2. Infection

Infection

Infection

Related Products

PDF 70.44 MB

Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-P992123
    Ombetoxabart 3054523-85-9 98%
    Ombetoxabart is a humanized IgG1-κ monoclonal antibody targeting TcdB (Clostridioides difficile toxin B), which exerts its function by neutralizing the toxicity of TcdB. Ombetoxabart can be used for the study of Clostridioides difficile infection.
    Ombetoxabart
  • HY-P992134
    Tepsababart 3050776-33-2 98%
    Tepsababart is a humanized monoclonal antibody against staphylococcal clumping factor A, which can be used in research on antibacterial infections.
    Tepsababart
  • HY-P992154
    Ricefidase 98%
    Ricefidase (KJ-103) is a recombinant human immunoglobulin G-degrading enzyme. Ricefidase efficiently cleaves human IgG at the hinge region. Ricefidase rapidly reduces IgG levels. Ricefidase has low immunogenicity and clears AAV neutralizing antibodies. Ricefidase is applicable to research related to desensitization of all IgG subclasses and improvement of the suitability of AAV-based gene therapy.
    Ricefidase
  • HY-P992155
    Arevirumab 98%
    Arevirumab (Arevirumab-3) is a pan-lineage neutralizing human monoclonal antibody cocktail (8.9F, 12.1F, 37.D). Arevirumab protects cynomolgus monkeys from severe Lassa fever caused by lineage II and III LASV isolates. Arevirumab is applicable to research related to Lassa fever.
    Arevirumab
  • HY-P992174
    ADI-14359 98%
    ADI-14359 is an antibody that binds to RSV postF, with a KD value of 387 nM, and exhibits non-neutralizing activity. ADI-14359 binds to antigenic site I on RSV postF through interactions of its conserved CDR H3 motif, germline-encoded IGKV1-39 light chain residues and heavy chain residues, where the light chain mediates preferential binding to postF by conflicting with the rearranged preF region. ADI-14359 can be used in studies related to respiratory syncytial virus (RSV) infection.
    ADI-14359
  • HY-P992175
    ADI-14448 98%
    ADI-14448 is a RSV prefusion fusion glycoprotein inhibitor and HMPV fusion glycoprotein inhibitor, with a Kd of 3.8 × 10-10 M for RSV preF. ADI-14448 binds to epitope III of RSV preF, thereby blocking viral infection. ADI-14448 neutralizes RSV subtype A and HMPV subtype A1. ADI-14448 can be used in studies related to respiratory syncytial virus infection and metapneumovirus infection.
    ADI-14448
  • HY-P992281
    Anti-Nucleocapsid Antibody (N-18) 98%
    Anti-Nucleocapsid Antibody (N-18) is an antibody targeting Nucleocapsid, a structural protein of coronaviruses. Anti-Nucleocapsid Antibody (N-18) is applicable to studies on SARS-CoV-2 infection.
    Anti-Nucleocapsid Antibody (N-18)
  • HY-P992282
    Anti-Nucleocapsid Antibody (N-P10) 98%
    Anti-Nucleocapsid Antibody (N-P10) is a highly specific SARS-CoV-2 Nucleocapsid (N) protein-targeted recombinant monoclonal antibody. Anti-Nucleocapsid Antibody (N-P10) can be used for research on SARS-CoV-2 infection.
    Anti-Nucleocapsid Antibody (N-P10)
  • HY-P992283
    Anti-Nucleocapsid Antibody (N-P11) 98%
    Anti-Nucleocapsid Antibody (N-P11) is a highly specific SARS-CoV-2 Nucleocapsid (N) protein-targeted recombinant monoclonal antibody. Anti-Nucleocapsid Antibody (N-P11) can be used for research on SARS-CoV-2 infection.
    Anti-Nucleocapsid Antibody (N-P11)
  • HY-P992301
    Anti-RSV F Antibody (R4.C6) 98%
    Anti-RSV F Antibody (R4.C6) is a monoclonal antibody against RSV F, with a Kd of 0.34 nM for the post-fusion RSV F trimer. Anti-RSV F Antibody (R4.C6) recognizes a unique neutralizing epitope spanning epitopes II and IV on both pre-fusion and post-fusion RSV F. Anti-RSV F Antibody (R4.C6) can be used in studies related to respiratory syncytial virus infection.
    Anti-RSV F Antibody (R4.C6)
  • HY-P992351
    ELB021 98%
    ELB021 is an antibody inhibitor targeting the CD160 checkpoint. ELB021 specifically binds to CD160 on the cell surface and blocks its immune checkpoint pathway, thereby stimulating innate and adaptive anti-tumor immune responses. ELB021 effectively eliminates CD160-expressing cancer cells by enhancing T cell proliferation and CD8+ T cell-mediated cytotoxicity. Independent of PD-1 regulation, ELB021 is applicable to research related to B-cell leukemia and HIV-1 infection.
    ELB021
  • HY-P992423
    NIAID RSVF2-5 98%
    NIAID RSVF2-5 is a human monoclonal antibody fragment. NIAID RSVF2-5 binds to conserved, distinct conformational epitopes on RSV fusion glycoprotein, and shows activity against RSV subgroup A and B strains. NIAID RSVF2-5 reduces pulmonary and lung viral titers in RSV-infected rodents. NIAID RSVF2-5 can be used for the research of respiratory syncytial virus infection.
    NIAID RSVF2-5
  • HY-P992458
    SBT8230 98%
    SBT8230 is an ASGR1-targeted TLR8 agonist and an ASGR1-TLR8 immune TAC conjugate. SBT8230 achieves liver enrichment via conjugation with an anti-ASGR1 antibody, activates myeloid cells and induces anti-HBV immune responses. SBT8230 is applicable to research on chronic hepatitis B infection. The corresponding isotype control is: Human lgG1 kappa,lsotype Control (HY-P99001).
    SBT8230
  • HY-P992482
    VIR-2482 98%
    VIR-2482 is a monoclonal antibody targeting influenza A hemagglutinin (HA). VIR-2482 is generated by introducing LS mutations (M428L/N434S) into the Fc region of MEDI8852 (HY-P991446). VIR-2482 binds to the conserved HA stem epitope across all 18 influenza A HA subtypes, neutralizes a broad spectrum of H1N1 and H3N2 strains, binds to FcγRIIIa, FcγRIIa and C1q, and induces antibody-dependent cellular cytotoxicity and complement-dependent cytotoxicity. VIR-2482 reduces morbidity and mortality caused by seasonal influenza A strains and provides prophylactic protection in mice. VIR-2482 can be used in research related to influenza A disease.
    VIR-2482
  • HY-U00035R
    MGB-BP-3 (Standard) 1000277-08-6
    Sinapine (thiocyanate) (Standard) is the analytical standard of Sinapine (thiocyanate). This product is intended for research and analytical applications. Sinapine thiocyanate is an alkaloid isolated from seeds of the cruciferous species. Sinapine thiocyanate exhibits anti-inflammatory, anti-oxidant, anti-tumor, anti-angiogenic and radio-protective effects. Sinapine thiocyanate is also an acetylcholinesterase (AChE) inhibitor and can be used for the research of Alzheimer’s disease, ataxia, myasthenia gravis, and Parkinson’s disease.
    MGB-BP-3 (Standard)
  • HY-U00058R
    Diflucortolone valerate (Standard) 59198-70-8
    Diflucortolone valerate (Standard) is the analytical standard of Diflucortolone valerate. This product is intended for research and analytical applications. Diflucortolone valerate is a powerful corticosteroid used topically for the research of various skin diseases.
    Diflucortolone valerate (Standard)
  • HY-U00075A
    Indanazoline hydrochloride 40507-80-0 98%
    Indanazoline (hydrochloride) is an orally active imidazoline derivative. Indanazoline (hydrochloride) has a LD50 of 481 mg/kg in rat model. Indanazoline (hydrochloride) can be studied in research on rhinitis.
    Indanazoline hydrochloride
  • HY-U00154R
    Cefuracetime (Standard) 39685-31-9
    Cefuracetime (Standard) (SKF81367 (Standard)) is the analytical standard of Cefuracetime (HY-U00154). This product is intended for research and analytical applications. Cefuracetime is a cephalosporin antibiotic.
    Cefuracetime (Standard)
  • HY-U00295A
    Melarsonyl dipotassium 13355-00-5 98%
    Melarsonyl dipotassium (Melarsonic acid dipotassium) is an anthelmintic agent which can inhibit parasite potently.
    Melarsonyl dipotassium
  • HY-W007704
    Methyl cyclohexanecarboxylate 4630-82-4 99.29%
    Methyl cyclohexanecarboxylate is a compound related to 2-cyclohexenylcarbonyl CoA. Methyl cyclohexanecarboxylate is produced during the incubation of 2-cyclohexenylcarbonyl CoA with cell-free extracts of Streptomyces collinus.
    Methyl cyclohexanecarboxylate
Cat. No. Product Name / Synonyms Application Reactivity