DPC 961
DPC 961 (DMP 961) is a non-nucleoside reverse transcriptase inhibitor (NNRTI). DPC 961 is a potent and specific inhibitor of HIV-1 reverse transcriptase, which inhibits the activity of HIV-1 reverse transcriptase in a non-competitive manner, thereby preventing viral replication. DPC 961 can be used for research on AIDS.
For research use only. We do not sell to patients.
- CAS No.: 214287-88-4
- Formula: C14H10ClF3N2O
- Molecular Weight:314.69
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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CAS No. 214287-88-4
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Molecular Weight 314.69
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Formula C14H10ClF3N2O
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SMILES
FC(F)(F)[C@@]1(C2=CC(Cl)=CC=C2NC(N1)=O)C#CC3CC3
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Synonyms
(S)-DPC 961; DMP 961
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Mutlib A, et al. Characterization of Novel Glutathione Adducts of a Non-Nucleoside Reverse Transcriptase Inhibitor,(S)-6-Chloro-4-(cyclopropylethynyl)-4-(trifluoromethyl)-3, 4-dihydro-2 (1 H)-quinazolinone (DPC 961), in Rats. Possible Formation of an Oxirene Metabolic Intermediate from a Disubstituted Alkyne[J]. Chemical research in toxicology, 2000, 13(8): 775-784. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)