Trk-IN-11
Trk-IN-11 (Compound 14h) is a potent inhibitor of TRK (IC50 = 1.4, 1.8 nM, against TrkA, TrkAG595R, respectively). As a receptor tyrosine kinase (RTK), tropomyosin receptor kinase (Trk) is a key agent target in solid tumors. Trk-IN-11 has the potential for the research of cancer disease.
For research use only. We do not sell to patients.
- CAS No.: 2700265-62-7
- Formula: C21H22FN5O3
- Molecular Weight:411.43
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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TrkA |
Chemical Information
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CAS No. 2700265-62-7
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Molecular Weight 411.43
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Formula C21H22FN5O3
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SMILES
C[C@H]1N2C3=NC4=C(C(NC(C)(COC5=CC(F)=CC=C5C2)C)=O)C=NN4C=C3OC1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)