UK 343664
UK 343664 is a potent, orally active and selective PDE5 inhibitor. UK 343664 partially reverses Thromboxane-induced pulmonary hypertension.
For research use only. We do not sell to patients.
- CAS No.: 215297-27-1
- Formula: C28H35N7O4S
- Molecular Weight:565.69
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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PDE5 |
Chemical Information
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CAS No. 215297-27-1
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Molecular Weight 565.69
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Formula C28H35N7O4S
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SMILES
O=C1N=C(C2=C(OCCC)C=CC(S(=O)(N3CCN(CC3)CC)=O)=C2)NC4=C(CC)N(CC5=NC=CC=C5)N=C41
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Walker DK, et al. Pharmacokinetics and metabolism of a selective PDE5 inhibitor (UK-343,664) in rat and dog. Xenobiotica. 2001 Aug-Sep;31(8-9):651-64. [Content Brief]
[2]. Urdaneta F, et al. Effects of a new phosphodiesterase enzyme type V inhibitor (UK 343-664) versus milrinone in a porcine model of acute pulmonary hypertension. Ann Thorac Surg. 2004 Oct;78(4):1433-7. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
UK 343664 Related Classifications
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