1. PROTAC
  2. Ligands for E3 Ligase
  3. Thalidomide 4'-ether-PEG1-azide

Thalidomide 4'-ether-PEG1-azide is the Thalidomide (HY-14658)-based cereblon ligand used in the recruitment of CRBN protein. Thalidomide 4'-ether-PEG1-azide can be connected to the ligand for protein by a linker to form PROTACs.

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Thalidomide 4'-ether-PEG1-azide Chemical Structure

Thalidomide 4'-ether-PEG1-azide Chemical Structure

CAS No. : 2758432-02-7

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Description

Thalidomide 4'-ether-PEG1-azide is the Thalidomide (HY-14658)-based cereblon ligand used in the recruitment of CRBN protein. Thalidomide 4'-ether-PEG1-azide can be connected to the ligand for protein by a linker to form PROTACs[1].

Molecular Weight

387.35

Formula

C17H17N5O6

CAS No.
SMILES

[N-]=[N+]=NCCOCCOC1=CC=CC(C(N2C3C(NC(CC3)=O)=O)=O)=C1C2=O

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Thalidomide 4'-ether-PEG1-azide Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Thalidomide 4'-ether-PEG1-azide
Cat. No.:
HY-157514
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