1. PROTAC
  2. Ligand for E3 Ligase
  3. Thalidomide-O-C8-COOH

Thalidomide-O-C8-COOH 

Cat. No.: HY-130952 Purity: 95.30%
Handling Instructions

Thalidomide-O-C8-COOH is the Thalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Thalidomide-O-C8-COOH (Cereblon ligand 3) can be connected to the ligand for protein by a linker to form PROTACs.

For research use only. We do not sell to patients.

Thalidomide-O-C8-COOH Chemical Structure

Thalidomide-O-C8-COOH Chemical Structure

CAS No. : 2225148-51-4

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100 mg USD 680 In-stock
Estimated Time of Arrival: December 31
500 mg USD 1800 In-stock
Estimated Time of Arrival: December 31
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Description

Thalidomide-O-C8-COOH is the Thalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Thalidomide-O-C8-COOH (Cereblon ligand 3) can be connected to the ligand for protein by a linker to form PROTACs[1].

IC50 & Target[1]

Cereblon

 

Molecular Weight

430.45

Formula

C₂₂H₂₆N₂O₇

CAS No.

2225148-51-4

SMILES

O=C(O)CCCCCCCCOC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

References
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Keywords:

Thalidomide-O-C8-COOHLigand for E3 LigaseE3 ligase-recruiting MoietyInhibitorinhibitorinhibit

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Thalidomide-O-C8-COOH
Cat. No.:
HY-130952
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