Tec
The Tec family of non-receptor tyrosine kinases contains five mammalian members: BTK, ITK, TEC, TXK (RLK) and BMX (ETK). A hallmark is the N-terminal pleckstrin-homology domain (replaced by cysteine-rich regions in TXK) that binds phosphoinositides and recruits the kinases to the plasma membrane upon PIP3 generation. Tec kinases act downstream of antigen receptors, toll-like receptors and integrins in B cells, T cells, macrophages and platelets, phosphorylating PLCγ to generate calcium and diacylglycerol signals. BTK mutations cause X-linked agammaglobulinemia, proving BTK's essential role in B-cell development. Bruton tyrosine kinase inhibitors such as ibrutinib, acalabrutinib and zanubrutinib revolutionized therapy of B-cell malignancies.
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Tec Recombinant Proteins (24)
BTK Protein, Human (Active, sf9, C-His)
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Cat. No.: HY-P705642
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: BTK; Tyrosine-Protein Kinase BTK Isoform (Lacking Exon 13 To 17); Prev. AGMX1; Tyrosine-Protein Kinase BTK Isoform (Lacking Exon 14); Prev. IMD1; Tyrosine-Protein Kinase BTK Isoform 52; ATK; Tyrosine-Protein Kinase BTK Isoform 51; PSCTK1; Tyrosine-Protein
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BTK Protein, Human (Active, Biotinylated, C481S, sf9, His, Avi)
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Cat. No.: HY-P702730
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: BTK; Tyrosine-Protein Kinase BTK Isoform (Lacking Exon 13 To 17); Prev. AGMX1; Tyrosine-Protein Kinase BTK Isoform (Lacking Exon 14); Prev. IMD1; Tyrosine-Protein Kinase BTK Isoform 52; ATK; Tyrosine-Protein Kinase BTK Isoform 51; PSCTK1; Tyrosine-Protein
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TEC Protein, Human (Active, sf9, GST)
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Cat. No.: HY-P701643
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: TEC; PSCTK4; Tec Protein Tyrosine Kinase; Tyrosine-Protein Kinase Tec
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ITK Protein, Mouse (sf9, His-GST)
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Cat. No.: HY-P74795
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: ITK; T-Cell-Specific Kinase; IL2 Inducible T Cell Kinase; Kinase EMT; EMT; Homolog Of Mouse T-Cell Itk/Tsk; LYK; IL2-Inducible T-Cell Kinase; PSCTK2; IL2 Inducible T-Cell Kinase; Interleukin-2-Inducible T-Cell Kinase; Tyrosine-Protein Kinase LYK; Tyrosine-Protein Kinase ITK/TSK; Tyrosine-Protein Kinase Lyk; IL-2-Inducible T-Cell Kinase; LPFS1
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BTK Protein, Human (Active, sf9)
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Cat. No.: HY-P705742
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: BTK; Tyrosine-Protein Kinase BTK Isoform (Lacking Exon 13 To 17); Prev. AGMX1; Tyrosine-Protein Kinase BTK Isoform (Lacking Exon 14); Prev. IMD1; Tyrosine-Protein Kinase BTK Isoform 52; ATK; Tyrosine-Protein Kinase BTK Isoform 51; PSCTK1; Tyrosine-Protein
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BTK Protein, Human (Active, Biotinylated, sf9, Avi)
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Cat. No.: HY-P705744
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: BTK; Tyrosine-Protein Kinase BTK Isoform (Lacking Exon 13 To 17); Prev. AGMX1; Tyrosine-Protein Kinase BTK Isoform (Lacking Exon 14); Prev. IMD1; Tyrosine-Protein Kinase BTK Isoform 52; ATK; Tyrosine-Protein Kinase BTK Isoform 51; PSCTK1; Tyrosine-Protein
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TXK Protein, Human (sf9, 268a.a, His, GST)
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Cat. No.: HY-P701655
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: TXK; PTK4; RLK; Tyrosine-protein kinase TXK; EC 2.7.10.2; Protein-tyrosine kinase 4; Resting lymphocyte kinase; Tyrosine Kinase; Tyrosine-Protein Kinase; PTK4 Protein Tyrosine Kinase 4; TKL; BTKL; PSCTK5; TXK Tyrosine Kinase
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BTK Protein, Human (Active, sf9, GST)
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Cat. No.: HY-P704025
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: BTK; Tyrosine-Protein Kinase BTK Isoform (Lacking Exon 13 To 17); Prev. AGMX1; Tyrosine-Protein Kinase BTK Isoform (Lacking Exon 14); Prev. IMD1; Tyrosine-Protein Kinase BTK Isoform 52; ATK; Tyrosine-Protein Kinase BTK Isoform 51; PSCTK1; Tyrosine-Protein Kinase BTK Isoform 65; XLA; Non-Specific Protein-Tyrosine Kinase; Bruton Agammaglobulinemia Tyrosine Kinase; Agammaglobulinaemia Tyrosine Kinase; Tyrosine-Protein Kinase BTK; Agammaglobulinemia Tyrosine Kinase; Bruton'S Tyrosine Kinase; BTK Kinase Deficient Isoform 8; B-Cell Progenitor Kinase; BTK Kinase Deficient Isoform 4; BPK; BTK Kinase Deficient Isoform 1; Dominant-Negative Kinase-Deficient Brutons Tyrosine Kinase Isoform 10; Tyrosine-Protein Kinase; Dominant-Negative Kinase-Deficient Brutons Tyrosine Kinase Isoform 8; IGHD3; Dominant-Negative Kinase-Deficient Brutons Tyrosine Kinase Isoform 1; AT; Tyrosine-Protein Kinase BTK Isoform (Lacking Exon 15 To 18); Bruton Tyrosine Kinase; Dominant-Negative Kinase-Deficient Brutons Tyrosine Kinase
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BTK Protein, Human (Active, M437R, sf9, His-GST)
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Cat. No.: HY-P704027
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: BTK; Tyrosine-Protein Kinase BTK Isoform (Lacking Exon 13 To 17); Prev. AGMX1; Tyrosine-Protein Kinase BTK Isoform (Lacking Exon 14); Prev. IMD1; Tyrosine-Protein Kinase BTK Isoform 52; ATK; Tyrosine-Protein Kinase BTK Isoform 51; PSCTK1; Tyrosine-Protein
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BTK Protein, Human (Active, T316A, sf9, GST)
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Cat. No.: HY-P704028
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: BTK; Tyrosine-Protein Kinase BTK Isoform (Lacking Exon 13 To 17); Prev. AGMX1; Tyrosine-Protein Kinase BTK Isoform (Lacking Exon 14); Prev. IMD1; Tyrosine-Protein Kinase BTK Isoform 52; ATK; Tyrosine-Protein Kinase BTK Isoform 51; PSCTK1; Tyrosine-Protein
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BTK Protein, Human (Active, T474I, sf9, His-GST)
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Cat. No.: HY-P704029
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: BTK; Tyrosine-Protein Kinase BTK Isoform (Lacking Exon 13 To 17); Prev. AGMX1; Tyrosine-Protein Kinase BTK Isoform (Lacking Exon 14); Prev. IMD1; Tyrosine-Protein Kinase BTK Isoform 52; ATK; Tyrosine-Protein Kinase BTK Isoform 51; PSCTK1; Tyrosine-Protein
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BTK Protein, Human (Active, T474S, sf9, GST)
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Cat. No.: HY-P704030
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: BTK; Tyrosine-Protein Kinase BTK Isoform (Lacking Exon 13 To 17); Prev. AGMX1; Tyrosine-Protein Kinase BTK Isoform (Lacking Exon 14); Prev. IMD1; Tyrosine-Protein Kinase BTK Isoform 52; ATK; Tyrosine-Protein Kinase BTK Isoform 51; PSCTK1; Tyrosine-Protein
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BTK Protein, Human (Biotinylated, L528W, sf9, Avi)
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Cat. No.: HY-P705741
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: BTK; Tyrosine-Protein Kinase BTK Isoform (Lacking Exon 13 To 17); Prev. AGMX1; Tyrosine-Protein Kinase BTK Isoform (Lacking Exon 14); Prev. IMD1; Tyrosine-Protein Kinase BTK Isoform 52; ATK; Tyrosine-Protein Kinase BTK Isoform 51; PSCTK1; Tyrosine-Protein
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BTK Protein, Human (Active, R28H, sf9, His-GST)
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Cat. No.: HY-P705743
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: BTK; Tyrosine-Protein Kinase BTK Isoform (Lacking Exon 13 To 17); Prev. AGMX1; Tyrosine-Protein Kinase BTK Isoform (Lacking Exon 14); Prev. IMD1; Tyrosine-Protein Kinase BTK Isoform 52; ATK; Tyrosine-Protein Kinase BTK Isoform 51; PSCTK1; Tyrosine-Protein
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BTK Protein, Human (Active, P190K, sf9, His-StrepII)
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Cat. No.: HY-P705745
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: BTK; Tyrosine-Protein Kinase BTK Isoform (Lacking Exon 13 To 17); Prev. AGMX1; Tyrosine-Protein Kinase BTK Isoform (Lacking Exon 14); Prev. IMD1; Tyrosine-Protein Kinase BTK Isoform 52; ATK; Tyrosine-Protein Kinase BTK Isoform 51; PSCTK1; Tyrosine-Protein
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BTK Protein, Human (Active, C481R, sf9, His-StrepII)
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Cat. No.: HY-P705746
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: BTK; Tyrosine-Protein Kinase BTK Isoform (Lacking Exon 13 To 17); Prev. AGMX1; Tyrosine-Protein Kinase BTK Isoform (Lacking Exon 14); Prev. IMD1; Tyrosine-Protein Kinase BTK Isoform 52; ATK; Tyrosine-Protein Kinase BTK Isoform 51; PSCTK1; Tyrosine-Protein
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BTK Protein, Human (Active, Y485F, sf9, His-StrepII)
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Cat. No.: HY-P705747
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: BTK; Tyrosine-Protein Kinase BTK Isoform (Lacking Exon 13 To 17); Prev. AGMX1; Tyrosine-Protein Kinase BTK Isoform (Lacking Exon 14); Prev. IMD1; Tyrosine-Protein Kinase BTK Isoform 52; ATK; Tyrosine-Protein Kinase BTK Isoform 51; PSCTK1; Tyrosine-Protein
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BTK Protein, Human (Active, Biotinylated, C481R, sf9, Avi)
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Cat. No.: HY-P705748
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: BTK; Tyrosine-Protein Kinase BTK Isoform (Lacking Exon 13 To 17); Prev. AGMX1; Tyrosine-Protein Kinase BTK Isoform (Lacking Exon 14); Prev. IMD1; Tyrosine-Protein Kinase BTK Isoform 52; ATK; Tyrosine-Protein Kinase BTK Isoform 51; PSCTK1; Tyrosine-Protein
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BTK Protein, Human (Active, Biotinylated, V416L, sf9, Avi)
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Cat. No.: HY-P705749
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: BTK; Tyrosine-Protein Kinase BTK Isoform (Lacking Exon 13 To 17); Prev. AGMX1; Tyrosine-Protein Kinase BTK Isoform (Lacking Exon 14); Prev. IMD1; Tyrosine-Protein Kinase BTK Isoform 52; ATK; Tyrosine-Protein Kinase BTK Isoform 51; PSCTK1; Tyrosine-Protein
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BTK Protein, Human (Active, Biotinylated, M437R, sf9, Avi)
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Cat. No.: HY-P705750
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: BTK; Tyrosine-Protein Kinase BTK Isoform (Lacking Exon 13 To 17); Prev. AGMX1; Tyrosine-Protein Kinase BTK Isoform (Lacking Exon 14); Prev. IMD1; Tyrosine-Protein Kinase BTK Isoform 52; ATK; Tyrosine-Protein Kinase BTK Isoform 51; PSCTK1; Tyrosine-Protein
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Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
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Capetin (28-54), human
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- Formula: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
