6-OAU (Standard)
6-OAU (Standard) (GTPL5846 (Standard)) is the analytical standard of 6-OAU (HY-12764). This product is intended for research and analytical applications. 6-OAU (GTPL5846) (6-n-octylaminouracil) is an GPR84 (G protein-coupled receptor 84) agonist, with an EC50 value of 105 nM. 6-OAU works as a chemoattractant to both PMNs and macrophages, and amplifies the proinflammatory cytokine IL-8, shows proinflammatory function. 6-OAU also displays anti-bacterial function.
For research use only. We do not sell to patients.
- Purity : 98%
- CAS No.: 83797-69-7
- Formula: C12H21N3O2
- Molecular Weight:239.31
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Product Information
-
Chemical Information
- Purity & Documentation
-
Help & FAQs
-
HY-12764
6-OAUGPR84 Agonist -
HY-112562
GPR84 antagonist 8GPR84 Antagonist -
HY-15589
GW9508GPR40 Agonist -
HY-19838
JNJ-63533054GPR139 Agonist -
HY-15565
APD668GPR119 Agonist -
HY-12336
NIBR189EBI2 Antagonist -
HY-116522
AR420626FFAR3 Agonist -
HY-15342
TimapiprantProstaglandin Receptor Antagonist -
HY-15291
MBX-2982GPR119 Agonist -
HY-101787
TP-024GPR52 Agonist -
HY-101784
NE 52-QQ57GPR4 Antagonist -
HY-103252
Monomethyl fumarateGPR109A Agonist
Product Information
Information
Application
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
-
CAS No. 83797-69-7
-
Molecular Weight 239.31
-
Formula C12H21N3O2
-
SMILES
O=C1NC(C=C(NCCCCCCCC)N1)=O
-
Synonyms
GTPL5846 (Standard)
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Suzuki M, et al. Medium-chain fatty acid-sensing receptor, GPR84, is a proinflammatory receptor. J Biol Chem. 2013 Apr 12;288(15):10684-91. [Content Brief]
[2]. Reyes AWB, et al. Immune-metabolic receptor GPR84 surrogate and endogenous agonists, 6-OAU and lauric acid, alter Brucella abortus 544 infection in both in vitro and in vivo systems. Microb Pathog. 2021 Sep. 158:105079. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
6-OAU (Standard) Related Classifications
HY-12764R Related Classifications
Powered by Bioz