YM-26734

Cat. No.: HY-108609: FAQs
Data Sheet Handling Instructions

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YM-26734 is a competitive inhibitor of secretory phospholipase A² (PLA²) that exhibits a broad inhibitory profile to several PLA2s.

For research use only. We do not sell to patients.

YM-26734 Chemical Structure

CAS No. : 144337-18-8

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5 mg	USD 350	Ask For Quote & Lead Time

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This product is a controlled substance and not for sale in your territory.

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Phospholipase A PLD

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Description

YM-26734 is a competitive inhibitor of secretory phospholipase A² (PLA²) that exhibits a broad inhibitory profile to several PLA2s^[1].

IC₅₀ & Target

sPLA2

Molecular Weight

730.97

Formula

C₄₅H₆₂O₈

CAS No.

144337-18-8

SMILES

OC1=C(C(CCCCCCCCCCC)=O)C(O)=C(C(CCCCCCCCCCC)=O)C(O)=C1C2CC(C3=CC=C(O)C=C3)OC4=CC(O)=CC=C24

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Miyake A, et al. Suppression of inflammatory responses to 12-O-tetradecanoyl-phorbol-13-acetate and carrageenin by YM-26734, a selective inhibitor of extracellular group II phospholipase A2. Br J Pharmacol. 1993 Sep;110(1):447-53. [Content Brief]

YM-26734 Related Classifications

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Dilution Calculator

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

YM-26734144337-18-8YM26734YM 26734PhospholipaseInhibitorinhibitorinhibit

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