2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-W420337
    Fluopimomide 1309859-39-9
    Fluopimomide (LH2010A) is a potent pesticide, widely used for agricultural pest management. Fluopimomide adversely affects the nematodes growth, locomotive behaviors, reproduction, and lifespan, accompanying with enhanced of reactive oxygen species (ROS) generation, lipid and lipofuscin accumulation, and malondialdehyde content. Fluopimomide inhibits antioxidant systems in the nematodes.
    Fluopimomide
  • HY-W473763
    3-Methoxy-2,5-toluquinone 611-68-7 98.01%
    3-Methoxy-2, 5-toluquinone is an antibacterial agent with moderate anti-bacterial and fungal effects.
    3-Methoxy-2,5-toluquinone
  • HY-W513778
    (+)-trans-Chrysanthemic acid 4638-92-0 99.85%
    (+)-trans-Chrysanthemic acid is a component of pyrethroids that inhibits Orlando strain mosquitoes.
    (+)-trans-Chrysanthemic acid
  • HY-W516735
    Sedaxane 874967-67-6 98.49%
    Sedaxane is a new broad-spectrum seed treatment fungicide. Sedaxane inhibits fungal respiration by binding to the succinate dehydrogenase complex in fungal mitochondria. Sedaxane has broad-spectrum activity against a variety of seed-borne and soil-borne fungi. Sedaxane can be used in the study of barley loose smut and barley stripe disease.
    Sedaxane
  • HY-W554514
    D-Homoserine lactone 51744-82-2 98%
    D-Homoserine lactone is a signaling molecule with the activity of regulating bacterial quorum sensing. The chemical structure of D-Homoserine lactone makes it a potential regulator of the AHL synthase RhlI. D-Homoserine lactone has been shown to inhibit the activity of RhlI, thereby affecting the bacterial quorum sensing signaling pathway. D-Homoserine lactone is also an enantiomer of L-homoserine lactone and is used as an inhibitor of serine hydroxymethyltransferase.
    D-Homoserine lactone
  • HY-W587414
    Neospiramycin I 70253-62-2
    Neospiramycin I is a macrolide antibiotic and a derivative of Spiramycin I (HY-N7141). Neospiramycin I is effective against the macrolide-sensitive KB210 strain of S. aureus, but ineffective against the macrolide-resistant KB224 strain, with minimum inhibitory concentrations (MIC) of 3.12 and greater than 100 µg/mL, respectively; it is also effective against B. cereus, B. subtilis, M. luteus, E. coli, and K. pneumoniae, with respective MIC values of 1.56, 3.12, 3.12, 0.2, 50, and 12.5 µg/mL. Neospiramycin I binds to the ribosomes of E. coli, with an inhibitory concentration 50 (IC50) of 1.2 µM. It protects mice from death in a type III S. pneumoniae infection model, with an effective dose 50 (ED50) of 399.8 mg/kg.
    Neospiramycin I
  • HY-W643128
    Carlina oxide 502-22-7 98%
    Carlina oxide is an AChE inhibitor and antioxidant that kills Culex pipiens larvae (LC50=1.39 μg/mL). Carlina oxide is cytotoxic to vertebrate cells, human dermis, HCT116 and MDA-MB231 cell lines.
    Carlina oxide
  • HY-W653962
    Triclosan-13C6 2726926-25-4 99.51%
    Triclosan-13C6 is 13C labeled Triclosan. Triclosan is a broad-spectrum antibacterial agent that inhibits bacterial fatty acid synthesis at the enoyl-acyl carrier protein reductase (FabI) step. Triclosan inhibits E. coli enoyl-acyl carrier protein reductase (FabI) and FabI containing a glycine-to-valine substitution at position 93 (FabIG93V) with IC50s of 2 μM and 10 μM, respectively. Triclosan causes apoptotic effect in cultured rat neural stem cells (NSC). Triclosan exacerbates colitis and colitis-associated colorectal tumorigenesis in animal models.
    Triclosan-13C6
  • HY-W654020
    Propyl paraben-13C6 2075718-26-0 99.99%
    Propyl paraben-13C6 (Propyl parahydroxybenzoate-13C6) is 13C labeled Propylparaben. Propylparaben (Propyl parahydroxybenzoate) is an antibacterial preservative that can be produced by plants and bacteria. Propylparaben is commonly used in cosmetics, pharmaceuticals and foods. Propylparaben disrupts follicular growth and steroidogenic function by altering cell cycle, apoptosis and steroidogenic pathways. Propylparaben also reduced sperm count and motility in rats.
    Propyl paraben-13C6
  • HY-W654157
    Dicloxacillin-13C4 sodium hydrate
    Dicloxacillin-13C4 sodium hydrate is the 13C-labeled Dicloxacillin Sodium hydrate (HY-B0977). Dicloxacillin Sodium hydrate (Dicloxacillin sodium salt monohydrate) is a narrow-spectrum β-Lactam antibiotic of the penicillin class, is used to study infections caused by susceptible Gram-positive bacteria, active against beta-lactamase-producing organisms such as Staphylococcus aureus.
    Dicloxacillin-13C4 sodium hydrate
  • HY-W654255
    Mandelic Acid-13C8 2701643-58-3 98.17%
    Mandelic Acid-13C8 ((±)-Mandelic acid-13C8) is the 13C-labeled Mandelic acid (HY-W015591). Mandelic acid ((±)-Mandelic acid), an alpha-hydroxycarboxylic acid, has been widely used as an intermediate of pharmaceutical and fine chemicals. Mandelic acid shows antimicrobial activity and has been used for the research of urinary tract infections and vaginal trichomoniasis. Mandelic acid exhibits high sperm-immobilizing activity and low vaginal irritation.
    Mandelic Acid-13C8
  • HY-W654282
    Myclobutanil-d9 99.94%
    Myclobutanil-d9 is deuterium labeled Myclobutanil. Myclobutanil is a conazole class fungicide widely used as an agrichemical.
    Myclobutanil-d9
  • HY-W654329
    Protionamide-d7 2468639-68-9
    Protionamide-d7 is deuterium labeled Prothionamide. Protionamide (prothionamide) acts on tuberculosis and leprosy.
    Protionamide-d7
  • HY-W686763
    Triacetylphloroglucinol 2161-87-7 99.95%
    Triacetylphloroglucinol (2,4,6-Triacetylphloroglucinol) is a C3-symmetric three-dimensional bridged ligand. It has been used in the synthesis of various compounds including trinuclear vanadium Schiff base complexes, copper complexes and anthelmintics.
    Triacetylphloroglucinol
  • HY-W704598
    Methyl 3-hydroxydodecanoate 72864-23-4 99%
    Methyl 3-hydroxydodecanoate is a poly (3-hydroxyalkanoate) monomer. Methyl 3-hydroxydodecanoate can be produced with the involvement of Pseudomonas putida Bet001.
    Methyl 3-hydroxydodecanoate
  • HY-W706180
    (±)-Triadimefon-d4 99.47%
    (±)-Triadimefon-d4 is deuterium labeled Triadimefon. Triadimefon is a triazole fungicide used to control powdery mildew, rusts, and other fungal pests on grains, fruit and vegetable crops, turf, shrubs, and trees. Triadimefon inhibits lanosterol 14α-demethylase, interfering with oxidative demethylation reactions in the ergosterol biosynthesis pathway of fungi, and also blocks gibberellin biosynthesis.
    (±)-Triadimefon-d4
  • HY-W712028
    α-Thujene 2867-05-2 98%
    α-Thujene is a natural fragrance with antifungal properties. It is extracted from eucalyptus trees. α-Thujene is recorded against Macrophomina phaseolina (85%) followed by Botrydiplodia theobromae (84%) which are better in comparison with standard Nystatin.
    α-Thujene
  • HY-W712567
    Adenine-15N5 hydrochloride 2095709-78-5 99.84%
    Adenine-15N5 (6-Aminopurine-15N5) hydrochloride is the 15N-labeled Adenine hydrochloride (HY-B0152A). Adenine hydrochloride (6-Aminopurine hydrochloride), a purine, is one of the four nucleobases in the nucleic acid of DNA. Adenine hydrochloride acts as a chemical component of DNA and RNA. Adenine hydrochloride also plays an important role in biochemistry involved in cellular respiration, the form of both ATP and the cofactors (NAD and FAD), and protein synthesis.
    Adenine-15N5 hydrochloride
  • HY-W726127
    Propamocarb hydrochloride 25606-41-1 99.26%
    Propamocarb hydrochloride is a systemic fungicide. Propamocarb hydrochloride is widely used to protect cucumbers, tomatoes and other plants from pathogens.
    Propamocarb hydrochloride
  • HY-W744739
    Betulinic acid-d3 99.9%
    Betulinic acid-d3 (Lupatic acid-d3) is a deuterium labeled Betulinic acid (HY-10529). Betulinic acid is a natural pentacyclic triterpenoid, acts as a eukaryotic topoisomerase I inhibitor, with an IC50 of 5 μM, and possesses anti-HIV, anti-malarial, anti-inflammatory and anti-tumor properties. Betulinic acid can cross the blood-brain barrier.
    Betulinic acid-d3
Cat. No. Product Name / Synonyms Application Reactivity