Vanilloloside
Based on 1 Customer Validation
Vanilloloside is a compound found in Dendrobium moniliforme. Vanilloloside has the ability to stimulate B cell proliferation and inhibit T cell proliferation in vitro.
For research use only. We do not sell to patients.
- Purity: 95.0%
- CAS No.: 74950-96-2
- Formula: C14H20O8
- Molecular Weight:316.30
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Storage:
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Caco-2 | IC50 |
<5 μg/mL
Compound: Vanilloloside
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Cytotoxicity against human Caco2 cells after 72 hrs by MTS assay
Cytotoxicity against human Caco2 cells after 72 hrs by MTS assay
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[PMID: 22032697] |
| CCD-18Co | IC50 |
<5 μg/mL
Compound: Vanilloloside
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Cytotoxicity against human CCD-18Co cells after 72 hrs by MTS assay
Cytotoxicity against human CCD-18Co cells after 72 hrs by MTS assay
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[PMID: 22032697] |
| HCT-116 | IC50 |
<5 μg/mL
Compound: Vanilloloside
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Cytotoxicity against human HCT116 cells after 72 hrs by MTS assay
Cytotoxicity against human HCT116 cells after 72 hrs by MTS assay
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[PMID: 22032697] |
Chemical Information
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CAS No. 74950-96-2
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Appearance Solid
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Molecular Weight 316.30
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Formula C14H20O8
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Color White to off-white
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SMILES
COC(C=C(C=C1)CO)=C1O[C@@H]2O[C@@H]([C@H]([C@@H]([C@H]2O)O)O)CO
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
DMSO : ≥ 50 mg/mL (158.08 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 1.25 mg/mL (3.95 mM); Clear solution
This protocol yields a clear solution of ≥ 1.25 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (12.5 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: ≥ 1.25 mg/mL (3.95 mM); Clear solution
This protocol yields a clear solution of ≥ 1.25 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (12.5 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
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%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
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%+
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+%Tween-80 + +
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%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL. * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Purity & Documentation
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Data Sheet (271 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.1616 mL | 15.8078 mL | 31.6156 mL | 79.0389 mL |
| 5 mM | 0.6323 mL | 3.1616 mL | 6.3231 mL | 15.8078 mL | |
| 10 mM | 0.3162 mL | 1.5808 mL | 3.1616 mL | 7.9039 mL | |
| 15 mM | 0.2108 mL | 1.0539 mL | 2.1077 mL | 5.2693 mL | |
| 20 mM | 0.1581 mL | 0.7904 mL | 1.5808 mL | 3.9519 mL | |
| 25 mM | 0.1265 mL | 0.6323 mL | 1.2646 mL | 3.1616 mL | |
| 30 mM | 0.1054 mL | 0.5269 mL | 1.0539 mL | 2.6346 mL | |
| 40 mM | 0.0790 mL | 0.3952 mL | 0.7904 mL | 1.9760 mL | |
| 50 mM | 0.0632 mL | 0.3162 mL | 0.6323 mL | 1.5808 mL | |
| 60 mM | 0.0527 mL | 0.2635 mL | 0.5269 mL | 1.3173 mL | |
| 80 mM | 0.0395 mL | 0.1976 mL | 0.3952 mL | 0.9880 mL | |
| 100 mM | 0.0316 mL | 0.1581 mL | 0.3162 mL | 0.7904 mL |
Vanilloloside Related Classifications
HY-N15586 Related Classifications
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