1. Anti-infection
  2. Parasite
  3. T.cruzi-IN-1

T.cruzi-IN-1 

Cat. No.: HY-103033
Handling Instructions

T.cruzi-IN-1 is a potent Trypanosoma cruzi inhibitor with an IC50 of 8 nM. T.cruzi-IN-1, a 4-trifluoromethyl substituted analog, has the potential for both the acute and chronic stages of Chagas disease.

For research use only. We do not sell to patients.

T.cruzi-IN-1 Chemical Structure

T.cruzi-IN-1 Chemical Structure

CAS No. : 1350920-22-7

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Description

T.cruzi-IN-1 is a potent Trypanosoma cruzi inhibitor with an IC50 of 8 nM. T.cruzi-IN-1, a 4-trifluoromethyl substituted analog, has the potential for both the acute and chronic stages of Chagas disease[1].

IC50 & Target

IC50: 8 nM (Trypanosoma cruzi)[1]

In Vitro

T.cruzi-IN-1 inhibits Trypanosoma cruzi replication and has an IC50 of 61.6 μM for toxicity[1].

Molecular Weight

390.44

Formula

C₂₂H₂₅F₃N₂O

CAS No.

1350920-22-7

SMILES

O=C(C1CN(CC2=CC=C(C(F)(F)F)C=C2)CCC1)N(C)CC3=CC=CC=C3

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Keywords:

T.cruzi-IN-1ParasiteTrypanosomacruzi4-trifluoromethylsubstitutedacutechronicChagasdiseaseInhibitorinhibitorinhibit

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