UBAP2 - ubiquitin associated protein 2 Gene

Also Known as UBAP-2

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 55833

About UBAP2

This gene has 27 transcripts (splice variants), 294 orthologues and 1 paralogue. Broad expression in testis (RPKM 18.9), adrenal (RPKM 7.6) and 25 other tissues.

Summary

The protein encoded by this gene contains a UBA (ubiquitin associated) domain, which is characteristic of proteins that function in the ubiquitination pathway. This gene may show increased expression in the adrenal gland and lymphatic tissues. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]

UBAP2 Products (9)

mRNA Protein Name
NM_001282530.2 NP_001269459.1 ubiquitin-associated protein 2 isoform 5
NM_001370059.2 NP_001356988.2 ubiquitin-associated protein 2 isoform 1
NM_001370062.2 NP_001356991.2 ubiquitin-associated protein 2 isoform 1
NM_001370064.2 NP_001356993.2 ubiquitin-associated protein 2 isoform 8
NM_001370066.2 NP_001356995.2 ubiquitin-associated protein 2 isoform 6
NM_001370067.2 NP_001356996.2 ubiquitin-associated protein 2 isoform 7
NM_001370068.2 NP_001356997.2 ubiquitin-associated protein 2 isoform 6
NM_018449.4 NP_060919.4 ubiquitin-associated protein 2 isoform 1
NM_020867.2 NP_065918.1 ubiquitin-associated protein 2 isoform 7

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

UBAP2 Protein Structure

UBA

UBA: UBA/TS-N domain (54 - 89)

DUF3697

DUF3697: Ubiquitin-associated protein 2 (512 - 544)

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  • 1119 a.a.
Protein Preferred Names Protein Names

ubiquitin-associated protein 2

  • AD-012 protein

UBAP2 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
UBAP2 Q5T6F2 BANP Homo sapiens Q8N9N5-2
Validated Y2H
32296183
Intra
UBAP2 Q5T6F2 ATPAF2 Homo sapiens Q8N5M1
Validated Y2H
32296183
Intra
UBAP2 Q5T6F2 IGFN1 Homo sapiens Q86VF2-5
Validated Y2H
32296183
Intra
UBAP2 Q5T6F2 SPAG8 Homo sapiens Q99932-2
Validated Y2H
32296183
Intra
UBAP2 Q5T6F2 KRTAP15-1 Homo sapiens Q3LI76
Y2H Prey Pooling
32296183
Intra
UBAP2 Q5T6F2 KRTAP15-1 Homo sapiens Q3LI76
Y2H Array
32296183
Intra
UBAP2 Q5T6F2 ASB13 Homo sapiens Q8WXK3-2
Validated Y2H
32296183
Intra
UBAP2 Q5T6F2 NOXA1 Homo sapiens Q86UR1-2
Validated Y2H
32296183
Intra
UBAP2 Q5T6F2 C10orf55 Homo sapiens Q5SWW7
Y2H Prey Pooling
32296183
Intra
UBAP2 Q5T6F2 C10orf55 Homo sapiens Q5SWW7
Y2H Array
32296183
Intra
UBAP2 Q5T6F2 CREM Homo sapiens Q03060-25
Y2H Prey Pooling
32296183
Intra
UBAP2 Q5T6F2 CREM Homo sapiens Q03060-25
Y2H Array
32296183
Intra
UBAP2 Q5T6F2 KANK2 Homo sapiens Q63ZY3
Validated Y2H
32296183
Intra
UBAP2 Q5T6F2 WRAP53 Homo sapiens Q9BUR4
Validated Y2H
32296183
Intra
UBAP2 Q5T6F2 TFG Homo sapiens Q92734
Validated Y2H
32296183
Intra
UBAP2 Q5T6F2 RHOXF2 Homo sapiens Q9BQY4
Validated Y2H
32296183
Intra
UBAP2 Q5T6F2 PLEKHB2 Homo sapiens Q96CS7
Y2H Prey Pooling
32296183
Intra
UBAP2 Q5T6F2 PLEKHB2 Homo sapiens Q96CS7
Validated Y2H
32296183
Intra
UBAP2 Q5T6F2 PLEKHB2 Homo sapiens Q96CS7
Y2H Array
32296183
Intra
UBAP2 Q5T6F2 NPAS2 Homo sapiens Q99743
Validated Y2H
32296183
Intra
UBAP2 Q5T6F2 DAZAP2 Homo sapiens Q15038
Y2H Prey Pooling
32296183
Intra
UBAP2 Q5T6F2 DAZAP2 Homo sapiens Q15038
Y2H Array
32296183
Intra
UBAP2 Q5T6F2 RBPMS Homo sapiens Q93062-3
Validated Y2H
32296183
Intra
UBAP2 Q5T6F2 OTX1 Homo sapiens P32242
Y2H Prey Pooling
32296183
Intra
UBAP2 Q5T6F2 SPMIP9 Homo sapiens Q96LM6
Validated Y2H
32296183
Intra
UBAP2 Q5T6F2 q96ej4_human Homo sapiens Q96EJ4
Validated Y2H
32296183
Intra
UBAP2 Q5T6F2 TENT5B Homo sapiens Q96A09
Validated Y2H
32296183
Intra
UBAP2 Q5T6F2 SHC3 Homo sapiens Q92529
Validated Y2H
32296183
Intra
UBAP2 Q5T6F2 TEP1 Homo sapiens Q99973
Validated Y2H
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15329 UBAP2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS15330 UBAP2L Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta UBAP2 VGNC VGNC:78949
Bos taurus UBAP2 VGNC VGNC:36572
Rattus norvegicus UBAP2 RGD RGD:1311717
Canis familiaris UBAP2 VGNC VGNC:48046
Felis catus UBAP2 VGNC VGNC:66753
Mus musculus UBAP2 MGD MGI:1916176
Others UBAP2 NCBI