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Cat. No.: HY-183459

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LB 11058

LB 11058 is a Cephalosporin Antibacterial agent. LB 11058 inhibits the growth of pathogenic bacteria, including multidrug-resistant staphylococci and streptococci, but shows weak activity against Enterococcus faecium, Corynebacterium species, Enterobacteriaceae and non-fermenting Gram-negative bacilli. LB 11058 can be used in bacterial infection research.

For research use only. We do not sell to patients.

CAS No.: 591207-81-7
Formula: C₁₈H₁₅ClN₈O₆S₃
Molecular Weight:571.01

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

LB 11058 Chemical Structure

CAS No.: 591207-81-7

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
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Biological Activity

Description

All Antibiotic Isoforms :

In Vitro

Bacterial Infection

LB 11058 (0.008-64 μg/mL) exhibits potent in vitro activity against most tested Gram-positive isolates, with MIC₉₀ values ≤1 μg/mL for β-hemolytic streptococci, penicillin-susceptible/resistant viridans streptococci, Oxacillin (HY-B0925A)-susceptible/resistant S. aureus, Oxacillin-susceptible/resistant coagulase-negative staphylococci (CoNS), vancomycin (HY-B0671)-nonsusceptible staphylococci, and Vancomycin-susceptible/resistant E. faecalis; it shows weak activity against E. faecium, Enterococcus spp., Bacillus spp., and Corynebacterium spp.^[1]

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Related Protocols :

Chemical Information

CAS No. 591207-81-7
Molecular Weight 571.01
Formula C₁₈H₁₅ClN₈O₆S₃
SMILES

OC(C1=C(/C=C/SC2=CC(N=C(N2)N)=O)CS[C@@]([C@@H]3NC(/C(C4=C(SC(N)=N4)Cl)=N\O)=O)([H])N1C3=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Sader HS, et al. In vitro activities of the novel cephalosporin LB 11058 against multidrug-resistant Staphylococci and Streptococci. Antimicrobial agents and chemotherapy. 2004 Jan;48(1):53-62. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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