SM27
SM27 (NSC 37204) is an inhibitor for fibroblast growth factors (FGF). SM27 inhibits angiogenesis through block of FGF2/HSPGs/FGFR1 complex formation.
For research use only. We do not sell to patients.
- CAS No.: 6266-54-2
- Formula: C21H16N2O9S2
- Molecular Weight:504.49
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
SM27 (0-100 μM, 2 h) inhibits FGF2/heparin and FGF2/ FGFR1 interaction in a dose-dependent way with IC50s of 3.5 and 4 mM, through inhibition of FGF2-mediated cell-cell adhesion with IC50 of 1 mM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 6266-54-2
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Molecular Weight 504.49
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Formula C21H16N2O9S2
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SMILES
O=S(C1=CC(O)=C2C=C(C=CC2=C1)NC(NC3=CC=C4C=C(C=C(C4=C3)O)S(=O)(O)=O)=O)(O)=O
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Synonyms
NSC 37204
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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