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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
255 Results for "
thiol groups
" in MedChemExpress (MCE) Product Catalog:
Products (255)
255 Results for "thiol groups" in MCE Product Catalog:
18
4
4 Cited Publications
Art. -Nr.: HY-166648A
DSPE-PEG-Maleimide ammonium (MW 2000) is a functional lipid component and a thiol-reactive crosslinker. DSPE-PEG-Maleimide ammonium (MW 2000) undergoes Michael addition with the thiol groups of thiolated or cyclic RGD peptides to form stable thioether bonds and DSPE-PEG (2000)-RGD. DSPE-PEG-Maleimide ammonium (MW 2000) is applicable to research on drug delivery .
4
4 Cited Publications
Art. -Nr.: HY-166648
DSPE-PEG2000-Maleimide sodium (purity>98%) is a functional lipid component and a thiol-reactive crosslinker. DSPE-PEG2000-Maleimide sodium (purity>98%) undergoes Michael addition with the thiol groups of thiolated or cyclic RGD peptides to form stable thioether bonds and DSPE-PEG2000-RGD. DSPE-PEG2000-Maleimide sodium (purity>98%) is applicable to research on drug delivery .
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3 Cited Publications
Target:
Forschungsgebiete:
N-Acetyl-D-cysteine has antioxidant activities and scavenges ROS through the reaction with its thiol group, but cannot enter the glutathione metabolic pathway .
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2
2 Cited Publications
Target:
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Biotin-BMCC is a Maliemide (HY-W007324) conjugated biotin molecule that has a high affinity for free thiol groups of cysteines .
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Sodium 2-mercaptoethanesulfonate (Mesnum) is a thiol-containing urinary tract protective agent and aldehyde scavenger that detoxifies acrolein via its thiol group to form an inert thioether excreted in urine, and competitively inhibits human myeloperoxidase, thereby mitigating Cyclophosphamide (HY-17420)-induced cytogenetic damage. Sodium 2-mercaptoethanesulfonate can be used for research on hemorrhagic cystitis .
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Dichlorophen is a chlorophenol antimicrobial agent that can destroy the integrity of microbial cell membranes and interfere with the activity of metabolic enzymes. Dichlorophen can covalently bind to the thiol groups of microbial proteins and has broad-spectrum antibacterial, antifungal and anthelmintic activity. Dichlorophen can be used as an antimicrobial agent in the study of drug-resistant bacterial infections .
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2
2 Cited Publications
Art. -Nr.: HY-15941
CAS. Nr.: 27072-45-3
Synonyms: Fluorescein 5(6)-isothiocyanate; Fluorescein isothiocyanate 5- and 6- isomers
1
1 Cited Publications
Art. -Nr.: HY-D1423
CAS. Nr.: 68654-25-1
Target:
Forschungsgebiete:
Dibromobimane is a Fluorescent dye and probe that can be used for the detection of intracellular reduced glutathione and the analysis of spatial proximity of closely adjacent cysteine thiol groups. Dibromobimane activates fluorescence through binding to thiol groups; its excitation/emission wavelengths are Ex/Em = 393/477 nm for glutathione detection, and Ex/Em = 385/477 nm for cysteine thiol cross-linking. Dibromobimane uses two equivalent bromomethyl groups to cross-link cysteine thiolates with a distance ranging from 3-6 Å. Dibromobimane can be applied to 96-well microplate-based high-throughput assays for labeling intracellular glutathione, and its fluorescence signal is normalized against nuclear staining results to eliminate the impact of cell density .
1
1 Cited Publications
Synonyms: Cyanine5 maleimide
1
1 Cited Publications
Art. -Nr.: HY-W1048553B
Art. -Nr.: HY-W591476
CAS. Nr.: 134874-49-0
Synonyms: mPEG1000-SH
Art. -Nr.: HY-140651
Reinheit: ≥93.0%
Target:
Forschungsgebiete:
Amine-PEG2000-thiol is a conjugate containing amino, PEG and thiol groups, used for drug delivery, material modification and chemical synthesis.
Art. -Nr.: HY-138525
CAS. Nr.: 2720615-82-5
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Forschungsgebiete:
Azido-PEG4-Thiol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG4-Thiol is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Art. -Nr.: HY-W998680
CAS. Nr.: 2228857-33-6
Synonyms: 5-FITC-Maleimide
Art. -Nr.: HY-W441004
CAS. Nr.: 144735-82-0
Target:
Forschungsgebiete:
DSPE-Thiol is a modified phospholipid containing a reactive thiol group (-SH), featuring two saturated stearoyl chains, and used mainly for liposome and nanoparticle bioconjugation. DSPE-Thiol helps attach targeting ligands, stabilize membranes, and form covalent bonds .
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Poly (ethylene glycol) dithiol (Mn 3400) is a bifunctional thiol-terminated PEG crosslinking and polymerization reagent. The terminal thiol groups of Poly (ethylene glycol) dithiol (Mn 3400) can undergo thiol-ene photochemical click reactions with norbornene groups, thereby crosslinking to form hydrogel networks; it can also serve as a dithiol monomer in the step-growth polymerization of hexahydrotriazine (HT) to form poly (thioaminal) polymers containing dynamic thioacetal bonds. Poly (ethylene glycol) dithiol (Mn 3400) is applicable for hydrogel construction, biomanufacturing, and dynamic covalent polymer research .
Art. -Nr.: HY-W1048549A
Synonyms: HOOC-PEG2000-thiol
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
