2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-W050151
    2,5-Di-tert-butyl-1,4-benzoquinone 2460-77-7 99.50%
    2,5-Di-tert-butyl-1,4-benzoquinone is a potent antibacterial agent that defends the emerging antibacterial resistance, which is found in marine Streptomyces sp. VITVSK1. 2,5-Di-tert-butyl-1,4-benzoquinone is also a potent inhibitor of RNA polymerase.
    2,5-Di-tert-butyl-1,4-benzoquinone
  • HY-W060074
    1-Acetyl-β-carboline 50892-83-6
    1-Acetyl-β-carboline is a metabolite of Streptomyces kasugaensis and antibacterial agent. 1-Acetyl-β-carboline increases tyrosinase activity, reduces ERK phosphorylation. 1-Acetyl-β-carboline exhibits antibacterial activity against methicillin-resistant Staphylococcus aureus (MRSA) strains with MICs ranging from 128 to 256 ug/mL. 1-Acetyl-β-carboline increases the melanin.
    1-Acetyl-β-carboline
  • HY-W070884
    nAChR-IN-2 3000-75-7
    nAChR-IN-2 (Compound 2) is an inhibitor of insect nicotinic acetylcholine receptors (nAChR). nAChR-IN-2 inhibits the binding of α-bungarotoxin (HY-P1264) to the ACh site of insect nAChR in honeybee heads, with an IC50 of 360 μM. nAChR-IN-2 also inhibits the binding of Phencyclidine to the NCB/PCP site of insect nAChR in honeybee heads, with an IC50 of 84 μM.
    nAChR-IN-2
  • HY-W072459
    6'-Hydroxydihydrocinchonidine 5962-19-6 98.85%
    6'-Hydroxydihydrocinchonidine is a metabolite of Quinine (HY-D0143) (antimalarial agent).
    6'-Hydroxydihydrocinchonidine
  • HY-W087058
    1,4-Di-tert-butylbenzene 1012-72-2
    1,4-Di-tert-butylbenzene is a volatile compound identified in the hexane extracts of corn cob and green millet. 1,4-Di-tert-butylbenzene shows potent inhibition against receptor proteins of Bacterial type II topoisomerase (4PLB and LpxC) in docking analysis.
    1,4-Di-tert-butylbenzene
  • HY-W093378
    Silver(I) sulfide 21548-73-2 98%
    Silver (I) sulfide is a biochemical reagent. Silver (I) sulfide nanoparticles exert Antibacterial effects against a variety of resistant bacteria, including Gram-positive and Gram-negative bacteria. Silver (I) sulfide can be used in the research of bacterial infections, such as infections caused by Staphylococcus aureus, Streptococcus agalactiae, Escherichia coli and Pseudomonas species.
    Silver(I) sulfide
  • HY-W097659
    Antileishmanial agent-32 16929-60-5
    Antileishmanial agent-32 (Compound 12) exhibits a weak antileishmanial activity that inhibits stationary promastigote forms of L. amazonensis with an IC50 >15 μM. Antileishmanial agent-32 exhibits cytotoxicity towards murine macrophages.
    Antileishmanial agent-32
  • HY-W109038
    4-Propylcatechol 2525-02-2 99.74%
    4-Propylcatechol is an Allylpyrocatechol (HY-124127) analog. 4-Propylcatechol shows anti-malarial activity against Plasmodium falciparum CDC-1 with an IC50 of 32 µM.
    4-Propylcatechol
  • HY-W111370
    2-Nitroamino-2-imidazoline 5465-96-3 ≥98.0%
    2-Nitroamino-2-imidazoline is an intermediate in the synthesis of the neonicotinoid insecticide Imidacloprid (HY-B0838).
    2-Nitroamino-2-imidazoline
  • HY-W128400
    3′-Deoxy-3′-fluoroguanosine 123402-21-1 99.29%
    3′-Deoxy-3′-fluoroguanosine exhibits antiviral activity against tick-borne encephalitis virus (TBEV), through interaction with NS5B RdRp of HCV, resulting in suppression of viral RNA synthesis by disruption of further extension of the replicating viral RNA.
    3′-Deoxy-3′-fluoroguanosine
  • HY-W130307
    Tricosane 638-67-5 98.0%
    Tricosane (N-Tricosane) is a straight-chain alkane. Tricosane exhibits a certain degree of antibacterial activity against E. coli.
    Tricosane
  • HY-W154397
    Permethrinic acid methyl ester 61898-95-1
    Permethrinic Acid Methyl Ester is a derivative of the insecticide Permethrin (HY-B0887). Permethrin is an insecticide, an acaricide, and a highly selective inhibitor of mitochondrial complex I.
    Permethrinic acid methyl ester
  • HY-W160679
    7-(Carboxymethoxy)-4-methylcoumarin 64700-15-8 99.61%
    7-(Carboxymethoxy)-4-methylcoumarin (Compound VIIIa) is the antibacterial and antifungal agent that exhibits inhibitory activity against S. aureus, B. cereus, S. lutea, C. albicans, C. glabrata, and C. parapsilosis.
    7-(Carboxymethoxy)-4-methylcoumarin
  • HY-W210476
    Somantadine 79594-24-4 98.58%
    Somantadine, an adamantane derivative, is an antiviral agent with high cross-reactivity with anti-amantadine monoclonal antibodies. Somantadine can be used for research of coronavirus-related diseases.
    Somantadine
  • HY-W248922
    2,6-Dibromo-4-(hydroxymethyl)phenol 2316-62-3 99.87%
    2,6-Dibromo-4-(hydroxymethyl) phenol (Compound 5) acts as a selective inhibitor of Saccharomyces cerevisiae glucose-6-phosphate dehydrogenase, with an IC50 value of 50.2 μM, and shows no activity against Leuconostoc mesenteroides glucose-6-phosphate dehydrogenase.
    2,6-Dibromo-4-(hydroxymethyl)phenol
  • HY-W320276
    Dill apiole 484-31-1 99.18%
    Dill apiole is an aromatic ether, which is an important aroma component in herbs and spices such as dill (Anethum graveolens), parsley (Petroselinum crispum) and basil (Perilla frutescens). Dill apiole exhibits antimicrobial activity against Aspergillus parasiticus and Aedes aegypti.
    Dill apiole
  • HY-W327808
    DL-Lanthionine 3183-08-2
    DL-Lanthionine is a distinctive amino acid and a monosulfide counterpart to cystine, playing a vital role as a component of peptide antibiotics known as lantiobiotics, which encompass well-known examples such as nisin and subtilin.
    DL-Lanthionine
  • HY-W357093
    2-Chloro-2-deoxy-D-glucose 14685-79-1 98%
    2-Chloro-2-deoxy-D-glucose is a 2-substituted glucose analog. 2-Chloro-2-deoxy-D-glucose inhibits the in vitro growth of P. falciparum. 2-Chloro-2-deoxy-D-glucose against a CQR strain with an IC50 value of 8.5 nM at the glucose concentration 5 mM.
    2-Chloro-2-deoxy-D-glucose
  • HY-W391596
    Pamaquine 491-92-9 98.84%
    Pamaquine is an 8-aminoquinoline antimalarial agent. Pamaquine has neurotoxicity and can damage specific neuro-anatomical structures, leading to deficits of neurologic function in Rhesus monkeys models.
    Pamaquine
  • HY-W414596
    Metconazole 125116-23-6 98%
    Metconazole is a 14α-demethylation inhibitor (DMI) fungicide. Metconazole inhibits fungal ergosterol biosynthesis, inhibits mycelial growth and conidial germ tube elongation. Metconazole reduces antioxidant enzyme activities. Metconazole reduces occurrence of Fusarium crown rot in wheat.
    Metconazole
Cat. No. Product Name / Synonyms Application Reactivity