1. Metabolic Enzyme/Protease
  2. Lipoxygenase
  3. AZD 4407

AZD 4407 (Synonyms: ZD 4407)

Cat. No.: HY-U00217
Handling Instructions

AZD 4407 is a potent 5-lipoxygenase inhibitor.

For research use only. We do not sell to patients.

AZD 4407 Chemical Structure

AZD 4407 Chemical Structure

CAS No. : 166882-70-8

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Description

AZD 4407 is a potent 5-lipoxygenase inhibitor.

IC50 & Target

5-Lipoxygenase

 

In Vitro

In view of the powerful spasmogenic actions of leukotrienes in vascular and bronchial tissue, drugs which block their biosynthesis by inhibiting 5-lipoxygenase may have therapeutic potential in a variety of inflammatory conditions including inflammatory arthropothies, asthma, psoriasis, and inflammatory bowel disease. One such compound is AZD 4407 (ZD4407)[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

375.50

Formula

C₁₉H₂₁NO₃S₂

CAS No.

166882-70-8

SMILES

O=C1N(C)C2=C(C=C(SC3=CC([[email protected]]4(O)C[[email protected]](C)OCC4)=CS3)C=C2)C1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Keywords:

AZD 4407ZD 4407AZD4407AZD-4407ZD4407ZD-4407LipoxygenaseLOXInhibitorinhibitorinhibit

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