Trk-IN-11
Trk-IN-11 (Compound 14h) is a potent inhibitor of TRK (IC50 = 1.4, 1.8 nM, against TrkA, TrkAG595R, respectively). As a receptor tyrosine kinase (RTK), tropomyosin receptor kinase (Trk) is a key agent target in solid tumors. Trk-IN-11 has the potential for the research of cancer disease.
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- CAS. Nr.: 2700265-62-7
- Formel: C21H22FN5O3
- Molecular Weight:411.43
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
Beschreibung
IC50 & Target
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TrkA |
Chemical Information
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CAS. Nr. 2700265-62-7
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Molecular Weight 411.43
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Formel C21H22FN5O3
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SMILES
C[C@H]1N2C3=NC4=C(C(NC(C)(COC5=CC(F)=CC=C5C2)C)=O)C=NN4C=C3OC1
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)