SIRT2-IN-13
SIRT2-IN-13 (compound 7c) is an inhibitor of SIRT2 and induces apoptosis. SIRT2-IN-13 selectively inhibits colon cancer and leukemia cells and arrests the cell cycle in the G2 phase.
For research use only. We do not sell to patients.
- Formula: C31H31N3S
- Molecular Weight:477.66
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
SIRT2[1]
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Panel NCI-60 (60 carcinoma cell lines) | GI50 |
0.22 μM
Compound: 7b
|
Growth inhibition of human Panel NCI-60 (60 carcinoma cell lines) cells incubated for 48 hrs by SRB assay
Growth inhibition of human Panel NCI-60 (60 carcinoma cell lines) cells incubated for 48 hrs by SRB assay
|
[PMID: 38484678] |
Chemical Information
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Molecular Weight 477.66
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Formula C31H31N3S
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SMILES
CN(C)C1=CC(CNCCSC2(C3=CC=CC=C3)C4=C(C=CC=C4)C=CC5=C2C=CC=C5)=NC=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)