2. Epigenetics
  3. Histone Acetyltransferase
  4. SPV106

SPV106 is histone acetylase (HAT) and GCN5-related N-acetyltransferases (GNAT) activator. SPV106 can be used for the research of type 2 diabetes (T2D).

For research use only. We do not sell to patients.

SPV106 Chemical Structure

SPV106 Chemical Structure

CAS No. : 1036939-38-4

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Based on 1 publication(s) in Google Scholar

SPV106 Related Antibodies

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Description

SPV106 is histone acetylase (HAT) and GCN5-related N-acetyltransferases (GNAT) activator. SPV106 can be used for the research of type 2 diabetes (T2D)[1].

In Vitro

SPV106 restores normal levels of H3K9Ac and H3K14Ac, reduces DNA CpG hypermethylation, and recovers D-CMSC proliferation and differentiation[1].
SPV106 (5 µmol/L) reduces cellular senescence and induces cKit expression in D-CMSC[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

SPV106 Related Antibodies

Western Blot Analysis[1]

Cell Line: Human cardiac-specific mesenchymal cell (CMSC)
Concentration: 25 μmol/L
Incubation Time: 6-8 days
Result: Achieved partial but significant rescue of HAT activity.

RT-PCR[1]

Cell Line: Human cardiac-specific mesenchymal cell (CMSC)
Concentration: 25 μmol/L
Incubation Time: 7 days
Result: Not associated to a rescue in gene transcription.
Molecular Weight

368.55

Formula

C22H40O4
CAS No.
SMILES

O=C(OCC)/C(C(OCC)=O)=C/CCCCCCCCCCCCCC
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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SPV106 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SPV1061036939-38-4SPV 106SPV-106Histone AcetyltransferaseHATsHAThistone acetylase (HAT)GCN5-related N-acetyltransferases (GNAT)type 2 diabetes (T2D)Inhibitorinhibitorinhibit

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HY-114566
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