121 Results for "

vitamin K

" in MedChemExpress (MCE) Product Catalog:
Products (121)

121 Results for "vitamin K" in MCE Product Catalog:

Cat. No.: HY-B2172
CAS No.: 12001-79-5
Vitamin K, the blood-clotting vitamin, is important for the function of numerous proteins within the body, such as the coagulation factors, osteocalcin and matrix-Gla protein.
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32
32 Publications Verification
Cat. No.: HY-B0332
CAS No.: 58-27-5
Synonyms: vitamin K3
Menadione is a naphthoquinone that is converted into active vitamin K2 in the body. Menadione is a potential anticancer agent and radiosensitizer .
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8
8 Cited Publications
Cat. No.: HY-N0684
CAS No.: 84-80-0
Synonyms: Phylloquinone; Phytomenadione
Vitamin K1 a naturally occurring vitamin required for blood coagulation and bone and vascular metabolism.
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8
8 Cited Publications
Cat. No.: HY-B2156
CAS No.: 863-61-6
Synonyms: vitamin K2(MK-4); Menaquinone K4
Menaquinone-4 is a vitamin K, used as a hemostatic agent, and also a adjunctive therapy for the pain of osteoporosis.
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4
4 Cited Publications
Cat. No.: HY-P1918
CAS No.: 146340-20-7
Target:  

APC

Research Areas:  

Cardiovascular Disease

Activated Protein C (390-404), human is a polypeptide fragment of vitamin K-dependent serine protease activated protein C (APC), which inhibits the anticoagulant activity of APC. Activated Protein C (390-404), human inhibits APC-catalyzed inactivation of factor Va .
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3
3 Cited Publications
Cat. No.: HY-112499
CAS No.: 2124-57-4
Purity:  ≥98.0%
Synonyms: vitamin K2-7; vitamin K2(35); vitamin MK-7
Target:  

TGF-beta/Smad

Research Areas:  

Cardiovascular Disease

Menaquinone-7 (Vitamin K2-7), belongs to a class of K2-vitamin homologs (orally active), is originally discovered as the anti-hemorrhagic factors. Menaquinone-7 inhibits osteoclast bone resorption in vitro and stimulates bone formation in femoral tissue of aged female rats. Menaquinone-7 has a well-researched potential in the prevention of aging-induced bone degeneration. Menaquinone-7 is also a pharmacological option for activating Gla matrix protein and intervening in the progression of calcific aortic stenosis (CAVS) .
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3
3 Cited Publications
Cat. No.: HY-N6961
CAS No.: 84-79-7
Lapachol, a natural naphthoquinone, is an orally active, potent DHODH inhibitor. Lapachol has immunosuppressive activity on lymphocytes through its direct ability to block DHODH activity and inhibit pyrimidine synthesis. Lapachol is a vitamin K antagonist with antitumor activity and can inhibit DNA and RNA synthesis in neoplastic cells. Lapachol has anti-Leishmania activity .
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2
2 Cited Publications
Cat. No.: HY-B1897A
CAS No.: 130-37-0
Synonyms: Menadione sodium bisulfite; vitamin K3 sodium bisulfite
Target:  

Endogenous Metabolite

Research Areas:  

Others

Menadione bisulfite (sodium) is used as an agent to induce acute oxidative stress, and to function as a plant-defense activator against several pathogens.
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1
1 Cited Publications
Cat. No.: HY-W011474
CAS No.: 24034-73-9
Target:  

NF-κB

Geranylgeraniol is an orally acitve vitamin K2 sub-type, an intermediate of the mevalonate pathway. Geranylgeraniol targets NF-kB signaling pathway and could alleviate LPS-induced microglial inflammation in animal model .
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1
1 Cited Publications
Cat. No.: HY-16516
CAS No.: 1085703-32-7
Research Areas:  

Cancer

Vitamin CK3 is the combination of Vitamin C and vitamin K3 (100:1 ratio). Vitamin CK3 can decrease MMP activity. Vitamin CK3 can reactivate DNases and cause cell autophagy. Vitamin CK3 can be used for the research of cancer, such as lung cancer .
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1
1 Cited Publications
Cat. No.: HY-P74614
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PROS1; PS25; Prev. PROS; Truncated Protein S Alpha Variant; vitamin K-Dependent Protein S; Truncated Protein S Alpha; Protein S (Alpha); Protein S Alpha Variant; Protein Sa; PROS1 Protein; PS21; THPH5; PS22; THPH6; PS23; PSA; PS24; Protein S; vitamin K-De
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-B1508
CAS No.: 573-20-6
Synonyms: Acetomenaphthone
Target:  

Apoptosis

Research Areas:  

Infection Cancer

Vitamin K4 is a chemically synthesized Vitamin K which plays an important role in the normal blood coagulation system. Vitamin K4 arrests the cells in S phase and induces apoptosis. Vitamin K4 can be used for the research of cancer, such as prostate cancer and osteosarcoma .
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Cat. No.: HY-W017464
CAS No.: 50700-49-7
Synonyms: N-Acetyl-4-benzoquinone Imine
NAPQI is the toxic metabolite of Acetaminophen (HY-66005). NAPQI is also an inhibitor of enzymes in the vitamin K cycle. NAPQI is rapidly detoxified by glutathione (GSH), but in situations of GSH deficiency, excess NAPQI reacts with cysteine residues in proteins, causing cell death and toxicity in the liver .
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Cat. No.: HY-115243
CAS No.: 1010-60-2
Purity:  98.38%
Research Areas:  

Cancer

2-Chloro-1,4-naphthoquinone (chloro-K3) is a vitamin-K-dependent carboxylation antagonist with an IC50 value of 146 μM. 2-Chloro-1,4-naphthoquinone has cytotoxic activity .
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Cat. No.: HY-N2853
CAS No.: 7559-04-8
Synonyms: α-Tocopherylquinone
D-α-Tocopherylquinone (α-Tocopherylquinone) is a quinone, can be isolated from Phaeodactylum tricornutum. D-α-Tocopherylquinone is an oxidation product of α-Tocopherol (vitamin E). D-α-Tocopherylquinone can act as an anticoagulant and as an antioxidant. D-α-Tocopherylquinone reduces cellular oxidative damage produced by oxidized lipids. D-α-Tocopherylquinone binds to a liver cytosolic protein with a molecular mass of about 40 kDa. D-α-Tocopherylquinone binds to glurathione-S-transferase (GST) and can be transported to the site of metabolism or excreted in the bile .
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Cat. No.: HY-A0145
CAS No.: 435-97-2
Target:  

VD/VDR

Research Areas:  

Others Cancer

Phenprocoumon is a coumarin derivative that acts as a long acting oral anticoagulant and an antagonist of vitamin K.
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Cat. No.: HY-B1014
CAS No.: 152-72-7
Acenocoumarol is an anticoagulant that functions as a Vitamin K antagonist. Acenocoumarol inhibits MAPK/ERK/JNK signaling pathway, reduces the nuclear translocation of NF-κB p65, activates Akt/GSK3β signaling pathway. Acenocoumarol induces apoptosis in cell A549, arrests cell cycle at S phase .
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Cat. No.: HY-111186
CAS No.: 90035-08-8
Purity:  99.17%
Synonyms: WL 108366
Research Areas:  

Others

Flocoumafen (WL 108366) is an orally active vitamin K epoxide reductase inhibitor and a multi-target ligand, which includes prostaglandin F synthase, serum albumin, glucocorticoid receptor 2, and MMP-9. Flocoumafen is a second-generation anticoagulant rodenticide (ARs) with a half-life of 177.4 hours and has deadly anticoagulant effects .
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Cat. No.: HY-109569
CAS No.: 11032-49-8
Vitamin K2 is an orally active proliferation inhibitor. Vitamin K2 induces Autophagy and Apoptosis. Vitamin K2 reduces the levels of proinflammatory cytokines (such as IL-1β, TNF-α, and IL-6). Vitamin K2 inhibits cell growth in leukemia cells. Vitamin K2 can be used for the research of involutional osteoporosis, non-alcoholic fatty liver disease, ulcerative colitis, acute myeloid leukemia, myelodysplastic syndromes, and hepatocellular carcinoma .
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Cat. No.: HY-N2552
CAS No.: 130-24-5
Research Areas:  

Infection Cancer

Vitamin K5 hydrochloride is a photosensitizer and a antimicrobial agent. Vitamin K5 hydrochloride is a specific PKM2 inhibitor with IC50 values of 28, 191 and 120 μM for PKM2, PKM1 and PKL. Vitamin K5 hydrochloride induces apoptosis of colon 26 cells. Vitamin K5 hydrochloride can be used for the research of infection and cancer, and it also can be used as a preservative for pharmaceuticals, foods, and beverages .
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