18 Results for "

v-src

" in MedChemExpress (MCE) Product Catalog:
Products (18)

18 Results for "v-src" in MCE Product Catalog:

7
7 Publications Verification
Cat. No.: HY-13942
CAS No.: 221244-14-0
Purity:  99.17%
Synonyms: PP1 Analog II
Target:  

Src

Research Areas:  

Cancer

1-NM-PP1, a cell-permeable PP1 analog, is a potent Src family kinases inhibitor with IC50s of 4.3 nM and 3.2 nM for v-Src-as1 and c-Fyn-as1, respectively .
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3
3 Cited Publications
Cat. No.: HY-13941
CAS No.: 221243-82-9
Purity:  98.96%
Synonyms: 1-NA-PP 1
Target:  

Src PKD

1-Naphthyl PP1 (1-NA-PP 1) is a selective inhibitor of src family kinases and Protein Kinase D. 1-Naphthyl PP1 inhibits v-Src and c-Fyn, c-Abl, CDK2 and CAMK II with IC50s of 1.0, 0.6, 0.6, 18 and 22 μM, respectively .
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3
3 Cited Publications
Cat. No.: HY-13941B
CAS No.: 956025-47-1
Purity:  99.83%
Synonyms: 1-NA-PP 1 hydrochloride
Target:  

Src PKD

1-Naphthyl PP1 hydrochloride (1-NA-PP 1 hydrochloride) is a selective inhibitor of src family kinases and Protein Kinase D. 1-Naphthyl PP1 hydrochloride inhibits v-Src and c-Fyn, c-Abl, CDK2 and CAMK II with IC50s of 1.0, 0.6, 0.6, 18 and 22 μM, respectively .
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1
1 Cited Publications
Cat. No.: HY-P701321
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: src; Tyrosine Kinase Pp60c-src; Prev. src1; P60-src; C-src; Protooncogene src, Rous Sarcoma; ASV; Tyrosine-Protein Kinase src-1; V-src Avian Sarcoma (Schmidt-Ruppin A-2) Viral Oncogene Homolog; Pp60c-src; Proto-Oncogene Tyrosine-Protein Kinase src; THC6; src Proto-Oncogene, Non-Receptor Tyrosine Kinase; Proto-Oncogene C-src
Species:  
Human
Source:  
E. coli
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Cat. No.: HY-N4201
CAS No.: 7415-78-3
Beta-hydroxyisovalerylshikonin is a natural product isolated from Lithospermum erythrorhizon, acts as a potent inhibitor of protein tyrosine kinases (PTK), with IC50s of 0.7μM and 1μM for EGFR and v-Src receptor, respectively. Beta-hydroxyisovalerylshikonin is effective against a wide variety of tumor cell lines, and most efficiently induces cell-death in NCI-H522 and DMS114 cells .
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Cat. No.: HY-N7160
CAS No.: 17241-40-6
2-Hydroxy-3-methylanthraquinone (compound 1) is a natural compound isolated from a water extract of Hedyotis diffusa WILLD. 2-Hydroxy-3-methylanthraquinone shows inhibitory activity against protein tyrosine kinases v-src and pp60src, and induces growth arrest and apoptosis in the HepG2 cancer cells .
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Cat. No.: HY-P2548
CAS No.: 176042-83-4
Target:  

EGFR

Research Areas:  

Others

pp60 (v-SRC) Autophosphorylation Site, Phosphorylated is the phosphorylated peptide of an EGFR substrate. pp60 (v-SRC) Autophosphorylation Site, Phosphorylated can be used for the screening of EGFR Kinase inhibitors via phosphorylated-substrate quantification .
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Cat. No.: HY-P3744
CAS No.: 81493-98-3
Target:  

EGFR

Research Areas:  

Others

pp60v-src Autophosphorylation site is a synthetic peptide. pp60v-src Autophosphorylation site can be used for various biochemical studies .
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Cat. No.: HY-P2372
CAS No.: 131023-24-0
Target:  

Src

Research Areas:  

Others

P60v-src(137-157) is a synthetic peptide that inhibits the tyrosine kinase activity of p60 v-src (IC50: 7.5 μM) .
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Cat. No.: HY-16906
CAS No.: 1351927-00-8
Target:  

Src

Research Areas:  

Cancer

T338C Src-IN-2 is a mutant c-Src kinase inhibitor, with an IC50 of 317 nM against T338C c-Src, 57 nM against T338C/V323A c-Src, and 19 nM against T338C/V323S c-Src. T338C Src-IN-2 inhibits the kinase activity of endogenous cysteine gatekeeper MOK. T338C Src-IN-2 reduces global phosphotyrosine levels in v-Src-ES1-transformed NIH-3T3 cells .
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Cat. No.: HY-N14903
CAS No.: 664365-72-4
Oximidine III is an anti-tumor antibiotic. Oximidine III can selectively inhibit the growth of 3Y1 in rat fibroblasts with degeneration of various tumor genes. Oximidine III inhibits v-H-ras-3Y1, v-src-3Y1 cells and the normal 3Y1 cells with IC50s (nM) of 14, 4.5 and 140, respectively. Oximidine III stops RAS-or SRC-denatured cells at G1 phase of the cell cycle and increases p21WAF1 expression .
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Cat. No.: HY-186321
CAS No.: 501124-40-9
Synonyms: KF25706
Target:  

HSP Raf Src CDK MDM-2/p53 Ras

Research Areas:  

Cancer

Radicicol 6-oxime (KF25706) is an Hsp90 inhibitor with an EC50 of 5.5 nM against human Hsp90. Radicicol 6-oxime binds to Hsp90 and disrupts its chaperone function, leading to destabilization and depletion of Hsp90-associated signaling molecules. Radicicol 6-oxime depletes Hsp90-associated signaling proteins such as Raf-1, v-src, p185erbB2, Cdk4, and mutant p53, thereby inhibiting K-ras and v-src signaling pathways. Radicicol 6-oxime exhibits antiproliferative activity against various tumor cells. Radicicol 6-oxime inhibits tumor growth in mouse tumor xenograft models. Radicicol 6-oxime can be used for research on breast cancer, colon cancer, and vulvar epidermoid carcinoma .
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Cat. No.: HY-P705885
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: src; Tyrosine Kinase Pp60c-src; Prev. src1; P60-src; C-src; Protooncogene src, Rous Sarcoma; ASV; Tyrosine-Protein Kinase src-1; V-src Avian Sarcoma (Schmidt-Ruppin A-2) Viral Oncogene Homolog; Pp60c-src; Proto-Oncogene Tyrosine-Protein Kinase src; THC6;
Species:  
Human
Source:  
sf9 insect cells
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Cat. No.: HY-P702724
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: src; Tyrosine Kinase Pp60c-src; Prev. src1; P60-src; C-src; Protooncogene src, Rous Sarcoma; ASV; Tyrosine-Protein Kinase src-1; V-src Avian Sarcoma (Schmidt-Ruppin A-2) Viral Oncogene Homolog; Pp60c-src; Proto-Oncogene Tyrosine-Protein Kinase src; THC6;
Species:  
Human
Source:  
Sf9 insect cells
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Cat. No.: HY-P73423
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: src; Tyrosine Kinase Pp60c-src; Prev. src1; P60-src; C-src; Protooncogene src, Rous Sarcoma; ASV; Tyrosine-Protein Kinase src-1; V-src Avian Sarcoma (Schmidt-Ruppin A-2) Viral Oncogene Homolog; Pp60c-src; Proto-Oncogene Tyrosine-Protein Kinase src; THC6;
Species:  
Mouse
Source:  
Sf9 insect cells
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Cat. No.: HY-P705884
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: src; Tyrosine Kinase Pp60c-src; Prev. src1; P60-src; C-src; Protooncogene src, Rous Sarcoma; ASV; Tyrosine-Protein Kinase src-1; V-src Avian Sarcoma (Schmidt-Ruppin A-2) Viral Oncogene Homolog; Pp60c-src; Proto-Oncogene Tyrosine-Protein Kinase src; THC6;
Species:  
Human
Source:  
sf9 insect cells
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Cat. No.: HY-P73422
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: src; Tyrosine Kinase Pp60c-src; Prev. src1; P60-src; C-src; Protooncogene src, Rous Sarcoma; ASV; Tyrosine-Protein Kinase src-1; V-src Avian Sarcoma (Schmidt-Ruppin A-2) Viral Oncogene Homolog; Pp60c-src; Proto-Oncogene Tyrosine-Protein Kinase src; THC6; src Proto-Oncogene, Non-Receptor Tyrosine Kinase; Proto-Oncogene C-src
Species:  
Human
Source:  
Sf9 insect cells
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Cat. No.: HY-P706166
Purity:  ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: src; Tyrosine Kinase Pp60c-src; Prev. src1; P60-src; C-src; Protooncogene src, Rous Sarcoma; ASV; Tyrosine-Protein Kinase src-1; V-src Avian Sarcoma (Schmidt-Ruppin A-2) Viral Oncogene Homolog; Pp60c-src; Proto-Oncogene Tyrosine-Protein Kinase src; THC6; src Proto-Oncogene, Non-Receptor Tyrosine Kinase; Proto-Oncogene C-src
Species:  
Human
Source:  
Sf9 insect cells
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