Umedaptanib pegol sodium
Based on 1 Customer Validation
Umedaptanib pegol sodium is a pegylated aptamer, which can target fibroblast growth factor-2 (FGF2). It is used for the study of neovascular age-related macular degeneration (nAMD).
For research use only. We do not sell to patients.
- Purity : 93.39%
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Storage:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Biological Activity
Description
Chemical Information
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Appearance Solid
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Color White to off-white
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SMILES
[Umedaptanib pegol (sodium)]
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Synonyms
RBM-007 sodium
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Purity & Documentation
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Data Sheet (268 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (1518 KB)
References
[1]. Pereira DS, Akita K, Bhisitkul RB, et al. Safety and tolerability of intravitreal umedaptanib pegol (anti-FGF2) for neovascular age-related macular degeneration (nAMD): a phase 1, open-label study. Eye (Lond). 2024;38(6):1149-1154. [Content Brief]
[2]. Matsuda Y, Nonaka Y, Futakawa S, et al. Anti-Angiogenic and Anti-Scarring Dual Action of an Anti-Fibroblast Growth Factor 2 Aptamer in Animal Models of Retinal Disease. Mol Ther Nucleic Acids. 2019;17:819-828. [Content Brief]
[3]. Kimura T, Bosakova M, Nonaka Y, et al. An RNA aptamer restores defective bone growth in FGFR3-related skeletal dysplasia in mice. Sci Transl Med. 2021;13(592):eaba4226. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)