1. Others
  2. Others
  3. (5E,9E,13E)-Teprenone

(5E,9E,13E)-Teprenone (Synonyms: (5E,9E,13E)-Geranylgeranylacetone)

Cat. No.: HY-B0779A Purity: 99.88%
Handling Instructions

(5E,9E,13E)-Teprenone ((5E,9E,13E)-Geranylgeranylacetone) is an isomer of Teprenone with antiulcer activity. (5E,9E,13E)-Teprenone induces transcriptional activation of HSP genes that may increase gastric mucosal defense at conditions of stress.

For research use only. We do not sell to patients.

(5E,9E,13E)-Teprenone Chemical Structure

(5E,9E,13E)-Teprenone Chemical Structure

CAS No. : 3796-63-2

Size Price Stock Quantity
Free Sample (0.5-1 mg)   Apply now  
10 mM * 1 mL in DMSO USD 165 In-stock
Estimated Time of Arrival: December 31
10 mg USD 150 In-stock
Estimated Time of Arrival: December 31
50 mg USD 450 In-stock
Estimated Time of Arrival: December 31
100 mg USD 750 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of (5E,9E,13E)-Teprenone:

Top Publications Citing Use of Products
  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

(5E,9E,13E)-Teprenone ((5E,9E,13E)-Geranylgeranylacetone) is an isomer of Teprenone with antiulcer activity. (5E,9E,13E)-Teprenone induces transcriptional activation of HSP genes that may increase gastric mucosal defense at conditions of stress[1].

In Vitro

(5E,9E,13E)-Teprenone might transiently activate the transcription of HSP70 gene[1].
The heat shock element–binding activity reflects the activation of heat shock factor 1 in response to (5E,9E,13E)-Teprenone[1].

In Vivo

(5E,9E,13E)-Teprenone induces hat sock proteins accumulations in rat gastric mucosa[1].

Animal Model: Male Wister strain rats (≈250 g)[1]
Dosage: 200 mg/kg
Administration: Oral administration
Result: Caused accumulations of all of HSP90, HSP70, HSC70 and HSP60 within 60 minutes.
Molecular Weight

330.55

Formula

C₂₃H₃₈O

CAS No.

3796-63-2

SMILES

CC(CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/CC/C=C(C)\C)=O.[(E)].[(E)].[(E)]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

Solvent & Solubility
In Vitro: 

DMSO : 5 mg/mL (15.13 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.0253 mL 15.1263 mL 30.2526 mL
5 mM 0.6051 mL 3.0253 mL 6.0505 mL
10 mM 0.3025 mL 1.5126 mL 3.0253 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 0.5 mg/mL (1.51 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 0.5 mg/mL (1.51 mM); Clear solution

*All of the co-solvents are provided by MCE.
References

Purity: 99.88%

  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.
  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

(5E,9E,13E)-Teprenone(5E,9E,13E)-GeranylgeranylacetoneOthersTeprenoneHSPHeatshockproteinsgastricmucosaldefenseInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product name

 

Salutation

Applicant name *

 

Email address *

Phone number *

 

Organization name *

Country or Region *

 

Requested quantity *

Remarks

Bulk Inquiry

Inquiry Information

Product name:
(5E,9E,13E)-Teprenone
Cat. No.:
HY-B0779A
Quantity:
MCE Japan Authorized Agent: