SOS1-IN-13
SOS1-IN-13 is a potent son of sevenless homolog 1 (SOS1) inhibitor with IC50s of 6.5 nM and 327 nM for SOS1 and pERK, respectively. SOS1-IN-13 can be used for researching anticancer.
For research use only. We do not sell to patients.
- CAS No.: 2654741-45-2
- Formula: C21H22F3N3O2
- Molecular Weight:405.41
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
IC50: 6.5 nM (SOS1), 327 nM (pERK)[1]
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| MKN-1 | IC50 |
195 nM
Compound: 16
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Antiproliferative activity against human MKN-1 cells assessed as reduction in cell viability measured for 48 hrs by CCK-8 assay
Antiproliferative activity against human MKN-1 cells assessed as reduction in cell viability measured for 48 hrs by CCK-8 assay
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[PMID: 38430853] |
Chemical Information
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CAS No. 2654741-45-2
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Molecular Weight 405.41
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Formula C21H22F3N3O2
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SMILES
COC1=C(C=C2C(C(C)=NN=C2N[C@@H](C3=CC=CC(C(F)(F)F)=C3C)C)=C1)OC
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
SOS1-IN-13 Related Classifications
HY-144967 Related Classifications
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