2. Metabolic Enzyme/Protease
  3. PAI-1
  4. UCD74A hydrochloride

UCD74A (compound 18) hydrochloride is a 5-substituted amiloride analog and urokinase-type plasminogen activator (uPA) inhibitor with an IC50 of 110 μM.UCD74A (hydrochloride) modulates plasminogen activation cascades linked to extracellular matrix remodeling.UCD74A (hydrochloride) can be used for the research of tumor metastasis.

For research use only. We do not sell to patients.

UCD74A hydrochloride

UCD74A hydrochloride Chemical Structure

CAS No. : 1345838-99-4

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UCD74A hydrochloride Related Antibodies

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Description

UCD74A (compound 18) hydrochloride is a 5-substituted amiloride analog and urokinase-type plasminogen activator (uPA) inhibitor with an IC50 of 110 μM.UCD74A (hydrochloride) modulates plasminogen activation cascades linked to extracellular matrix remodeling.UCD74A (hydrochloride) can be used for the research of tumor metastasis[1].

In Vitro

UCD74A (compound 18) hydrochloride (serial dilutions; duration within the linear region of absorbance vs time plots) inhibits high molecular weight urokinase-type plasminogen activator (HMW-uPA) with an IC50 of 110 μM in an in vitro enzyme assay[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

UCD74A hydrochloride Related Antibodies
Molecular Weight

324.12

Formula

C8H11Cl2N7O3
CAS No.
SMILES

O=C(CNC1=NC(N)=C(N=C1Cl)C(NC(N)=N)=O)O.Cl
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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UCD74A hydrochloride Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

UCD74A1345838-99-4PAI-1Plasminogen activator inhibitor-1plasminogen activation cascadeshigh molecular weight urokinase-type plasminogen activatorHMW-uPAuPAextracellular matrix remodelingurokinase-type plasminogen activatortumor metastasisInhibitorinhibitorinhibit

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UCD74A hydrochloride
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HY-123685
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