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Cat. No.: HY-FLB1019

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Sulpiride solution

Sulpiride solution is mainly composed of Sulpiride (HY-B1019). Sulpiride is an orally active dopamine D2/D3 receptor antagonist. Sulpiride is an atypical antipsychotic agent of the benzamide family. Sulpiride can be used in research into anxiety, depression and breast cancer.

For research use only. We do not sell to patients.

CAS No.: 15676-16-1
Formula: C₁₅H₂₃N₃O₄S
Molecular Weight:341.43

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Sulpiride solution Chemical Structure

CAS No.: 15676-16-1

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

All Dopamine Receptor Isoforms :

Chemical Information

CAS No. 15676-16-1
Molecular Weight 341.43
Formula C₁₅H₂₃N₃O₄S
SMILES

O=C(C1=CC(S(=O)(N)=O)=CC=C1OC)NCC2N(CCC2)CC
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Protocols

All Animals and Diseases

Breast Cancer Modeling
Breast cancer is a heterogeneous cancer, and it has been distinguished into four subtypes: luminal A, luminal B, HER2-positive and basal-like. Molecular mutations, epigenetic alterations, hormone exposure and immune microenvironment are related to the progression of breast cancer.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Rüther, E et al. Antidepressant action of sulpiride. Results of a placebo-controlled double-blind trial. Pharmacopsychiatry vol. 32,4 (1999): 127-35. [Content Brief]

[2]. Jaworski, J N et al. Effect of dopamine D2/D3 receptor antagonist sulpiride on amphetamine-induced changes in striatal extracellular dopamine. European journal of pharmacology vol. 418,3 (2001): 201-6. [Content Brief]

[3]. Zarrindast, Mohammad-Reza et al. Synergistic effect between quinpirole and L-NAME as well as sulpiride and L-arginine on the modulation of anxiety and memory processes in the 6-OHDA mouse model of Parkinson's disease: An isobologram analysis. Neurobiology of learning and memory vol. 186 (2021): 107538. [Content Brief]

[4]. Li, Jian et al. Dopamine D2 receptor antagonist sulpiride enhances dexamethasone responses in the treatment of drug-resistant and metastatic breast cancer. Acta pharmacologica Sinica vol. 38,9 (2017): 1282-1296. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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