SGLT2-IN-5
SGLT2-IN-5 (Compound 99) is an orally active SGLT2 inhibitor with IC₅₀ values for SGLT2, SGLT1, and DPP4 of 0.8, 23, and 58 nM respectively. SGLT2-IN-5 controls blood sugar levels in diabetic rat models and increases the levels of active GLP-1. SGLT2-IN-5 can be used for the study of type 2 diabetes.
For research use only. We do not sell to patients.
- Formula: C33H43F2N3O6
- Molecular Weight:615.71
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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SGLT2 0.8 nM (IC50) |
SGLT1 23 nM (IC50) |
DPP-4 58 nM (IC50) |
Chemical Information
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Molecular Weight 615.71
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Formula C33H43F2N3O6
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SMILES
FC1(F)CN(C(CNC(C)(CCCOC2=CC=C(CC3=CC([C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)C)O)O)O)=CC=C3C)C=C2)C)=O)[C@H](C#N)C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)