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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
117 Results for "
transforming growth factor-β
" in MedChemExpress (MCE) Product Catalog:
Products (117)
117 Results for "transforming growth factor-β" in MCE Product Catalog:
23
23 Publications Verification
Synonyms: E-616452; SJN 2511
Target:
Research Areas:
RepSox (E-616452) is a potent and selective transforming growth factor-beta receptor I/activin like kinase 5 (TGF-β-RI/ALK5) inhibitor. RepSox inhibits ALK5 autophosphorylation with an IC50 value of 4 nM. RepSox can be used for the research of obesity and associated metabolic diseases such as type 2 diabetes .
19
Target:
Research Areas:
19
Target:
Research Areas:
13
13 Cited Publications
Cat. No.: HY-P7119
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TGFB2; transforming growth factor, Beta 2; transforming growth factor Beta 2; BSC-1 Cell growth Inhibitor; Glioblastoma-Derived T-Cell Suppressor factor; TGF-Beta2; transforming growth factor Beta-2 Proprotein; Polyergin; Prepro-transforming growth factor
Species:
Human
Source:
HEK293
10
10 Cited Publications
Cat. No.: HY-P7120
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TGFB3; transforming growth factor, Beta 3; Prev. ARVD1; transforming growth factor Beta; Prev. ARVD; TGF-Beta3; transforming growth factor Beta-3 Proprotein; LDS5; Prepro-transforming growth factor Beta-3; RNHF; Arrhythmogenic Right Ventricular Dysplasia
Species:
Human
Source:
HEK293
5
Target:
Research Areas:
Luspatercept (ACE-536) is a recombinant modified ActRIIB fusion protein that binds with transforming growth factor β superfamily ligands. Luspatercept increases the erythrocyte numbers and promotes maturation of erythroid precursors. Luspatercept binds with GDF11 and inhibits Smad2/3 signaling. Luspatercept can be used for the research of anemia .
3
3 Cited Publications
Target:
Research Areas:
SJ000291942 is an activator of the canonical bone morphogenetic proteins (BMP) signaling pathway. BMPs are members of the transforming growth factor beta (TGFβ) family of secreted signaling molecules.
3
3 Cited Publications
Synonyms: Antibiotic A 15104 Y; PClP
Target:
Research Areas:
Pentachloropseudilin (Antibiotic A 15104 Y; PClP) is a reversible and allosteric potent inhibitor of Myo1s (class 1 myosins) with IC50s range from 1 to 5 μM for mammalian class-1 myosins and greater than 90 μM for class-2 and class-5 myosins. Pentachloropseudilin is a potent inhibitor of transforming growth factor-β (TGF-β)-stimulated signaling, with an IC50 of 0.1 to 0.2 μM for TGF-β .
3
3 Cited Publications
Cat. No.: HY-P78213
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: TGFB1; transforming growth factor Beta1; Prev. TGFB; Camurati-Engelmann Disease; Prev. DPD1; Latency-Associated Peptide; TGFbeta; TGF-Beta-1; CED; TGF-Beta1; transforming growth factor Beta-1 Proprotein; IBDIMDE; Prepro-transforming growth factor Beta-1; CAEND1; transforming growth factor, Beta 1; LAP; Diaphyseal Dysplasia 1, Progressive; transforming growth factor Beta 1; transforming growth factor Beta
Species:
Human
Source:
HEK293
2
2 Cited Publications
Cat. No.: HY-18758
CAS No.: 868612-83-3
Target:
Research Areas:
IN-1130 is a highly selective transforming growth factor-β type I receptor kinase (ALK5) inhibitor with an IC50 of 5.3 nM for ALK5-mediated Smad3 phosphorylation. IN-1130 inhibits ALK5 phosphorylation of casein (IC50=36 nM) and p38α mitogen-activated protein kinase (IC50=4.3 μM). IN-1130 suppresses renal fibrosis in obstructive nephropathy and blocks breast cancer lung metastasis .
2
2 Cited Publications
Cat. No.: HY-P700785
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: TGFB2; transforming growth factor, Beta 2; transforming growth factor Beta 2; BSC-1 Cell growth Inhibitor; Glioblastoma-Derived T-Cell Suppressor factor; TGF-Beta2; transforming growth factor Beta-2 Proprotein; Polyergin; Prepro-transforming growth factor
Species:
Human
Source:
HEK293
2
2 Cited Publications
Cat. No.: HY-P70649
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TGFB2; transforming growth factor, Beta 2; transforming growth factor Beta 2; BSC-1 Cell growth Inhibitor; Glioblastoma-Derived T-Cell Suppressor factor; TGF-Beta2; transforming growth factor Beta-2 Proprotein; Polyergin; Prepro-transforming growth factor Beta-2; CAEND2; Cetermin; LDS4; G-TSF
Species:
Rat
Mouse
Source:
HEK293
2
2 Cited Publications
Cat. No.: HY-P72454
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TGFBR1; Serine/Threonine-Protein Kinase Receptor R4; Prev. ESS1; Activin Receptor-Like Kinase 5; Prev. MSSE; TbetaR-I; ALK-5; TGFR-1; ALK5; SKR4; transforming growth factor-Beta Receptor Type I; Multiple Self-Healing Squamous Epithelioma; TGF-Beta Recepto
Species:
Mouse
Source:
HEK293
1
1 Cited Publications
Target:
Research Areas:
TGFβ-IN-5 is a type I transforming growth factor-β receptor (TGF-β R1) kinase inhibitor with an IC50 value of 0.0485 μM. TGFβ-IN-5 reverses the effect of TGF-β-mediated cell activation on the expression of fibrosis-related genes. TGFβ-IN-5 can be used in the research of fibroproliferative diseases .
1
1 Cited Publications
Target:
1
1 Cited Publications
Cat. No.: HY-P78524
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: TGFBR2; transforming growth factor, Beta Receptor II Gamma; Prev. MFS2; transforming growth factor, Beta Receptor II Beta; TGF-Beta Type II Receptor; Serine/Threonine-Protein Kinase Receptor; TGF-Beta Receptor Type-2; Receptor Protein Serine/Threonine Kinase; TBR-Ii; TGF-Beta Receptor Type IIB; TGFR-2; TGF-Beta Receptor Type II; TBRII; TGFbeta-RII; transforming growth factor, Beta Receptor II (70/80kDa); LDS1B; transforming growth factor-Beta Receptor Type II; LDS2B; transforming growth factor Beta Receptor II; TAAD2; TbetaR-II; AAT3; transforming growth factor, Beta Receptor II Epsilon; FAA3; transforming growth factor, Beta Receptor II Alpha; LDS2; transforming growth factor, Beta Receptor II Delta; RIIC; transforming growth factor Beta Receptor 2; transforming growth factor Beta Receptor Type IIC
Species:
Human
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-P700152AF
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TGFB3; transforming growth factor, Beta 3; Prev. ARVD1; transforming growth factor Beta; Prev. ARVD; TGF-Beta3; transforming growth factor Beta-3 Proprotein; LDS5; Prepro-transforming growth factor Beta-3; RNHF; Arrhythmogenic Right Ventricular Dysplasia
Species:
Human
Source:
E. coli
1
1 Cited Publications
Cat. No.: HY-P74525A
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: TGFBI; RGD-Containing Collagen-Associated Protein; Prev. CSD1; Beta Ig-H3; Prev. CSD2; RGD-CAP; Prev. CSD3; transforming growth factor, Beta-Induced, 68kDa; Prev. LCD1; transforming growth factor Beta-Induced 68kDa; BIGH3; transforming growth factor Beta
Species:
Human
Source:
HEK293
1
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
