TLR7 agonist 27
TLR7 agonist 27 (compound 24) is a potent TLR7 agonist with an EC50 of 238.1 nM. TLR7 agonist 27 shows weak agonistic activity against NOD2 (nucleotide-binding oligomerization domain 2) (EC50 of 6.2 μM). TLR7 agonist 27 is a potent immunostimulant, and can be used as a vaccine adjuvant and/or immunotherapeutic.
For research use only. We do not sell to patients.
- Formula: C47H64N10O11
- Molecular Weight:945.07
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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TLR7 238.1 nM (EC50) |
NOD2 6156 nM (EC50) |
Chemical Information
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Molecular Weight 945.07
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Formula C47H64N10O11
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SMILES
COC1=C(O)C=CC(/C=C/C(NCC(N[C@H](C(N[C@@H](C(OCC)=O)CCC(NCCCCCCNC(C(C=C2)=CC=C2CN3C4=NC(OCCCC)=NC(N)=C4N=C3O)=O)=O)=O)C(C)C)=O)=O)=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
TLR7 agonist 27 Related Classifications
HY-168159 Related Classifications
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