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Tigatuzumab

(Synonyms: CS-1008; Anti-Human TRAIL-R2 Recombinant Antibody)
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Based on 1 Customer Validation

Tigatuzumab (CS-1008) is a humanized IgG1 monoclonal antibody targets death receptor 5 (DR5). Tigatuzumab induces cell apoptosis of cancer cells and inhibits tumor growth in vivo. Tigatuzumab can be used for the research of cancer.

For research use only. We do not sell to patients.

  • Purity: 98.18%
  • CAS No.: 918127-53-4
  • Molecular Weight:144.64 kDa
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Tigatuzumab
  • Experimental Validation Results for Tigatuzumab
  • Experimental Validation Results for Tigatuzumab
  • Tigatuzumab Chemical Structure
  • Experimental Validation Results for Tigatuzumab
  • Experimental Validation Results for Tigatuzumab
  • Experimental Validation Results for Tigatuzumab
  • Tigatuzumab Chemical Structure
    Tigatuzumab Chemical Structure
CAS No.: 918127-53-4
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To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    Human IgG1 kappa

  • 1/16

    Immobilized TRAIL R2/TNFRSF10B Protein, Human (HY-P72779) can bind Tigatuzumab. The EC50 for this effect is 4.074 ng/mL.

  • 1/16

    Flow cytometric analysis of 1.5X106 HEPG2 cells with Tigatuzumab (HY-P99270, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa, Isotype Control (HY-P99001, blue) was used as the isotype control.

  • Tigatuzumab Chemical Structure
    1/16
  • Tigatuzumab
  • Immobilized TRAIL R2/TNFRSF10B Protein, Human (HY-P72779) can bind Tigatuzumab. The EC50 for this effect is 4.074 ng/mL.
  • Flow cytometric analysis of 1.5X106 HEPG2 cells with Tigatuzumab (HY-P99270, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa, Isotype Control (HY-P99001, blue) was used as the isotype control.