STAT3-IN-43
STAT3-IN-43 (Compound K2) is a covalent inhibitor targeting the allosteric site at the junction of the STAT3 coiled-coil domain and DNA-binding domain, with an IC50 of 40.7 μM. STAT3-IN-43 can be used in cancer research.
For research use only. We do not sell to patients.
- CAS No.: 2761657-21-8
- Formula: C17H19BrN2O4
- Molecular Weight:395.25
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
IC50 & Target
[1]|
STAT3 40.7 μM (IC50) |
Chemical Information
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CAS No. 2761657-21-8
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Molecular Weight 395.25
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Formula C17H19BrN2O4
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SMILES
BrC1=CC(CNC(C2CCCN(C(C=C)=O)C2)=O)=CC3=C1OCO3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
STAT3-IN-43 Related Classifications
HY-174386 Related Classifications
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