonyl substituent .
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- HY-101410A
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Symmetric dimethylarginine (p-hydroxyazobenzene-p′-sulfonate); NG,NG'-Dimethyl-L-arginine (p-hydroxyazobenzene-p′-sulfonate)
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Endogenous Metabolite
NO Synthase
NF-κB
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Inflammation/Immunology
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SDMA p-hydroxyazobenzene-p′-sulfonate is the p-hydroxyazobenzene-p′-sulfonate salt form of SDMA (HY-101410). SDMA p-hydroxyazobenzene-p′-sulfonate is an endogenous inhibitor of nitric oxide synthase (NO synthase) activity. SDMA p-hydroxyazobenzene-p′-sulfonate is an activator for NF-κB, and promotes the expression of IL-6 and TNF-α. SDMA p-hydroxyazobenzene-p′-sulfonate is stable in serum and plasma, and can be used as a kidney biomarker of hepatic and renal dysfunction .
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- HY-W009545
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1-Decanesulfonic acid sodium
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Biochemical Assay Reagents
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Others
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Sodium decane-1-sulfonate is an anionic surfactant used for the analysis of organic small molecule compounds by HPLC and ion-pair liquid chromatography.
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- HY-W087892
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Biochemical Assay Reagents
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Others
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Barium diphenylamine-4-sulfonate can be employed as an intermediate in pharmaceutical manufacturing and in chemical research, and serves as a dosing agent in analytical testing .
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- HY-111932
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CDK
GSK-3
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Cancer
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Indirubin-5-sulfonate is a cyclin-dependent kinase (CDK) inhibitor, with IC50 values of 55 nM, 35 nM, 150 nM, 300 nM and 65 nM for CDK1/cyclin B, CDK2/cyclin A, CDK2/cyclin E, CDK4/cyclin D1, and CDK5/p35, respectively . Indirubin-5-sulfonate also shows inhibitory activity against GSK-3β .
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- HY-W016791
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Sodium pentane-1-sulfonate, 98%; NaPS, 98%
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Biochemical Assay Reagents
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Others
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Sodium pentanesulfonate, 98% (Sodium pentane-1-sulfonate, 98%; NaPS, 98%) is an anionic surfactant that can promote the solubility of proteins and membrane proteins. Sodium pentanesulfonate, 98% is a kind of biological materials or organic compounds that are widely used in life science research .
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- HY-W115743
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- HY-D0968B
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Cyanine3 triethylamine
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Fluorescent Dye
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Others
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Cy 3 Non-Sulfonated (Cyanine3) triethylamine is a cyanine (Cy) dye, and a fluorescent label with green channel for protein and nucleic acid. Cy 3 Non-Sulfonated triethylamine is a fluorescent photoproduct of Cyanine5 via photoconversion upon photoexcitation. Cy 3 Non-Sulfonated triethylamine can be used to high-density single-particle tracking in a living cell without using UV illumination and cell-toxic additives (Ex=470 nm; Em=515 nm and 565 nm nm) .
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- HY-D0968A
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Cyanine3 potassium
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Fluorescent Dye
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Cy 3 (Non-Sulfonated) potassium belongs to the cyanine dye series and is a common fluorescent marker for biomolecules that can interact with biomolecules. Cyanine dyes may also bind to double-helical DNA through intercalation and exhibit enhanced fluorescence upon binding.
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- HY-169381
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Bcl-2 Family
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Others
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hMcl-1-IN-1 (Compound 9) is an hMcl-1 inhibitor based on His224 aryl sulfonate fluoride, with an IC50 value of 5.8 nM .
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- HY-W008600R
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Reference Standards
Biochemical Assay Reagents
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Others
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Sodium octane-1-sulfonate (Standard) is the analytical standard of Sodium octane-1-sulfonate. This product is intended for research and analytical applications. Sodium octane-1-sulfonate is an ion-pairing agent that can be used as a buffer in biochemical research and HPLC .
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- HY-W009545R
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1-Decanesulfonic acid sodium (Standard)
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Reference Standards
Biochemical Assay Reagents
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Others
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Sodium decane-1-sulfonate (Standard) is the analytical standard of Sodium decane-1-sulfonate. This product is intended for research and analytical applications. Sodium decane-1-sulfonate is an anionic surfactant used for the analysis of organic small molecule compounds by HPLC and ion-pair liquid chromatography.
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- HY-173534
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AA sulfonate sodium
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Drug Derivative
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Others
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Arachidonic acid sulfonate (AA sulfonate) sodium is a derivative of Arachidonic acid (HY-109590) containing a sulfonate group.
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- HY-B0491AR
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AC-17 (Standard)
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Reference Standards
Adrenergic Receptor
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Cardiovascular Disease
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Carbazochrome (sodium sulfonate) (Standard) is the analytical standard of Carbazochrome (sodium sulfonate). This product is intended for research and analytical applications. Carbazochrome sodium sulfonate (AC-17) is a capillary stabiliser and used for the research of haemorrhage. Carbazochrome sodium sulfonate is an antihemorrhagic agent .
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- HY-N7878
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- HY-13063
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- HY-N1370R
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Sodium Tanshinone IIA sulfonate (Standard); Tanshinone IIA sodium sulfonate (Standard)
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Reference Standards
CRAC Channel
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Cardiovascular Disease
Cancer
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Tanshinone IIA sulfonate (sodium) (Standard) is the analytical standard of Tanshinone IIA sulfonate (sodium). This product is intended for research and analytical applications. Tanshinone IIA sulfonate (sodium) is a derivative of tanshinone IIA, which acts as an inhibitor of store-operated Ca2+ entry (SOCE), and is used to treat cardiovascular disorders.
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- HY-W008974
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Biochemical Assay Reagents
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Others
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3-(Dimethyl(octadecyl)ammonio)propane-1-sulfonate is a class of quaternary ammonium compounds. It is a surfactant and cationic detergent with amphiphilic properties and therefore useful in various industrial and biomedical applications. 3-(Dimethyl(octadecyl)ammonium)propane-1-sulfonate is commonly used as an emulsifier, solubilizer and antimicrobial agent in personal care products, detergents, textiles and pharmaceutical formulations. It is also used as a reagent in analytical chemistry, especially in the analysis of proteins and DNA.
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- HY-166312
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- HY-166304
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- HY-166280
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- HY-166116
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- HY-165809
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- HY-166311
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- HY-166034
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- HY-166275
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- HY-W982688
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- HY-165863
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- HY-166319
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- HY-166063
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- HY-166273
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- HY-165802
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- HY-166148
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- HY-165847
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- HY-W102347S
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Isotope-Labeled Compounds
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Others
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Sodium 2-(acetylthio)ethane-1-sulfonate-1,1,2,2-d4 is the deuterium labeled Sodium 2-(acetylthio)ethanesulfonate (HY-W102347).
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- HY-165910
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- HY-166042
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- HY-165735
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- HY-165834
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- HY-W748361
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Fluorescent Dye
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Others
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Sulfo-Cy3(Me)COOH sodium is a derivative of Cy3 (Cyanine3) (HY-D0822) dye containing sulfonate ions. Trisulfo-Cy3-acid disodium contains sulfonate ions and has improved water solubility.
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- HY-W714694
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Isotope-Labeled Compounds
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Others
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Metolachlor ESA Sodium Salt-d6 is the deuterium labeled Sodium 2-((2-ethyl-6-methylphenyl)(1-methoxypropan-2-yl)amino)-2-oxoethane-1-sulfonate (HY-W714198).
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- HY-142987
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- HY-D2221
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- HY-165736
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- HY-D1866
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Fluorescent Dye
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Others
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Sulfo-Cy7.5 carboxylic acid is a dye derivative of Cyanine 7.5 (Cy7.5) (HY-D0926) with carboxylic acid and sulfonate ion (sulfonate) functional groups. The sulfonate ion increases the water solubility of the compound, making it suitable for use in aqueous solutions. Cy7.5 is a near-infrared fluorescent dye commonly used in biomedical research areas such as biomarkers and cell imaging. Sulfo-Cy7.5 carboxylic acid can be covalently bound to some biomolecules (especially antibodies, proteins, etc.) to track their location and dynamic changes in biological samples.
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- HY-165824
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- HY-D1848
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Fluorescent Dye
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Others
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Sulfo-Cy3-NHS disodium is a derivative of Cy3 (Cyanine3) (HY-D0822) dye containing sulfonate ions. Sulfo-Cy3-NHS disodium contains sulfonate ions and has improved water solubility. Sulfo-Cy3-NHS disodium can label biomolecules containing amine groups, such as proteins, antibodies or peptides.
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- HY-P5834A
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Caspase
Apoptosis
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Inflammation/Immunology
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Boc-AEVD-CHO TFA is a Caspase 8 inhibitor. Boc-AEVD-CHO TFA significantly increases the frequencies of Nocodazole (HY-13520) or methyl methane sulfonate (MMS) induced micronuclei (MN) and micronucleated binucleates (MNCB) in PBMC by inhibiting cell apoptosis. Boc-AEVD-CHO TFA can be used for immune and inflammatory diseases research .
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- HY-W087892R
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Reference Standards
Biochemical Assay Reagents
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Others
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Barium diphenylamine-4-sulfonate (Standard) is the analytical standard of Barium diphenylamine-4-sulfonate. This product is intended for research and analytical applications. Barium diphenylamine-4-sulfonate can be employed as an intermediate in pharmaceutical manufacturing and in chemical research, and serves as a dosing agent in analytical testing .
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- HY-W353787R
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Sodium 4-hydroxybutane-1-sulphonate (Standard)
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Reference Standards
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Sodium 4-hydroxybutane-1-sulfonate (Standard) is the analytical standard of Sodium 4-hydroxybutane-1-sulfonate. This product is intended for research and analytical applications.
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- HY-W012443R
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Reference Standards
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Sodium 3-(trimethylsilyl)propane-1-sulfonate (Standard) is the analytical standard of Sodium 3-(trimethylsilyl)propane-1-sulfonate. This product is intended for research and analytical applications.
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- HY-W089664R
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Reference Standards
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Sodium 4,4'-oxybis(butane-1-sulfonate) (Standard) is the analytical standard of Sodium 4,4'-oxybis(butane-1-sulfonate). This product is intended for research and analytical applications.
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- HY-W755726
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Isotope-Labeled Compounds
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Others
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Sodium 2-((4-fluorophenyl)(isopropyl)amino)-2-oxoethane-1-sulfonate-d7 is deuterium labeled Sodium 2-((4-fluorophenyl)(isopropyl)amino)-2-oxoethane-1-sulfonate .
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- HY-W011350
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- HY-W112088
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MOFs
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Others
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Sodium 5,8-dicarboxynaphthalene-2-sulfonate is a metal-organic framework (MOF).
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- HY-134360A
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(y-AmNS)-ATP sodium
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Fluorescent Dye
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Metabolic Disease
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ATP-1-Aminonaphthalene-5-sulfonate ((y-AmNS)-ATP) sodium is a fluorescent analog of ATP (HY-B2176). ATP-1-Aminonaphthalene-5-sulfonate is a substrate for DNA-dependent RNA polymerase and valyl t-RNA synthetase (Ex/Em = 320/460 nm) .
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- HY-W714703S
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Isotope-Labeled Compounds
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Others
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Sodium 2-((2,6-dimethylphenyl)(2-(methoxy-d3)ethyl)amino)-2-oxoethane-1-sulfonate is deuterium labeled Sodium 2-((2,6-dimethylphenyl)(2-methoxyethyl)amino)-2-oxoethane-1-sulfonate .
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- HY-165704S
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Isotope-Labeled Compounds
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Others
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2-(3-Carbamoyl-1-((6-chloropyridin-3-yl)methyl)ureido)ethane-1-sulfonate (sodium)-d4 is deuterium labeled 2-(3-Carbamoyl-1-((6-chloropyridin-3-yl)methyl)ureido)ethane-1-sulfonate (sodium) .
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- HY-165693S
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Isotope-Labeled Compounds
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Others
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Sodium 2-((2,6-bis(methyl-d3)phenyl-3,4,5-d3)amino)-2-oxoethane-1-sulfonate is deuterium labeled Sodium 2-((2,6-dimethylphenyl)amino)-2-oxoethane-1-sulfonate .
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- HY-W714705S
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Sodium 2-((2-(ethyl-2,2,2-d3)-6-methylphenyl)amino)-2-oxoethane-1-sulfonate
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Isotope-Labeled Compounds
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Others
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(S)-Metolachlor metabolite CGA 368208-d3 sodium salt (Sodium 2-((2-(ethyl-2,2,2-d3)-6-methylphenyl)amino)-2-oxoethane-1-sulfonate) is deuterium labeled Sodium 2-((2-ethyl-6-methylphenyl)amino)-2-oxoethane-1-sulfonate .
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- HY-186168
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- HY-179894
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- HY-166242
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- HY-166234
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- HY-165790
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- HY-166295
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- HY-166255
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- HY-165848
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- HY-166083
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- HY-165921
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- HY-W856374
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MOFs
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Others
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Sodium 3,3',3'',3'''-((ethene-1,1,2,2-tetrayltetrakis(benzene-4,1-diyl))tetrakis(oxy))tetrakis(propane-1-sulfonate) is a metal-organic framework (MOF).
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- HY-W714698
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Isotope-Labeled Compounds
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Others
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Dimethachlor ethane sulfonic acid sodium salt-d6 is the deuterium labeled Sodium 2-((2,6-dimethylphenyl)(2-methoxyethyl)amino)-2-oxoethane-1-sulfonate (HY-W714703).
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- HY-W614180
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Biochemical Assay Reagents
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Others
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3-Amino-2-sulfopropanoic acid is a short molecule featuring a carboxylic acid, a sulfonate group, and a primary amine. The carboxylic acid and the primary amine are free to link this molecule to larger structures while the sulfonate group provides high water solubility to this aliphatic compound.
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- HY-W726709
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2-[(1-Methylethyl)phenylamino-d5]-2-oxoethanesulfonic acid sodium
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Isotope-Labeled Compounds
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Others
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Propachlor ESA-d5 (2-[(1-Methylethyl)phenylamino-d5]-2-oxoethanesulfonic acid) sodiumis deuterium labeled Sodium 2-(isopropyl(phenyl)amino)-2-oxoethane-1-sulfonate .
|
-
- HY-166217
-
-
- HY-W112089
-
|
|
MOFs
|
Others
|
|
Sodium 1,3,5-trimethylbenzene sulfonate is a metal-organic framework (MOF).
|
-
- HY-W456567
-
|
1,4-Dibromo-2,5-bis[3-(sodiosulfo)propoxy]benzene
|
MOFs
|
Others
|
|
Sodium 3,3'-((2,5-dibromo-1,4-phenylene)bis(oxy))bis(propane-1-sulfonate)(1,4-Dibromo-2,5-bis[3-(sodiosulfo)propoxy]benzene) is a metal-organic framework (MOF).
|
-
- HY-181491
-
|
|
Microtubule/Tubulin
EGFR
Akt
mTOR
Ras
Apoptosis
Autophagy
|
Cancer
|
|
Tubulin-IN-64 is a sulfonated styrylquinazoline derivative with high selectivity antitumor activity. Tubulin-IN-64 targets tubulin, inhibits the EGFR/Akt/mTOR and EGFR/Ras signaling pathways, induces cell cycle arrest, apoptosis and autophagy. Tubulin-IN-64 exhibits significant antitumor efficacy in the zebrafish GBM xenograft model. Tubulin-IN-64 can be used for the research on glioblastoma and leukemia .
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-
- HY-N1370
-
|
Sodium Tanshinone IIA sulfonate; Tanshinone IIA sodium sulfonate
|
CRAC Channel
|
Cardiovascular Disease
Cancer
|
|
Tanshinone IIA sulfonate (sodium) is a derivative of tanshinone IIA, which acts as an inhibitor of store-operated Ca 2+ entry (SOCE), and is used to treat cardiovascular disorders.
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-
- HY-D2224
-
|
|
Fluorescent Dye
|
Others
|
|
Sulfo-Cy5.5 dUTP is a dUTP far-infrared fluorescent dye containing sulfonated Cyanine5.5 group .
|
-
- HY-129524
-
|
|
Apoptosis
|
Inflammation/Immunology
|
|
Ethylene dimethane sulfonate is a mild alkylating, non-volatile methanesulfonic diester of ethylene glycol. Ethylene dimethanesulfonate has selective pro-apoptotic effects on LCs .
|
-
- HY-D2387
-
|
|
Fluorescent Dye
|
Others
|
|
Sulfo CY3.5 hydrazide is sulfonated Cy3.5 with good water solubility. λex=591 nm, λem=604 nm.
|
-
- HY-N17544
-
|
|
Drug Derivative
|
Others
|
|
Sodium 14-deoxy-8,9-didehydro andrographolide-12(R)-sulfonate is a natural product that can be found in Andrographis paniculata.
|
-
- HY-Y0006
-
|
2-(Dicyclohexylphosphino)-2',4',6'-triisopropylbiphenyl
|
Biochemical Assay Reagents
|
Others
|
|
XPhos is a dual aryl monophosphine ligand. XPhos is an efficient and stable palladium catalytic ligand. XPhos can be used for amination of aryl sulfonate esters .
|
-
- HY-W800680
-
|
|
Fluorescent Dye
|
Others
|
|
BP Fluor 488 DBCO is a popular labeling dye used in copper-free Click Chemistry reactions. It will react with the azide group in antibody, proteins, peptides, amino-modified oligos, and other target molecules. The dye has an excitation peak at 499 nm and an emission peak at 520 nm. The conjugates are widely used in microscopy, flow cytometry, and other applications. BP Fluor 488 is a pure 5-sulfonated rhodamine molecule and it eliminates the lot-to-lot variation caused by two isomers ratio differences.
|
-
- HY-W781921
-
|
|
Fluorescent Dye
|
Others
|
|
BP Fluor 488 Alkyne is a popular labeling dye used in Click Chemistry reactions. It will react with the azide group in antibody, proteins, peptides, amino-modified oligos, and other target molecules. The dye has an excitation peak at 499 nm and an emission peak at 520 nm. The conjugates are widely used in microscopy, flow cytometry, and other applications. BP Fluor 488 is a pure 5-sulfonated rhodamine molecule and it eliminates the lot-to-lot variation caused by two isomers ratio differences.
|
-
- HY-B1141
-
|
NC-503
|
Amyloid-β
|
Others
|
|
Eprodisate disodium (NC-503) is the orally available disodium salt form of Eprodisate, a negatively charged sulfonated inhibitor of fibrillogenesis, that can be used in the treatment of amyloid A (AA) amyloidosis.
|
-
- HY-D2229
-
|
|
Fluorescent Dye
|
Others
|
|
Sulfo-Cy3.5 amine is sulfonated modified Cy3.5 with good water solubility. λex=591 nm, λem=604 nm .
|
-
- HY-D2239
-
|
|
Fluorescent Dye
|
Others
|
|
Sulfo-Cy3.5 maleimide is sulfonated modified Cy3.5 with good water solubility. λex=591 nm, λem=604 nm .
|
-
- HY-168971
-
|
CP-25
|
IFNAR
STAT
TNF Receptor
Interleukin Related
CXCR
JAK
G Protein-coupled Receptor Kinase (GRK)
|
Inflammation/Immunology
|
|
Paeoniflorin-6′-O-benzene sulfonate (CP-25) is the inhibitor for G protein-coupled receptor kinase 2 (GRK2) that inhibits the translocation of GRK2 to the cell membrane, inhibits JAK1/STAT3 signaling pathway. Paeoniflorin-6′-O-benzene sulfonate inhibits IL-17A/CXCL2-induced proliferation of HaCaT. Paeoniflorin-6′-O-benzene sulfonate reduces the levels of inflammatory factors and chemokines such as IL-17A, IL-17F, IFN-γ, TNF-α, IL-22, IL-23, CXCL2, CXCL3 and CXCL9, alleviates Imiquimod (HY-B0180)-induced psoriasis in mouse model .
|
-
- HY-D1307A
-
|
|
Fluorescent Dye
|
|
|
Sulfo-cyanine7 alkyne potassium is a water-soluble near-infrared dye with a sulfonated terminal alkyne that can be used in copper-catalyzed click chemistry reactions to conjugate with azides in an aqueous environment.
|
-
- HY-D1307
-
|
|
Fluorescent Dye
|
|
|
Sulfo-cyanine7 alkyne is a water-soluble near-infrared dye with a sulfonated terminal alkyne that can be used in copper-catalyzed click chemistry reactions to conjugate with azides in an aqueous environment.
|
-
- HY-B1785
-
|
Sulfosalicylic acid; Sulphosalicylic acid; Salicylsulfonic acid
|
Drug Derivative
|
Cancer
|
|
5-Sulfosalicylic acid is a sulfonated salicylic acid derivative. 5-Sulfosalicylic acid is effective against the breast cancer cell lines, with less toxicity . 5-Sulfosalicylic acid has antioxidant activities .
|
-
- HY-133424A
-
|
|
Fluorescent Dye
|
Others
|
|
Trisulfo-Cy3-acid disodium is a derivative of Cy3 (Cyanine3) dye. Trisulfo-Cy3-acid disodium contains three sulfonate ions and has improved water solubility.
|
-
- HY-D1864
-
|
|
Fluorescent Dye
|
Others
|
|
Sulfo-Cy7.5 dicarboxylic acid is a dye derivative of Cyanine 7.5 (Cy7.5) (HY-D0926) with carboxylic acid and sulfonate functional groups. The sulfonate ion increases the water solubility of the compound, making it suitable for use in aqueous solutions. Cy7.5 is a near-infrared fluorescent dye commonly used in biomedical research areas such as biomarkers and cell imaging. Sulfo-Cy7.5 dicarboxylic acid can be covalently bound to some biomolecules (especially antibodies, proteins, etc.) to track their location and dynamic changes in biological samples.
|
-
- HY-D2752
-
|
|
Fluorescent Dye
|
Others
|
|
Cy5.5 dimethyl is a free non-activated dye and can be used as a non-reactive fluorophore for experiment controls and instrument calibration. It is a non-sulfonated reagent with good solubility in organic solvents and limited aquous solubility.
|
-
- HY-D1690A
-
|
|
Fluorescent Dye
|
Others
|
|
sBADA is a potent green fluorescent dye. sBADA is a sulfonated BODIPY-FL 3-amino-D-alanine. sBADA is used to label peptidoglycans in bacterial cell walls in situ. (λex=490 nm, λem=510 nm) .
|
-
- HY-W741028
-
|
|
Antibiotic
Bacterial
|
Others
|
|
Moxifloxacin N-sulfate disodium is an anionic sulfonate derivative of Moxifloxacin (HY-66011A). Moxifloxacin is an 8-methoxyquinolone antibacterial antibiotic used in the research of acute bacterial sinusitis, acute bacterial exacerbations of chronic bronchitis, and infectious pneumonia .
|
-
- HY-D2487
-
|
|
Fluorescent Dye
|
Others
|
|
Sulfo Cy5 bis COOH is a derivative of Cy5 (HY-D0821) dye containing sulfonate ions. Sulfo Cy5 bis COOH contains carboxyl groups, which can condense ammonia to form covalent bonds.
|
-
- HY-D2492
-
|
|
Fluorescent Dye
|
Others
|
|
Sulfo Cy7 bis-COOH is a derivative of Cy7 (HY-D0825) dye containing sulfonate ions. Sulfo Cy7 bis-COOH contains carboxyl groups, which can condense ammonia to form covalent bonds.
|
-
- HY-B0812
-
|
SSA dihydrate
|
Biochemical Assay Reagents
|
Cancer
|
|
5-Sulfosalicylic acid dihydrate is a sulfonated salicylic acid derivative. 5-Sulfosalicylic acid dihydrate is effective against the breast cancer cell line, MCF-7, with less toxicity . 5-Sulfosalicylic acid dihydrate has antioxidant activities .
|
-
- HY-D2770
-
|
|
Fluorescent Dye
|
Others
|
|
Cyanine3.5 dimethyl is a non-sulfonated cyanine dye with good solubility in organic solvents and bright fluorescence in the yellow-orange spectrum range. The dye can be used as a non-reactive fluorophore for control experiments, calibration, and other technical applications.
|
-
- HY-D2485
-
|
|
Fluorescent Dye
|
Others
|
|
Sulfo Cy3 bis COOH is a derivative of Cy3 (HY-D0822) dye containing sulfonate ions. Sulfo Cy3 bis COOH contains carboxyl groups, which can condense ammonia to form covalent bonds.
|
-
- HY-D1690
-
|
|
Fluorescent Dye
|
Others
|
|
sBADA TFA is a potent green fluorescent dye. sBADA TFA is a sulfonated BODIPY-FL 3-amino-D-alanine. sBADA TFA is used to label peptidoglycans in bacterial cell walls in situ. (λex=490 nm, λem=510 nm) .
|
-
- HY-129524R
-
|
|
Apoptosis
Reference Standards
|
Inflammation/Immunology
|
|
Ethylene dimethanesulfonate (Standard) is the analytical standard of Ethylene dimethanesulfonate. This product is intended for research and analytical applications. Ethylene dimethane sulfonate is a mild alkylating, non-volatile methanesulfonic diester of ethylene glycol. Ethylene dimethanesulfonate has selective pro-apoptotic effects on LCs .
|
-
- HY-D1859
-
|
|
Fluorescent Dye
|
Others
|
|
Sulfo-Cy7.5 alkyne is a dye derivative of Cyanine 7.5 (Cy7.5) (HY-D0926) containing a sulfonate ion and an alkyne functional group. The sulfonate ion increases the water solubility of the compound, making it suitable for use in aqueous solutions. Cy7.5 is a near-infrared fluorescent dye commonly used for biolabeling and cell imaging. The alkyne functionality of Sulfo-Cy7.5 alkyne can react with molecules containing the azide functionality to form covalent bonds. Sulfo-Cy7.5 alkyne can bind to biomolecules such as proteins and antibodies to track their location and dynamic changes in biological samples.
|
-
- HY-163436
-
|
|
FXR
Cytochrome P450
RAR/RXR
PPAR
ROR
|
Metabolic Disease
|
|
F44-A13 is an orally active and highly selective farnesoid X receptor (FXR) antagonist with an IC50 value of 1.1 μM. F44-A13 can optimize cholesterol metabolism and reduce its activity by inducing CYP7A1 expression. F44-A13 reduces levels of cholesterol, triglycerides, and low-density lipoprotein cholesterol (LDL-C) in mouse models. F44-A13 can be used in the study of metabolic diseases associated with lipid disorders .
|
-
- HY-D2497
-
|
|
Fluorescent Dye
|
Others
|
|
Sulfo Cy7 bis-SH is a fluorescent dye that contains sulfonated Cyanine7 (Sulfo-CY7) fluorescent dye and thiol (-SH) functional group. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds .
|
-
- HY-D1389
-
|
Sulfo-Cyanine5.5 NHS ester tripotassium
|
Fluorescent Dye
|
Others
|
Sulfo-CY-5.5 NHS ester (Sulfo-Cyanine5.5 NHS ester) tripotassium is an amine-reactive ester of sulfonated far-red Cyanine5.5 fluorophore, which can be used to label antibodies, proteins, etc., as well as for in vivo NIR imaging .
|
-
- HY-109654R
-
|
|
Reference Standards
Reactive Oxygen Species (ROS)
|
Metabolic Disease
|
|
Ensulizole (Standard) is the analytical standard of Ensulizole. This product is intended for research and analytical applications. Ensulizole is a sulfonated UV absorber and can intense UVB and partial UVA absorption. Ensulizole can damage the DNA through the generation of reactive oxygen species (ROS) upon UV or sunlight irradiation .
|
-
- HY-W835383
-
|
|
Fluorescent Dye
|
Others
|
|
Sulfo-Cy5.5-COOH is a sulfonated Cy5.5 fluorescent dye containing a sulfonic acid group and a carboxylic acid group. The fluorescence wavelength of Sulfo-Cy5.5-COOH is in the near-infrared region and has strong penetrating power.
|
-
- HY-W590574
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Propargyl-PEG4-Ms has an alkyne group and a mesylate group. The mesylate group is a sulfonate ester for nucleophilic substitution reactions (SN2). The alkyne group can react with azides via copper catalyzed Click Chemistry reactions. The PEG units help increase the solubility of the molecule in aqueous environments.
|
-
- HY-D2494
-
|
|
Fluorescent Dye
|
Others
|
|
Sulfo Cy7 bis-NHS ester is a derivative of Cy7 (HY-D0825) dye containing sulfonate ions. Sulfo Cy7 bis-NHS ester can be used to label the primary amines (R-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.
|
-
- HY-D2486
-
|
|
Fluorescent Dye
|
Others
|
|
Sulfo Cy3 bis NHS ester is a derivative of Cy3 (HY-D0822) dye containing sulfonate ions. Sulfo Cy3 bis NHS ester can be used to label the primary amines (R-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.
|
-
- HY-106583
-
|
Cinnoxicam; SPA-S-510; Sinartol
|
COX
|
Inflammation/Immunology
|
|
Piroxicam cinnamate (Cinnoxicam) is a cyclooxygenase (COX) inhibitor, with anti-inflammatory activity. Piroxicam cinnamate is stable under gastric conditions, can be used for inflammatory-degenerative osteoarticular diseases, rheumatic disorders, and varicocele (VC) associated oligoasthenospermia research .
|
-
- HY-106583R
-
|
Cinnoxicam (Standard); SPA-S-510 (Standard); Sinartol (Standard)
|
Reference Standards
COX
|
Inflammation/Immunology
|
|
Piroxicam cinnamate (Standard) is the analytical standard of Piroxicam cinnamate (HY-106583). This product is intended for research and analytical applications. Piroxicam cinnamate (Cinnoxicam) is a cyclooxygenase (COX) inhibitor, with anti-inflammatory activity. Piroxicam cinnamate is stable under gastric conditions, can be used for inflammatory-degenerative osteoarticular diseases, rheumatic disorders, and varicocele (VC) associated oligoasthenospermia research .
|
-
- HY-B1785R
-
|
Sulfosalicylic acid (Standard); Sulphosalicylic acid (Standard); Salicylsulfonic acid (Standard)
|
Drug Derivative
Reference Standards
|
Cancer
|
|
5-Sulfosalicylic acid (Standard) is the analytical standard of 5-Sulfosalicylic acid. This product is intended for research and analytical applications. 5-Sulfosalicylic acid is a sulfonated salicylic acid derivative. 5-Sulfosalicylic acid is effective against the breast cancer cell lines, with less toxicity . 5-Sulfosalicylic acid has antioxidant activities .
|
-
- HY-136731
-
|
|
DNA/RNA Synthesis
|
Cancer
|
|
APE1-IN-1 is a potent and blood-brain barrier (BBB) penetrant apurinic/apyrimidinic (AP) endonuclease 1 (APE1) inhibitor with an IC50 value of 2 μM. APE1-IN-1 can potentiate the cytotoxicity of the alkylating agents Methylmethane sulfonate and Temozolomide (HY-17364) to cancer cells .
|
-
- HY-121329
-
|
AMA-1080; Ro 17-2301
|
Penicillin-binding protein (PBP)
Antibiotic
Bacterial
|
Infection
|
|
Carumonam (AMA-1080; Ro 17-2301) is a sulfonated monocyclic β-Lactam Antibiotic, targeting to penicillin-binding protein (PBP). Carumonam exerts highly activity against Enterobacteriaceae, Pseudomonas aeruginosa, and Haemophilus influenzae, while it weakly and even inactively inhibits Streptococcus pneumoniae and Staphylococcus aureus. Carumonam is resistant to beta-lactamase-mediated hydrolysis .
|
-
- HY-W583749
-
|
|
Biochemical Assay Reagents
|
Endocrinology
|
|
6:2 Cl-PFAES is an orally effective alternative to Perfluorooctane sulfonate. 6:2 Cl-PFAES significantly inhibits the growth of zebrafish and induces reproductive toxicity. 6:2 Cl-PFAES reduces the relative weights of epididymis and testis in male BALB/c mice. 6:2 Cl-PFAES can be used in the chrome plating industry .
|
-
- HY-D1635
-
|
Biotin-XX-SSE
|
Fluorescent Dye
Exosomes
|
Infection
|
|
Sulfo-NHS-LC-LC-Biotin (Biotin-XX-SSE), a biotin reagent, is used to label the proteins exposed to the external leaflet of intact exosomes and contains a larger spacer arm between the biotin and amine reactive linker. The size of this linker helps to overcome steric hindrance and increases labeling efficiency at the crowded exosome surface .
|
-
- HY-D1850
-
|
|
Fluorescent Dye
|
Others
|
|
Sulfo-Cy7.5 azide is a Cyanine 7.5 (Cy7.5) (HY-D0926) dye derivative with azide and sulfonate functional groups. The sulfonate ion increases the water solubility of the compound, making it suitable for use in aqueous solutions. Cy7.5 is a near-infrared fluorescent dye commonly used for biolabeling and cell imaging. The azide group of Sulfo-Cy7.5 azide can react chemically with molecules containing alkyne functionality, such as alkyne or cyclooctyne, to form covalent bonds. Therefore, Sulfo-Cy7.5 azide can bind to biomolecules such as proteins and antibodies to track their location and dynamic changes in biological samples. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
|
-
- HY-D2242
-
|
|
Fluorescent Dye
|
Others
|
|
Sulfo-Cy7.5 DBCO is a dye derivative of Cyanine 7.5 (Cy7.5) (HY-D0926) bearing a DBCO group. The sulfonate ion increases the water solubility of the compound, making it suitable for use in aqueous solutions. Sulfo-Cy7.5 DBCO can bind to biomolecules such as proteins and antibodies to track their location and dynamic changes in biological samples .
|
-
- HY-D0823
-
CY3-SE
1 Publications Verification
Sulfo-Cy3 NHS ester; Sulfo Cyanine3 NHS ester
|
Fluorescent Dye
|
Others
|
|
Cy3-SE (Sulfo-Cy3 NHS ester; Sulfo Cyanine3 NHS ester) is a sulfonated cyanine dye-derived fluorescent labeling reagent with λex of about 515 nm and λem of about 568 nm. Cy3-SE can interact with the π-π stacking of biomolecules (e.g., nucleoside monophosphates, proteins), inhibiting the photoisomerization process and increasing the fluorescence quantum yield and lifetime .
|
-
- HY-151759
-
|
|
Fluorescent Dye
|
Cancer
|
|
Sulfo-Cy5-TCO is a water-soluble sulfonated Cy5 fluorescent reagent containing trans-cyclooctene (TCO). Sulfo-Cy5-TCO undergoes an inverse electron demand Diels‑Alder reaction with tetrazine-labeled fixed breast cancer cells to achieve cell labeling. Sulfo-Cy5-TCO is used for fluorescent labeling and imaging of biological samples such as proteins and cells .
|
-
- HY-D1376A
-
|
|
Fluorescent Dye
|
Others
|
|
Sulfo-Cyanine5.5 amine consists of four sulfonate groups and has highly hydrophilic. Sulfo-Cyanine5.5 amine is an amine-containing fluorescent dye, the aliphatic primary amine group can be coupled with various electrophiles (activated esters, epoxides, etc). Sulfo-Cyanine5.5 amine can be used for the research of far red/NIR applications (such as in vivo imaging) and also can be used for enzymatic transamination labeling .
|
-
- HY-D1860
-
|
|
Fluorescent Dye
|
Others
|
|
Cy3 alkyne chloride is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing a sulfonate ion and an alkyne functional group. Cy3 is a fluorescent dye with a fluorescence spectrum typically in the green to orange wavelength range. The alkyne functional group of Cy3 alkyne chloride can react with molecules containing the azide functional group to form covalent bonds. Cy3 alkyne chloride can bind to biological molecules such as proteins and antibodies to track their location and dynamic changes in biological samples.
|
-
- HY-137383
-
|
|
Biochemical Assay Reagents
Reactive Oxygen Species (ROS)
|
Others
|
|
Sulfo-SANPAH is a primary amine-nitrobenzene azide cross-linker. Sulfo-SANPAH improves the functionalization process of PDMS surfaces, is covalently bound to the PAAm gel surface. Sulfo-SANPAH is widely used to crosslink ECM proteins to various substrates, including acrylic-based hydrogels, such as polyacrylamide hydrogels. Sulfo-SANPAH facilitates covalent binding through its negatively charged sulfonate group on its N-hydroxysuccinimide ester ring and a photoactivated phenyl azide group that is highly reactive with nucleophiles and free radicals .
|
-
- HY-W587486
-
|
|
Endogenous Metabolite
Bacterial
|
Neurological Disease
|
|
N‑acetyltaurine is an orally active endogenous sulfonate that is synthesized from taurine and acetate in the renal cortex. N‑acetyltaurine supports bacterial growth as a sole fixed nitrogen or carbon source. N‑acetyltaurine buffers acetyl moieties of mitochondrial acetyl‑CoA in skeletal muscle. N‑acetyltaurine reduces food intake and body weight in obese and lean wild‑type mice in a GFRAL‑dependent manner. N‑acetyltaurine can be used for the research of diet‑induced obesity, hyperacetatemia and diabetes .
|
-
- HY-D1846
-
|
|
Fluorescent Dye
|
Others
|
|
Sulfo-Cy7.5 dimethyl is a dye derivative of Cyanine 7.5 (Cy7.5) (HY-D0926) with a dimethyl group. The sulfonate ion increases the water solubility of the compound, making it suitable for use in aqueous solutions. Cy7.5 is a near-infrared fluorescent dye commonly used for biolabeling and cell imaging. Sulfo-Cy7.5 dimethyl binds to biomolecules such as proteins and antibodies to track their location and dynamic changes in biological samples.
|
-
- HY-W800775
-
|
|
Fluorescent Dye
|
Others
|
|
BP Fluor 647 Alkyne is a bright green-fluorescent dye optimal for use with the 633, 650 nm Argon laser. The alkyne group can react with azides via copper catalyzed Click Chemistry reactions. The dye is water soluble and pH-insensitive from pH 4 to pH 10. The dye has 4 sulfonate groups which make it highly water soluble and cause less aggregation in the aqueous solution. BP Fluor 647 Alkyne is used for protein and antibody labeling, or nucleic acid applications with high labeling density.
|
-
- HY-D2759
-
|
|
Fluorescent Dye
|
Others
|
|
Cyanine3B azide for click chemistry conjugation with terminal alkynes via a copper-catalyzed click reaction or strained cyclooctynes via a copper-free click reaction.
Cyanine3B is a yellow-emitting cyanine dye that is an improved version of the Cyanine3 fluorophore with significantly higher fluorescence quantum yield and photostability. Due to the fixed conformation, Cyanine3B has the highest emission quantum yield compared to other dyes of this wavelength.
This is a non-sulfonated dye that requires an organic co-solvent (DMF, DMSO, or other) for efficient labeling in water.
|
-
- HY-NP186
-
|
|
Biochemical Assay Reagents
|
Cancer
|
|
Helix pomatia Agglutinin is a N-acetylgalactosamine (GalNAc) binding lectin, found in the reproductive gland of a Roman snail. Helix pomatia Agglutinin binds with high affinity (kD = 1.9-2.4 μM) steroid hormones: testosterone and progesterone. Helix pomatia Agglutinin interacts with adenine (kD = 5.4 μM) and arylaminonaphthalene sulfonate TNS (kD = 12 μM). Helix pomatia Agglutinin is commonly used for characterizing, imaging, or targeting glycoconjugates, and is also a very useful tool for glycomics analysis . Helix pomatia Agglutinin can be used for cancer prognosis study .
|
-
- HY-120972
-
|
|
Fluorescent Dye
|
Others
|
|
Pentafluorobenzenesulfonyl fluorescein is a H2O2-selective sensor that can be used to detect H2O2 levels in cells. Pentafluorobenzenesulfonyl fluorescein is generally non-fluorescent, but emits fluorescence when its sulfonyl bond undergoes perhydrolysis by H2O2 . Pentafluorobenzenesulfonyl fluorescein undergoes slight cleavage of its sulfonate ester bond by [Cu (phen)2] 2+, and can detect hydrogen peroxide around the ablation sites of fin tissues and keratinocytes in zebrafish larvae .
|
-
- HY-W099581
-
|
SB3-14; DMAPS
|
Biochemical Assay Reagents
|
Others
|
|
Zwittergent 3-14 (DMAPS) is a zwitterionic detergent commonly used in biochemistry and molecular biology for the solubilization and purification of membrane-bound proteins and other hydrophobic biomolecules, which have both hydrophilic and hydrophobic moieties , so that it has good detergency properties, making it suitable for stabilizing membrane proteins in aqueous solutions. In addition, DMAPS has been used in various techniques such as electrophoresis and chromatography for the separation and analysis of biomolecules. The long The hydrocarbon chains provide it with good membrane penetration and solubilization capabilities, while the sulfonate and quaternary ammonium groups ensure water solubility and charge neutrality.
|
-
- HY-D1375
-
|
|
Fluorescent Dye
|
Others
|
|
Sulfo-Cy5 amine is a dye derivative of Cyanine 5 (Cy5) (HY-D0821) bearing an amine group. The sulfonate ion increases the water solubility of the compound, making it suitable for use in aqueous solutions. Cy5 is a near-infrared fluorescent dye commonly used in biolabeling and cell imaging. The amine functionality of Sulfo-Cy5 amine can react with carboxyl groups to form covalent bonds. Sulfo-Cy5 amine can bind to biomolecules such as proteins and antibodies to track their location and dynamic changes in biological samples.
|
-
- HY-D1272
-
|
Sulfo-Cyanine3 amine
|
Fluorescent Dye
|
Others
|
|
Sulfo-Cy3 amine is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) bearing an amine group. The sulfonate ion increases the water solubility of the compound, making it suitable for use in aqueous solutions. Cy3 is a fluorescent dye with a fluorescence spectrum typically in the green to orange wavelength range. The amine functionality of Sulfo-Cy3 amine can react with carboxyl groups to form covalent bonds. Sulfo-Cy3 amine can bind to biological molecules such as proteins and antibodies to track their location and dynamic changes in biological samples.
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-
- HY-D1862
-
|
|
Fluorescent Dye
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Others
|
|
Cy7.5 alkyne chloride is a dye derivative of Cyanine 7.5 (Cy7.5) (HY-D0926) containing a sulfonate ion and an alkyne functional group. Cy7.5 is a near-infrared fluorescent dye commonly used for biolabeling and cell imaging. The alkyne functional group of Cy7.5 alkyne chloride can react with molecules containing the azide functional group to form covalent bonds. Cy7.5 alkyne chloride can bind to biological molecules such as proteins and antibodies to track their location and dynamic changes in biological samples.
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-
- HY-D1861
-
|
|
Fluorescent Dye
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Others
|
|
Sulfo-Cy3 hydrazide is a Cyanine 3 (Cy3) (HY-D0822) dye derivative with hydrazine functionality. The sulfonate ion increases the water solubility of the compound, making it suitable for use in aqueous solutions. Cy3 is a fluorescent dye with a fluorescence spectrum typically in the green to orange wavelength range. The hydrazide group of Sulfo-Cy3 hydrazide can form hydrazinone coupling with molecules containing aldehydes or ketones to form covalent bonds. Therefore, Cy3 azide plus can bind to biomolecules such as proteins and antibodies to track their location and dynamic changes in biological samples.
|
-
- HY-160824
-
|
|
Elastase
Thrombin
Factor Xa
Factor XI
Factor VIII
|
Inflammation/Immunology
|
|
Neutrophil elastase-IN-7 (Compound 12) is an effective inhibitor of neutrophil elastase (HNE), with an IC50 value of 0.54 μM. Neutrophil elastase-IN-7 also exhibits significant inhibitory activity against various coagulation proteins, with the IC50 values for thrombin, FXa, FXIa, and FXIIIa being 8.2, 12.7, 1.2, and 5.7 μM, respectively. Neutrophil elastase-IN-7 can be used for research on inflammation, innate immune responses, and tissue remodeling .
|
-
- HY-W587486R
-
|
|
Reference Standards
Endogenous Metabolite
Bacterial
|
Neurological Disease
|
|
N-Acetyltaurine (Standard) is the analytical standard of N-Acetyltaurine (HY-W587486). This product is intended for research and analytical applications. N‑acetyltaurine is an orally active endogenous sulfonate that is synthesized from taurine and acetate in the renal cortex. N‑acetyltaurine supports bacterial growth as a sole fixed nitrogen or carbon source. N‑acetyltaurine buffers acetyl moieties of mitochondrial acetyl‑CoA in skeletal muscle. N‑acetyltaurine reduces food intake and body weight in obese and lean wild‑type mice in a GFRAL‑dependent manner. N‑acetyltaurine can be used for the research of diet‑induced obesity, hyperacetatemia and diabetes .
|
-
- HY-D1867
-
|
|
Fluorescent Dye
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Others
|
|
Sulfo-Cy3-PEG2-TCO disodium is a derivative of Cy3 (Cyanine3) (HY-D0822) dye containing sulfonate and TCO groups. The TCO groups of Sulfo-Cy3-PEG2-TCO disodium react with tetrazine functional groups in highly specific click chemistry to form covalent bonds. Thus, Sulfo-Cy3-PEG2-TCO disodium can be covalently bound to some biomolecules (especially antibodies, proteins, etc.) to track their location and dynamic changes in biological samples.
|
-
- HY-D1863
-
|
|
Fluorescent Dye
|
Others
|
|
sulfo-Cy7.5 amine is a dye derivative of Cyanine 7.5 (Cy7.5) (HY-D0926) bearing an amine group. The sulfonate ion increases the water solubility of the compound, making it suitable for use in aqueous solutions. Cy7.5 is a near-infrared fluorescent dye commonly used for biolabeling and cell imaging. The amine functionality of sulfo-Cy7.5 amine can react with carboxyl groups to form covalent bonds. Sulfo-Cy7.5 amine can bind to biomolecules such as proteins and antibodies to track their location and dynamic changes in biological samples.
|
-
- HY-D1376
-
|
|
Fluorescent Dye
|
|
|
Sulfo-Cyanine5.5 amine potassium is a water-soluble cyanine dye suitable for far-red/near-infrared applications such as in vivo imaging. The dye has four sulfonate groups, making it highly hydrophilic and water-soluble. Like other cyanines, sulfo-Cyanine5.5 has an excellent extinction coefficient, making it a bright fluorescent marker in the far-red region. This is an amine-containing fluorescent dye. The amine group is separated from the fluorophore by a relatively long linker that facilitates conjugation. Aliphatic primary amine groups can be coupled with various electrophiles (activated esters, epoxides, etc.) and can also be used for enzymatic transamination labeling.
|
-
- HY-121120
-
|
|
Antibiotic
|
Infection
|
|
Isosulfazecin (iSZ) is a novel β-lactam antibiotic produced by Pseudomonas acidophilus sp., synthesized in a nutrient solution supplemented with glycerol and sodium thiosulfate under aerobic conditions in parallel with bacterial growth. It is purified by chromatography and crystallization from aqueous methanol. Physicochemical analysis determined its molecular formula to be C12H20N4O9S, showing a structure with a β-lactam ring, methoxyl and sulfonate groups. Acid hydrolysis yields L-alanine and D-glutamic acid. iSZ is a diastereomer of sulfadiazine and exhibits moderate activity against both gram-positive and gram-negative bacteria, but potent activity against bacteria resistant to β-lactam antibiotics .
|
-
- HY-W099581R
-
|
SB3-14 (Standard); DMAPS (Standard)
|
Biochemical Assay Reagents
Reference Standards
|
Others
|
|
Sulfobetaine-14 (Standard) is the analytical standard of Sulfobetaine-14. This product is intended for research and analytical applications. Zwittergent 3-14 (DMAPS) is a zwitterionic detergent commonly used in biochemistry and molecular biology for the solubilization and purification of membrane-bound proteins and other hydrophobic biomolecules, which have both hydrophilic and hydrophobic moieties , so that it has good detergency properties, making it suitable for stabilizing membrane proteins in aqueous solutions. In addition, DMAPS has been used in various techniques such as electrophoresis and chromatography for the separation and analysis of biomolecules. The long The hydrocarbon chains provide it with good membrane penetration and solubilization capabilities, while the sulfonate and quaternary ammonium groups ensure water solubility and charge neutrality.
|
-
- HY-175818
-
|
|
Apelin Receptor (APJ)
|
Cancer
|
|
APJ antagonist-1 is an apelin receptor (APJ) antagonist. APJ antagonist-1 shows strong β-arrestin inhibition with an IC50 of 3.1 μM. APJ antagonist-1 selectively inhibits APJ-overexpressing cancer cells and suppresses apelin-induced endothelial cell migration. APJ antagonist-1exhibits high metabolic stability. APJ antagonist-1 can used for the studies of ovarian cancer and tumor angiogenesis .
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-
- HY-W099535
-
|
|
Biochemical Assay Reagents
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Others
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|
Lithium dodecyl sulfate is an anionic hydrocarbon surfactant with both surface tension reduction and interfacial adsorption capabilities. Lithium dodecyl sulfate induces low surface viscosity; it forms micelles in aqueous solutions through entropy-driven (low temperature) and enthalpy-driven (high temperature) mechanisms. When acting synergistically with tetrabutylammonium bromide, Lithium dodecyl sulfate exhibits cloud point behavior due to micelle aggregation and phase separation. Lithium dodecyl sulfate can form an adsorption layer at the air-water interface with quantifiable surface excess and minimum area per molecule, and it has higher equilibrium surface tension and foamability compared to other dodecyl sulfate counterion variants. The foam stability of Lithium dodecyl sulfate above its critical micelle concentration is low, and its dynamic surface tension pattern changes dynamically with bubble frequency .
|
-
- HY-W053507
-
|
3-Methylbenzeneacetic acid
|
Drug Metabolite
Drug Intermediate
|
Others
|
|
m-Tolylacetic acid (3-Methylbenzeneacetic acid) is a hydroaromatic dicarboxylic acids excreted in the urine as metabolite of tolueneacetic acid. m-Tolylacetic acid can be used for drug intermediate for synthesising more complex molecules .
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-
- HY-W250153A
-
|
|
P2Y Receptor
|
Cardiovascular Disease
|
|
Adenosine 3'-phosphate 5'-phosphosulfate lithium hydrate, an adenine nucleotide derivative, is a selective P2Y1 antagonist with no effect on P2Y2, P2Y4, or P2Y6 receptors. Adenosine 3'-phosphate 5'-phosphosulfate lithium hydrate can competitive inhibit ADP-induced platelet aggregation, as well as the ability of ADP to cause shape change and increases in Ca 2+ in platelets, but had no effect on the inhibition of stimulated adenylate cyclase by ADP. Adenosine 3'-phosphate 5'-phosphosulfate lithium hydrate is a co-substrate used for the sulfonation of glycans. Adenosine 3'-phosphate 5'-phosphosulfate lithium hydrate can be used for Golgi-resident PAP-specific 3'-phosphatase-coupled sulfotransferase assays, which as donor substrate to transfer a sulfonate group .
|
-
- HY-D3233
-
|
|
Fluorescent Dye
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Others
|
|
Ctrl-BDPS1 is a BODIPY-based control probe that shows no response to copper ions (exhibiting two emission peaks at 575 nm and 708 nm; the maximum excitation wavelength is at 627 nm). Ctrl-BDPS1 has no fluorescent response to Cu + .
|
-
| Cat. No. |
Product Name |
Type |
-
- HY-D0823
-
CY3-SE
1 Publications Verification
Sulfo-Cy3 NHS ester; Sulfo Cyanine3 NHS ester
|
Fluorescent Dye
|
|
Cy3-SE (Sulfo-Cy3 NHS ester; Sulfo Cyanine3 NHS ester) is a sulfonated cyanine dye-derived fluorescent labeling reagent with λex of about 515 nm and λem of about 568 nm. Cy3-SE can interact with the π-π stacking of biomolecules (e.g., nucleoside monophosphates, proteins), inhibiting the photoisomerization process and increasing the fluorescence quantum yield and lifetime .
|
-
- HY-D1389
-
|
Sulfo-Cyanine5.5 NHS ester tripotassium
|
Fluorescent Dye
|
Sulfo-CY-5.5 NHS ester (Sulfo-Cyanine5.5 NHS ester) tripotassium is an amine-reactive ester of sulfonated far-red Cyanine5.5 fluorophore, which can be used to label antibodies, proteins, etc., as well as for in vivo NIR imaging .
|
-
- HY-D1375
-
|
|
Fluorescent Dye
|
|
Sulfo-Cy5 amine is a dye derivative of Cyanine 5 (Cy5) (HY-D0821) bearing an amine group. The sulfonate ion increases the water solubility of the compound, making it suitable for use in aqueous solutions. Cy5 is a near-infrared fluorescent dye commonly used in biolabeling and cell imaging. The amine functionality of Sulfo-Cy5 amine can react with carboxyl groups to form covalent bonds. Sulfo-Cy5 amine can bind to biomolecules such as proteins and antibodies to track their location and dynamic changes in biological samples.
|
-
- HY-151759
-
|
|
Fluorescent Dye
|
|
Sulfo-Cy5-TCO is a water-soluble sulfonated Cy5 fluorescent reagent containing trans-cyclooctene (TCO). Sulfo-Cy5-TCO undergoes an inverse electron demand Diels‑Alder reaction with tetrazine-labeled fixed breast cancer cells to achieve cell labeling. Sulfo-Cy5-TCO is used for fluorescent labeling and imaging of biological samples such as proteins and cells .
|
-
- HY-D1272
-
|
Sulfo-Cyanine3 amine
|
Fluorescent Dye
|
|
Sulfo-Cy3 amine is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) bearing an amine group. The sulfonate ion increases the water solubility of the compound, making it suitable for use in aqueous solutions. Cy3 is a fluorescent dye with a fluorescence spectrum typically in the green to orange wavelength range. The amine functionality of Sulfo-Cy3 amine can react with carboxyl groups to form covalent bonds. Sulfo-Cy3 amine can bind to biological molecules such as proteins and antibodies to track their location and dynamic changes in biological samples.
|
-
- HY-D1848A
-
|
|
Fluorescent Dye
|
|
Sulfo-Cy3-NHS ditriethylamine is a derivative of Cy3 (Cyanine3) (HY-D0822) dye containing sulfonate ions. Sulfo-Cy3-NHS ditriethylamine contains sulfonate ions and has improved water solubility. Sulfo-Cy3-NHS ditriethylamine can label biomolecules containing amine groups, such as proteins, antibodies or peptides.
|
-
- HY-D1376
-
|
|
Fluorescent Dye
|
|
Sulfo-Cyanine5.5 amine potassium is a water-soluble cyanine dye suitable for far-red/near-infrared applications such as in vivo imaging. The dye has four sulfonate groups, making it highly hydrophilic and water-soluble. Like other cyanines, sulfo-Cyanine5.5 has an excellent extinction coefficient, making it a bright fluorescent marker in the far-red region. This is an amine-containing fluorescent dye. The amine group is separated from the fluorophore by a relatively long linker that facilitates conjugation. Aliphatic primary amine groups can be coupled with various electrophiles (activated esters, epoxides, etc.) and can also be used for enzymatic transamination labeling.
|
-
- HY-D0968
-
|
Cyanine3
|
Fluorescent Dye
|
|
Cy 3 Non-Sulfonated (Cyanine3) is a fluorescent label for protein and nucleic acid.
|
-
- HY-D2750
-
|
|
Fluorescent Dye
|
|
Sulfo-Cy5 Picolyl Azide is a fluorophore featuring a sulfonate group and an azide. Azide groups are click chemistry handles which are reactive towards terminal alkynes and strained cyclooctynes such as BCN or DBCO. Cy5 is a cyanine dye with excitation and emission maxima at 651 nm and 670 nm respectively. The sulfonate group on the Cy5 dye increases this compound’s water solubility.
|
-
- HY-D2487
-
|
|
Fluorescent Dye
|
|
Sulfo Cy5 bis COOH is a derivative of Cy5 (HY-D0821) dye containing sulfonate ions. Sulfo Cy5 bis COOH contains carboxyl groups, which can condense ammonia to form covalent bonds.
|
-
- HY-D2497
-
|
|
Fluorescent Dye
|
|
Sulfo Cy7 bis-SH is a fluorescent dye that contains sulfonated Cyanine7 (Sulfo-CY7) fluorescent dye and thiol (-SH) functional group. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds .
|
-
- HY-D1376A
-
|
|
Fluorescent Dye
|
|
Sulfo-Cyanine5.5 amine consists of four sulfonate groups and has highly hydrophilic. Sulfo-Cyanine5.5 amine is an amine-containing fluorescent dye, the aliphatic primary amine group can be coupled with various electrophiles (activated esters, epoxides, etc). Sulfo-Cyanine5.5 amine can be used for the research of far red/NIR applications (such as in vivo imaging) and also can be used for enzymatic transamination labeling .
|
-
- HY-W800680
-
|
|
Fluorescent Dye
|
|
BP Fluor 488 DBCO is a popular labeling dye used in copper-free Click Chemistry reactions. It will react with the azide group in antibody, proteins, peptides, amino-modified oligos, and other target molecules. The dye has an excitation peak at 499 nm and an emission peak at 520 nm. The conjugates are widely used in microscopy, flow cytometry, and other applications. BP Fluor 488 is a pure 5-sulfonated rhodamine molecule and it eliminates the lot-to-lot variation caused by two isomers ratio differences.
|
-
- HY-D2242
-
|
|
Fluorescent Dye
|
|
Sulfo-Cy7.5 DBCO is a dye derivative of Cyanine 7.5 (Cy7.5) (HY-D0926) bearing a DBCO group. The sulfonate ion increases the water solubility of the compound, making it suitable for use in aqueous solutions. Sulfo-Cy7.5 DBCO can bind to biomolecules such as proteins and antibodies to track their location and dynamic changes in biological samples .
|
-
- HY-D1860
-
|
|
Fluorescent Dye
|
|
Cy3 alkyne chloride is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing a sulfonate ion and an alkyne functional group. Cy3 is a fluorescent dye with a fluorescence spectrum typically in the green to orange wavelength range. The alkyne functional group of Cy3 alkyne chloride can react with molecules containing the azide functional group to form covalent bonds. Cy3 alkyne chloride can bind to biological molecules such as proteins and antibodies to track their location and dynamic changes in biological samples.
|
-
- HY-D0968B
-
|
Cyanine3 triethylamine
|
Fluorescent Dye
|
|
Cy 3 Non-Sulfonated (Cyanine3) triethylamine is a cyanine (Cy) dye, and a fluorescent label with green channel for protein and nucleic acid. Cy 3 Non-Sulfonated triethylamine is a fluorescent photoproduct of Cyanine5 via photoconversion upon photoexcitation. Cy 3 Non-Sulfonated triethylamine can be used to high-density single-particle tracking in a living cell without using UV illumination and cell-toxic additives (Ex=470 nm; Em=515 nm and 565 nm nm) .
|
-
- HY-D0968A
-
|
Cyanine3 potassium
|
Fluorescent Dye
|
|
Cy 3 (Non-Sulfonated) potassium belongs to the cyanine dye series and is a common fluorescent marker for biomolecules that can interact with biomolecules. Cyanine dyes may also bind to double-helical DNA through intercalation and exhibit enhanced fluorescence upon binding.
|
-
- HY-W748361
-
|
|
Fluorescent Dye
|
|
Sulfo-Cy3(Me)COOH sodium is a derivative of Cy3 (Cyanine3) (HY-D0822) dye containing sulfonate ions. Trisulfo-Cy3-acid disodium contains sulfonate ions and has improved water solubility.
|
-
- HY-D2221
-
|
|
Fluorescent Dye
|
|
Sulfo-Cy3 dUTP is a dUTP fluorescent dye containing sulfonated Cyanine3 group.
|
-
- HY-D1866
-
|
|
Fluorescent Dye
|
|
Sulfo-Cy7.5 carboxylic acid is a dye derivative of Cyanine 7.5 (Cy7.5) (HY-D0926) with carboxylic acid and sulfonate ion (sulfonate) functional groups. The sulfonate ion increases the water solubility of the compound, making it suitable for use in aqueous solutions. Cy7.5 is a near-infrared fluorescent dye commonly used in biomedical research areas such as biomarkers and cell imaging. Sulfo-Cy7.5 carboxylic acid can be covalently bound to some biomolecules (especially antibodies, proteins, etc.) to track their location and dynamic changes in biological samples.
|
-
- HY-D1848
-
|
|
Fluorescent Dye
|
|
Sulfo-Cy3-NHS disodium is a derivative of Cy3 (Cyanine3) (HY-D0822) dye containing sulfonate ions. Sulfo-Cy3-NHS disodium contains sulfonate ions and has improved water solubility. Sulfo-Cy3-NHS disodium can label biomolecules containing amine groups, such as proteins, antibodies or peptides.
|
-
- HY-D2224
-
|
|
Fluorescent Dye
|
|
Sulfo-Cy5.5 dUTP is a dUTP far-infrared fluorescent dye containing sulfonated Cyanine5.5 group .
|
-
- HY-D2387
-
|
|
Fluorescent Dye
|
|
Sulfo CY3.5 hydrazide is sulfonated Cy3.5 with good water solubility. λex=591 nm, λem=604 nm.
|
-
- HY-D2229
-
|
|
Fluorescent Dye
|
|
Sulfo-Cy3.5 amine is sulfonated modified Cy3.5 with good water solubility. λex=591 nm, λem=604 nm .
|
-
- HY-D2239
-
|
|
Fluorescent Dye
|
|
Sulfo-Cy3.5 maleimide is sulfonated modified Cy3.5 with good water solubility. λex=591 nm, λem=604 nm .
|
-
- HY-D1307A
-
|
|
Fluorescent Dye
|
|
Sulfo-cyanine7 alkyne potassium is a water-soluble near-infrared dye with a sulfonated terminal alkyne that can be used in copper-catalyzed click chemistry reactions to conjugate with azides in an aqueous environment.
|
-
- HY-D1307
-
|
|
Fluorescent Dye
|
|
Sulfo-cyanine7 alkyne is a water-soluble near-infrared dye with a sulfonated terminal alkyne that can be used in copper-catalyzed click chemistry reactions to conjugate with azides in an aqueous environment.
|
-
- HY-133424A
-
|
|
Fluorescent Dye
|
|
Trisulfo-Cy3-acid disodium is a derivative of Cy3 (Cyanine3) dye. Trisulfo-Cy3-acid disodium contains three sulfonate ions and has improved water solubility.
|
-
- HY-D1864
-
|
|
Fluorescent Dye
|
|
Sulfo-Cy7.5 dicarboxylic acid is a dye derivative of Cyanine 7.5 (Cy7.5) (HY-D0926) with carboxylic acid and sulfonate functional groups. The sulfonate ion increases the water solubility of the compound, making it suitable for use in aqueous solutions. Cy7.5 is a near-infrared fluorescent dye commonly used in biomedical research areas such as biomarkers and cell imaging. Sulfo-Cy7.5 dicarboxylic acid can be covalently bound to some biomolecules (especially antibodies, proteins, etc.) to track their location and dynamic changes in biological samples.
|
-
- HY-D2752
-
|
|
Fluorescent Dye
|
|
Cy5.5 dimethyl is a free non-activated dye and can be used as a non-reactive fluorophore for experiment controls and instrument calibration. It is a non-sulfonated reagent with good solubility in organic solvents and limited aquous solubility.
|
-
- HY-D2770
-
|
|
Fluorescent Dye
|
|
Cyanine3.5 dimethyl is a non-sulfonated cyanine dye with good solubility in organic solvents and bright fluorescence in the yellow-orange spectrum range. The dye can be used as a non-reactive fluorophore for control experiments, calibration, and other technical applications.
|
-
- HY-D1690
-
|
|
Fluorescent Dye
|
|
sBADA TFA is a potent green fluorescent dye. sBADA TFA is a sulfonated BODIPY-FL 3-amino-D-alanine. sBADA TFA is used to label peptidoglycans in bacterial cell walls in situ. (λex=490 nm, λem=510 nm) .
|
-
- HY-D1859
-
|
|
Fluorescent Dye
|
|
Sulfo-Cy7.5 alkyne is a dye derivative of Cyanine 7.5 (Cy7.5) (HY-D0926) containing a sulfonate ion and an alkyne functional group. The sulfonate ion increases the water solubility of the compound, making it suitable for use in aqueous solutions. Cy7.5 is a near-infrared fluorescent dye commonly used for biolabeling and cell imaging. The alkyne functionality of Sulfo-Cy7.5 alkyne can react with molecules containing the azide functionality to form covalent bonds. Sulfo-Cy7.5 alkyne can bind to biomolecules such as proteins and antibodies to track their location and dynamic changes in biological samples.
|
-
- HY-D2494
-
|
|
Fluorescent Dye
|
|
Sulfo Cy7 bis-NHS ester is a derivative of Cy7 (HY-D0825) dye containing sulfonate ions. Sulfo Cy7 bis-NHS ester can be used to label the primary amines (R-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.
|
-
- HY-D1850
-
|
|
Fluorescent Dye
|
|
Sulfo-Cy7.5 azide is a Cyanine 7.5 (Cy7.5) (HY-D0926) dye derivative with azide and sulfonate functional groups. The sulfonate ion increases the water solubility of the compound, making it suitable for use in aqueous solutions. Cy7.5 is a near-infrared fluorescent dye commonly used for biolabeling and cell imaging. The azide group of Sulfo-Cy7.5 azide can react chemically with molecules containing alkyne functionality, such as alkyne or cyclooctyne, to form covalent bonds. Therefore, Sulfo-Cy7.5 azide can bind to biomolecules such as proteins and antibodies to track their location and dynamic changes in biological samples. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
|
-
- HY-D1846
-
|
|
Fluorescent Dye
|
|
Sulfo-Cy7.5 dimethyl is a dye derivative of Cyanine 7.5 (Cy7.5) (HY-D0926) with a dimethyl group. The sulfonate ion increases the water solubility of the compound, making it suitable for use in aqueous solutions. Cy7.5 is a near-infrared fluorescent dye commonly used for biolabeling and cell imaging. Sulfo-Cy7.5 dimethyl binds to biomolecules such as proteins and antibodies to track their location and dynamic changes in biological samples.
|
-
- HY-W800775
-
|
|
Fluorescent Dye
|
|
BP Fluor 647 Alkyne is a bright green-fluorescent dye optimal for use with the 633, 650 nm Argon laser. The alkyne group can react with azides via copper catalyzed Click Chemistry reactions. The dye is water soluble and pH-insensitive from pH 4 to pH 10. The dye has 4 sulfonate groups which make it highly water soluble and cause less aggregation in the aqueous solution. BP Fluor 647 Alkyne is used for protein and antibody labeling, or nucleic acid applications with high labeling density.
|
-
- HY-D2759
-
|
|
Fluorescent Dye
|
|
Cyanine3B azide for click chemistry conjugation with terminal alkynes via a copper-catalyzed click reaction or strained cyclooctynes via a copper-free click reaction.
Cyanine3B is a yellow-emitting cyanine dye that is an improved version of the Cyanine3 fluorophore with significantly higher fluorescence quantum yield and photostability. Due to the fixed conformation, Cyanine3B has the highest emission quantum yield compared to other dyes of this wavelength.
This is a non-sulfonated dye that requires an organic co-solvent (DMF, DMSO, or other) for efficient labeling in water.
|
-
- HY-D1862
-
|
|
Fluorescent Dye
|
|
Cy7.5 alkyne chloride is a dye derivative of Cyanine 7.5 (Cy7.5) (HY-D0926) containing a sulfonate ion and an alkyne functional group. Cy7.5 is a near-infrared fluorescent dye commonly used for biolabeling and cell imaging. The alkyne functional group of Cy7.5 alkyne chloride can react with molecules containing the azide functional group to form covalent bonds. Cy7.5 alkyne chloride can bind to biological molecules such as proteins and antibodies to track their location and dynamic changes in biological samples.
|
-
- HY-D1861
-
|
|
Fluorescent Dye
|
|
Sulfo-Cy3 hydrazide is a Cyanine 3 (Cy3) (HY-D0822) dye derivative with hydrazine functionality. The sulfonate ion increases the water solubility of the compound, making it suitable for use in aqueous solutions. Cy3 is a fluorescent dye with a fluorescence spectrum typically in the green to orange wavelength range. The hydrazide group of Sulfo-Cy3 hydrazide can form hydrazinone coupling with molecules containing aldehydes or ketones to form covalent bonds. Therefore, Cy3 azide plus can bind to biomolecules such as proteins and antibodies to track their location and dynamic changes in biological samples.
|
-
- HY-D1867
-
|
|
Fluorescent Dye
|
|
Sulfo-Cy3-PEG2-TCO disodium is a derivative of Cy3 (Cyanine3) (HY-D0822) dye containing sulfonate and TCO groups. The TCO groups of Sulfo-Cy3-PEG2-TCO disodium react with tetrazine functional groups in highly specific click chemistry to form covalent bonds. Thus, Sulfo-Cy3-PEG2-TCO disodium can be covalently bound to some biomolecules (especially antibodies, proteins, etc.) to track their location and dynamic changes in biological samples.
|
-
- HY-D1863
-
|
|
Fluorescent Dye
|
|
sulfo-Cy7.5 amine is a dye derivative of Cyanine 7.5 (Cy7.5) (HY-D0926) bearing an amine group. The sulfonate ion increases the water solubility of the compound, making it suitable for use in aqueous solutions. Cy7.5 is a near-infrared fluorescent dye commonly used for biolabeling and cell imaging. The amine functionality of sulfo-Cy7.5 amine can react with carboxyl groups to form covalent bonds. Sulfo-Cy7.5 amine can bind to biomolecules such as proteins and antibodies to track their location and dynamic changes in biological samples.
|
-
- HY-D2492
-
|
|
Fluorescent Dye
|
|
Sulfo Cy7 bis-COOH is a derivative of Cy7 (HY-D0825) dye containing sulfonate ions. Sulfo Cy7 bis-COOH contains carboxyl groups, which can condense ammonia to form covalent bonds.
|
-
- HY-D2485
-
|
|
Fluorescent Dye
|
|
Sulfo Cy3 bis COOH is a derivative of Cy3 (HY-D0822) dye containing sulfonate ions. Sulfo Cy3 bis COOH contains carboxyl groups, which can condense ammonia to form covalent bonds.
|
-
- HY-D2486
-
|
|
Fluorescent Dye
|
|
Sulfo Cy3 bis NHS ester is a derivative of Cy3 (HY-D0822) dye containing sulfonate ions. Sulfo Cy3 bis NHS ester can be used to label the primary amines (R-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.
|
-
- HY-D3233
-
|
|
Fluorescent Dye
|
|
Ctrl-BDPS1 is a BODIPY-based control probe that shows no response to copper ions (exhibiting two emission peaks at 575 nm and 708 nm; the maximum excitation wavelength is at 627 nm). Ctrl-BDPS1 has no fluorescent response to Cu + .
|
| Cat. No. |
Product Name |
Type |
-
- HY-Y0006
-
|
2-(Dicyclohexylphosphino)-2',4',6'-triisopropylbiphenyl
|
Biochemical Assay Reagents
|
|
XPhos is a dual aryl monophosphine ligand. XPhos is an efficient and stable palladium catalytic ligand. XPhos can be used for amination of aryl sulfonate esters .
|
-
- HY-W099535
-
|
|
Biochemical Assay Reagents
|
|
Lithium dodecyl sulfate is an anionic hydrocarbon surfactant with both surface tension reduction and interfacial adsorption capabilities. Lithium dodecyl sulfate induces low surface viscosity; it forms micelles in aqueous solutions through entropy-driven (low temperature) and enthalpy-driven (high temperature) mechanisms. When acting synergistically with tetrabutylammonium bromide, Lithium dodecyl sulfate exhibits cloud point behavior due to micelle aggregation and phase separation. Lithium dodecyl sulfate can form an adsorption layer at the air-water interface with quantifiable surface excess and minimum area per molecule, and it has higher equilibrium surface tension and foamability compared to other dodecyl sulfate counterion variants. The foam stability of Lithium dodecyl sulfate above its critical micelle concentration is low, and its dynamic surface tension pattern changes dynamically with bubble frequency .
|
-
- HY-W014837
-
|
3-(1-Pyridinio)-1-propanesulfonate
|
Biochemical Assay Reagents
|
|
NDSB-201 consists of a pyridine group attached to a propane chain, which in turn is attached to a sulfonate group. This compound is commonly used as a buffer in biochemical and biological research, especially in electrophoretic applications. It maintains a stable pH in aqueous solutions and has low UV absorption, making it suitable for use in the UV spectrum. Furthermore, due to its ability to form stable complexes with DNA and other biomolecules, 3-(pyridin-1-ium-1-yl)propane-1-sulfonate has been investigated for its potential in drug delivery and genetic research.
|
-
- HY-W099581
-
|
SB3-14; DMAPS
|
Biochemical Assay Reagents
|
|
Zwittergent 3-14 (DMAPS) is a zwitterionic detergent commonly used in biochemistry and molecular biology for the solubilization and purification of membrane-bound proteins and other hydrophobic biomolecules, which have both hydrophilic and hydrophobic moieties , so that it has good detergency properties, making it suitable for stabilizing membrane proteins in aqueous solutions. In addition, DMAPS has been used in various techniques such as electrophoresis and chromatography for the separation and analysis of biomolecules. The long The hydrocarbon chains provide it with good membrane penetration and solubilization capabilities, while the sulfonate and quaternary ammonium groups ensure water solubility and charge neutrality.
|
-
- HY-B0812
-
|
SSA dihydrate
|
Biochemical Assay Reagents
|
|
5-Sulfosalicylic acid dihydrate is a sulfonated salicylic acid derivative. 5-Sulfosalicylic acid dihydrate is effective against the breast cancer cell line, MCF-7, with less toxicity . 5-Sulfosalicylic acid dihydrate has antioxidant activities .
|
-
- HY-W250727
-
|
6-(p-Tolylamino)naphthalene-2-sulfonate sodium
|
Biochemical Assay Reagents
|
|
TNS (6-(p-Tolylamino) naphthalene-2-sulfonate) sodium is a fluorescent probe used to detect the conformational state of proteins. TNS sodium binds to the central hydrophobic calyx of β-lactoglobulin (β-LG) to form a 1:1 complex, which stabilizes the folded conformation of β-LG. TNS sodium shows weak fluorescent signals in aqueous solution, but its fluorescence intensity increases significantly upon binding to the hydrophobic domains of proteins, with the maximum excitation wavelength and maximum emission wavelength located at 321 nm and 446 nm, respectively .
|
-
- HY-W250153
-
|
|
Biochemical Assay Reagents
|
|
Adenosine 3'-phosphate 5'-phosphosulfate lithium, an adenine nucleotide derivative, is a selective P2Y1 antagonist with no effect on P2Y2, P2Y4, or P2Y6 receptors. Adenosine 3'-phosphate 5'-phosphosulfate lithium can competitive inhibit ADP-induced platelet aggregation, as well as the ability of ADP to cause shape change and increases in Ca 2+ in platelets, but had no effect on the inhibition of stimulated adenylate cyclase by ADP. Adenosine 3'-phosphate 5'-phosphosulfate lithium is a co-substrate used for the sulfonation of glycans. Adenosine 3'-phosphate 5'-phosphosulfate lithium can be used for Golgi-resident PAP-specific 3'-phosphatase-coupled sulfotransferase assays, which as donor substrate to transfer a sulfonate group .
|
-
- HY-W014792
-
|
|
Biochemical Assay Reagents
|
|
Sodium heptane-1-sulfonate is an ion-pairing agent that can be used as a buffer in biochemical research and HPLC .
|
-
- HY-W099575
-
|
|
Biochemical Assay Reagents
|
|
3-(Hexadecyldimethylammonio)propane-1-sulfonate is an organic compound belonging to the class of sulfonates. It is a quaternary ammonium surfactant commonly used in various industrial and laboratory applications such as the production of detergents, personal care products and pharmaceuticals. 3-(Hexadecyldimethylammonio)propane-1-sulfonate is surface active and can be used as an emulsifier, foaming agent and wetting agent. In addition, it is used as a solubilizer in protein purification and as a surfactant in chromatography.
|
-
- HY-W008600
-
|
|
Biochemical Assay Reagents
|
|
Sodium octane-1-sulfonate is an ion-pairing agent that can be used as a buffer in biochemical research and HPLC .
|
-
- HY-W016091
-
|
|
Biochemical Assay Reagents
|
|
Sodium heptane-1-sulfonate is an ion-pairing agent that can be used as a buffer in biochemical research and HPLC .
|
-
- HY-W099581R
-
|
SB3-14 (Standard); DMAPS (Standard)
|
Biochemical Assay Reagents
|
|
Sulfobetaine-14 (Standard) is the analytical standard of Sulfobetaine-14. This product is intended for research and analytical applications. Zwittergent 3-14 (DMAPS) is a zwitterionic detergent commonly used in biochemistry and molecular biology for the solubilization and purification of membrane-bound proteins and other hydrophobic biomolecules, which have both hydrophilic and hydrophobic moieties , so that it has good detergency properties, making it suitable for stabilizing membrane proteins in aqueous solutions. In addition, DMAPS has been used in various techniques such as electrophoresis and chromatography for the separation and analysis of biomolecules. The long The hydrocarbon chains provide it with good membrane penetration and solubilization capabilities, while the sulfonate and quaternary ammonium groups ensure water solubility and charge neutrality.
|
-
- HY-W017224
-
|
Sodium 1-butanesulfonate
|
Biochemical Assay Reagents
|
|
Sodium butane-1-sulfonate (Sodium 1-butanesulfonate) is an ion-pair reagent. Sodium butane-1-sulfonate is often used in combination with tetramethylammonium hydroxide, malonic acid, etc. in reversed-phase ion-pair chromatography, and can improve the separation efficiency of species of elements such as arsenic and selenium .
|
-
- HY-101410A
-
|
Symmetric dimethylarginine (p-hydroxyazobenzene-p′-sulfonate); NG,NG'-Dimethyl-L-arginine (p-hydroxyazobenzene-p′-sulfonate)
|
Biochemical Assay Reagents
|
|
SDMA p-hydroxyazobenzene-p′-sulfonate is the p-hydroxyazobenzene-p′-sulfonate salt form of SDMA (HY-101410). SDMA p-hydroxyazobenzene-p′-sulfonate is an endogenous inhibitor of nitric oxide synthase (NO synthase) activity. SDMA p-hydroxyazobenzene-p′-sulfonate is an activator for NF-κB, and promotes the expression of IL-6 and TNF-α. SDMA p-hydroxyazobenzene-p′-sulfonate is stable in serum and plasma, and can be used as a kidney biomarker of hepatic and renal dysfunction .
|
-
- HY-W009545
-
|
1-Decanesulfonic acid sodium
|
Biochemical Assay Reagents
|
|
Sodium decane-1-sulfonate is an anionic surfactant used for the analysis of organic small molecule compounds by HPLC and ion-pair liquid chromatography.
|
-
- HY-W087892
-
|
|
Biochemical Assay Reagents
|
|
Barium diphenylamine-4-sulfonate can be employed as an intermediate in pharmaceutical manufacturing and in chemical research, and serves as a dosing agent in analytical testing .
|
-
- HY-W016791
-
|
Sodium pentane-1-sulfonate, 98%; NaPS, 98%
|
Biochemical Assay Reagents
|
|
Sodium pentanesulfonate, 98% (Sodium pentane-1-sulfonate, 98%; NaPS, 98%) is an anionic surfactant that can promote the solubility of proteins and membrane proteins. Sodium pentanesulfonate, 98% is a kind of biological materials or organic compounds that are widely used in life science research .
|
-
- HY-W250153A
-
|
|
Biochemical Assay Reagents
|
|
Adenosine 3'-phosphate 5'-phosphosulfate lithium hydrate, an adenine nucleotide derivative, is a selective P2Y1 antagonist with no effect on P2Y2, P2Y4, or P2Y6 receptors. Adenosine 3'-phosphate 5'-phosphosulfate lithium hydrate can competitive inhibit ADP-induced platelet aggregation, as well as the ability of ADP to cause shape change and increases in Ca 2+ in platelets, but had no effect on the inhibition of stimulated adenylate cyclase by ADP. Adenosine 3'-phosphate 5'-phosphosulfate lithium hydrate is a co-substrate used for the sulfonation of glycans. Adenosine 3'-phosphate 5'-phosphosulfate lithium hydrate can be used for Golgi-resident PAP-specific 3'-phosphatase-coupled sulfotransferase assays, which as donor substrate to transfer a sulfonate group .
|
-
- HY-W115743
-
|
|
Biochemical Assay Reagents
|
|
Sulfonated castor oil is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W008600R
-
|
|
Biochemical Assay Reagents
|
|
Sodium octane-1-sulfonate (Standard) is the analytical standard of Sodium octane-1-sulfonate. This product is intended for research and analytical applications. Sodium octane-1-sulfonate is an ion-pairing agent that can be used as a buffer in biochemical research and HPLC .
|
-
- HY-W009545R
-
|
1-Decanesulfonic acid sodium (Standard)
|
Biochemical Assay Reagents
|
|
Sodium decane-1-sulfonate (Standard) is the analytical standard of Sodium decane-1-sulfonate. This product is intended for research and analytical applications. Sodium decane-1-sulfonate is an anionic surfactant used for the analysis of organic small molecule compounds by HPLC and ion-pair liquid chromatography.
|
-
- HY-W008974
-
|
|
Biochemical Assay Reagents
|
|
3-(Dimethyl(octadecyl)ammonio)propane-1-sulfonate is a class of quaternary ammonium compounds. It is a surfactant and cationic detergent with amphiphilic properties and therefore useful in various industrial and biomedical applications. 3-(Dimethyl(octadecyl)ammonium)propane-1-sulfonate is commonly used as an emulsifier, solubilizer and antimicrobial agent in personal care products, detergents, textiles and pharmaceutical formulations. It is also used as a reagent in analytical chemistry, especially in the analysis of proteins and DNA.
|
-
- HY-142987
-
-
- HY-NP186
-
|
|
Biochemical Assay Reagents
|
|
Helix pomatia Agglutinin is a N-acetylgalactosamine (GalNAc) binding lectin, found in the reproductive gland of a Roman snail. Helix pomatia Agglutinin binds with high affinity (kD = 1.9-2.4 μM) steroid hormones: testosterone and progesterone. Helix pomatia Agglutinin interacts with adenine (kD = 5.4 μM) and arylaminonaphthalene sulfonate TNS (kD = 12 μM). Helix pomatia Agglutinin is commonly used for characterizing, imaging, or targeting glycoconjugates, and is also a very useful tool for glycomics analysis . Helix pomatia Agglutinin can be used for cancer prognosis study .
|
-
- HY-W087892R
-
|
|
Biochemical Assay Reagents
|
|
Barium diphenylamine-4-sulfonate (Standard) is the analytical standard of Barium diphenylamine-4-sulfonate. This product is intended for research and analytical applications. Barium diphenylamine-4-sulfonate can be employed as an intermediate in pharmaceutical manufacturing and in chemical research, and serves as a dosing agent in analytical testing .
|
| Cat. No. |
Product Name |
Target |
Research Area |
-
- HY-P5834A
-
|
|
Caspase
Apoptosis
|
Inflammation/Immunology
|
|
Boc-AEVD-CHO TFA is a Caspase 8 inhibitor. Boc-AEVD-CHO TFA significantly increases the frequencies of Nocodazole (HY-13520) or methyl methane sulfonate (MMS) induced micronuclei (MN) and micronucleated binucleates (MNCB) in PBMC by inhibiting cell apoptosis. Boc-AEVD-CHO TFA can be used for immune and inflammatory diseases research .
|
| Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
| Cat. No. |
Product Name |
Chemical Structure |
-
- HY-W102347S
-
|
|
|
Sodium 2-(acetylthio)ethane-1-sulfonate-1,1,2,2-d4 is the deuterium labeled Sodium 2-(acetylthio)ethanesulfonate (HY-W102347).
|
-
-
- HY-W714694
-
|
|
|
Metolachlor ESA Sodium Salt-d6 is the deuterium labeled Sodium 2-((2-ethyl-6-methylphenyl)(1-methoxypropan-2-yl)amino)-2-oxoethane-1-sulfonate (HY-W714198).
|
-
-
- HY-W755726
-
|
|
|
Sodium 2-((4-fluorophenyl)(isopropyl)amino)-2-oxoethane-1-sulfonate-d7 is deuterium labeled Sodium 2-((4-fluorophenyl)(isopropyl)amino)-2-oxoethane-1-sulfonate .
|
-
-
- HY-W714703S
-
|
|
|
Sodium 2-((2,6-dimethylphenyl)(2-(methoxy-d3)ethyl)amino)-2-oxoethane-1-sulfonate is deuterium labeled Sodium 2-((2,6-dimethylphenyl)(2-methoxyethyl)amino)-2-oxoethane-1-sulfonate .
|
-
-
- HY-165704S
-
|
|
|
2-(3-Carbamoyl-1-((6-chloropyridin-3-yl)methyl)ureido)ethane-1-sulfonate (sodium)-d4 is deuterium labeled 2-(3-Carbamoyl-1-((6-chloropyridin-3-yl)methyl)ureido)ethane-1-sulfonate (sodium) .
|
-
-
- HY-165693S
-
|
|
|
Sodium 2-((2,6-bis(methyl-d3)phenyl-3,4,5-d3)amino)-2-oxoethane-1-sulfonate is deuterium labeled Sodium 2-((2,6-dimethylphenyl)amino)-2-oxoethane-1-sulfonate .
|
-
-
- HY-W714705S
-
|
|
|
(S)-Metolachlor metabolite CGA 368208-d3 sodium salt (Sodium 2-((2-(ethyl-2,2,2-d3)-6-methylphenyl)amino)-2-oxoethane-1-sulfonate) is deuterium labeled Sodium 2-((2-ethyl-6-methylphenyl)amino)-2-oxoethane-1-sulfonate .
|
-
-
- HY-W714698
-
|
|
|
Dimethachlor ethane sulfonic acid sodium salt-d6 is the deuterium labeled Sodium 2-((2,6-dimethylphenyl)(2-methoxyethyl)amino)-2-oxoethane-1-sulfonate (HY-W714703).
|
-
-
- HY-W726709
-
|
|
|
Propachlor ESA-d5 (2-[(1-Methylethyl)phenylamino-d5]-2-oxoethanesulfonic acid) sodiumis deuterium labeled Sodium 2-(isopropyl(phenyl)amino)-2-oxoethane-1-sulfonate .
|
-
| Cat. No. |
Product Name |
|
Classification |
-
- HY-151759
-
|
|
|
Labeling and Fluorescence Imaging
TCO
|
|
Sulfo-Cy5-TCO is a water-soluble sulfonated Cy5 fluorescent reagent containing trans-cyclooctene (TCO). Sulfo-Cy5-TCO undergoes an inverse electron demand Diels‑Alder reaction with tetrazine-labeled fixed breast cancer cells to achieve cell labeling. Sulfo-Cy5-TCO is used for fluorescent labeling and imaging of biological samples such as proteins and cells .
|
-
- HY-D2750
-
|
|
|
Azide
|
|
Sulfo-Cy5 Picolyl Azide is a fluorophore featuring a sulfonate group and an azide. Azide groups are click chemistry handles which are reactive towards terminal alkynes and strained cyclooctynes such as BCN or DBCO. Cy5 is a cyanine dye with excitation and emission maxima at 651 nm and 670 nm respectively. The sulfonate group on the Cy5 dye increases this compound’s water solubility.
|
-
- HY-D2242
-
|
|
|
DBCO
|
|
Sulfo-Cy7.5 DBCO is a dye derivative of Cyanine 7.5 (Cy7.5) (HY-D0926) bearing a DBCO group. The sulfonate ion increases the water solubility of the compound, making it suitable for use in aqueous solutions. Sulfo-Cy7.5 DBCO can bind to biomolecules such as proteins and antibodies to track their location and dynamic changes in biological samples .
|
-
- HY-D1860
-
|
|
|
Alkynes
|
|
Cy3 alkyne chloride is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing a sulfonate ion and an alkyne functional group. Cy3 is a fluorescent dye with a fluorescence spectrum typically in the green to orange wavelength range. The alkyne functional group of Cy3 alkyne chloride can react with molecules containing the azide functional group to form covalent bonds. Cy3 alkyne chloride can bind to biological molecules such as proteins and antibodies to track their location and dynamic changes in biological samples.
|
-
- HY-D1307A
-
|
|
|
Alkynes
|
|
Sulfo-cyanine7 alkyne potassium is a water-soluble near-infrared dye with a sulfonated terminal alkyne that can be used in copper-catalyzed click chemistry reactions to conjugate with azides in an aqueous environment.
|
-
- HY-D1307
-
|
|
|
Alkynes
|
|
Sulfo-cyanine7 alkyne is a water-soluble near-infrared dye with a sulfonated terminal alkyne that can be used in copper-catalyzed click chemistry reactions to conjugate with azides in an aqueous environment.
|
-
- HY-D1859
-
|
|
|
Alkynes
|
|
Sulfo-Cy7.5 alkyne is a dye derivative of Cyanine 7.5 (Cy7.5) (HY-D0926) containing a sulfonate ion and an alkyne functional group. The sulfonate ion increases the water solubility of the compound, making it suitable for use in aqueous solutions. Cy7.5 is a near-infrared fluorescent dye commonly used for biolabeling and cell imaging. The alkyne functionality of Sulfo-Cy7.5 alkyne can react with molecules containing the azide functionality to form covalent bonds. Sulfo-Cy7.5 alkyne can bind to biomolecules such as proteins and antibodies to track their location and dynamic changes in biological samples.
|
-
- HY-D1850
-
|
|
|
Azide
|
|
Sulfo-Cy7.5 azide is a Cyanine 7.5 (Cy7.5) (HY-D0926) dye derivative with azide and sulfonate functional groups. The sulfonate ion increases the water solubility of the compound, making it suitable for use in aqueous solutions. Cy7.5 is a near-infrared fluorescent dye commonly used for biolabeling and cell imaging. The azide group of Sulfo-Cy7.5 azide can react chemically with molecules containing alkyne functionality, such as alkyne or cyclooctyne, to form covalent bonds. Therefore, Sulfo-Cy7.5 azide can bind to biomolecules such as proteins and antibodies to track their location and dynamic changes in biological samples. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
|
-
- HY-D2759
-
|
|
|
Azide
|
|
Cyanine3B azide for click chemistry conjugation with terminal alkynes via a copper-catalyzed click reaction or strained cyclooctynes via a copper-free click reaction.
Cyanine3B is a yellow-emitting cyanine dye that is an improved version of the Cyanine3 fluorophore with significantly higher fluorescence quantum yield and photostability. Due to the fixed conformation, Cyanine3B has the highest emission quantum yield compared to other dyes of this wavelength.
This is a non-sulfonated dye that requires an organic co-solvent (DMF, DMSO, or other) for efficient labeling in water.
|
-
- HY-D1862
-
|
|
|
Alkynes
|
|
Cy7.5 alkyne chloride is a dye derivative of Cyanine 7.5 (Cy7.5) (HY-D0926) containing a sulfonate ion and an alkyne functional group. Cy7.5 is a near-infrared fluorescent dye commonly used for biolabeling and cell imaging. The alkyne functional group of Cy7.5 alkyne chloride can react with molecules containing the azide functional group to form covalent bonds. Cy7.5 alkyne chloride can bind to biological molecules such as proteins and antibodies to track their location and dynamic changes in biological samples.
|
| Cat. No. |
Product Name |
|
Classification |
-
- HY-W250153
-
|
|
|
Nucleotide Analogs
Adenine Nucleotide
|
|
Adenosine 3'-phosphate 5'-phosphosulfate lithium, an adenine nucleotide derivative, is a selective P2Y1 antagonist with no effect on P2Y2, P2Y4, or P2Y6 receptors. Adenosine 3'-phosphate 5'-phosphosulfate lithium can competitive inhibit ADP-induced platelet aggregation, as well as the ability of ADP to cause shape change and increases in Ca 2+ in platelets, but had no effect on the inhibition of stimulated adenylate cyclase by ADP. Adenosine 3'-phosphate 5'-phosphosulfate lithium is a co-substrate used for the sulfonation of glycans. Adenosine 3'-phosphate 5'-phosphosulfate lithium can be used for Golgi-resident PAP-specific 3'-phosphatase-coupled sulfotransferase assays, which as donor substrate to transfer a sulfonate group .
|
-
- HY-164090
-
|
|
|
Nucleotide Analogs
Adenine Nucleotide
|
|
Adenosine 3'-phosphate 5'-phosphosulfate, an adenine nucleotide derivative, is a selective P2Y1 antagonist with no effect on P2Y2, P2Y4, or P2Y6 receptors. Adenosine 3'-phosphate 5'-phosphosulfate can competitive inhibit ADP-induced platelet aggregation, as well as the ability of ADP to cause shape change and increases in Ca 2+ in platelets, but had no effect on the inhibition of stimulated adenylate cyclase by ADP. Adenosine 3'-phosphate 5'-phosphosulfate is a co-substrate used for the sulfonation of glycans. Adenosine 3'-phosphate 5'-phosphosulfate can be used for Golgi-resident PAP-specific 3'-phosphatase-coupled sulfotransferase assays, which as donor substrate to transfer a sulfonate group .
|
-
- HY-W250153A
-
|
|
|
Nucleotide Analogs
Adenine Nucleotide
|
|
Adenosine 3'-phosphate 5'-phosphosulfate lithium hydrate, an adenine nucleotide derivative, is a selective P2Y1 antagonist with no effect on P2Y2, P2Y4, or P2Y6 receptors. Adenosine 3'-phosphate 5'-phosphosulfate lithium hydrate can competitive inhibit ADP-induced platelet aggregation, as well as the ability of ADP to cause shape change and increases in Ca 2+ in platelets, but had no effect on the inhibition of stimulated adenylate cyclase by ADP. Adenosine 3'-phosphate 5'-phosphosulfate lithium hydrate is a co-substrate used for the sulfonation of glycans. Adenosine 3'-phosphate 5'-phosphosulfate lithium hydrate can be used for Golgi-resident PAP-specific 3'-phosphatase-coupled sulfotransferase assays, which as donor substrate to transfer a sulfonate group .
|
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