1. Membrane Transporter/Ion Channel
    Neuronal Signaling
  2. iGluR
  3. GNE 0723

GNE 0723 

Cat. No.: HY-108337
Handling Instructions

GNE 0723 is a brain permeable positive allosteric modulator of NMDAR, with an EC50 of 21 nM for GluN2A, 7.4 and 6.2 μM for GluN2C and GluN2D, respectively.

For research use only. We do not sell to patients.

GNE 0723 Chemical Structure

GNE 0723 Chemical Structure

CAS No. : 1883518-31-7

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Description

GNE 0723 is a brain permeable positive allosteric modulator of NMDAR, with an EC50 of 21 nM for GluN2A, 7.4 and 6.2 μM for GluN2C and GluN2D, respectively.

IC50 & Target

EC50: 21 nM (GluN2A), 7.4 μM (GluN2C), 6.2 μM (GluN2D)[1]

In Vitro

GNE 0723 is a brain permeable positive allosteric modulator of NMDAR, with an EC50 of 21 nM for GluN2A, 7.4 and 6.2 μM for GluN2C and GluN2D, respectively[1].

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
Molecular Weight

467.78

Formula

C₁₆H₈ClF₆N₅OS

CAS No.

1883518-31-7

SMILES

N#C[[email protected]]1[[email protected]](C2=C(C(F)(F)F)SC3=NC(CN4N=C(C(F)(F)F)C=C4Cl)=CC(N32)=O)C1

Shipping

Room temperature in continental US; may vary elsewhere

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Product Name:
GNE 0723
Cat. No.:
HY-108337
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GNE 0723

Cat. No.: HY-108337